• Asian Pacific Journal of Cancer Prevention
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• v.13 no.2
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• pp.621-623
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• 2012

To estimate the genetic susceptibility for childhood lymphoma, we conducted an association study for 23 cases and 148 controls. Total 1536 tag single nucleotide polymorphisms (SNPs) were selected in 138 candidate gene regions related to immune responses, apoptosis, the cell cycle, and DNA repair. Twelve SNPs were significantly associated with the risk of lymphoma ($P_{trend}$ <0.05) in six genes ($IL1RN$, $IL2$, $IL12RB1$, $JAK3$, $TNFRSF13B$, and $XRCC3$). The most significant association was seen for $IL2$ variant rs2069762 ($OR_{TG+GG}$ vs. TT=3.43 (1.29-9.11), $P_{trend}$=0.002, min$P$=0.005). These findings suggest that common genetic variants in $IL2$ might play a role in the pathogenesis of childhood lymphoma.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.30 no.6
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• pp.356-360
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• 2017

We investigated the phase evolution, microstructure, and microwave dielectric properties of Na- and Zr-doped $Ba(Mg_{0.5}W_{0.5})O_3$ [i.e., ($Ba_{1-2x}Na_{2x})(Mg_{0.5-x}Zr_xW_{0.5})O_3$] ceramics. $BaWO_4$ as a secondary phase was observed in all compositions, and it increased as the dopant concentration increased. All specimens revealed a dense microstructure. For the composition of x=0.01, polyhedral grains were observed. As the dopant concentration increased, the densification and the grain growth were promoted by a liquid phase. The quality factor($Q{\times}f_0$) decreased remarkably, whereas the dielectric constant (${\varepsilon}_r$) tended to decrease as the dopant concentration increased. The dielectric constant, quality factor, and temperature coefficient of the resonant frequency of the composition of x=0.01 sintered at $1,700^{\circ}C$ for 1 h were 18.6, 216,275 GHz, and $-22.0ppm/^{\circ}C$, respectively.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.12 no.4
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• pp.1638-1654
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• 2018

The heterogeneous network (HetNet) has been one of the key technologies in Long Term Evolution-Advanced (LTE-A) with growing capacity and coverage demands. However, the introduction of femtocells has brought serious co-layer interference and cross-layer interference, which has been a major factor affecting system throughput. It is generally acknowledged that the resource allocation has significant impact on suppressing interference and improving the system performance. In this paper, we propose a hybrid-clustering algorithm based on the $Mat{\acute{e}}rn$ hard-core process (MHP) to restrain two kinds of co-channel interference in the HetNet. As the impracticality of the hexagonal grid model and the homogeneous Poisson point process model whose points distribute completely randomly to establish the system model. The HetNet model based on the MHP is adopted to satisfy the negative correlation distribution of base stations in this paper. Base on the system model, the spectrum sharing problem with restricted spectrum resources is further analyzed. On the basis of location information and the interference relation of base stations, a hybrid clustering method, which takes into accounts the fairness of two types of base stations is firstly proposed. Then, auction mechanism is discussed to achieve the spectrum sharing inside each cluster, avoiding the spectrum resource waste. Through combining the clustering theory and auction mechanism, the proposed novel algorithm can be applied to restrain the cross-layer interference and co-layer interference of HetNet, which has a high density of base stations. Simulation results show that spectral efficiency and system throughput increase to a certain degree.

