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Stimulation-Oriented Interventions for Behavioral Problems among People with Dementia: A Systematic Review and Meta-Analysis (치매 환자의 문제행동을 위한 자극지향적 중재의 효과 연구: 체계적 고찰과 메타분석)

  • Kim, Eun Young;Hwang, Sung-Dong;Kim, Eun Joo
    • Journal of Korean Academy of Nursing
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    • v.46 no.4
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    • pp.475-489
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    • 2016
  • Purpose: This study was a systematic review and meta-analysis designed to investigate the effects of stimulation-oriented interventions for behavioral problems among people with dementia. Methods: Based on the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA), a literature search was conducted using seven electronic databases, gray literature, and other sources. Methodological quality was assessed using the Scottish Intercollegiate Guidelines Network (SIGN) for randomized controlled trials (RCTs). Data were analyzed using R with the 'meta' package and the Comprehensive Meta-Analysis (CMA 2.0) program. Results: Sixteen studies were included for meta-analysis to investigate the effect of stimulation-oriented interventions. The quality of individual studies was rated as '++' for eight studies and '+' for the rest. The effect sizes were analyzed according to three subgroups of interventions (light, music, and others); Hedges' g=0.04 (95% CI: -0.38~0.46), -0.23 (95% CI: -0.56~0.10), -0.34 (95% CI: -0.34~0.00), respectively. To explore the possible causes of heterogeneity ($I^2=62.8%$), meta-regression was conducted with covariates of sample size, number of sessions, and length of session (time). No moderating effects were found for sample size or number of sessions, but session time showed a significant effect (Z=1.96, 95% CI: 0.00~0.01). Finally, a funnel plot along with Egger's regression test was performed to check for publication bias, but no significant bias was detected. Conclusion: Based on these findings, stimulation-oriented interventions seem to have a small effect for behavioral problems among people with dementia. Further research is needed to identify optimum time of the interventions for behavioral problems among dementia pateints.

Production responses of Holstein dairy cows when fed supplemental fat containing saturated free fatty acids: a meta-analysis

  • Hu, Wenping;Boerman, Jacquelyn P.;Aldrich, James M.
    • Asian-Australasian Journal of Animal Sciences
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    • v.30 no.8
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    • pp.1105-1116
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    • 2017
  • Objective: A meta-analysis was conducted to evaluate the effects of supplemental fat containing saturated free fatty acids (FA) on milk performance of Holstein dairy cows. Methods: A database was developed from 21 studies published between 1991 and 2016 that included 502 dairy cows and a total of 29 to 30 comparisons between dietary treatment and control without fat supplementation. Only saturated free FA (>80% of total FA) was considered as the supplemental fat. Concentration of the supplemental fat was not higher than 3.5% of diet dry matter (DM). Dairy cows were offered total mixed ration, and fed individually. Statistical analysis was conducted using random- or mixed-effects models with Metafor package in R. Results: Sub-group analysis showed that there were no differences in studies between randomized block design and Latin square/crossover design for dry matter intake (DMI) and milk production responses to the supplemental fat (all response variables, $p{\geq}0.344$). The supplemental fat across all studies improved milk yield, milk fat concentration and yield, and milk protein yield by 1.684 kg/d (p<0.001), 0.095 percent unit (p = 0.003), 0.072 kg/d (p<0.001), and 0.036 kg/d (p<0.001), respectively, but tended to decrease milk protein concentration (mean difference = -0.022 percent unit; p = 0.063) while DMI (mean difference = 0.061 kg/d; p = 0.768) remained unchanged. The assessment of heterogeneity suggested that no substantial heterogeneity occurred among all studies for DMI and milk production responses to the supplemental fat (all response variables, $I^2{\leq}24.1%$; $p{\geq}0.166$). Conclusion: The effects of saturated free FA were quantitatively evaluated. Higher milk production and yields of milk fat and protein, with DMI remaining unchanged, indicated that saturated free FA, supplemented at ${\leq}3.5%$ dietary DM from commercially available fat sources, likely improved the efficiency of milk production. Nevertheless, more studies are needed to assess the variation of production responses to different saturated free FA, either C16:0 or C18:0 alone, or in combination with potentially optimal ratio, when supplemented in dairy cow diets.

