• Geomechanics and Engineering
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• 제18권6호
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• pp.627-638
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• 2019

Estimation of representative elementary volume (REV) of jointed rock masses is critical to predict the mechanical behavior of field-scale rock masses. The REV of jointed rock masses at site is strongly influenced by stress state. The paper proposed a method to systematically studied the influence of confining stress on the REV of jointed rock masses with various strengths (weak, medium and strong), which were sourced from the water inlet slope of Xiaowan Hydropower Station, China. A finite element method considering material heterogeneity was employed, a series of two-dimensional (2D) models was established based on the Monte-Carlo method and a lot of biaxial compressive tests were conducted. Numerical results showed that the REV of jointed rock masses presented a step-like reduction as the normalized confining stress increased. Confining stress weakened the size effect of jointed rock masses, indicating that the REV determined under uniaxial compression test can be reasonably taken as the REV of jointed rock masses under complexed in-situ stress environment.

• 대한치과의사협회지
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• 제56권1호
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• pp.18-40
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• 2018

Meta-analysis is a statistical method that combines the results of individual studies on the same topic. This method is becoming popular, due to providing the combined result that individual studies cannot provide and giving a more precise result. Despite meta-analysis having such significance, there were few Korean guides for the use of the Review Manager (RevMan) software. This study will provide a step-by-step guide, using orthodontic mini-screw as a dental example, to help researcher carry out meta-analysis more easily and accurately.

• 대한수의학회지
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• 제45권4호
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• pp.569-574
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• 2005

Enzyme-linked immunosorbent assay (ELISA) for detection of antibodies to reticuloendotheliosis virus (REV) at single serum dilution was standardized. REV HI, one of the Korean field isolates, was inoculated into chicken embryo fibroblast (CEF) cells and was harvested from the culture fluids and cells after 10 to 12 days. Viruses were purified by centrifugation at the $107,000{\times}g$ for 12 hours on 20, 30, 45% (W/V) sucrose gradient. Virus specific fraction was collected and used as ELISA antigen. To standardize ELISA, the optimal concentration of coating antigen ($1{\mu}g/well$) and conjugate (1/1000) was determined by corrected OD (OD value of positive serum-OD value of negative serum) and P/N ratio (OD value of positive serum/OD value of negative serum). To calculate ELISA titer by measuring absorbance at 1/400 single serum dilution, serum titrations were carried out for various sample sera together with standard positive and negative sera. The observed titers of serum samples were plotted against sample/positive (s/p) ratios at 1/400 serum dilution. From the above data, the ELISA titers could be calculated by the equation of $log_{10}$ ELISA titer = 2.2763 ($log_{10}$ s/p) + 3.482 (r = 0.93). For evaluating the sensitivity, the standardized method were compared with conventional agar gel immunodiffusion (AGID) test method using serum samples collected from REV infected field chicken flocks. Fifty seven of 60 samples (95%) were positive for REV by ELISA, whereas only 11 (18.3%) samples were positive by AGID test. This results suggested that the ELISA tests developed in this study could be used for detection of antibodies to REV with high sensitivity.

• Journal of Pharmaceutical Investigation
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• 제22권2호
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• pp.115-124
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• 1992

The characteristics and stabilities of phosphatidylcholine liposomes covalently coupled with immunoglobulin fragments prepared by the REV method were investigated by the dynamic light scattering, absorbance and calcein release. Using a sulfhydryl-reactive phospholipid derivative of N-[4$({\rho}-maleimido-phenyl)$ butyl] phosphatidylethanolamine (MPB-PE), Fab' antibody fragments were covalently combined with preformed large unilamellar vesicles (LUV), Coupling ratio was $250\;{\mu}g$ of $Fab'/{\mu}mol$ of phospholipid in vesicles, From dynamic light scattering, it was found that the size of the vesicles increases as the ratio of cholesterol to lipid increases, but that apparently, the size of liposomes was not sensitive to the existence of Fab' fragments. Regardless of inserting Fab' fragments, the absorbance of liposomes decreased as the amounts of bile salt (BS) added. At very low BS concentrations, BS/lipid aggregates would be formed in the outer vesicles monolayer, while, at the high BS concentrations, mixed micelles would be preferred. The vesicles incorporated with Fab' fragments, however, are more resistant to the bile salts than the MPB-PE vesicle are. The absorbance of vacant liposomes and calcein release resulted in that the Fab' vesicles and MPB-PE vesicles by the REV method are very stable, but that those by the sonication method sufferred the significant change of turbidities.

• 지질공학
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• 제32권1호
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• pp.59-72
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• 2022

본 연구는 부산 기장지역의 백악기 흑운모 화강암에 대하여 삼차원 개별체 수치해석 기반의 응력-변형 해석을 수행하고 절리성 암반의 강도 및 변형특성을 평가하였다. 절리성 암반의 역학적 특성에 대한 규모효과 및 REV를 규명하기 위한 워크플로우가 제시되었으며 연구지역에서 결정된 REV(representative elementary volume) 크기의 DFN(discrete fracture network) 큐브 블록에 대한 블록강도, 변형계수, 전단탄성계수, 체적탄성계수 등의 강도 및 변형 파라미터가 산정되었다. 연구지역의 역학적 REV 크기는 15 m 큐브로 평가되었으며 DFN 큐브 블록의 평균 블록강도 및 평균 변형계수는 각각 신선암의 52.8% 및 57.7%로 추정되었다. 연구지역의 절리성 암반은 역학적으로 뚜렷한 직교이방성을 나타내는 것으로 평가되었으며 삼차원 수치해석을 통하여 산정된 변형 파라미터를 이용하여 선형-탄성의 직교이방성 구성모델이 도출되었다. 연구지역에 대한 직교이방성 구성모델은 등가의 연속체 해석을 통한 터널 및 지하공간의 안정성 평가에 활용될 수 있다.

