• Journal of the Korean Geotechnical Society
• /
• v.18 no.3
• /
• pp.95-104
• /
• 2002

In this study, a reliability-based design (RBD) procedure for determining design values fur anchored sheet pile wall is proposed considering overturning about the anchor point as the major failure mode. In this design procedure, the depth of embedment of the sheet pile wall is logically chosen in accordance with degrees of uncertainties of design input parameters using approximate probabilistic computation methods. These methods have been successfully used in the geotechnical engineering requiring neither understandings of complex probabilistic theories nor efforts to prepare more data. It was investigated that the design results by the proposed method were compatible with those by commonly used deterministic design methods. Additionally, in an effort to investigate the effects of changes in the degree of uncertainties of major design variables on the design results of the sheet pile wall, a sensitivity analysis was peformed.

• Korean Journal of Food Science and Technology
• /
• v.19 no.5
• /
• pp.420-425
• /
• 1987

For use of sardine oil as an ingredient of food and feed, crude sardine oil obtained by rendering was processed to RBD sardine oil. Alkali deacidification was found to be most efficient with a concentration of 2.5N NaOH and 0.5% excess level at $75^{\circ}C$. Treatment with activated clay alone at $105^{\circ}C$ for 20 min without air admission was effective in reduction of the color intensity of the oil without any formation of the conjugated dienes and trienes of polyunsaturated fatty acids. In deodorization process, as the temperature was increased, color of the oil was to become lighter. The amount of conjugated compounds was, however, increased drastically at higher temperatures above $180^{\circ}C$ for 1hr. and content of polyunsaturated fatty acids was significantly decreased.

• Korean Journal of Microbiology
• /
• v.42 no.3
• /
• pp.230-234
• /
• 2006

To study the mechanism of syncytium formation, novel syncytia-inducing ecotropic murine retrovirus was used. Our previous result showed that amino acid substitutions at the RBD (receptor binding domain) of envelope glycoprotein contribute to syncytium formation. In this study, we have investigated if this fusion phenomenon could occur with retroviral vectors pseudotyped with the novel syncytia-inducing ecotropic murine leukemia virus Env. We have found that these vectors were not able to mediate virus-to-cell fusion in M. dunni murine cell lines. These findings indicate that syncytia-inducing ecotropic murine leukemia virus is capable of generating syncytia during its replication. There was also no correlation between the level of ecotropic murine leukemia virus receptor (mCAT-1) and the fusogenic effect.

• Journal of the Korean Society for Aeronautical & Space Sciences
• /
• v.34 no.2
• /
• pp.56-67
• /
• 2006

The reliability and failure mode effect analysis are effective means to achieve efficient and cost-reduction design for satellite development. The failure rate of COTS (Commercial-Off-The-Shelf) parts required for reliability analysis is not usually provided from the manufacturer. Space environment factors based on empirical data obtained from MIL-HDBK-217F can be applicable to the reliability calculation. As a radiation environment factor, the occurrence rate of SEL (Single Event Latch-up) is additionally incorporated for the failure rate prediction. In this paper, the statistical reliability analysis method for low-cost small satellite using COTS parts is suggested. This statistical reliability analysis was applied to HAUSAT-2 small satellite whose electronic boxes are consisted of many COTS parts to calculate the system reliability at the end of design mission life.

• The Journal of the Acoustical Society of Korea
• /
• v.41 no.2
• /
• pp.210-217
• /
• 2022

Passive source depth estimation has been studied for decades since the source depth can be used for target classification, target tracking, etc. The purpose of this paper is to solve the problem of ambiguity in the previous paper [S.-il. Cho et al. (in Korean), J. Acoust. Soc. Kr. 38, 120-127 (2019)] that source depth is estimated in two points. The patterns of phase shift of Channel Impulse Response(CIR) reflected in ocean surface and bottom is used for removing ambiguity of the source depth estimation, and after removing ambiguity, source depth is estimated at one point through the intersection of CIR. In order to extract CIR in case of unknown source signal and continuous signal or noise, Ray-based blind deconvolution is used. The proposed algorithm is demonstrated through numerical simulation in ocean waveguide.

• IMMUNE NETWORK
• /
• v.21 no.6
• /
• pp.39.1-39.18
• /
• 2021

The high virulent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus that emerged in China at the end of 2019 has generated novel coronavirus disease, coronavirus disease 2019 (COVID-19), causing a pandemic worldwide. Every country has made great efforts to struggle against SARS-CoV-2 infection, including massive vaccination, immunological patients' surveillance, and the utilization of convalescence plasma for COVID-19 therapy. These efforts are associated with the attempts to increase the titers of SARS-CoV-2 neutralizing Abs (nAbs) generated either after infection or vaccination that represent the body's immune status. As there is no standard therapy for COVID-19 yet, virus eradication will mainly depend on these nAbs contents in the body. Therefore, serological nAbs neutralization assays become a requirement for researchers and clinicians to measure nAbs titers. Different platforms have been developed to evaluate nAbs titers utilizing various epitopes sources, including neutralization assays based on the live virus, pseudovirus, and neutralization assays utilizing recombinant SARS-CoV-2 S glycoprotein receptor binding site, receptor-binding domain. As a standard neutralization assay, the plaque reduction neutralization test (PRNT) requires isolation and propagation of live pathogenic SARS-CoV-2 virus conducted in a BSL-3 containment. Hence, other surrogate neutralization assays relevant to the PRNT play important alternatives that offer better safety besides facilitating high throughput analyses. This review discusses the current neutralization assay platforms used to evaluate nAbs, their techniques, advantages, and limitations.