Correlation of expression and activity of matrix metalloproteinase-9 and -2 in human gingival cells of periodontitis patients

  • Kim, Kyung-A;Chung, Soo-Bong;Hawng, Eun-Young;Noh, Seung-Hyun;Song, Kwon-Ho;Kim, Hanna-Hyun;Kim, Cheorl-Ho;Park, Young-Guk
    • Journal of Periodontal and Implant Science
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    • v.43 no.1
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    • pp.24-29
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    • 2013
  • Purpose: Matrix metalloproteinases (MMPs) are capable of degrading extracellular matrix, and they are inducible enzymes depending on an inflammatory environment such as periodontitis and bacterial infection in periodontal tissue. Gingival inflammation has been postulated to be correlated with the production of MMP-2 and MMP-9. The objective of this study was to quantify the expression and activity of MMP-9 and -2, and to determine the correlation between activity and expression of these MMPs in human gingival tissues with periodontitis. Methods: The gingival tissues of 13 patients were homogenized in $500{\mu}L$ of phosphate buffered saline with a protease inhibitor cocktail. The expression and activity of MMP-2 and -9 were measured by enzyme-linked immunosorbent assay and Western blot analysis, and quantified by a densitometer. For the correlation line, statistical analysis was performed using the Systat software package. Results: MMP-9 was highly expressed in all gingival tissue samples, whereas MMP-2 was underexpressed compared with MMP-9. MMP-9 activity increased together with the MMP-9 expression level, with a positive correlation (r=0.793, P=0.01). The correlation was not observed in MMP-2. Conclusions: The expression of MMP-2 and -9 might contribute to periodontal physiological and pathological processes, and the degree of MMP-9 expression and activity are predictive indicators relevant to the progression of periodontitis.

Job Satisfaction and its Relationship to Job Characteristics of School Foodservice Dietitians (학교급식 영양사의 직무만족도와 그에 영향을 미치는 직무특성 요인 분석)

  • Yang, Il-Sun;Ham, Seon-Ok
    • Journal of the Korean Society of Food Culture
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    • v.8 no.1
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    • pp.11-19
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    • 1993
  • The purposes of this study were to: (a) measure the levels of job satisfaction with five facets of a job: the work itself, promotion, pay, supervision and co-workers and (b) investigate relationships between job characteristics and job satisfaction levels of the dietitians in school foodservice. Subjects consisted of 151 dietitians, with 91 in Seoul and 60 in KyoungKi-Do. The survey form was developed on modifying Job Descriptive Index developed by Smith, Kendall, Hulin and Job Characteristics Inventory developed by Sims, Szilagy, Keller. The responding rate was 81.7%. Data were analyzed for frequencies, means, t-test, ANOVA, Pearson correlation and multiple regression using SPSS PC Package. The results of this study were as follows: 1) Less than a half of the sample(40.9%) were 31 to 35 years, married were 62% and junior college graduates were 33.9%. 2) A striking majority of the respondents(81.7%) ranked work itself as the the most important aspect of their jobs. 3) The dietitians were the most satisfied with work itself, then supervision, co-workers, wage and promotion in decreasing order. 4) In relations of demographic factors to the job satisfaction, satisfactions with wage and co-workers were found significantly related to education. 5) Task identity was the most prevalent job characteristics. 6) The $R^2$ for the multiple regression model was 0.26, indicating that 26% of the variance in job satisfaction could be accounted for the job characteristics. This model showed that friendship of job characteristics made the greatest contributions. The second was variety and the third was dealing with others. Especially dealing with others was negatively related to job satisfaction.

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Evaluation of the Possibility of Daily Flow Data Generation from 8-Day Interval Measured Flow Data using SWAT-CUP (SWAT-CUP을 이용한 8일간격 유량측정자료의 일유량 확장 가능성 평가)

  • Jung, Jaewoon;Cho, Sohyun;Lim, Byungjin;Oh, Taeyoun;Ham, Sangin;Kim, Kapsoon
    • Journal of Korean Society on Water Environment
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    • v.28 no.4
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    • pp.595-600
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    • 2012
  • This study is to assess the application of SWAT-CUP(Soil and Water Assessment Tool-Calibration Uncertainty Programs) and to extend daily flow data from 8-day interval flow data which has been measured by Korean Ministry of Environment(MOE). Model sensitivity analysis and calibration were performed with sequential uncertainty fitting(SUIF-2), which is one of the programs interfaced with SWAT, in the package SWAT-CUP. The most sensitive parameters were SOL_K.sol, CH_N2.rte, CN2.mgt, SOL_BD.sol, ALPHA_BF.gw, ALPHA_BNK.rte, SOL_AWC.sol, CH_K2.rte, SFTMP.bsn, GW_DELAY.gw. Following the sensitivity analysis, SWAT-CUP calibration was carried out using 8-day interval flow data from January 2008 to December 2010. The results were then assessed based on the visual agreement and simulated flow plots and the performance statistics generated $R^2$ and NSE which are 0.71 and 0.61 respectively. Results of these statistics indicated that there was a good agreement between the observed and simulated flow. To extend daily flow data from 8-day interval flow data, parameters, which were estimated by SWAT-CUP, re-entered for SWAT model. As a result, the observed flow data were found to reflect the trend of simulated flow data. From these results, it is thought that this method could be used to provide daily flow data using 8-day interval flow data.

