• 한국식품영양과학회지
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• 제36권4호
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• pp.424-430
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• 2007

인동초를 이용하여 표고균사체를 접종, 배양하여 얻어진 인동초균사체 추출액의 간암세포, 유방암세포, 자궁경부암세포 그리고 고형암의 증식에 미치는 영향을 조사하였다. 3가지 암세포의 형태변화 및 증식 억제에 미치는 영향에서 간암세포와 유방암세포에서 암세포에 대한 특이적 형태변화가 관찰되었고, 특히 간암세포에서 인동초균사체 추출물이 인동초추출물보다 효과적인 것으로 나타났다. 인동초균사체를 간암세포에 3mg/mL로 처리했을 때 $85.60{\pm}4.66%$의 암세포 증식억제율을 나타내어 인동초를 처리한 것보다 암세포 증식 억제율이 61.10% 높았다. 유방암세포에서는 인동초 및 인동초균사체를 처리한 것 모두 높은 암세포 증식억제율을 보였으며, 두 군간의 차이는 미미한 것으로 나타났다. 자궁경부암세포에서는 인동초 및 인동초균사체를 처리한 것 모두 암세포 증식억제율이 미미한 것으로 나타났다. 고형암 억제효과에서는 대조군에 비해 인동초균사체 추출물에서 고형암이 61% 억제되었으며, 인동초균사체가 인동초추출물보다 고형암 억제효과가 30% 더 높은 것으로 나타났다. 히스타민 유리 억제효과를 측정한 결과 compound 48/80처리군에 비해 인동초추출물은 9.07%, 인동초균사체 추출물은 43.05%의 히스타민 분비 억제효과가 있는 것으로 나타났다.

• 대한간호학회지
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• 제22권4호
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• pp.589-603
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• 1992

This study investigated a process to estimate the need for nursing staff on the basis of a patient elassification system and the required care needs and activities. The investigation was carried out in the following four steps. Step 1. Patients were classified according to the amount of nursing care need on each shift as class I (mildly ill), class II (mederately ill), class III (acutely ill), and class IV (critically ill). Step 2. Measurement of the direct nursing care hours needed for each patient class, and measurement of indirect nursing care hourse and personal time of the nursing staff. Step 3. Calculation of he total nursing workload in a nursing unit. Step 4. Estimation of the nursing staff needed. The investigation was carried out from July 17th to 30th, during 24hours every other day. The subjects were the patients and the nursing staff on two units of Seoul National University Hospital, Korea. Some of the results from the investigation are as follows : 1) Distribution of patient classification On the neuro surgical (N.S.), the distribution was class I, 22 patient, 3, class II, 27 patients, class III, 26 patients, and class IV, 25 patients, For the orthopedic surgical unit(0.5.), it was class I, 43 patients, class II, 43 patients, class III, patients, and class IV, 3 patients. 2) Direct nursing care hours per day On the N.S. unit, 3.2 hours of direct nursing care were needed for class I, 3.9 hours for class II, 5.1 hours of class III, and 6.2 hours for class IV patients, while 2.0 hours for class I, 2.5 hours for class II, 3.5 hours for class III, 5.0 hours class IV patients were needed on the 0.5. units. 3) Analysis of direct nursing care activities Activities were classified into assessment and observation(47%), medication(38.7%), communiontion(5.1%), exercise(2.4%), elimination and irrigation(1.3%), treatmemt(1.1%), hygiene(0.8%), nutrition(0.8%), and hot and cold compress(0.1%). 4) Average hours of indirect nursing care per day. On the N.S. unit 4.2 hours, and on the O.S. unit, 3.5 hours of RN indirect care was needed. 5) The average personal time used by the of nursing staff was 17 minutes for both RNs and nursing assistants in the N.S. unit, and 32 minutes for both RNs and nursing assistants in the O.S. unit. 6) Estimation of nursing staff needed on two specialized units of a university hospital For the N.S. nursing unit of 43 beds, 31 nursing staff would be indicated. For the 0.5. nursing unit of the same number of beds, 19 nursing staff would be indicated.