• Journal of Korean Academy of Nursing
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• v.27 no.4
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• pp.880-891
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• 1997

The purpose of this study was (1)to undertake a survey to identify the profile of inactive nurses, who account for 42.2% of the 130,000 RN(Registered Nurses) in Korea, (2)to identify factors related to the inactivation of these nurses, (3)to identify reasons behind the high turnover rate of nurses, and (4)to delineate measures for inactive nurses to participate in professional nursing activities so as to upgrade the quality of the health care delivery system in Korea. For these purposes, this study surveyed existing literature on the turnover of nurses and, used the nominal group technique of action research, to collect ideas from hospital/nurse administrators, inactive nurses, nurses on the job, graduate students in nursing, part-time nurses, patients, and their families to formulate strategies to mobilize inactive nurses. The findings are as follows : Frist, institutional supports should be provided to mobilize inactive nurses. To be more specific : (1) A data-base needs be created at the Korean Nurses Association to link inactive nurses with jobs available. (2) Retraining programs need be established to equip inactive nurses for new jobs. (3) Comprehensive information related to employment needs should be made available. Second, a conducive environment needs to be created to draw in inactive nurses to the job market. To be more specific : (1) A system of part-time work needs to be introduced in hospitals. (2) Nurse-specialists need to be promoted. (3) Potential jobs need to be created. (4) Working environment and terms and conditions for nurses need to be improved. (5) Competent nurses need to be secured in the health care delivery system. To achieve the goals presented above, this paper presented 55 specific strategies that may help mitigate the turnover rate of nurses and, in turn, help make the Korean Nurses Association effective in implementing its policies.

• Journal of Korean Academy of Nursing
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• v.27 no.4
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• pp.871-879
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• 1997

인간은 사회적 접촉을 필요로 하고 타인과의 상호작용을 원하는 사회적 동물이다. 외로움은 한 개인의 사회적 관계의 망이 양적이나 질적으로 부족할 때 발생하는 불유쾌한 감정이다. 외로움은 매우 보편적인 감정이나 고통스러울 수 있으며 이러한 경험이 지속되면 정신적, 신체적 건강을 해칠 수 있을 뿐 아니라 자살을 초래하기도 한다. 특히 노인은 여러 가지 종류의 변화와 상실을 경험하기 때문에 외로움을 더 느낄 수 있다. 본 연구의 목적은 번역과 역번역 과정을 통해 Revised UCLA Loneliness Scale에 대한 한국어 UCLA 외로움 사정도구를 만들고 이 도구를 한국노인에게 적용하여 신뢰도와 타당도를 조사하는 것이다. 개정판UCLA외로움 사정 도구는 각각 3번씩의 번역과 역번역 과정을 통해 원본 영문도구와 역번역된 영문도구 사이에 의미의 차이가 없다고 판단될 때까지 만들어졌다. 번역과 역번역 과정은 미국에서 석사나 박사학위를 취득한 6명의 한국유학생들에 의해 이루어 졌으며 원본 영문도구와 역번역된 도구사이의 의미의 차이는 본 저자와 미국인 간호학 교수에 의해 사정되었다. 번역된 한국어 외로움 사정도구는 미국의 3개 주에 거주하는 203명의 한국노인들을 대상으로 신뢰도와 타당도 조사가 이루어졌다. 한국어 UCLA외로움 사정도구의 신뢰계수는 .93으로 한국어 도구의 내용이 전반적으로 동질성을 띈다는 것을 알 수 있었다. 이는 Barren등(1992)이 미국인 노인여성을 대상으로 한 연구에서 얻은 신뢰계수 .87보다 높은 것이었다. 한국어 도구의 구성타당도를 조사하기 위해 요인 분석을 실시한 결과 본 도구는 친밀한 주변인, 사회적 주변인, 및 소속감 등의 3개 요인을 가지는 것으로 분석되었다. 구성타당도에 대한 이러한 결과는 미국의 대학생들을 대상으로 한 Austin(1983)의 연구결과와 일치하는 것이었다. 각 요인에 대한 신뢰계수는 .88(제 1요인), .90(제 2요인), .84(제 3요인)로 나타났다. 전반적으로 대상자들은 한국어 도구에 대해 이해를 잘 하는 편이었으나 부정문인 4번 항목, '나는 혼자라고 느끼지 않는다'에 대해서는 응답을 할 때는 다른 항목에 비해 시간이 더 소요되거나 연구보조자에 의한 반복 설명이 필요하기도 하였다.