A Study on RGBY LED Light using a Vacuum Printing Encapsulation Systems Method (진공 프린팅 성형 인쇄법(VPES)을 이용한 R.G.B.Y(Red, Green, Blue, Yellow) LED 광원 연구)

  • Jang, Min-Suk;Kim, Yeoung-Woo;Shin, Gi-Hae;Park, Joung-Wook;Hong, Jin-Pyo;Song, Sang-Bin;Kim, Jae-Pil
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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    • v.25 no.2
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    • pp.10-18
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    • 2011
  • In order to develop highly-integrated RGBY(Red, Green, Blue, Yellow) LED light, a high thermal radiation ceramic package was manufactured, and the encapsulation process was applied with a vacuum printing encapsulation system(VPES). After the completion of vacuum printing, the shape of the encapsulation layer could be controlled by heat treatment during the curing process, and the optical power became highly increased as the encapsulation layer approached a dome shape. The optical characteristics involved in a Correlated Color Temperature(CCT), a Color Rendering Index (CRI), and the efficiency of RGBY LED light were able to be identified by the experimental designing method. Regarding the characteristics of the white light of RGBY LED light, which were measured on the basis of the aforementioned optical characteristics, CRI posted 88, CCT recorded 5,720[$^{\circ}K$], and efficiency exhibited 52[lm/W]. The chip temperature of RGBY LEDs was below 55[$^{\circ}C$] when the consumption power of LED chips was 0.1[W] for the red, 0.3[W] for the green, 0.08[W] for the blue, and 0.24[W] for the yellow. Also, the thermal resistance of the highly-integrated RGBY LED light measured by T3Ster was 2.3[K/W].

A Study of Factors Affecting Intention to Use of Using Technology-based Self-services for Smart Airport (스마트 공항 추진을 위한 기술기반셀프서비스의 사용의도에 영향을 미치는 요인에 관한 연구)

  • Bae, Ji Hyun;Park, Jihye;Lee, Hanna;Choi, Jeongil
    • Journal of Korean Society for Quality Management
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    • v.47 no.4
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    • pp.795-806
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    • 2019
  • Purpose: The purpose of this study was to propose useful suggestions by analyzing the causal relationship between technology-based self-service for smart airport and intention to use. Methods: The data was collected by using the structured questionnaires. The proposed research model is tested using 231 valid questionnaires by R.3.2.1 plspm package. Results: The results of this study are as follows; the effecting factors of technology based self service for introducing smart airport, it was found that the effects of personal innovativeness and enjoyment and responsiveness, social impact were significant for acceptance and personal innovativeness was not significant on perceived usefulness. This study suggests significant factors on the implementation of smart airports and technology-based self-service. It also introduced new technologies in the future by looking at various characteristic factors that affect the intention of using technology-based self-service to promote smart airports. Conclusion: Airports and aviation industries need to have easy access to the airport's technology-based self-services to build a successful smart airport and create an environment that can be used appropriately at the time the customer wants. Also when customers use technology-based self-service devices, they should consider to maximize the positive emotions (emotional values such as pleasure or fun) that customers feel.

Oral health knowledge and oral hygiene care among some orthodontic patients (일부 교정장치 장착환자의 구강보건지식 및 구강위생관리 실천도)

  • Kang, Yong-Ju
    • Journal of Korean society of Dental Hygiene
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    • v.12 no.5
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    • pp.1059-1069
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    • 2012
  • Objectives : The purpose of this study was to examine the knowledge of orthodontic patients about oral health knowledge and their actual oral hygiene care, which affected the oral hygiene of orthodontic patients. It's specifically meant to provide information on the prevention of the possible side effects of orthodontic treatment and the promotion of the oral health of orthodontic patients. Methods : This study were 227 orthodontic patients of dental clinics specialized in orthodontics. The collected data were analyzed by the statistical package SPSS WIN 18.0. Results : 1.As for Oral health knowledge, they had the best knowledge about smoking and dental checkup among the subfactors of oral health knowledge. 2. As to actual oral hygiene care, what they did best was doing toothbrushing before sleeping and what they did worst was avoiding eating food injurious to teeth. 3. They scored highest in the right toothbrushing(3.85), the use of oral hygiene supplies(3.62), the prevention of periodontal diseases(3.13) in the subfactors of actual oral hygiene care. They scored lowest in dental checkup and diet(2.99). 4. There were significant differences among the patients in oral health knowledge according to age(F=2.95, p<.05). Those who received another treatment during orthodontic treatment had a better oral health knowledge than the others who didn't, and the gap between the two was statistically significant(t=2.26, p<.05). 5. There were differences among the patients in actual health hygiene care according to gender(t=2.71, p<.01), age(F=4.40, p<.01), educational experiences about oral hygiene care(t=3.06, p<.01) and experience of receiving another treatment during orthodontic treatment(t=2.56, p<.05). 6. There was a positive correlation between oral health knowledge and oral hygiene care(r=.261, p<.001). Conclusions :The above-mentioned findings suggest that more education of diet and toothbrushing should be provided for orthodontic patients to improve their oral health care.

