• Title/Summary/Keyword: RN

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Effect of Mycelia Extracts from Lentinus edodes Mushroom-Cultured Lonicera japonica Thunberg on Anticancer and Antiallergy Activities (인동초로 배양한 표고버섯 균사체 추출물의 항암 및 알레르기 억제효과 검증)

  • Bae, Man-Jong;Ye, Eun-Ju
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.36 no.4
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    • pp.424-430
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    • 2007
  • This study was conducted to investigate the effect of mycelia of Lentinus edoes mushroom-cultured Lonicera japonica Thunberg (LLJ) on proliferation of the cancer cell lines (Hep3B, MCF-7 and HeLa), sarcoma 180 (S-180) and antiallergy. In an anti-cancer test using Hep3B (hepatic cancer cell), MCF-7 (breast cancer cell) and HeLa (uterine cancer cell), LLJ extract showed higher antiproliferating effect than that of LJ (Lonicera japonica Thunberg) extract. In an anti-cancer testing using Hep3B cells, LLJ extract showed growth-inhibitory effect of $85.60{\pm}4.66%$ at 3mg/rnL. In an anti-cancer testing using MCF-7 cells, LLJ and LJ extracts showed high antiproliferating effect. LLJ showed the tumor suppressive effect in mice injected with S-180 cells. The growth-inhibitory rates against tumor cells were 61% for LLJ, 37% for LJ. LLJ inhibited histamine release from rat peritoneal mast cells activated by compound 48/80. These results suggest that Lentinus edodes mushroom-cultured herb has an antiproliferating effect against cancer cell lines (Hep3B, MCF-7 and HeLa) and S-180 tumor, and will be beneficial in the treatment of allergic reaction.

Measurement of the Nursing Staff Needed for Two Specialized Nursing units in a University Hospital (간호업무량 측정 및 간호인력 수요산정)

  • 이윤신;박정호
    • Journal of Korean Academy of Nursing
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    • v.22 no.4
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    • pp.589-603
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    • 1992
  • This study investigated a process to estimate the need for nursing staff on the basis of a patient elassification system and the required care needs and activities. The investigation was carried out in the following four steps. Step 1. Patients were classified according to the amount of nursing care need on each shift as class I (mildly ill), class II (mederately ill), class III (acutely ill), and class IV (critically ill). Step 2. Measurement of the direct nursing care hours needed for each patient class, and measurement of indirect nursing care hourse and personal time of the nursing staff. Step 3. Calculation of he total nursing workload in a nursing unit. Step 4. Estimation of the nursing staff needed. The investigation was carried out from July 17th to 30th, during 24hours every other day. The subjects were the patients and the nursing staff on two units of Seoul National University Hospital, Korea. Some of the results from the investigation are as follows : 1) Distribution of patient classification On the neuro surgical (N.S.), the distribution was class I, 22 patient, 3, class II, 27 patients, class III, 26 patients, and class IV, 25 patients, For the orthopedic surgical unit(0.5.), it was class I, 43 patients, class II, 43 patients, class III, patients, and class IV, 3 patients. 2) Direct nursing care hours per day On the N.S. unit, 3.2 hours of direct nursing care were needed for class I, 3.9 hours for class II, 5.1 hours of class III, and 6.2 hours for class IV patients, while 2.0 hours for class I, 2.5 hours for class II, 3.5 hours for class III, 5.0 hours class IV patients were needed on the 0.5. units. 3) Analysis of direct nursing care activities Activities were classified into assessment and observation(47%), medication(38.7%), communiontion(5.1%), exercise(2.4%), elimination and irrigation(1.3%), treatmemt(1.1%), hygiene(0.8%), nutrition(0.8%), and hot and cold compress(0.1%). 4) Average hours of indirect nursing care per day. On the N.S. unit 4.2 hours, and on the O.S. unit, 3.5 hours of RN indirect care was needed. 5) The average personal time used by the of nursing staff was 17 minutes for both RNs and nursing assistants in the N.S. unit, and 32 minutes for both RNs and nursing assistants in the O.S. unit. 6) Estimation of nursing staff needed on two specialized units of a university hospital For the N.S. nursing unit of 43 beds, 31 nursing staff would be indicated. For the 0.5. nursing unit of the same number of beds, 19 nursing staff would be indicated.

