• 충청수학회지
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• 제26권1호
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• pp.125-135
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• 2013

We introduce the concepts of fuzzy $(r,\;s)$-regular open sets and fuzzy almost $(r,\;s)$-continuous mappings on the intuitionistic fuzzy topological spaces in ${\check{S}}ostak^{\prime}s$ sense. Also we investigate the equivalent conditions of the fuzzy almost $(r,\;s)$-continuity.

• 한국동물학회지
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• 제38권4호
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• pp.523-530
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• 1995

돼지의 난소 조직내에 존재하는 심방이뇨 호르몬 수용체 분포를 알아 보기 위하여 자가방사법을 통해 125I로 표지한 rANP(1-28)의 특이적 결합 부위를 관찰하였다. 난소 조직 중 125I-rANP(1-28)의 강한 결합 부위는 난포의 과립막 세포층이었으며, 외난포막층에서도 125I-rANP(1-28)의 결합 부위가 관찰되었다. 그러나 내난포막층을 포함한 난소내의 다른 조직과 특히 황체에서는 125I-rANP(1-28)의 결합 부위가 나타나지 않았다. 난포의 과립막 세포층과 외난포막층에서의 이러한 125I-rANP(1-28)의 결합은 다량의 rANP(1-28)에 의하여 완전히 전위되었지만, 펩티드 호르몬인 angiotensin II 및 arginine vasopressin에 의해서는 과량의 농도에서도 전위되지 않아 125I-rANP(1-28)의 결합이 특이적임을 확인하였다. 또한 이러한 특이적 결하은 심방이뇨 호르몬의 생물학적 수용체 외에, 다른 기능을 담당하는 clearance 수용체의 특이적 ligand인 C-ANF에 의해서도 전이되었다. 이상의 결과는 돼지의 난소에 있어서 난포의 과립막 세포층 및 외난포막에 심방이뇨 호르몬의 생물학적 또는 coearance 수용체가 존재함을 보여주며, 이는 심방이뇨 호르몬의 수용체가 난자의 성숙에 관련된 난포의 발달과정에 관여할 수 있음을 시사한다.

• 설비공학논문집
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• 제8권3호
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• pp.423-436
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• 1996

Thermodynamic performance of eight zeotropic R-22 alternative refrigerant mixtures selected by AREP(R-22 Alternative Refrigerants Evaluation Program) and R-32/R-125/R-134a(23%/25%/52%), namely R-407C were evaluated by the "drop-in" simulation method. An existing air conditioner was selected and its design data were used for the simulation. "ARI Test A" air conditions were applied. The degree of vapor superheat at the compressor inlet fixed at $5^{\circ}C$ for all the mixtures. The results of the simulation were compared with those of R-22. COPs of all mixtures except for R-32/R-227ea(35%/65%) and R-32/R-125/R-134a(10%/70%/20%), were higher than that of R-22 by 2%~8%, while the capacities were all lower than that of R-22 by 13%~27%. COP of R-32/R-134a(40%/60%) was 2.4% higher but the capacity was 15% lower than those of R-22. In the case of R-32/R-134a(30%/70%), COP and capacity were 5.5% higher and 15% lower than those of R-22, respectively. Among the ternary mixtures, R-407C and R-32/R-125/R-134a(30%/10%/60%) showed the best performance. COP of R-407C was 2.4% higher than those of R-22 but the capacity was 15% lower.

• 한국전자파학회논문지
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• 제25권11호
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• pp.1197-1200
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• 2014

HEMP 방호시설의 전자파 차폐 성능을 평가하는데 사용하고자 하는 두 시험 규격, IEEE Std. 299 및 MIL-STD-188-125-1은 동일한 방호시설임에도 불구하고, 각기 다른 시험 결과를 제공한다. 특히, 10 kHz~20 MHz 대역의 저주파 자기장 영역에서는 IEEE Std. 299 규격에 의한 시험 결과가 MIL-STD-188-125-1 규격에 비해 20~30 dB 정도 더 낮게 평가됨을 확인하였다. 이러한 결과는 두 규격에서 규정하고 있는 측정 조건이 상이함에 기인하며, 따라서 측정거리의 단축을 위해 IEEE Std. 299 규격을 적용할 경우에는 기존의 MIL-STD-188-125-1 규격에 근거하여 작성된 전자파 차폐 성능 요구는 재조정되어야 한다.

