• 방사선산업학회지
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• 제12권4호
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• pp.349-353
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• 2018

Metronidazole (MD), which is used as an antibiotic, is largely used as an oral and skin application agent, and has inhibiting effect on the production of the fungus causing malodor. However, the maximum drug inclusion concentration is 0.75% of skin ointment in commercially available. In this study, hydrogels containing high concentration of metronidazole were prepared by using radiation crosslinking technique based on biocompatible polymers, and release characteristics and antimicrobial properties were evaluated. This study was preliminary carried out to investigate whether it could be used effectively as antibacterial dressing materials.

• 방사선산업학회지
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• 제5권1호
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• pp.41-46
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• 2011

Polyacrylonitrile (PAN) fibers are the most widely used precursor of the materials for carbon fibers. The conventional process of carbon fibers from PAN precursor fiber includes two step; stabilization at low temperature and carbonization at high temperature. Compared to thermal stabilization, the stabilization process by electron beam (E-beam) irradiation is a advanced and brief method. However, a stabilization by E-beam irradiation was required a high dose (over 5,000 kGy) and spend over 1.5 hr (1.14 MeV, 1 mA). In the present work the main goal is exploring a quick stabilization process by cotrolling E-beam currents. The effect of various E-beam currents on stabilization of PAN precursor fiber was studied by gel fraction test, thermo gravimertic analysis (TGA), differential scanning calorimetry (DSC), tensile strength, and scanning electron microscopy (SEM) images.

• 방사선산업학회지
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• 제6권3호
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• pp.199-204
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• 2012

• 방사선산업학회지
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• 제7권1호
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• pp.45-49
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• 2013

In tissue engineering application, a fibrous structure of scaffolds has been issued as an alternative system to regulate cell survival and tissue regeneration, and electrospinning technique has been popularly used to generate fibrous meshes or sheets mimicking the structure of native extracellular matrix (ECM). However, recent strategy in the scaffold development is expanded to provide the structural property as well as a biological property of native ECM, a variety of surface modification techniques have been used to introduce biological property. In this study, we developed biomimetic poly(L-lactide-co-${\varepsilon}$-caprolactone) (PLCL) nano- and micro-fibrous scaffolds as a unique platform with structural and biological properties with native ECM using electrospinning method and gamma-ray irradiation. Surface morphology of the scaffolds was observed by scanning electron microscopy, and alteration of surface property was evaluated with toluidine blue O staining, water contact angle measurement and ATR-FTIR analysis.

• 방사선산업학회지
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• 제5권3호
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• pp.273-277
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• 2011

This study evaluated the cytotoxicity and anti-inflammatory activities of natural herbal extracts including Houttuynia cordata and Eucommia ulmoides against human mast cell (HMC-1). Houttuynia cordata (HC) and Eucommia ulmoides(EU) were extracted with distilled water (at $75^{\circ}C$) and then freeze-dried for 5 days. Finally, the mixture of HC and EU were sterilized by ${\gamma}$-rays irradiation. Cytotoxicity of the mixture against HMC-1 cell was measured using cell counting kit-8 (CCK-8) assay. In addition, inflammatory mediator cytokines such as TNF-${\alpha}$, IL-6 and IL-8 were evaluated by ELISA kit on the HMC-1 cells with calcimycin A23187 and phorbol 12-myristate 13-acetate (PMA). The results showed that mixture of HC and EU had no cytoxicity and reduced TNF-${\alpha}$, IL-6, IL-8 response on HMC-1 cells.

• 방사선산업학회지
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• 제4권1호
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• pp.73-77
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• 2010

In recent day, there is much interest in the biocidal activity of silver since silver is known to be safe and effective as disinifectant and biocidal material against coliforms and viruses. In this study, hydrogels containing silver acetate as antibacterial agent have been prepared using gamma rays irradiation. The hydrogels are composed of poly(vinyl pyrrolidone) (PVP), poly(ethylene glycol) (PEG), carrageenan and silver acetate. The concentration of solution was 9 wt%. The ratio of PVP : PEG : carrageenan was 6 : 1 : 2. The concentration of the silver acetate were 0, 0.01, 0.03, 0.05 and 0.07% and Gamma irradiation dose was 25 kGy. The Gamma irradiation dose in hydrogels with 0.01% silver acetate were 20 kGy, 35 kGy, 50 kGy, 65 kGy, and 80 kGy. The results showed that 0.01% silver acetate concentration of hydrogels by 25 kGy irradiation dose showed the highest antibacterial activity against E. coli and Staphylococcus aureus. Moreover, antibacterial activity of various Gamma irradiation dose in hydrogels treated 0.01% silver acetate showed highest 35 kGy irradiation dose against Staphylococcus aureus.