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Design and Analysis of Intelligent AMC Scheme with Relay Protocols in LTE-Advanced System (LTE-Advanced 시스템에서 릴레이 프로토콜을 적용한 지능형 AMC 기법의 설계 및 분석)

  • Malik, Saransh;Kim, Bora;Moon, Sangmi;Kim, Daejin;Hwang, Intae
    • Journal of the Institute of Electronics and Information Engineers
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    • v.49 no.12
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    • pp.10-19
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    • 2012
  • In this paper, we propose an Adaptive Modulation and Coding (AMC) scheme using relay protocols generally known as Relay Node (RN). The AMC scheme is used for improving the throughput and a reliability of a communication system, because of the nature of different modulation and coding schemes. We analyze the performance of relay protocols with the AMC scheme and observed that relay protocols with the AMC scheme is capable of providing better average throughput at a lower Signal to Noise Ratio (SNR) level as compared to the conventional scheme with no AMC. We perform Monte Carlo simulations with Long Term Evolution-Advanced (LTE-A) parameters to prove the performance comparison of adaptive Modulation and Coding Scheme (MCS) relay protocols with the non-adaptive MCS relay protocols. The simulation results of the proposed system with adaptive MCS prove that among the Amplify-and-Forward (AF), Decode-and-Forward (DF) and DeModulate-and-Forward (DMF), the DMF protocol performs best at a lower SNR value and also provides better average throughput.

Verification of the Viability of Equipotential Switching Direct Current Potential Drop Method for Piping Wall Loss Monitoring with Signal Sensitivity Analysis (등전위 교번식 직류전위차법의 신호 정밀도 검증을 통한 배관 감육 진단 기술에의 적용성 검증)

  • Ryu, Kyung-Ha;Hwang, Il-Soon;Kim, Ji-Hyun
    • Journal of the Korean Society for Nondestructive Testing
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    • v.28 no.2
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    • pp.191-198
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    • 2008
  • Flow accelerated corrosion (FAC) phenomenon of low alloy carbon steels in nuclear power plant has been known as one of major degradation mechanisms. It has a potential to cause nuclear pipe rupture accident which may directly impact on the plant reliability and safety. Recently, the equipotential switching direct current potential drop (ES-DCPD) method has been developed, by the present authors, as a method to monitor wall loss in a piping. This method can rapidly monitor the thinning of piping, utilizing either the wide range monitoring (WiRM) or the narrow range monitoring (NaRM) technique. WiRM is a method to monitor wide range of straight piping, whereas NaRM focuses significantly on a narrow range such as an elbow. WiRM and NaRM can improve the reliability of the current FAC screening method that is based on computer modeling on fluid flow conditions. In this paper, the measurements by ES-DCPD are performed with signal sensitivity analyses in the laboratory environment for extended period and showed the viability of ES-DCPD for real plant applications.

Environmental Geochemistry of Radon at the Taejon City Area in Korea (대전시(大田市) 지역(地域) 라돈 환경(環境) 지화학(地化學) 연구(硏究))