A Study on Standards for Pressure Relief Valve Vent Pipes from LPG Storage Tanks (LPG용 압력방출밸브 방출관 설치기준 개선방안)

  • Lee, Jin-Han;Eom, Suk-Hwa;Kim, Lae-Hyun
    • Journal of the Korean Institute of Gas
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    • v.16 no.4
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    • pp.59-64
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    • 2012
  • The dispersion of gas discharged from the vent pipes of pressure relief valves attached LPG (Liquefied Petroleum Gas) storage tank was studied. In general, vent pipes should be positioned so that they discharge vertically upwards in a safe place, and installed so that, in the event of ignition of discharged gas, flame impingement on any vessel, equipment or piping is avoided[1][2]. In Korea, on the other hand, there are various type of the end of vent pipes because there is no rule for discharge directions from the vent pipes. In this paper, we took 4 types of vent directions from the pipes in to account, such as vertically upward, vertically downward, vertically 4-way and horizontally 2-way direction. A software package, FLACS, was adopted to simulate gas dispersion from the vent pipes. We found that vertically downward, vertically 4-way and horizontally 2-way discharge from vent pipes were undesirable to avoid ignition on near ground. Therefore, it was obvious that vertically upward opening of a vent pipe is the best option to discharge in a safe place.

Follow-up study on educational effect of human body exploration camp for elementary students : The correlation between satisfaction, academic understanding and attitude for health (인체탐험캠프에 참가한 초등학생들의 만족도, 지식이해도, 태도 간의 상관관계 분석)

  • Kim, Kwang-Hwan;Kim, Jee-Hee;Park, Jeong-Hyun
    • Proceedings of the KAIS Fall Conference
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    • 2010.11b
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    • pp.904-906
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    • 2010
  • 인체탐험캠프의 목적은 청소년들에게 인체와 의학에 대한 올바른 지식을 전달하고 이와 더불어 건강에 대한 올바른 가치관을 정립하는 데 있다. 본 연구에서는 2009년에 개최된 제11회 인체탐험캠프에 참가한 초등학생을 대상으로 사전, 사후, 추후 설문조사를 통하여 만족도, 지식이해도 및 태도 간의 상관관계와 교육효과의 지속 여부를 조사하였다. 설문문항은 참가자의 일반적 특성, 지식이해도 및 태도로 구분하여 개발하였으며, 총 60문항이다. 설문조사는 캠프가 시작하기 직전 및 직후, 그리고 추후(3개월 후)로 나누어 총 3회 실시하였다. 조사 대상은 참가자 중 초등학생 61명이다. 본 연구의 수집된 자료는 SPSS(Statistical Package for the Social Science) WIN 13.0 프로그램을 이용하여 분석하였다. 초등학생의 지식이해도는 사전 11.34${\pm}$2.79, 사후 17.25${\pm}$2.31, 추후 14.23${\pm}$3.65로 사전과 사후, 사전과 추후를 비교한 결과 유의하게 증가한 것을 알 수 있었다(p<0.001). 태도 변화는 사전 3.87${\pm}$0.51, 사후 4.03${\pm}$0.49, 추후 3.96${\pm}$0.47로 사전과 사후(p<0.001), 사전과 추후(p<0.05)에서 유의하게 증가한 것을 알 수 있었다. 캠프에 대한 만족도는 태도 변화와 밀접한 관련이 있는 것으로 나타났다(r=.737, p<.001). 그러나 지식이해도와 태도변화 사이에는 통계적인 상관관계를 보이지 않았다. 결론적으로 인체탐험캠프는 의학 분야의 실험실습 중심의 체험학습 프로그램을 제공하여 초등학생들의 인체와 건강에 대한 지식이해도를 향상시켰으며, 긍정적인 태도변화를 유도하였다. 이는 인체탐험캠프가 학생들의 지식향상 뿐만 아니라 건강에 대한 올바른 가치관 확립에도 이바지 할 수 있는 유익한 프로그램이며, 점차 참여대학 및 관련기관시행기관이 확대될 것으로 기대된다.

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