• Biotechnology and Bioprocess Engineering:BBE
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• v.5 no.1
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• pp.13-16
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• 2000

Simple procedures have been devised for purifying recombinant human interleukin-2 (hIL-2), which was expressed in Escberichia coli using sequences of glucagon molecules and enterokinase cleavage site as an N-terminus fusion partner. The insoluble aggregates of recombinant fusion protein produced in E. coli cytoplasm were easily dissolved by simple alkaline pH shift $(8\rightarrow12\rightarrow8)$. Following enterokinase cleavage, the recombinant hIL-2 was finally purified by one-step reversed-phase HPLC with high purity. The ease and high efficiency of this simple purification process seem to mainly result from the role of used glucagon fusion partner, which could be applied to the production of other therapeutically important proteins.

• Bulletin of the Korean Mathematical Society
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• v.31 no.2
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• pp.167-172
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• 1994

For a given $C^{*}$-dynamical system (A, G, .alpha.) with a G-simple $C^{*}$-algebra A (that is A has no proper .alpha.-invariant ideal) many authors have studied the simplicity of a $C^{*}$-crossed product A $x_{\alpha{r}}$ G. In [1] topological freeness of an action is shown to guarantee the simplicity of the reduced $C^{*}$-crossed product A $x_{\alpha{r}}$ G when A is G-simple. In this paper we investigate the pure infiniteness of a simple $C^{*}$-crossed product A $x_{\alpha}$ G of a purely infinite simple $C^{*}$-algebra A and a topologically free action .alpha. of a finite group G, and find a sufficient condition in terms of the action on the spectrum of the multiplier algebra M(A) of A. Showing this we also prove that some extension of a topologically free action is still topologically free.

• Journal of the Korean Solar Energy Society
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• v.26 no.2
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• pp.9-18
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• 2006

In this paper, the thermodynamic performance of OTEC cycle was examined. Computer simulation programs were developed for simple Rankine cycle, regenerative Rankine cycle, Kalina cycle, open cycle and hybrid cycle. For the simple Rankine cycle, the results show that newly developed fluids such as R410A and R32 that do not cause stratospheric ozone layer depletion perform as well as R22 and ammonia. Also, simple Rankine cycle OTEC power plant can practically generate electricity when the difference in warm and cold sea water inlet temperatures are greater than $14^{\circ}C$. The regenerative Rankine cycle showed a 1.5 to 2% increase in energy efficiency compared to the simple Rankine cycle while the Kalina cycle employing ammonia/water mixture showed a 2-to-3% increase in energy efficiency, and the overall cycle efficiencies of hybrid cycle and open cycle were 3.35% and 4.86%, respectively.

• Proceedings of the Acoustical Society of Korea Conference
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• 1991.06a
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• pp.151-156
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• 1991

In this paper, we propose a new algorithm for designing the R-G filter that has optimum performance in terms of mean square sidelobe level(MSSL) for the Barker code. The advantage of the conventional R-G filter lies in its simple structure so that it can be easily implemented. However, the conventional R-G filter dose not have optimum performances in terms of peak sidelobe level(PSL), mean sidelobe level(MSL), and MSSL. Recently, a(R-G)LP filter of which filter coefficients are obtained by the linear programming algorithm was proposed and known to have optimum performance in PSL. The proposed (R-G)LS filter keeps the simple structure of the conventional R-G filter and has the filter coefficients that minimizes the sidelobe in the least square sense. The analytic results show that the proposed (R-G)LS filter has better performances than the conventional R-G filter in terms of PSL, MSL, and MSSL. Compared with (R-G)LP filter, the proposed (R-G)LS filter has better performances in terms of MSL and MSSL. The proposed filter design algorithm can be applied to the other binary codes such as truncated pseudonoise(PN) codes and concatenated codes.

• Journal of applied mathematics & informatics
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• v.10 no.1_2
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• pp.167-174
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• 2002

A group G is said to be (l, n, n)-generated if it is a quotient group of the triangle group T(p,q,r)=(x,y,z|x$\^$p/=y$\^$q/=z$\^$r/=xyz=1). In [15], the question of finding all triples (l, m, n) such that non-abelian finite simple groups are (l , m, n)-generated was posed. In this paper we partially answer this question for the sporadic group He. We continue the study of (p, q, r) -generations of the sporadic simple groups, where p, q, r are distinct primes. The problem is resolved for the Held group He.