  • Hong, Young-Kook
    • Economic and Environmental Geology
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    • v.30 no.1
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    • pp.51-60
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    • 1997
  • The high radon (Rn222) potentials of soil, groundwater, hotspring and indoor environments in the Taejon city area were delineated by use of an EDA RDA-200 radon detector. The U and Th contents were also analysed using a Multi Channel Analyzer to illustrate the sources of the radon potentials. The average U concentrations in Taejon vary according to the type of granites such as $4.14{\pm}2.36ppm$ in schistose granite (SG), $3.13{\pm}1.70ppm$ in biotite granite (BG) and $3.01{\pm}1.95ppm$ in two mica granite (TG). The U contents in the granites are closely related with the amounts of uraniferous minerals. However, the U contents in the soil are found to be $5.05{\pm}4.75ppm$ in TG, $4.07{\pm}1.69ppm$ in BG and $3.87{\pm}1.91ppm$ in SG which are mainly explained by the different cation exchange capacities (CEC) of the soils from various granites. The levels of soil radon are $552{\pm}656pCi/l$ in SG, in which levels at two locations exceed the level of 1,350 pCi/l established as guideline for follow-up action by the U.S. Environmental Protection Agency (EPA), $443{\pm}284pCi/l$ in TG and $224{\pm}115pCi/l$ in the BG. The soil radon concentrations are found to be proportional to the U content and hardness of the soils. The groundwater radon concentrations in the domestic wells of - 30~-100 m depth show that $6,907{\pm}4,665pCi/l$ in TG, $5,503{\pm}6,551pCi/l$ in SG and $2,104{\pm}1,157pCi/l$ in BG which are positively related with U contents in soils. The radon levels of six groundwater wells in TG and two in SG are greater than guideline for drinking water level, 10,000 pCi/l by EPA (1986). Average radon contents of hotsprings and public bathes in the TG area are $7,071{\pm}1,942pCi/l$ and $1,638{\pm}709pCi/l$, respectively, which are below the EPA standard for remedial action value of the 10,000 pCi/l. The mean indoor radon concentrations of the TG and SG areas are $1.60{\pm}1.20pCi/l$ and $1.60{\pm}0.70pCi/l$, respectively. The elevated indoor radon levels of 5.6 pCi/l and 6.7 pCi/l are found to be particularly in TG area, which exceeds 4 pCi/i guideline, correlating positively with the U contents in the soil and radon concentration in the groundwater.

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The Inflence of Excavation Damaged Zone around an Underground Research Tunnel in KAERI (한국원자력연구원 내 지하처분연구시설 주변의 암반 손상대 영향 평가)

  • Kwon, S.;Kim, J.S.;Cho, W.J.
    • Explosives and Blasting
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    • v.26 no.2
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    • pp.11-19
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    • 2008
  • The development of an excavation damaged zone, EDZ, due to the blasting impact and stress redistribution after excavation, can influence on the long tenn stability, economy, and safety of the underground excavation. In this study, the size and characteristics of an EDZ around an underground research tunnel, which was excavated by controlled blasting, in KAERI were investigated. The results were implemented into the modelling for evaluating the influence of an EDZ on hydro-mechanical behavior of the tunnel. From in situ tests at KURT, it was possible to determine that the size of EDZ was about l.5rn. Goodman jack tests and laboratory tests showed that the rock properties in the EDZ were changed about 50% compared to the rock properties before blasting. The size and property change in the EDZ were implemented to a hydro-mechanical coupling analysis. In the modeling, rock strengths and elastic modulus were assumed to be decreased 50% and. the hydraulic conductivity was increased 1 order. From the analysis, it was possible to see that the displacement was increased while the stress was decreased because of an EDZ. When an EDZ was considered in the model, the tunnel inflow was increased about 20% compared to the case without an EDZ.

Microarray Analysis of Gene Expression Profile by Treatment of Schizandrae fructus Extract in Inflammation-induced Human Epithelial A549 Cells (염증이 유발된 인간기관지상피세포에서 오미자가 Microarray를 이용한 유전자 발현 분석에 미치는 영향)

  • Jung, Jin-Yong;Jung, Sung-Ki;Jung, Hee-Jae;Rhee, Hyung-Koo
    • The Journal of Internal Korean Medicine
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    • v.29 no.3
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    • pp.543-553
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    • 2008
  • Objective: The goal of this study was to determine the anti-asthma mechanism of SF on TNF-${\alpha}$ induced activation on A549 (human type II-like epithelial) cells. Using oligonucleotide microarray, we sought to establish the molecular mechanism of the protective effects of SF on A549 cells. Material & Methods : Cells were cultured in three different conditions: 1) negative control group was cultured in normal condition of DMEM, 2) positive control group was activated with TNF-${\alpha}$, IL-4. and IL-1${\beta}$, and 3) SF treated group was previously treated with 0.1${\mu}g/ml$ SF after TNF-${\alpha}$, IL-4. and IL-1 activation. Cells of positive control and SF treated groups were cultured for 30 min, 1hr, 3hr and 6hr. Results : The comparative analysis of the gene expression profile revealed that proinflammatory cytokines such as IL1F8, IL1F9, IL1R1. IL1RN, IL1RAPL1, IL8, TNFRSF4, TNFSF10c, TNFSF13, TRAF5, and TRAF7 and inflammation-related genes including MMP2, MMP11, MMP14, MMP15, MMP16, MMP19, MMP25, and MMP27 were down regulated with SF treatment. Cell adhesion molecule genes such as ITGB1, ITGBL1, selectin P ligand, selectin E, ICAM2, ICAM3, VCAM1, PECAM, FCER1G and MMP28 genes were also down-regulated in SF treated A549 cells. Conclusion : These results suggest that the anti-asthmatic effects of SF could be mediated by regulating specific genes related with cell adhesion, proinflammatory cytokine and inflammation-related genes in A549 cells.