• 방사선산업학회지
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• 제5권2호
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• pp.137-143
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• 2011

Epoxy resins are widely used as high performance thermosets in many industrial applications, such as coatings, adhesives and composites. Recently, a lot of research has been carried out in order to improve their mechanical properties and thermal stability in various fields. Carbon nanotubes possess high physical and mechanical properties that are considered to be ideal reinforcing materials in composites. CNT-reinforced epoxy system hold the promise of delivering superior composite materials with their high strength, light weight and multi functional features. Therefore, this study used multi-walled carbon nanotubes (MWNT) and gamma rays to improve the mechanical and thermal properties of epoxy. The diglycidyl ether of bisphenol A (DGEBA) as epoxy resins were cured by gamma ray irradiation with well-dispersed MWNTs as a reinforcing agent and triarylsulfonium hexafluoroantimonate (TASHFA) as an initiator. The flexural modulus was measured by UTM (universal testing machine). At this point, the flexural modulus factor exhibits an upper limit at 0.1 wt% MWNT. The thermal properties had improved by increasing the content of MWNT in the result of TGA (thermogravimetric analysis). However, they were decreased with increasing the radiation dose. The change of glass transition temperature by the radiation dose was characterized by DMA (dynamic mechanical analysis).

• Carbon letters
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• 제16권1호
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• pp.41-44
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• 2015

We report the preparation of sulfonated reduced graphene oxide (SRGO) by the sulfonation of graphene oxide followed by radiation-induced chemical reduction. Graphene oxide prepared by the well-known modified Hummer's method was sulfonated with the aryl diazonium salt of sulfanilic acid. Sulfonated graphene oxide (SGO) dispersed in ethanol was subsequently reduced by ${\gamma}$-ray irradiation at various absorbed doses to produce SRGO. The results of optical, chemical, and thermal analyses revealed that SRGO was successfully prepared by ${\gamma}$-ray irradiation-induced chemical reduction of the SGO suspension. Moreover, the electrical conductivity of SRGO was increased up to 2.94 S/cm with an increase of the absorbed dose.

• 폴리머
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• 제32권6호
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• pp.598-602
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• 2008

본 연구에서는 리튬이차전지용 상용 분리막에 전자선을 조사하여 가교구조를 지닌 내열성이 향상된 분리막을 제조하였고 조사선량에 의한 열적, 기계적 특성들을 평가하였다. 전자선 조사된 분리막의 열수축률은 조사선량이 증가할수록 감소하였고 AC impedance를 이용한 shutdown거동 연구 결과 전자선 조사를 하지 않은 분리막보다 우수한 shutdown 특성을 갖는 것으로 확인하였다. 또한, 전자선 조사선량이 증가할수록 분리막의 모듈러스는 향상되는 반면 인장강도와 파단 연신율은 감소됨이 관찰되었다.

• 방사선산업학회지
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• 제8권1호
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• pp.53-57
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• 2014

The kenaf is quickly developing as a renewable resource. Kenaf can be grown under a wide range of weather conditions. Modification of kenaf fiber by graft polymerization provides a significant route to alter the chemical properties, including surface hydrophilicity or hydrophobicity. In this study, kenaf fiber surfaces were grafted with acrylic acid as a hydrophilic group using electron beam irradiation. The grafting rate increased with an increase in grafting time. The FT-IR results confirmed that acrylic acid was successfully grafted onto the kenaf fibers. The wettability of the kenaf fiber was increased, accompanied by acylic acid grafting on the fiber surface. According to the permeability test result, it was found that acrylic acid grafted kenaf fiber reinforced cement composite was more reduced than non-grafted kenaf fiber reinforced cement composite.