• 전자공학회논문지
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• 제49권12호
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• pp.10-19
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• 2012

본 논문에서는 AMC(Adaptive Modulation and Coding) 기법을 적용한 릴레이 프로토콜을 제안한다. AMC 기법은 다양한 변조와 코딩 기법을 통해, 통신 시스템의 전송률과 신뢰도를 향상시킬 수 있다. 본 논문에서는 AMC 기법을 적용한 릴레이 프로토콜의 성능을 분석하고, AMC 기법이 적용된 릴레이 프로토콜이 AMC 기법이 적용되지 않은 기존의 기법과 비교하여 낮은 SNR(Signal to Noise Ratio) 레벨에서 더 좋은 평균 전송률을 제공할 수 있음을 확인하였다. 비적응적 MCS(Modulation and Coding Scheme) 릴레이 프로토콜과 적응적 MCS 릴레이 프로토콜의 성능을 증명하기 위해 LTE-A(Long Term Evolution-Advanced) 파라미터와 함께 몬테카를로 시뮬레이션을 수행하였다. 모의실험 결과, 적응적 MCS가 적용된 시스템에서 AF(Amplify-and-Forward), DF(Decode-and-Forward) 및 DMF(DeModulate-and-Forward) 프로토콜 중 DMF 프로토콜이 낮은 SNR 값에서 가장 좋은 성능을 보이고, 더 좋은 평균 전송률을 제공하는 것을 확인하였다.

• 비파괴검사학회지
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• 제28권2호
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• pp.191-198
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• 2008

유체가속부식에 의한 탄소강 배관의 감육은 원자력 발전소 저탄소강 배관의 주요 경년열화 현상으로서, 예상치 못한 배관의 파단을 야기해 발전소의 성능 및 안전을 저해할 수 있다. 최근, 등전위 교번식 직류 전위차법(ES-DCPD, equipotential switching direct current potential drop)을 이용한 배관 감육의 정밀 감시기법이 본 연구자들에 의하여 개발되었다. ES-DCPD 방법은 넓은 배관 영역을 빠르게 검사할 수 있는 방법으로, 넓은 영역의 직관부 감육을 빠르게 검사하는 광역감시법(WiRN, wide range monitoring)과 엘보우 등 곡관부의 감육이 활발한 컴포넌트의 국부적 감육을 비교적 넓은 범위에서 빠르게 스캔하는 협역감시법(NaRM, narrow range monitoring)으로 사용이 가능하다. 광역감시와 협역감시 기법은 초음파검사의 위치 선정파 초음파검사의 검사 누락부에 대한 신뢰성을 개선할 수 있을 것이다. 본 논문에서는 ES-DCPD를 바탕으로 한 새로운 감육 진단 기술을 실험실 환경에서 장기 검증 시험을 수행하여 신호 정밀도를 분석하였고, 결과의 현장 적용성을 논의하였다.

• 자원환경지질
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• 제30권1호
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• pp.51-60
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• 1997

The high radon (Rn222) potentials of soil, groundwater, hotspring and indoor environments in the Taejon city area were delineated by use of an EDA RDA-200 radon detector. The U and Th contents were also analysed using a Multi Channel Analyzer to illustrate the sources of the radon potentials. The average U concentrations in Taejon vary according to the type of granites such as $4.14{\pm}2.36ppm$ in schistose granite (SG), $3.13{\pm}1.70ppm$ in biotite granite (BG) and $3.01{\pm}1.95ppm$ in two mica granite (TG). The U contents in the granites are closely related with the amounts of uraniferous minerals. However, the U contents in the soil are found to be $5.05{\pm}4.75ppm$ in TG, $4.07{\pm}1.69ppm$ in BG and $3.87{\pm}1.91ppm$ in SG which are mainly explained by the different cation exchange capacities (CEC) of the soils from various granites. The levels of soil radon are $552{\pm}656pCi/l$ in SG, in which levels at two locations exceed the level of 1,350 pCi/l established as guideline for follow-up action by the U.S. Environmental Protection Agency (EPA), $443{\pm}284pCi/l$ in TG and $224{\pm}115pCi/l$ in the BG. The soil radon concentrations are found to be proportional to the U content and hardness of the soils. The groundwater radon concentrations in the domestic wells of - 30~-100 m depth show that $6,907{\pm}4,665pCi/l$ in TG, $5,503{\pm}6,551pCi/l$ in SG and $2,104{\pm}1,157pCi/l$ in BG which are positively related with U contents in soils. The radon levels of six groundwater wells in TG and two in SG are greater than guideline for drinking water level, 10,000 pCi/l by EPA (1986). Average radon contents of hotsprings and public bathes in the TG area are $7,071{\pm}1,942pCi/l$ and $1,638{\pm}709pCi/l$, respectively, which are below the EPA standard for remedial action value of the 10,000 pCi/l. The mean indoor radon concentrations of the TG and SG areas are $1.60{\pm}1.20pCi/l$ and $1.60{\pm}0.70pCi/l$, respectively. The elevated indoor radon levels of 5.6 pCi/l and 6.7 pCi/l are found to be particularly in TG area, which exceeds 4 pCi/i guideline, correlating positively with the U contents in the soil and radon concentration in the groundwater.