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An Analysis of Primary Causes for Waiting for Inpatient Admission and Length of stay at Emergency Medical Center(EMC) (응급의료 센터의 체류 및 입원대기 시간 지연 요인 - 일개 의료기관을 중심으로 -)

  • Kil Suk-Yong;Kim Ok-Jun;Park Jin-Sun
    • Journal of Korean Academy of Fundamentals of Nursing
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    • v.6 no.3
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    • pp.522-531
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    • 1999
  • This research identifies the ingress to egress primary factors that causes a patient to receive delayed emergency medical care. This material was collected between February 1st to 28th, 1998. Research envolved 4,118 people who visited the college emergency medical center in Kyeongido Province, South Korea. Medical records were examined, using the retrospective method. to determine the length of stay and the main cause for waiting. Results are as follows : 1. The age group with the highest admission rate was 10 and under, approximately 1,394 (33.9%). Followed by an even distribution for ages between 11-50 at 10-15% for their respective ranges. The lowest admission rate was 50 years and above. 2. From the 4,118 records examined, 3,489 received outpatient treatment (84.7%); 601 were admitted for inpatient care (14.6%); 25 arrived dead on arrival (0.6%); and 4 people died at the hospital. 3. Between 7PM to 12AM, 42.9% were admitted to the EMC. The hours from 9PM to 11PM recorded the highest admission rate and 5AM to 8AM was the lowest From 8PM to 12AM, the most beds were occupied. 4. For most patients. the average length of stay was approximately 2.2 hours. By medical department, external medicine was the longest for 2.8 hours. Pediatrics was the shortest for 1.6 hours. The average waiting period for inpatient admission was 2.6 hours. Inpatient admission for pediatrics and external medicine was 3.4 hours and 2.2 hours respectively. 5. Theses are primary factors for delay at EMC: 1) pronged medical consultations to decide between inpatient versus outpatient treatment, and delaying to be inpatient, 2) when you call physicians they are delayed to come 3) Understaffing during peak or critical hours, 4) Excessive consulting with different medical departments, 5) some patients require longer monitoring periods, 6) medical records are delayed in transit between departments, 7) repeated laboratory tests make delay the result, 8) overcrowded emergency x-ray place causes delay taking x-ray and portable x-ray, 9) the distance between EMC and registration and cashier offices is too far. 10) hard to control patient's family members. The best way to reduce EMC waiting and staying time is by cooperation between departments, both medical and administrative. Each department must work beyond their job description or duty and help each other to provide the best medical service and satisfy the patient needs. The most important answer to shortened the EMC point from ingress to egress is to see things from a patient point of view and begin from there to find the solution.

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An Investigational Study of Nursing College Student's Clinical Practice Satisfaction (3년제 간호대학생의 임상실습 만족도에 관한 조사 연구)

