• Title/Summary/Keyword: Radiation Over-exposure

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DNA Damage of Lymphocytes in Volunteers after 4 hours Use of Mobile Phone (일부 자원자들의 이동전화 4시간 연속 사용 후 림프구 DNA 손상 평가)

  • Ji, Seon-Mi;Oh, Eun-Ha;Sul, Dong-Geun;Choi, Jae-Wook;Park, Hee-Chan;Lee, Eun-Il
    • Journal of Preventive Medicine and Public Health
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    • v.37 no.4
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    • pp.373-380
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    • 2004
  • Objectives : There has been gradually increasing concern about the adverse health effects of electromagnetic radiation originating from cell phones which are widely used in modern life. Cell phone radiation may affect human health by increasing free radicals of human blood cells. This study has been designed to identify DNA damage of blood cells by electromagnetic radiation caused by cell phone use. Methods : This study investigated the health effect of acute exposure to commercially available cell phones on certain parameters such as an indicator of DNA damage for 14 healthy adult volunteers. Each volunteer during the experiment talked over the cell phone with the keypad facing the right side of the face for 4 hours. The single cell gel electrophoresis assay (Comet assay), which is very sensitive in detecting the presence of DNA strand-breaks and alkali-labile damage in individual cells, was used to assess peripheral blood cells (T-cells, B-cells, granulocytes) from volunteers before and after exposure to cell phone radiation. The parameters of Comet assay measured were Olive Tail Moment and Tail DNA %. Results : The Olive Tail Moment of B-cells and granulocytes and Tail DNA % of B-cells and granulocytes were increased by a statistically significant extent after 4-hour use of a cell phone compared with controls. Conclusion : It is concluded that cell phone radiation caused the DNA damage during the 4 hours of experimental condition. Nonetheless, this study suggested that cell phone use may increase DNA damage by electromagnetic radiation and other contributing factors.

Search for the activity measurement of radionuclides I-131 (131I을 이용한 방사능 측정에 관한 연구)

  • Baek, Seong-Min;Jang, Eun-Sung
    • Journal of the Korean Society of Radiology
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    • v.6 no.1
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    • pp.79-82
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    • 2012
  • Iodine is one of important nuclides to be checked for radiation exposure after nuclear power facility accidents. After Chernobyl accident, it was observed that there is a greater amount of organic iodine in the atmosphere than inorganic iodine. In this study, we not only varied the amount of sample being exposed to $^{131}I$ and the duration of exposure to $^{131}I$ but also diluted the sample in distilled water and mixed the sample in kelp and liquid $^{131}I$ to measure and analyze the radiation detection levels. We concluded that the radiation levels were not high enough to be harmful to human body. The radiation from $^{131}I$ decreased over time, and we calculated the half life at 7-9 days. We found that the radiation from any sample containing $^{131}I$ was halved by up to 7days.

Projected lifetime cancer risk from cone-beam computed tomography for orthodontic treatment

  • Jha, Nayansi;Kim, Yoon-Ji;Lee, Youngjun;Lee, Ju Young;Lee, Won Jin;Sung, Sang-Jin
    • The korean journal of orthodontics
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    • v.51 no.3
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    • pp.189-198
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    • 2021
  • Objective: To estimate the projected cancer risk attributable to diagnostic cone-beam computed tomography (CBCT) performed under different exposure settings for orthodontic purposes in children and adults. Methods: We collected a list of CBCT machines and their specifications from 38 orthodontists. Organ doses were estimated using median and maximum exposure settings of 105 kVp/156.8 mAs and 130 kVp/200 mAs, respectively. The projected cancer risk attributable to CBCT procedures performed 1-3 times within 2 years was calculated for children (aged 5 and 10 years) and adult (aged 20, 30, and 40 years) male and female patients. Results: For maximum exposure settings, the mean lifetime fractional ratio (LFR) was 14.28% for children and 0.91% for adults; this indicated that the risk to children was 16 times the risk to adults. For median exposure settings, the mean LFR was 5.25% and 0.58% for children and adults, respectively. The risk of cancer decreased with increasing age. For both median and maximum exposure settings, females showed a higher risk of cancer than did males in all age groups. Cancer risk increased with an increase in the frequency of CBCT procedures within a given period. Conclusions: The projected dental CBCT-associated cancer risk spans over a wide range depending on the machine parameters and image acquisition settings. Children and female patients are at a higher risk of developing cancer associated with diagnostic CBCT. Therefore, the use of diagnostic CBCT should be justified, and protective measures should be taken to minimize the harmful biological effects of radiation.