• 화약ㆍ발파
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• 제26권2호
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• pp.11-19
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• 2008

지하구조물의 굴착을 위한 발파 충격과 굴착후 응력의 재분포에 의해 발생하는 암반 손상대(Excavation Damaged Zone, EDZ)의 발생은 구조물의 장기적 안정성 경제성 안전성에 영향을 미친다. 본 연구에서는 조절발파기법으로 굴착된 한국원자력연구원 내 지하처분연구시설에서 굴착 후 발생하는 손상대 규모 및 특성을 측정, 분석하였으며 이를 모델링에 적용하여 손상대가 터널의 역학적, 수리적 거동에 미치는 영향을 평가하고자 하였다. KURT에서의 손상대 현장시험을 통해 1.5m의 손상구간을 확인할 수 있었으며 Goodman jack 시험과 실험실 암석실험을 통해 암반의 물성은 발파전 물성에 비해 대체적으로 50% 정도 변화함을 알 수 있었다. 이러한 암반 손상대 크기와 물성변화를 모델링에 적용하여 수리-역학적 연동해석을 실시하였다. 손상받지 않은 구간에 비해 손상대의 변형계수는 50%감소하며 수리전도도는 1 order증가하는 것으로 가정하였다. 해석 결과 손싱대를 고려하는 경우 변위는 증가하고 응력은 감소하며 지하수 유입량은 약 20% 정도 증가하는 것으로 나타났다.

• 대한한방내과학회지
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• 제29권3호
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• pp.543-553
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• 2008

Objective: The goal of this study was to determine the anti-asthma mechanism of SF on TNF-${\alpha}$ induced activation on A549 (human type II-like epithelial) cells. Using oligonucleotide microarray, we sought to establish the molecular mechanism of the protective effects of SF on A549 cells. Material & Methods : Cells were cultured in three different conditions: 1) negative control group was cultured in normal condition of DMEM, 2) positive control group was activated with TNF-${\alpha}$, IL-4. and IL-1${\beta}$, and 3) SF treated group was previously treated with 0.1${\mu}g/ml$ SF after TNF-${\alpha}$, IL-4. and IL-1 activation. Cells of positive control and SF treated groups were cultured for 30 min, 1hr, 3hr and 6hr. Results : The comparative analysis of the gene expression profile revealed that proinflammatory cytokines such as IL1F8, IL1F9, IL1R1. IL1RN, IL1RAPL1, IL8, TNFRSF4, TNFSF10c, TNFSF13, TRAF5, and TRAF7 and inflammation-related genes including MMP2, MMP11, MMP14, MMP15, MMP16, MMP19, MMP25, and MMP27 were down regulated with SF treatment. Cell adhesion molecule genes such as ITGB1, ITGBL1, selectin P ligand, selectin E, ICAM2, ICAM3, VCAM1, PECAM, FCER1G and MMP28 genes were also down-regulated in SF treated A549 cells. Conclusion : These results suggest that the anti-asthmatic effects of SF could be mediated by regulating specific genes related with cell adhesion, proinflammatory cytokine and inflammation-related genes in A549 cells.

• 기본간호학회지
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• 제6권3호
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• pp.522-531
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• 1999

This research identifies the ingress to egress primary factors that causes a patient to receive delayed emergency medical care. This material was collected between February 1st to 28th, 1998. Research envolved 4,118 people who visited the college emergency medical center in Kyeongido Province, South Korea. Medical records were examined, using the retrospective method. to determine the length of stay and the main cause for waiting. Results are as follows : 1. The age group with the highest admission rate was 10 and under, approximately 1,394 (33.9%). Followed by an even distribution for ages between 11-50 at 10-15% for their respective ranges. The lowest admission rate was 50 years and above. 2. From the 4,118 records examined, 3,489 received outpatient treatment (84.7%); 601 were admitted for inpatient care (14.6%); 25 arrived dead on arrival (0.6%); and 4 people died at the hospital. 3. Between 7PM to 12AM, 42.9% were admitted to the EMC. The hours from 9PM to 11PM recorded the highest admission rate and 5AM to 8AM was the lowest From 8PM to 12AM, the most beds were occupied. 4. For most patients. the average length of stay was approximately 2.2 hours. By medical department, external medicine was the longest for 2.8 hours. Pediatrics was the shortest for 1.6 hours. The average waiting period for inpatient admission was 2.6 hours. Inpatient admission for pediatrics and external medicine was 3.4 hours and 2.2 hours respectively. 5. Theses are primary factors for delay at EMC: 1) pronged medical consultations to decide between inpatient versus outpatient treatment, and delaying to be inpatient, 2) when you call physicians they are delayed to come 3) Understaffing during peak or critical hours, 4) Excessive consulting with different medical departments, 5) some patients require longer monitoring periods, 6) medical records are delayed in transit between departments, 7) repeated laboratory tests make delay the result, 8) overcrowded emergency x-ray place causes delay taking x-ray and portable x-ray, 9) the distance between EMC and registration and cashier offices is too far. 10) hard to control patient's family members. The best way to reduce EMC waiting and staying time is by cooperation between departments, both medical and administrative. Each department must work beyond their job description or duty and help each other to provide the best medical service and satisfy the patient needs. The most important answer to shortened the EMC point from ingress to egress is to see things from a patient point of view and begin from there to find the solution.

