• Journal of Physiology & Pathology in Korean Medicine
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• v.18 no.6
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• pp.1666-1685
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• 2004

This present study was designed to screen medicinal plants for the treatment of brain diseases such as Parkinson's disease or aging. We tested the effects of the water extracts from 38 species medicinal plants on antioxidant capacity, monoamine oxidase B (MAO-B) inhibitory activity, acetylcholinesterase (AChE) inhibition and antiperoxidation activity in vitro. The water extracts from 38 species were tested on their antioxidant activity using radical scavenging effects against ABTS+. The water extract of C. sappan was showed the highest antioxidant capacity, the antioxidant activity at 1 Jig of herbal extract being 0.38mM TE. Lipid peroxidation in brain homogenates induced by NADPH and ADP-Fe/sup 2+/ was strong inhibited by C. sappan and R. palmatum extracts. Among the 38 medicinal plants investigated, R. palmatum showed significant biological activity (antioxidant capacity, MAO-B inhibiory activity, and AChE inhibitory activity). The protective efficacy of R. palmatum water extract on 1-methyl-4­phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism and its possible mechanism were studied in C57BL/6 mice. Treatment of R. palmatum water extract protected biomacromolecules such as lipids from oxidative damage induced by MPTP. The content of MDA in brain tissue was decreased significantly by R. palmatum extract. These results suggest that R. palmatum water extract plays on effective role in attenuating MPTP-induced neurotoxicity in mice. This protective effect of R. palmatum might be estimated the result from the inhibitory activity on monoamine oxidase B and the enhancement of antioxidant activity.

• IE interfaces
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• v.25 no.1
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• pp.87-95
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• 2012

Very special and tentative considerations including emotional aspects are required to apply any new mechanism and methodologies for manufacturing fields due to several reasons. This study reviews the characteristics of manufacturing collaborations through specific cases applied digital engineering to enhance the collaboration performance in manufacturing domains. Two cases of collaboration related with automotive manufacturing process are analyzed to extract meaningful insights for better collaboration model suggestions. The first case deals the robot simulation to find out advance errors in jig and fixture design during the various welding process of body-in-whites. The effective communication protocol to share their idea and agreed schedules are essential for this collaboration. More severe requirement of collaboration between R&D and manufacturing departments are studied in the second case for e-coating process. The invisible barriers among different departments are lowered by the process application of Computer Aided Engineering which can make sure their own interesting effectively. Those technical and managerial suggestions can be used when the information system and standard process are sought to implement and update not only when innovation projects are executed.

• Journal of the Earthquake Engineering Society of Korea
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• v.19 no.5
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• pp.247-256
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• 2015

This paper briefly introduces the design seismic loads in Korea (KBC 2009). Then, over 10,000 recorded earthquake ground accelerograms, with their magnitude ranging from 4.0 to 8.0 and their epicentral distance ranging from 0 to 200 km, were used to examine the appropriateness of seismic load defined in Korea known as a low-to-moderate seismicity region. The following conclusions are drawn based on the results: (1) The effective peak ground accelerations (EPA) of recorded earthquake accelerograms under $M{\leq}6.0$ and $R{\geq}15km$ appear to be less than that of MCE in Korea for all site conditions defined in KBC 2009. (2) The design spectrum (two-thirds of the intensity of MCE) in KBC 2009 is comparable to those of earthquake records in the magnitude 6 - 7 and the epicentral distance less than 50 km. Therefore, (3) the intensity of Korean design earthquake is considered to be overly high since the Korea peninsula is generally conceived to be a low-seismicity region.

• Proceedings of the KSME Conference
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• 2001.06a
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• pp.345-350
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• 2001

In order to perform elastic-plastic fracture mechanical analyses, fracture resistance curves for concerned materials are required. 1T-CT specimen was used to obtain fracture resistance curves. But the fracture resistance curve by the 1T-CT specimen was very conservative to evaluate the integrity of the structure. And fracture resistance curve was affected by the specimen geometry and crack plane orientation. The objective of this paper is to be certain the conservativeness of the fracture resistance curve by the 1T-CT specimen and to provide the additional safety margin. For these, the fracture tests using the real pipe specimen and standard 1T-CT specimen test were performed. 4-point bending jig was manufactured for pipe test and direct current potential drop method was used to measure the crack extension and length for pipe test. From the pipe and the 1T-CT specimen test results, it was observed that the J-integral of the 1T-CT specimen test at the crack initiation point was very small compare to that of the pipe specimen test.