A Study on the Exposure Parameter and the Patient Dose for Digital Radiography System in Dae Goo (디지털 방사선의학에서의 조사선량 설정과 인지에 대한 실태 - 대구 경북지역을 중심으로 -)

  • Jo, Gwang-Ho;Kang, Yeong-Han;Kim, Bu-Sun
    • Journal of radiological science and technology
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    • v.31 no.2
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    • pp.177-182
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    • 2008
  • Digital imaging for general rediography has many advantages over the film/screen systems, including a wider dynamic range and the ability to manipulate the images produced. The wider range means that acceptable images may by acquired at a range of dose levels, and therefore repeat exposures can be reduced. Digital imaging can result in the over use of radiation, however, because there is a tendency can be reduced. Digital imaging can result in the over use of radiation, however, because there is a tendency for images to be acquired at too high a dose. We investigated the actual exposure dose conditions on general radiography and a questionnaire survey was conducted with radiotechnologiest at medical institutions using digital radiology system. As a results, the dose of exposure was not controlled with patient's figure and dose optimization but was controlled by worker's convenience and image quality. Radio-technologiests often set up the exposure dose regardless of patient figure and body part to be examined. Many organizations, such as the International Commission on Radiological Protection, recommend to keep the dose as low as possible. In addition, they strongly recommend to keep the optimal but minimal dosage by proper training programs and constant quality control, including frequent patient dose evaluations and education.

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An Accidental over Exposure in Mednif Tele-Cobalt Machine in Nepal

  • chaurasia, P.P.;Srivastava, R.P.;Prasiko, G.;Neupane, B.P.
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2002.09a
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    • pp.97-99
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    • 2002
  • A radiation incident took place during treatment on MEDNIF Tele cobalt-60 therapy machine in B.P.KOIRALA MEMORIAL CANCER HOSPITAL in Bharatpur, Nepal. This Chinese made machine has activity of 6240 Curies of cobalt -60. This machine has fulfilled safety requirements. ICRP recommendations, safety rules are followed and practiced. The source was struck up during treatment and a technician was exposed to equivalent dose of 13.75 mSv. recorded by Personal film badge. Risks of workers are comparable to other safe industries. All exposures shall be kept as low as reasonably possible. The higher level of safety is achieved only when every one is dedicated to common goal. A lesson is learnt for future. Good practice is essential but not sufficient. A high demand for tele Cobalt therapy convinced management to replace Mednif machine with a new efficient Elite Tele Cobalt theratron Machine.

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The Radiobiological Evaluation on Abnormal Delivery of Cattle around Nuclear Power Plant using Micronucleus Assay in Lymphocyte (림프구 미소핵 측정법을 이용한 원자력발전소 주변 소의 이상산에 대한 방사선 생물학적 평가)

  • 김세라;김성호
    • Journal of Veterinary Clinics
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    • v.20 no.3
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    • pp.364-368
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    • 2003
  • Cytogenetic and hematological analysis was performed in peripheral blood from the cattle associated with abnormal delivery around nuclear power plant area. The frequency of micronuclei (MN) in peripheral blood lymphocytes from cattle was used as a biomarker of radiobiological effects resulting from exposure to environmental radiation. An estimated dose of radiation was calculated by best fitting linear-quadratic model based on the radiation-induced MN data over the range from 0 Gy to 4 Gy from the bovine lymphocytes with in vitro irradiation. MN rates in live malformed calf, dams of malformed calves and other cattle living in the same barn from the regions around nuclear power plant, and cattle in control area were 9/1000, 10.8/1000, 13.3/1000 and 10.0/1000, respectively. There were no significant differences in MN frequencies and hematological values between the cattle associated with abnormal delivery around nuclear power plant area and those of control area. This study indicates that the congenital abnormalities near nuclear power plant seemed to be caused by other aetiology.

