• Title/Summary/Keyword: RAD

Search Result 714, Processing Time 0.028 seconds

An Implementation of Java Source Code Generator using Bean Introspection Mechanism (빈 인트로스펙션 메커니즘을 이용한 자바 소스 코드 생성기 구현)

  • 손승우;김창갑;김흥남
    • Proceedings of the Korean Information Science Society Conference
    • /
    • 1999.10a
    • /
    • pp.391-393
    • /
    • 1999
  • 자바빈 컴포넌트를 이용한 RAD 개발 도구들은 일반적으로 자바빈 컴포넌트를 시각적으로 배치하고, 속성 및 이벤트를 편집할 수 있는 개발 환경을 제공한다. RAD 개발 도구들은 배치된 컴포넌트에 대한 속성과 이벤트를 편집할 수 있는데 특히 이벤트는 개발자의 응용 논리가 포함된 부분으로 완전한 시각화를 통한 구현이 어렵다. 본 논문에서는 자바빈 컴포넌트 기반 개발 환경에서 자바 언어의 인트로스팩션(Introspection) 메커니즘을 이용한 자바 소스 코드 생성 기법을 제시한다. 자바 소스 코드의 생성은 태그로 표시된 템플릿 코드의 생성과 자바의 위임 이벤트 모델을 이용한 이벤트 처리 코드를 생성하여 템플릿 코드에 합성하는 방법을 따른다. 본 논문에서 제시하는 기법은 인트로스펙션에 의해 추출된 정보를 개발자에게 시각적으로 보여주며 개발자의 시각적 조작에 따라 이벤트에 대한 소스코드를 자동으로 생성해준다.

  • PDF

α-Kleisin subunit of cohesin preserves the genome integrity of embryonic stem cells

  • Seobin Yoon;Eui-Hwan Choi;Seo Jung Park;Keun Pil Kim
    • BMB Reports
    • /
    • v.56 no.2
    • /
    • pp.108-113
    • /
    • 2023
  • Cohesin is a ring-shaped protein complex that comprises the SMC1, SMC3, and α-kleisin proteins, STAG1/2/3 subunits, and auxiliary factors. Cohesin participates in chromatin remodeling, chromosome segregation, DNA replication, and gene expression regulation during the cell cycle. Mitosis-specific α-kleisin factor RAD21 and meiosis-specific α-kleisin factor REC8 are expressed in embryonic stem cells (ESCs) to maintain pluripotency. Here, we demonstrated that RAD21 and REC8 were involved in maintaining genomic stability and modulating chromatin modification in murine ESCs. When the kleisin subunits were depleted, DNA repair genes were downregulated, thereby reducing cell viability and causing replication protein A (RPA) accumulation. This finding suggested that the repair of exposed single-stranded DNA was inefficient. Furthermore, the depletion of kleisin subunits induced DNA hypermethylation by upregulating DNA methylation proteins. Thus, we proposed that the cohesin complex plays two distinct roles in chromatin remodeling and genomic integrity to ensure the maintenance of pluripotency in ESCs.

Radiation Effect on Body Weight and Hematological Changes of Hybrid Mice by Conventional Fraction, Large Abdominal Field Irradiation (고식적 분할조사시 전복부 조사량에 따른 잡종 백서의 체중과 혈액상의 변화에 관한 연구)

  • Lee, Sung-Heon;Shin, Sei-One;Kim, Myung-Se
    • Radiation Oncology Journal
    • /
    • v.3 no.2
    • /
    • pp.153-157
    • /
    • 1985
  • Radiation effect on mammals, especially on hematologic changes, has been studied since discovery of x-ray. Various experimental animals were tried for radiobiological studies. 72hybrid mice with conventional faction $(15\times/week)$, large abdominal field $12\times3cm$, from symphysis pubic to xyphoid process) were used. Body weight was declined gradually by increasing irradiation doses, nadir was about $29.7\%$ in male; $30.4\%$ in female at 6000 rad irradiation group. Hemoglobin value was nearly normal throughout entire treatment. Significant dropping of WBC count was noted to $40-50\%$ of pretreatment values by only 1000rad irradiation. Change of differential count was interesting; : lymphocyte proportion showed gradual reduction, instead of gradual increasing of segmented neutrophil. Those proportion were reversed after 6000 rad irradiation. Urinary protein tests showed + - +++, showing no correlation with dosage. Application of our study in clinical combination therapy (radiation + chemotherapy) was discussed.

  • PDF

Cyclic Seismic Testing of Full-Scale Column-Tree Type Steel Moment Connections (반복재하 실물대 실험에 의한 컬럼-트리(Column-Tree) 형식 철골 모멘트 접합부의 내진거동 연구)

  • Lee, Cheol Ho;Park, Jong Won
    • Journal of Korean Society of Steel Construction
    • /
    • v.10 no.4 s.37
    • /
    • pp.629-639
    • /
    • 1998
  • This paper summarizes the results of full-scale cyclic seismic performance tests on three column-tree type steel moment connections. Each test specimen consisted of a $H-600{\times}200$ beam and a $H-400{\times}400$ column of SS41 (SS400). Key parameter included was column PZ (panel zone) strength relative to beam strength. The seismic performance of specimen with stronger PZ tended to be inferior. Total plastic rotations available in the specimens ranged from 1.8 to 3.0 (% rad). The limited test results in this study seem to support the speculation that permitting PZ yielding shall be more beneficial to enhancing total plastic rotation capacity of the moment connection. Beam flange fracture across the heat affected zone and divot-type pullout of the column flange were observed in the tests. A conceptual mechanical model consistent with observed test results was also sought.

  • PDF

Calculation of Magnetic Fields under 3 Phase Power Lines with Branch Lines (분기선로가 있는 3상 전력선로하의 전자파 자계 계산)

  • Kang, Dae-Ho;Lee, Yong-Sik;Kim, Bu-Gyu
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
    • /
    • v.23 no.5
    • /
    • pp.110-119
    • /
    • 2009
  • In this study magnetic fields near electric power lines with branch lines which have a arbitrary angle were derived and formulated by dipole antenna theory and could be calculated easily using the formula. It seems that those formula could be applicable to the consideration of magnetic fields during the design of distribution lines with branch lines. As an example those formulated equations on elements of magnetic fields were applied to a model of 3 phase distribution lines with branch lines and calculated by Matlab programs and the results were presented The analyzed results are follows. The resultant magnetic field is dominated by the componant By all over y-axis in the case of the smaller branched angle $\alpha$ and the lower observed point z. In case of ${\alpha}=\frac{\pi}{2}$[rad], the resultant field is affected by the componant Bx. The resultant field is dominated by the componant Bz at the vicinity of the power lines and it shows very large value at the branch line position of y-axis in case of ${\alpha}>\frac{\pi}{2}$.