Journal of Radiation Industry (방사선산업학회지)

Korean Society of Radiation Industry (한국방사선산업학회)
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Antibacterial Effect of PVP/PEG/Carrageenan/Silver Acetate Hydrogels by γ-ray

γ-ray를 이용하여 합성한 PVP/PEG/Carrageenan/Silver acetate 하이드로겔의 항균효과

  • Lim, Youn-Mook (Radiation Research Division for Industry & Environment, Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute) ;
  • Youn, Young (Radiation Research Division for Industry & Environment, Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute) ;
  • Gwon, Hui-Jeong (Radiation Research Division for Industry & Environment, Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute) ;
  • Park, Jong-Seok (Radiation Research Division for Industry & Environment, Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute) ;
  • Nho, Young-Chang (Radiation Research Division for Industry & Environment, Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute)
  • 임윤묵 (한국원자력연구원 방사선과학연구소 방사선공업환경연구부) ;
  • 윤영 (한국원자력연구원 방사선과학연구소 방사선공업환경연구부) ;
  • 권희정 (한국원자력연구원 방사선과학연구소 방사선공업환경연구부) ;
  • 박종석 (한국원자력연구원 방사선과학연구소 방사선공업환경연구부) ;
  • 노영창 (한국원자력연구원 방사선과학연구소 방사선공업환경연구부)
  • Received : 2010.03.07
  • Accepted : 2010.03.10
  • Published : 2010.03.30

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Abstract

In recent day, there is much interest in the biocidal activity of silver since silver is known to be safe and effective as disinifectant and biocidal material against coliforms and viruses. In this study, hydrogels containing silver acetate as antibacterial agent have been prepared using gamma rays irradiation. The hydrogels are composed of poly(vinyl pyrrolidone) (PVP), poly(ethylene glycol) (PEG), carrageenan and silver acetate. The concentration of solution was 9 wt%. The ratio of PVP : PEG : carrageenan was 6 : 1 : 2. The concentration of the silver acetate were 0, 0.01, 0.03, 0.05 and 0.07% and Gamma irradiation dose was 25 kGy. The Gamma irradiation dose in hydrogels with 0.01% silver acetate were 20 kGy, 35 kGy, 50 kGy, 65 kGy, and 80 kGy. The results showed that 0.01% silver acetate concentration of hydrogels by 25 kGy irradiation dose showed the highest antibacterial activity against E. coli and Staphylococcus aureus. Moreover, antibacterial activity of various Gamma irradiation dose in hydrogels treated 0.01% silver acetate showed highest 35 kGy irradiation dose against Staphylococcus aureus.

Keywords

Acknowledgement

Supported by : 한국과학재단