Physiological and Biochemical Analyses of Rice Sensitivities to UVB Radiation

  • Hidema, Jun;Kumagai, Tadashi
    • Journal of Photoscience
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    • v.9 no.2
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    • pp.162-165
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    • 2002
  • Rice is widely cultivated in various regions throughout Asia. Over a five-year period, we investigated the effects of supplemental UVB radiation on the growth and yield of Japanese rice cultivars in the field. The findings of that study indicated that supplemental UVB radiation has inhibitory effects on the growth and grain development. Furthermore, we investigated the sensitivity to UVB radiation of rice cultivars of 5 Asian rice ecotypes, and found that rice cultivars vary widely in UVB sensitivity. The aim of our study is improving UVB resistance in plants by bioengineering or breeding programs. In order to make it, there is need to find the molecular origin of the sensitivity to UVB. Cyclobutane pyrimidine dimer (CPD) is major UV-induced DNA lesions. Plants possess two mechanisms to cope with such DNA damage. The first is the accumulation of UV-absorbing compounds. Our previous data showed that the steady-state CPD levels in leaves of rice grown under chronic radiation in any culture were not so greatly influenced by the increased UV-absorbing compounds content, although there was a significant positive correlation between the CPD levels induced by challenge UVB exposure and the UV-absorbing compounds content. The other is the repair of DNA damage. Photorepair is the major pathway in plants for repairing CPD. We found that the sensitivity to UVB could seriously correlate with the low ability in CPD photorepair in rice plants. These results suggest that photo lyase might be an excellent candidate for restoration by way of selective breeding or engineering in rice.

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Evaluation of Micronucleus Frequency in Cytokinesis-blocked Bovine Lymphocytes from Regions around Wolsong Nuclear Power Plant (세포질 분열 차단 림프구를 이용한 월성원자력발전소 주변 소의 미소핵 발생 평가)

  • Kim, Se-ra;Kim, Tae-hwan;Kim, Sung-ho
    • Korean Journal of Veterinary Research
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    • v.43 no.3
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    • pp.333-338
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    • 2003
  • Cytogenetic and hematological analysis was performed in bovine peripheral blood from the regions around Wolsong nuclear power plant and control area. The frequency of micronuclei (MN) in peripheral blood lymphocytes from cattle was used as a biomarker of radiobiological effects resulting from exposure to environmental radiation. An estimated dare of radiation was calculated by a best fitting linear-quadratic model based on the radiation-induced MN formation from the bovine lymphocytes exposed in vitro to radiation over the range from 0 Gy to 4 Gy. MN rates in lymphocytes of cattle from Wolsong nuclear power plant and control area were 9.87/1,000 and 9.60/1,000, respectively. There were no significant differences in MN frequencies and hematological values in cattle between Wolsong and control area. The study indicates that the MN assay is a rapid, sensitive and accurate method that can be used to monitor a large population exposed to radiation.

Research on Image Quality and Effective dose by Exposure Index Variation (Exposure Index변화에 따른 Image Quality와 Effective dose에 대한 연구: a Monte Carlo Simulation Study)

  • Kim, Hyun Soo;Jeong, Jae Ho;Lee, Jong Woong
    • Journal of the Korean Society of Radiology
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    • v.7 no.1
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    • pp.63-69
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    • 2013
  • Comparing with film-screen system, flat-panel detector has extensive dynamic range. Focusing flat-panel detector, whole body human phantom PBU-50 (Kyoto, kagaku, Japan) was used to perform comparative study of the estimate of image quality and exposure dose. the exposure condition was 81kV and 20mAs, which is used for Abdomen supine exam in clinical area. As a result of the kV change of the interpreted medical image which has over 30dB of PSNR value, the value of DAP shows the difference of 19.6 times. Moreover, the result of comparing kV change with effective dose of ICRP 103 shows that stochastic effect was increased by over exposure. Therefore, it is significantly necessary that digital radiation technical chart will be used to obtain high quality image and make the standard of dose by educating radio-technologist continually.

A CMOS Bandgap Reference Voltage Generator for a CMOS Active Pixel Sensor Imager

  • Kim, Kwang-Hyun;Cho, Gyu-Seong;Kim, Young-Hee
    • Transactions on Electrical and Electronic Materials
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    • v.5 no.2
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    • pp.71-75
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    • 2004
  • This paper proposes a new bandgap reference (BGR) circuit which takes advantage of a cascode current mirror biasing to reduce the V$\_$ref/ variation, and sizing technique, which utilizes two related ratio numbers k and N, to reduce the PNP BJT area. The proposed BGR is designed and fabricated on a test chip with a goal to provide a reference voltage to the 10 bit A/D(4-4-4 pipeline architecture) converter of the CMOS Active Pixel Sensor (APS) imager to be used in X-ray imaging. The basic temperature variation effect on V$\_$ref/ of the BGR has a maximum delta of 6 mV over the temperature range of 25$^{\circ}C$ to 70$^{\circ}C$. To verify that the proposed BGR has radiation hardness for the X-ray imaging application, total ionization dose (TID) effect under Co-60 exposure conditions has been evaluated. The measured V$\_$ref/ variation under the radiation condition has a maximum delta of 33 mV over the range of 0 krad to 100 krad. For the given voltage, temperature, and radiation, the BGR has been satisfied well within the requirement of the target 10 bit A/D converter.