• Proceedings of the KIEE Conference
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• 1998.07e
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• pp.1705-1707
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• 1998

In this paper, a superposed discharge type ozonizer was designed and manufactured. The ozonizer is equipped with three electrodes : central electrode, internal electrode and external electrode, and it consists of two gaps. The ozone is generated by superposing silent discharge, which are respectively generated betweens two gaps. This paper describes the following two characteristics : (1) 'the characteristics of discharge with variation with output voltage of AC High Voltage source, quantity of the supplied gas and discharge voltage (2) the characteristics of ozone discharge power, temperature of the supplied gas.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.29 no.1 s.232
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• pp.107-114
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• 2005

In order to analyze the elastic-plastic fracture behavior of a structure, the fracture resistance curve of the material should be known first. The standard CT specimen was used to obtain the fracture resistance curves of a piping system. However, it is known that the fracture resistance curve by the standard CT specimen is very conservative to evaluate the integrity of a structure. Also the fracture resistance curve is effected by the specimen geometry and the dimensions because of the constraint effect. The objective of this paper is to be certain the conservativeness of the fracture resistance curve by the standard CT specimen and to provide an additional safety margin. For these, the fracture tests using a real pipe specimen and the standard CT specimen test were performed. A 4-point bending jig was manufactured for the pipe test and the direct current potential drop method was used to measure the crack extension and the length for the pipe test. Also finite element analyses were performed with a CT specimen and a pipe in order to prove the additional safety margin. From the result of tests and analyses of the pipe and the standard CT specimen, it was observed that the fracture analysis with the standard CT specimen is conservative and the additional safety margin was proved.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.21 no.1
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• pp.66-72
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• 2022

The Mooney-Rivlin second order optimal strain energy function derived through uniaxial tensile test and analysis was applied to a gasket to confirm the internal stress and surface pressure generated during compression. The Taguchi method, a statistical technique, was used to design the optimum shape of the gasket, and through characteristic evaluation, the optimum shape of the gasket was obtained when the reference plane (T: 0.15 mm), contact surface (W: 1.00 mm), and curvature (R: 0.30 mm) were used. It was determined that the optimum shape yields a von Mises stress of 4.83 MPa, and the contact pressure stress is 20.14 MPa, which satisfies breakage and sealing requirements. In the future, we plan to manufacture a jig that can measure surface pressure to conduct comparative verification studies between the test results and analysis results.

• Journal of Korean Association for Spatial Structures
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• v.24 no.1
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• pp.29-36
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• 2024

The paper presents the experimental investigation of RC beams retrofitted with Textile Reinforced Mortar (TRM), featuring enhanced bond capacity. Anchoring systems, including an extension of retrofitting length and the use of chemical anchors, are newly employed to improve the structural performance of the RC beam retrofitted with TRM. For the experimental investigation, a total of seven shear-critical RC beams, with and without stirrups, were designed and constructed. The structural behaviors of specimens retrofitted with the proposed TRM methods were compared to those of non-retrofitted specimens or specimens strengthened with conventional TRM methods. Crack pattern, force-displacement relationship, and absorbed energy were evaluated for each specimen. The experimental results indicate a significant improvement in the shear capacity of the RC beam with the proposed retrofitting method. Therefore, it is concluded that the application of an extended retrofitting length and chemical anchors to the TRM retrofitting method can effectively enhance the bond capacity of TRM, thereby improving the shear performance of RC beams.

• Restorative Dentistry and Endodontics
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• v.31 no.2
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• pp.79-85
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• 2006

To evaluate the effect of vital tooth bleaching agent and alcohol pretreatment on dentin bonding, flat dentin windows were produced on the buccal side of the crowns of fifty-five extracted, human premolars. A bleaching gel, $Opalescence^{(R)}$ with 10% of carbamide peroxide (Ultradent Product, USA) was daily applied on the teeth of three experimental groups for six hours for 10 consecutive days, while teeth of a control group were not bleached. After 6 hours of bleaching gel application the specimens were washed and stored in saline until the next day application. After application of $One-step^{(R)}$ dentin bonding agent (Bisco, USA), $Z-250^{(R)}$ resin (3M-ESPE, USA) was bonded to dentin with a mount jig. Shear bond strength was measured with an Instron machine (Type 4202, Instron Corp., USA) after 24 hours. The results were analyzed using one-way ANOVA and Duncan's multiple range test at p < 0.05. Immediate bonding group showed significantly lower bond strength than un-bleached control group (p < 0.05). Ethanol-treated group showed significantly higher bond strength compared to immediate bonding group (p < 0.05). However, the bond strength of the ethanol treatment group was lower than that of the un-bleached control group (p < 0.05). There were no significant difference in shear bond strength between the 2-week delayed bonding group and the ethanol-treated group (p > 0.05) and between delayed bonding group and un-bleached control group (p > 0.05). In the condition of the present study. it seems that alcohol pretreatment after bleaching procedure can reduce the adverse effect of vital bleaching agent on dentin bonding.

• Journal of the Microelectronics and Packaging Society
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• v.30 no.3
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• pp.102-110
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• 2023

This paper introduces scarf welding process of thin substrates using flexible laser transmission welding (f-LTW) technology. We examined the behavior of tensile strength relative to the scarf angle for flexible applications. Thin plastic substrates with the thickness of less than 100 ㎛ were bonded and a jig to form a slope at the edge of the substrate was developed. By developing the scarf welding process, we successfully created a flexible bonding technology that maintains joint's thickness after the process. The tensile strength of the joint was assessed through uniaxial test, and we found that the tensile strength increases as the slope of bonding interface decreases. By conducting stress analysis at the bonding interface with respect to the slope angle, design factor of bonding structure was investigated. These findings suggest that the tensile strength depends on the geometry of the joint, even under the same process conditions, and highlights the significance of considering the geometry of the joint in welding processes.