• 한국초지조사료학회지
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• 제15권2호
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• pp.118-123
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• 1995

This experiment was canied out to determine the effects of nitrogen (N) fertilization level (0, 70, 140, 280 and 420 k a a ) on the grass growth, dry matter (DM) production, numtive value, and botanical composition in reed canarygrass (Phalaris ancndinacea L.) pasture. \ulcornerhe cultivar used in this study was Palaton, and the grass was harvested at soiling-hay stage (3 times per year) in 1992 and 1993. As the N level was increased, the plant height, DM produdion, and crude protein (CP) content were significantly increased (P<0.05). When the N was applied at the levels of 0, 70, 140, 280, 420 kg, DM yields were 4,540, 5,316, 6,060, 7,923 and 9,960 kgha, and CP contents were 17.6, 17.4, 17.4, 18.4 and 19.8%, respectively. However, as the N level was increased, DM percentage, total digestible nutrients, and relative feed value were decreased, while the contents of neutral detergent fiber and acid detergent fiber, and bareland were continuously increased, particularly in the plot of N 420 kg fdzation. From the above results, it is suggested that reed canarygrass was one of the sensitive pasture grasses to N fertilizer, and the proper amount of N application was 280 kg/ha/yr for desirable production, nutritive value, and botanical composition in r e d conarygrass pasmre.

• 패션비즈니스
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• 제18권3호
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• pp.148-166
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• 2014

The purpose of this study is to establish the basic materials necessary for red carpet fashion design by examining the formativeness and fashion images of red carpet dresses at film festivals in the Great China Region. For the purpose of this study, research methods include a literature review on the origin and significance of red carpet dresses, the characteristics of film festivals in the Great China Region and their red carpet dresses as well as an analysis of the formative features and images of 615 red carpet dresses collected from each film festival official homepage, diverse media articles, and online search sites (www.google.com, www.hao123.com). The research finding can be summarized as follows: First, the formative features of red carpet dress designs were analyzed herein. It was found that the most frequently appearing type of silhouette was straight followed by hourglass and bulk in order. More specifically these included fit and flare, mermaid, trapeze, and slim in order. For the neckline styles, strapless was the most frequently seen followed by camisole, jewel, and one shoulder. Solid colors were more often seen than multiple colors. Bk, W, R, and YR were the most frequent main solid colors in order. Solid materials were frequent as well, such as soft and shiny materials. Non-patterned and unadorned styles were most frequent as for pattern types and details and trimmings. Second, the fashion images of red carpet dresses in the Great China Region were analyzed. The most frequent images were elegant, feminine, ethnic, modern, classic, avant-garde, others, mannish and sportive, in order.

• Archives of Pharmacal Research
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• 제28권12호
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• pp.1358-1364
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• 2005

In this study, we investigated whether a novel anti-ischemic $K_{ATP}$ opener KR-31378 [(2S,3S,4R)­N'-cyano-N-(6-amino-3,4-dihydro-3-hydroxy-2 -methly-2-dimethoxymethly-2H-benzopyran-4-yl)­N'-benzylguanidine] has protective effect against oxidative stress-induced death in heart-derived H9c2 cells. Cell death was induced by BSO, butionine sulfoximine, which inhibits GSH synthesis and subsequently increases reactive oxygen species (ROS) level. Cell death was quantitatively determined by measuring lactate dehydrogenase (LDH) activity and stained by Hoechst 33258. BSO-induced ROS production and mitochondrial membrane potential (MMP) were measured using 2',7'-dichlorofluorescein diacetate oxidation and rhodamine 123, respectively. Both the LDH release and the ROS elevation induced by treatment of H9c2 cells with 10 mM BSO, were significantly decreased by KR-31378. These protective effect and antioxidant effect of KR-31378 appeared to be independent on $K_{ATP}$ channel opening. Cells exposed to BSO showed an early reduction in MMP, and this reduction in MMP was significantly reversed by treatment with KR-31378. Caspase-3 activity in BSO treated H9c2 cells was remarkably increased, and this increased caspase-3 activity was significantly reversed by KR-31378. In conclusion, our results suggest that KR-31378 can produce cardioprotective effect against oxidative stress-induced cell death through antioxidant mechanism.