• Journal of The Korean Society of Grassland and Forage Science
• /
• v.35 no.1
• /
• pp.36-42
• /
• 2015

This study was conducted from 2013 to 2014 to explore the feasibility of the cultivation of warm-season grass as an annual Korean forage crop, while concurrently evaluating the characteristics and forage production of warm-season grass in Korea. The experimental design was a randomized block design (RBD) with three replications. Five bermudagrass [Cynodon dactylon (L.) Pers.] cultivars, two teffgrass (Paspalum notatum Flugge) cultivars, and a Kleingrass [Panicum coloratum L.] cultivar were compared for forage production and quality in the middle region of Korea. After seeding, the numbers of days until seedling emergence for bermudagrass and kleingrass were observed at approximately day 11 and day 12, respectively. The heading dates of teffgrass and kleingrass were on July 12 and July 26, respectively. The dry matter (DM) yield of bermudagrass Tifton 85 was usually greater than the other entries. The crude protein content (CPC) and total digestibility nutrient (TDN) for the teffgrass cultivars were usually greater than the other entries at all study sites. The acid detergent fiber (ADF) and in vitro DM digestibility (IVDMD) were similar across all cultivars.

• Korean Journal of Soil Science and Fertilizer
• /
• v.38 no.4
• /
• pp.218-221
• /
• 2005

The present study was investigated in the Chittagong hill forest of Bangladesh to assess the feasibility of ginger cultivation under multipurpose forest and fruit tree species. There were three treatments such as i) ginger grown under open field condition, ie. full sunlight (T1), ii) ginger grown under Gamar tree (spacing of $90{\times}90cm$ (T2) and iii) ginger grown under guava tree (spacing $180{\times}180cm$) tree (T3). The experiment was laid out in randomized block design (RBD) and each treatment was replicated three times. From data it was observed that some morphological parameters of ginger such as plant height, number of leaves per plant, leaf length and leaf breadth were higher in the treatments T2 and T3 as compared to the treatment T1. A positive and linear relationship was observed between the weight of rhizome and yield of ginger which caused the highest yield of ginger ($23.63Mg\;ha^{-1}$) under guava tree species at partial shaded condition in the T3 treatment ($180{\times}180cm$), whereas the lowest yield ($15.64Mg\;ha^{-1}$) was recorded in the T2 treatment when ginger was cultivated under Gamar tree species at closer spacing ($90{\times}90cm$). Therefore, it was revealed that partial shaded condition favoured the optimum growth and yield of ginger, whereas the dense shade from intensively planted tree species badly affected the dry matter production and yield of ginger.

• Korean Journal of Microbiology
• /
• v.46 no.1
• /
• pp.15-20
• /
• 2010

Xenotransplantation of pig organs is complicated by the existence of polytropic replication-competent porcine endogenous retroviruses (PERV) capable of infecting human cells. Two classes of infectious human-tropic replication-competent PERVs (PERV-A and PERV-B) and one class of ecotropic PERV-C are known. The potential for recombination between ecotropic PERV-C and human-tropic PERVs adds another level of infectious risk. A recombinant PERV-A/C (PERV-A14/220) virus is 500-fold more infectious than PERV-A. Two determinants of this high infectivity was identified; one was isoleucine-to-valine substitution at position 140 in RBD (receptor binding domain), and the other lies within the PRR (proline rich region) of the envelope protein. To examine whether the effects of the cytoplasmic tail of the PERV-C Env on fusogenesity also influences infectivity, we constructed a pseudotype retroviral vectors containing MoMLV core protein and PERV envelopes. Pseudotyping experiments with the PERV envelope glycoproteins indicated that recombinant PERV-A/C virus is 10-fold more infectious than PERV-A by lacZ staining. This result supports the suggestion that viral transduction of PERV-A/C is enhanced by a membrane-proximal cytoplasmic amphiphilic ${\alpha}$-helix in PERV-C Env tail.

• Journal of The Korean Society of Grassland and Forage Science
• /
• v.34 no.1
• /
• pp.1-8
• /
• 2014

Field studies were conducted from the years 2009 to 2012 in order to determine the cultivation limit as well as to evaluate the characteristics and forage production of warm season grass in Korea. Two bermudagrass [Cynodon dactylon (L.) Pers.] cultivars, two bahiagrass (Paspalum notatum Flugge) cultivars and a Kleingrass [Panicum coloratum L.] cultivar were compared for forage production and quality in the mid-southern regions of Korea. The experimental design was a randomized block design (RBD) with three replications. The number of days to seedling emergence for bremudagrass and bahiagrass was observed as approximately 12 days and 28 days after seeding, respectively. In Kwangju, the heading dates of bahiagrass and kleingrass were 21 August and 10 July, respectively,. Warm season grass did not winter in the mid-regions (Kimjea, Cheonan) of Korea. All of the Bermudagrass cultivars had higher dry matter (DM) than bahiagrass at the first harvest. The dry matter yield of kleingrass was usually greater than the other entries at all study sites. Peak forage DM production of bermudagrass and bahiagrass cultivars occurred in June and July, respectively. The contents of crude protein (CP) and total digestibility nutrient (TDN) for bermudagrass cultivars were usually greater than the other entries at all study sites. Further, acid detergent fiber (ADF) and in vitro DM digestibility (IVDMD) were similar across all cultivars.