• 한국간호교육학회지
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• 제6권2호
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• pp.186-198
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• 2000

The purpose of this study was to investigate the factors and the degree of nursing college student's clinical practice satisfaction. The sample consisted of 488 nursing students who had been in the clinical practice experience from 6 junior nursing colleges in Korea. Data for this study was collected from 20 May to 20 June, 2000. Data were analysed by SPSS/PC using frequency, percentage, mean, standard deviation, T-test, one-way ANOVA, and regression. The results of this study are as follows : 1. The highest motive of selecting a nursing science came to be 'having a good prospect for getting a job' (29.3%), major place of the clinical nursing practice was university hospital(46.5%), and the degree of satisfaction about the nursing science was 'relatively satisfied' (43%). 2.The fields that the highest satisfaction of the nursing student's clinical practice were DR(3.25), NR(3.18), ICU(3.11), and OR(3.10). The highest rank of the nursing student's clinical practice satisfaction was 'feels more continuous nursing studying is required after getting a job or pass the RN exam'(4.24). 3. There was significant value between the Grade(2yr, 3yr) and the satisfaction of the clinical practice environment(p<0.001), the clinical practice interpersonal relationship (p<0.001), the clinical practice evaluation (p<0.05), and there was significant value between the satisfaction about the nursing science and the satisfaction of the clinical practice environment(p<0.001), the clinical practice interpersonal relation ship (p<0.05), the satisfation after the clinical practice(p<0.001). 4. There was significant value between 'the opinion of the clinical practice periods' and the satisfaction of the clinical practice place(p<0.05), the clinical practice environment(p<0.001), the clinical practice interpersonal relationship(p<0.001), the satisfation after the clinical practice(p<0.001). 5.The satisfaction of the clinical practice interpersonal relationship influenced on the nursing student's clinical practice satisfaction($R^{2}=.188$). From these results, it is suggested that the higher the satisfaction of the clinical practice interpersonal relationship be like to improve the nursing college student's clinical practice satisfaction.

• Asian-Australasian Journal of Animal Sciences
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• 제17권1호
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• pp.80-85
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• 2004

The purpose of this experiment was to assess seasonal variation of feed utilization by feed sources and to obtain information on the use of feed resources by comparing seasonal changes of dry matter intake, digestibility, nitrogen balance and feeding behavior in spotted deer (Cervus nippon) fed forest by-product silage (FBS) and corn silage (CS). Dry matter intake (DMI) of FBS was higher than that of CS in both winter and summer. While DMI of both diets was higher in summer, this was not significant at the 5% level. In contrast to DMI, digestible dry matter intake (DDMI) was higher for CS than for FBS in both seasons, but the difference was not significant. Digestibility of dry matter and crude protein was significantly higher (p<0.01) for CS than for FBS, whereas digestibility of crude fiber was significantly higher (p<0.01) for FBS than for CS in both seasons. Seasonal digestibility of dry matter and crude fiber for FBS was significantly greater (p<0.01) in summer than in winter: In summer, seasonal digestibility was 57.2% for dry matter and 55.5% for crude fiber, and in winter, 50.8% for dry matter and 30.7% for crude fiber. On the other hand, seasonal digestibility of crude protein was higher (p<0.01) in winter (42.1%) than in summer (32.3%). No significant difference (p>0.05) was found between the two seasons and diets for nitrogen intake (NI), 18.7 g/d in summer and 19.4 g/d in winter for FBS, 17.7 g/d in summer and 17.7 g/d in winter for CS. Fecal nitrogen was higher (p<0.01) for FBS than for CS and varied little seasonally. There was significant difference (p<0.01) between two seasons in urinary nitrogen, which was little difference between two diets. Retained nitrogen (RN) was different significantly (p<0.01) between two diets in both seasons, but there was little difference between seasons. Deer usually spent longer time on eating FBS than eating CS. Eating FBS took 221 min in summer and 187 min in winter, whereas eating CS took 113 min in summer and 109 min in winter. Deer spent less time on eating food in winter than in summer. Time spent on rumination was longer for FBS than for CS: for FBS, 504 min in summer and 456 min in winter, for CS, 423 min in summer and 279 min in winter. Time varied seasonally with both diets.