  • Kim, Eun-Ha;Oh, Yoon-Hee
    • The Journal of Korean Academic Society of Nursing Education
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    • v.6 no.2
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    • pp.186-198
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    • 2000
  • The purpose of this study was to investigate the factors and the degree of nursing college student's clinical practice satisfaction. The sample consisted of 488 nursing students who had been in the clinical practice experience from 6 junior nursing colleges in Korea. Data for this study was collected from 20 May to 20 June, 2000. Data were analysed by SPSS/PC using frequency, percentage, mean, standard deviation, T-test, one-way ANOVA, and regression. The results of this study are as follows : 1. The highest motive of selecting a nursing science came to be 'having a good prospect for getting a job' (29.3%), major place of the clinical nursing practice was university hospital(46.5%), and the degree of satisfaction about the nursing science was 'relatively satisfied' (43%). 2.The fields that the highest satisfaction of the nursing student's clinical practice were DR(3.25), NR(3.18), ICU(3.11), and OR(3.10). The highest rank of the nursing student's clinical practice satisfaction was 'feels more continuous nursing studying is required after getting a job or pass the RN exam'(4.24). 3. There was significant value between the Grade(2yr, 3yr) and the satisfaction of the clinical practice environment(p<0.001), the clinical practice interpersonal relationship (p<0.001), the clinical practice evaluation (p<0.05), and there was significant value between the satisfaction about the nursing science and the satisfaction of the clinical practice environment(p<0.001), the clinical practice interpersonal relation ship (p<0.05), the satisfation after the clinical practice(p<0.001). 4. There was significant value between 'the opinion of the clinical practice periods' and the satisfaction of the clinical practice place(p<0.05), the clinical practice environment(p<0.001), the clinical practice interpersonal relationship(p<0.001), the satisfation after the clinical practice(p<0.001). 5.The satisfaction of the clinical practice interpersonal relationship influenced on the nursing student's clinical practice satisfaction($R^{2}=.188$). From these results, it is suggested that the higher the satisfaction of the clinical practice interpersonal relationship be like to improve the nursing college student's clinical practice satisfaction.

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A Study on the Seasonal Comparison of Dry Matter Intake, Digestibility, Nitrogen Balance and Feeding Behavior in Spotted Deer (Cervus nippon) Fed Forest By-products Silage and Corn Silage

  • Moon, S.H.;Jeon, B.T.;Kang, S.K.;Sung, S.H.;Hudson, R.J.
    • Asian-Australasian Journal of Animal Sciences
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    • v.17 no.1
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    • pp.80-85
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    • 2004
  • The purpose of this experiment was to assess seasonal variation of feed utilization by feed sources and to obtain information on the use of feed resources by comparing seasonal changes of dry matter intake, digestibility, nitrogen balance and feeding behavior in spotted deer (Cervus nippon) fed forest by-product silage (FBS) and corn silage (CS). Dry matter intake (DMI) of FBS was higher than that of CS in both winter and summer. While DMI of both diets was higher in summer, this was not significant at the 5% level. In contrast to DMI, digestible dry matter intake (DDMI) was higher for CS than for FBS in both seasons, but the difference was not significant. Digestibility of dry matter and crude protein was significantly higher (p<0.01) for CS than for FBS, whereas digestibility of crude fiber was significantly higher (p<0.01) for FBS than for CS in both seasons. Seasonal digestibility of dry matter and crude fiber for FBS was significantly greater (p<0.01) in summer than in winter: In summer, seasonal digestibility was 57.2% for dry matter and 55.5% for crude fiber, and in winter, 50.8% for dry matter and 30.7% for crude fiber. On the other hand, seasonal digestibility of crude protein was higher (p<0.01) in winter (42.1%) than in summer (32.3%). No significant difference (p>0.05) was found between the two seasons and diets for nitrogen intake (NI), 18.7 g/d in summer and 19.4 g/d in winter for FBS, 17.7 g/d in summer and 17.7 g/d in winter for CS. Fecal nitrogen was higher (p<0.01) for FBS than for CS and varied little seasonally. There was significant difference (p<0.01) between two seasons in urinary nitrogen, which was little difference between two diets. Retained nitrogen (RN) was different significantly (p<0.01) between two diets in both seasons, but there was little difference between seasons. Deer usually spent longer time on eating FBS than eating CS. Eating FBS took 221 min in summer and 187 min in winter, whereas eating CS took 113 min in summer and 109 min in winter. Deer spent less time on eating food in winter than in summer. Time spent on rumination was longer for FBS than for CS: for FBS, 504 min in summer and 456 min in winter, for CS, 423 min in summer and 279 min in winter. Time varied seasonally with both diets.