• 한국정밀공학회지
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• 제18권8호
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• pp.139-149
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• 2001

The effects of the cutting conditions on the surface roughness of workpiece in turning were studied in this paper. The workpieces made of carbon steel SM20C and SM45C were tamed without the support of the tailstock center. Cutting conditions were changed in three or flour steps in each parameter and cutting fluid was used. The surface roughness results of tests were measured and the effects of the cutting conditions were analyzed by the method of analysis of variance. The summary of the experimental research is as follows. The main parameters were cutting speed, fred-rate, depth of cut, and the interactions between speed and fled-rate, speed and depth of cut, and fred and depth of cut. As cutting speed increased, surface roughness showed lower value. The surface roughnesses of feed-rate 0.102 mm/rev and 0.147 mm/rev were better than those of feed-rate 0.05 mm/rev and 0.2 mm/rev.

• Journal of Chest Surgery
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• 제29권8호
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• pp.822-827
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• 1996

소아에서 대동맥 판막 질환의 경우 합리적인 수술법인 Ross술식을 적용함에 있어,우리 나라의 경우 현실적으로 이용에 어려움이 있는 Ross술식에 필요한 동종이식 판막의 사용을 배제한다는 발상으로 10마리의 15 kg가량의 돼지를 이용 REV술식 등을 시행하고 3마리의 성공 례를 3개월 이상 사육하여 성돈이 된 후 그 판막의 발육 및 기능을 관찰하였다. 대동맥 및 폐동맥 등에 협착의 소견은 없었으며, REV술식으로 사용되었던 monocusp보철편의 변형 및 심한 석회화가 관찰되어 이미 판막으로의 기능 은 상실하였으나 발육에는 큰 지장이 없는 것이 확인되어 REV와 Ross술식의 병행 수술요법이 사람에 서도 적 용될 수 있을 것으로 사료되 며, 계속 석회화 방지에 관한 연구가 진행되면 더욱 좋은 성적을 기대할 수 있겠다.

• 한국정밀공학회지
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• 제10권1호
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• pp.34-41
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• 1993

SUS304 is wellknown as difficult-to-machine materials. It is easy to appear workhardened, and workhardening is one of the causes of groove wear on the tool. In this paper, the author would like to compare the width of flank wear with that of groove wear, and to find whether the groove wear can be used as a criterion of a tool life. The design of the twelve tests provides three levels for each variable (speed: 200m/min, 118m/min, 70m/min; feed: 0.3mm/rev, 0.17mm/rev, 0.1mm/rev; depth of cut: 0.4mm, 0.28mm, 0.2mm). The study of tool-life testing by statistical technique follows usual most scientific sequence. So the tool-life predicting equation is calculated by the method of least squares. The overall adequacy of the model can be verified by the analysis of variance. The results obtained are as follows : 1) When SUS304 is cut in 200(m/min), the width of flank wear is much larger than that of groove wear. 2) In cutting speed 118m/min, flank wear is a little larger than groove wear and in the cutting speed 70m/min, the latter is a little larger so that it is reasonable to determine the tool life according the crierion by groove wear in the low cutting speed (less than 70m/min). 3) Owing to the burr the depth of engagement along the cutting edge is extended toward the shank.

• 전기전자학회논문지
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• 제27권4호
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• pp.636-643
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• 2023

본 논문에서는 원전계 환경에서 위상배열안테나를 고속 보정하는 방법이 제안되었다. 원전계에서 수신된 전력만을 통해 각 안테나 요소를 보정하는 기존 rotating-element electric-field vector (REV) 방법을 간소화 한 최대값 보정 방법과, 각 안테나 요소가 아닌 부배열 단위로 묶어서 보정하는 방법이 제안되었다. PPO 알고리즘을 이용하여 위상배열안테나의 분포에 최적화된 파티셔닝을 찾고, 그에 따른 부배열 단위로 보정하여 기존 방법 대비 더 빠른 보정이 가능한 적응형 최대값 보정 방법이 제안 및 시뮬레이션 검증되었다. 보정이 이루어지는 동안 위상배열안테나의 이득이 더 높을 뿐 아니라, 형성되는 빔 패턴이 기존 방법보다 이상적인 빔 패턴에 더 가깝다.

• 한국공작기계학회:학술대회논문집
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• 한국공작기계학회 1995년도 춘계학술대회 논문집
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• pp.1-8
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• 1995

This paper proposed a simple method for measuring surface roughness of ground surface. utilizing non-contact in-process measuring system using the diode laser. The measurement system is consisted of a laser unit with a diode laser and a cylindrical lens a detecting unit with polygon mirror and CCD array sensor. and a signal processing unit with a computer and device. During operation, this measuring system can provide information on surface roughness in the measuring distance with a single sampling and simultanilusly monitor the state of the grind wheel. The experimental results, showed that the increase of the feed rate and the dressing speed an caused increase in the surface roughness and when the surface roughness is 4Rmax-10Rmax, the cutting speed is 1653m/min-1665m/min. the feed rate is 0.2m/min-0.9m/min, the dressing speed is 0.2mm/rev-0.4mm/rev, the stylus method and the in-process method can be obtained the same results. thus under limited working conditions. using the proposed system. the surface roughness of the ground surface during cylindrical grinding can be obtained through the in-process measurement method using the diode laser.