• BMB Reports
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• 제49권6호
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• pp.311-318
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• 2016

Innate immune responses are primary, relatively limited, and specific responses to numerous pathogens and toxic molecules. Protein expression involved in these innate responses must be tightly regulated at both transcriptional level and post-transcriptional level to avoid the development of excessive inflammation that can be potentially harmful to the host. MicroRNAs are small noncoding RNAs (∼22 nucleotides [nts]) that participate in the regulation of numerous physiological responses by targeting specific messenger RNAs to suppress their translation. Recent work has shown that several negative regulators of transcription including microRNAs play important roles in inhibiting the exacerbation of inflammatory responses and in the maintenance of immunological homeostasis. This emerging research area will provide new insights on how microRNAs regulate innate immune signaling. It might show that dysregulation of microRNA synthesis is associated with the pathogenesis of inflammatory and infectious diseases. In this review, we focused on miR-146 and miR-125 and described the roles these miRNAs in modulating innate immune signaling. These microRNAs can control inflammatory responses and the outcomes of pathogenic infections.

• BMB Reports
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• 제48권7호
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• pp.371-372
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• 2015

MicroRNAs (miRNAs) can regulate the expression of genes that are involved in multiple cellular pathways. However, their targets and mechanism of action associated with the autophagy pathway are not fully investigated yet. EWSR1 (EWS RNA-Binding Protein 1/Ewing Sarcoma Break Point Region 1) gene encodes a RNA/DNA binding protein that is ubiquitously expressed and plays roles in numerous cellular processes. Recently, our group has shown that EWSR1 deficiency leads to developmental failure and accelerated senescence via processing of miRNAs, but its role in the regulation of autophagy remains elusive. In this context, we further investigated and found that EWSR1 deficiency triggers the activation of the DROSHA-mediated microprocessor complex and increases the levels of miR125a and miR351, which directly target Uvrag. Interestingly, the miR125a- and miR351-targeted reduction of Uvrag led to the inhibition of autophagy in both ewsr1 knockout (KO) MEFs and ewsr1 KO mice. In summary, our study demonstrates that EWSR1 is associated with the posttranscriptional regulation of Uvrag via miRNA processing. The regulation of autophagy pathway in miRNAs-Uvrag-dependent manner provides a novel mechanism of EWSR1 deficiency-related cellular dysfunction. [BMB Reports 2015; 48(7): 371-372]

• 설비공학논문집
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• 제8권1호
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• pp.45-54
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• 1996

An experimental investigation on the two-phase flow through tube orifices was performed with the refrigerant mixture of R32/125/134a(30/10/60). A series of tests were conducted to generate wide range of data at varying operation conditions with four short tubes. The tests include both single and two-phase flow conditions at the inlet of the short tube with different oil concentrations. Experimental data were presented as a function of major operating parameters and short tube diameter. Based on test results and data analysis, a semi-empirical flow model was developed to predict the mass flow rate through short tube orifices with a given set of conditions. The flow model was formed to cover both single and two-phase flow at the inlet of short tube with considering the effects of oil concentration.

• 대한기계학회논문집B
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• 제20권2호
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• pp.730-740
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• 1996

Boiling heat transfer coefficients of pure refrigerants (R22, R32, R134a, R125, R290, and R600a) and refrigerant mixtures (R32/Rl34a, R290/ R600a, and R32/R125) are measured experimentally and compared with Chen's correlation. The test section is a seamless stainless steel tube with inner diameter of 7.7mm and uniformly heated by applying electric current directly to the tube. Heat fluxes range from 10 to 30kW$^2$. Mass fluxes are set to 424 ~ 742kg/m$^{2}$s for R22, R32, R134a, R32/R134a, and R32/Rl25 ; 265 ~ 583kg/m$^{2}$s for R290, R600a, and R290/R600a. Heat transfer coefficients depend strongly on heat flux at a low quality region and become independent as quality increases. Convective boiling term in the Chen's correlation predicts experimental data of the pure refrigerants fairly well (relative error of 12.1% for the data of quality over 0.2). The correlation for pure substances overpredicts the heat transfer coefficients for nonazeotropic refrigerant mixtures.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2008년도 제35회 하계학술대회 초록집
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• pp.125-125
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• 2008

• 한국재료학회:학술대회논문집
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• 한국재료학회 1998년도 IUMRS-ICEM ABSTRACT BOOK
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• pp.125.3-125
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• 1998