• Journal of Korea Technology Innovation Society
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• v.2 no.2
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• pp.201-218
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• 1999

The article contains an introduction of possibility of applying Multi-Attribute Utility Theory(MAUT) for priority setting of R&D projects. MAUT is compared with AHP, which is widely used recently. These two techuiques are applied to set priorities of R&D projects In a Government-funded Research Institute. Six criteria are chosen from consultation with decision makers. They are composed of 1) validity as representative projects, 2) possibility of resource mobilization, 3) spillover effect of developed technologies, 4) possibility of success, 5) scope of participation and 6) clarity of research goal. To set priorities of R&D projects, SMART(Simple MultiAttribute Rating Technique) and DVM(Difference Value Measurement) out of many MAUT methods are used to design the utility function and to determine the weights among criteria. The aggregation model is additive on the assumption the criteria are independent. AHP executes pairwise comparisons for criteria and alternatives. From the results of the case study, the results and theoretical characteristics are compared.

• Bulletin of the Korean Mathematical Society
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• v.52 no.5
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• pp.1549-1557
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• 2015

Characterizations of closed subgroups in abelian groups have been generalized to modules in essentially dierent ways; they are in general inequivalent. Here we consider the relations between these generalizations over commutative rings, and we characterize the commutative rings over which they coincide. These are exactly the commutative noetherian distributive rings. We also give a characterization of c-injective modules over commutative noetherian distributive rings. For a noetherian distributive ring R, we prove that, (1) direct product of simple R-modules is c-injective; (2) an R-module D is c-injective if and only if it is isomorphic to a direct summand of a direct product of simple R-modules and injective R-modules.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.14 no.5
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• pp.87-93
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• 2014

For n/m=qm+r, there is no simple divisibility rule for simple m=7 such that is the n multiply by m? This problem can be more complex for two or more digits of m. The Dunkels method has been known for generalized divisibility test method, but this method can not compute very large digits number that can not processed by computer. This paper suggests simple and exact divisibility method for m completely irrelevant n and m of digits. The proposed method sets $r_1=n_1n_2{\cdots}n_l(mod m)$ for $n=n_1n_2n_3{\cdots}n_k$, $m=m_1m_2{\cdots}m_l$. Then this method computes $r_i=r_{i-1}{\times}10+n_i(mod m)$, $i=2,3,{\cdots}k-l+1$ and reduces the digits of n one-by-one. The proposed method can be get the quotient and remainder with easy, fast and correct for various n,m experimental data.

• Genomics & Informatics
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• v.20 no.3
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• pp.35.1-35.9
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• 2022

Microsatellites or simple sequence repeats are motifs of 1 to 6 nucleotides in length present in both coding and non-coding regions of DNA. These are found widely distributed in the whole genome of prokaryotes, eukaryotes, bacteria, and viruses and are used as molecular markers in studying DNA variations, gene regulation, genetic diversity and evolutionary studies, etc. However, in vitro microsatellite identification proves to be time-consuming and expensive. Therefore, the present research has been focused on using an in-house built java pipeline to identify, analyse, design primers and find related statistics of perfect and compound microsatellites in the seven complete genome sequences of coronavirus, including the genome of coronavirus disease 2019, where the host is Homo sapiens. Based on search criteria among seven genomic sequences, it was revealed that the total number of perfect simple sequence repeats (SSRs) found to be in the range of 76 to 118 and compound SSRs from 01 to10, thus reflecting the low conversion of perfect simple sequence to compound repeats. Furthermore, the incidence of SSRs was insignificant but positively correlated with genome size (R² = 0.45, p > 0.05), with simple sequence repeats relative abundance (R² = 0.18, p > 0.05) and relative density (R² = 0.23, p > 0.05). Dinucleotide repeats were the most abundant in the coding region of the genome, followed by tri, mono, and tetra. This comparative study would help us understand the evolutionary relationship, genetic diversity, and hypervariability in minimal time and cost.

• Journal of the Korean Mathematical Society
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• v.50 no.5
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• pp.1051-1066
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• 2013

By utilizing known characterizations of ${\omega}$-Noetherian rings in terms of injective modules, we give more characterizations of ${\omega}$-Noetherian rings. More precisely, we show that a commutative ring R is ${\omega}$-Noetherian if and only if the direct limit of GV -torsion-free injective R-modules is injective; if and only if every R-module has a GV -torsion-free injective (pre)cover; if and only if the direct sum of injective envelopes of ${\omega}$-simple R-modules is injective; if and only if the essential extension of the direct sum of GV -torsion-free injective R-modules is the direct sum of GV -torsion-free injective R-modules; if and only if every $\mathfrak{F}_{w,f}(R)$-injective ${\omega}$-module is injective; if and only if every GV-torsion-free R-module admits an $i$-decomposition.