• 대한한방부인과학회지
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• 제27권3호
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• pp.116-123
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• 2014

Objectives: This study aims to research correlation of the malondialdehyde level in urinalysis with cold hypersensitivity. Methods: We studied 128 patients visiting ${\bigcirc}{\bigcirc}$ Korean Hospital from March, 2013 to May, 2013. The subjects were categorized into two groups: cold hypersensitivity group (n=46) and control group (n=79). Patients in cold hypersensitivity group had been stressed because of severe cold hypersensitivity. First, We investigated the difference of the level of malondialdehyde between two groups. In addition, temperature of the two points, ST32 and LR3, was measured by using Digital Infrared Thermal Imaging (DITI) to find out whether the extent of cold hypersensitivity is related to the level of malondialdehyde. Results: There is no different characteristics between two groups. The average of malondialdehyde in cold hypersensitivity group ($1613.15{\pm}1260.71$) is significantly higher than in control group ($1170.01{\pm}1015.66$)(p=0.04). But there is no correlation between level of malondialdehyde and the extent of cold hypersensitivity (r=-0.22, p=0.13). Conclusions: Although the level of malondialdehyde in cold hypersensitivity group is higher than in control group, there is no significant correlation between level of malondialdehyde and the extent of cold hypersensitivity.

• 한국정보통신학회논문지
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• 제25권1호
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• pp.115-123
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• 2021

생산관리 시스템은 생산 공정 내의 모든 자원의 공정단위 생산계획을 현장에서 실행하는 것은 물론 생산 관련 품질 데이터까지 다루는 공장정보화시스템이다. 인공지능으로 자동화와 연결성이 극대화되는 4차 산업혁명이 화두가 되면서 제조업체들은 스마트 공장 구축에 관심을 보이나 막대한 구축비와 표준화되지 않은 생산 공정은 스마트 공장구축에 걸림돌이 되고 있다. 그래서 본 논문은 노후화된 공장에서 스마트 공장 구축을 위한 제조관리 시스템을 설계 및 구현한다. 철강 선재 공정을 위한 기초 수준의 스마트 공장을 목표로 Web 기반의 제조공정 시스템을 제안한다. 제안 시스템은 REST API를 사용하여 기존 구축된 ERP 시스템과의 연동을 원활히 지원할 것이며 다양한 기기와 다양한 브라우저에서 사용할 수 있도록 확장성을 고려할 것이다. 제안한 WoT 기반 생산관리시스템을 구현하여 실용성을 보이겠다.

• 한국환경보건학회지
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• 제48권2호
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• pp.96-105
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• 2022

Background: Pyrethroid insecticides account for more than 30% of the global insecticide market and are frequently used in agricultural settings and residential and public pest control among the general population. While several animal studies have suggested that exposure to pyrethroids can alter glucose homeostasis, there is only limited evidence of the association between environmental pyrethroid exposure and diabetes in humans. Objectives: This study aimed to report environmental 3-phenoxybenzoic acid (3-PBA) concentrations in urine and evaluate its association with the risk of diabetes in Korean adults. Methods: We analyzed data from the Korean National Environmental Health Survey (KoNEHS) Cycle 2 (2012~2014) and Cycle 3 (2015~2017). A total of 10,123 participants aged ≥19 years were included. Multiple logistic regressions were used to calculate the odds ratios (ORs) for diabetes according to log-transformed urinary 3-PBA levels. We also evaluated age, sex, education, monthly income, marital status, alcohol drinking, physical activity, urinary cotinine, body mass index, and sampling season as potential effect modifiers of these associations. Results: After adjusting for all the covariates, we found significant dose-response relationships between urinary 3-PBA as quartile and the prevalence of diabetes in pooled data of KoNEHS Cycles 2 and 3. In subgroup analyses, the adverse effects of pyrethroid exposure on diabetes were significantly stronger among those aged 19~39 years (p-interaction<0.001) and those who consumed high levels of cotinine (p-interaction=0.020). Conclusions: Our findings highlight the potential diabetes risk of environmental exposure to pyrethroids and should be confirmed in large prospective studies in different populations in the future.

• 동의생리병리학회지
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• 제35권4호
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• pp.117-123
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• 2021

Gefitinib, a first generation epidermal growth factor receptor tyrosine kinase inhibitor (EGFR TKI), provides obvious clinical benefit in patients with EGFR-mutant non-small cell lung cancer (NSCLC). However, patients ultimately develop gefitinib resistance which mainly caused by EGFR T790M secondary mutation. In the current study, we investigated whether the root extract of Scutellaria baicalensis (SB) overcomes gefitinib resistance. Gefitinib-resistant H1975 human NSCLC cells (EGFR L858R/T790M double mutant) were treated with gefitinib and/or ethanol extract of SB (ESB) to evaluate the effect of ESB on the gefitinib sensitivity. The cell viability was measured by MTT assay and trypan blue exclusion assay. The colony-forming ability was evaluated by anchorage-dependent colony formation assay. Combined treatment with gefitinib and ESB markedly decreased the cell viability and colony formation than single treatment with gefitinib or ESB in H1975 cells. In addition, cells treated with both gefitinib and ESB exhibited a significant increase of sub-G1 DNA content which indicates apoptotic cells compared with those treated with gefitinib or ESB alone. As a molecular mechanism, combined treatment with gefitinib and ESB strongly downregulated the phosphorylation of ERK and JNK than single treatment with gefitinib or ESB. Taken together, our results demonstrate that ESB sensitizes H1975 cells to gefitinib treatment. We cautiously propose that ESB can be used in combination with gefitinib for the advanced NSCLC patients with acquired resistance to EGFR TKIs.

• 한국수산과학회지
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• 제56권1호
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• pp.116-123
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• 2023

Flow-through aquaculture systems generate large amounts of wastewater containing compounds such as solids that can settle near aquafarms and cause eutrophication. The settled solids are often reintroduced into flow-through systems, and aquatic animals can be affected by the solids and pathogens associated with these solids. For a sustainable aquaculture operation, adequate wastewater treatment is required. Hydrocyclones are one of the most promising technologies for the removal of solids in aquaculture wastewater. In this study, a model for performance prediction of hydrocyclones was investigated under three different operating conditions: water temperature, solids concentration, and water inlet velocity. The synthetic solids solution was prepared using settled solids from abalone aquaculture farms. The daily solids removal rates of the tested hydrocyclones ranged from 0.18 to 26.0 g solids-m^-3-day^-1, and removal efficiency ranged from 5.1 to 34.4%. The inlet water velocity had the greatest effect on solids removal and hydrocyclone efficiencies. The following multiregression model equation was derived from the daily solids removal rate (g solids-m^-3-day^-1) results for water temperature (T, ℃), solids concentration (SS, mg-L^-1), and tangential inlet water velocity (TIV, m-sec^-1): daily solids removal rate: f(z)=4.465+0.809TIV-0.375T+0.217SS (r²=0.976).

• 복식문화연구
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• 제31권1호
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• pp.107-123
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• 2023

This research studied the electrical characteristics, IR transmission characteristics, stealth functions, and thermal characteristics of infrared thermal-imaging cameras of copper-sputtered samples. Nylon samples were prepared for each density as a base material for copper-sputtering treatment. Copper-sputtered NFi, NM1, NM2, NM3, NM4, and NM5, showed electrical resistance of 0.8, 445.7, 80.7, 29.7, 0.3, and 2.2 Ω, respectively, all of which are very low values; for the mesh sample, the lower the density, the lower the electrical resistance. Measuring the IR transmittance showed that the infrared transmittance of the copper-sputtered samples was significantly reduced compared to the untreated sample. Compared to the untreated samples, the transmittance went from 92.0-64.1%. When copper sputtered surface was directed to the IR irradiator, the IR transmittance went from 73.5 to 43.8%. As the density of the sample increased, the transmittance tended to decreased. After the infrared thermal imaging, the absolute values of △R, △G, and △B of the copper phase increased from 2 to 167, 98 to 192, and 7 to 118, respectively, and the closer the density of the sample (NM5→NFi), the larger the absolute value. This proves that the dense copper phase-up sample has a stealth effect on the infrared thermal imaging camera. It is believed that the copper-sputtered nylon samples produced in this study have applications in multifunctional uniforms, bio-signal detection sensors, stage costumes, etc.

• 한국재료학회지
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• 제33권11호
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• pp.439-446
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• 2023

Changes in the microstructure and mechanical properties of as-roll-bonded AA6061/AA5052/AA1050 three-layered sheet with increasing annealing temperature were investigated in detail. The commercial AA6061, AA5052 and AA1050 sheets with 2 mm thickness were roll-bonded by multi-pass rolling at ambient temperature. The roll-bonded Al sheets were then annealed for 1 h at various temperatures from 200 to 400 ℃. The specimens annealed up to 250 ℃ showed a typical deformation structure where the grains are elongated in the rolling direction in all regions. However, after annealing at 300 ℃, while AA6061 and AA1050 regions still retained the deformation structure, but AA5052 region changed into complete recrystallization. For all the annealed materials, the fraction of high angle grain boundaries was lower than that of low angle grain boundaries. In addition, while the rolling texture of the {110}<112> and {123}<634> components strongly developed in the AA6061 and AA1050 regions, in the AA5052 region the recrystallization texture of the {100}<001> component developed. After annealing at 350 ℃ the recrystallization texture developed in all regions. The as-rolled material exhibited a relatively high tensile strength of 282 MPa and elongation of 18 %. However, the tensile strength decreased and the elongation increased gradually with the increase in annealing temperature. The changes in mechanical properties with increasing annealing temperature were compared with those of other three-layered Al sheets fabricated in previous studies.