• Transactions of the Korean hydrogen and new energy society
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• v.33 no.4
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• pp.413-418
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• 2022

This paper presents two-phase condensation heat transfer and pressure drop characteristics of R32 and R454B as an alternative refrigerant to R410A in a 9.52 mm OD microfin tube. The test facility has a straight, horizontal test section with an active length of 2.0 m and is cooled by cold water circulated in a surrounding annular space. The heat transfer coefficients of the annular space were obtained using the modified Wilson plot method. Average condensation heat transfer coefficient and pressure drop data are presented at the condensation temperature of 35℃ for the range of mass flux 100-400 kg/m²s. The average condensation heat transfer coefficients of R32 refrigerant are 35-47% higher than R410A at the mass flux considered in the study, while R454B data are similar to R410A. The average pressure drop of R32 and R454B are much higher than R410A and they are 134-224% and 151-215% of R410A, respectively. R32 and R454B have relatively low GWP and high heat transfer characteristics, so they are suitable as alternatives for R410A.

• BMB Reports
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• v.51 no.11
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• pp.602-607
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• 2018

Aberrant expression of microRNAs (miRNAs) plays important roles in carcinogenesis and tumor progression. However, the expression and biological role of miR-301b in triple-negative breast cancer (TNBC) remains unclear. Here we aimed to evaluate the roles and mechanisms of miR-301b in TNBC cells. miR-301b expression was assessed in TNBC specimens and cell lines by quantitative Real-Time PCR (qRT-PCR). TNBC cells were transfected with miR-301b mimics, inhibitors or Cylindromatosis (CYLD) small interfering RNA (siRNA) using Lipofectamine 2000. The functional roles of miR-301b were determined by cell proliferation, colony formation, and apoptosis assays. Western blots and qRT-PCR were used to measure the expression of mRNAs and proteins in the cells. We found that miR-301b was upregulated in TNBC specimens and cell lines. Overexpression of miR-301b promoted cell proliferation in TNBC cells, while inhibited the apoptosis induced by 5-FU. CYLD was downregulated by miR-301b at both mRNA and protein levels in TNBC cells. Dual-luciferase report assay confirmed that miR-301b downregulated CYLD by direct interaction with the 3'-untranslated region(3'-UTR) of CYLD mRNA. $NF-{\kappa}B$ activation was mechanistically associated with miR-301b-mediated downregulation of CYLD. However, inhibition of miR-301b reversed all the effects of miR-301b. In conclusion, miR-301b plays an oncogenic role in TNBC possibly by downregulating CYLD and subsequently activating $NF-{\kappa}B$ p65, and this may provide a novel therapeutic approach for TNBC.

• Journal of the Korean Society for Geothermal and Hydrothermal Energy
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• v.13 no.4
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• pp.14-20
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• 2017

Refrigerant having high global warming potentials will be phased out due to environmental protection issues. R410A has been widely used in geothermal heat pump. However, it has a little high GWP by 2088 value. One of the recommended substitute for R410A refrigerant is R452B which having a GWP by 698 value. In this paper, the heating and cooling performance of the water-to-water geothermal heat pump unit with R452B was experimentally investigated. The performance of the heat pump adopting R452B was also compared with the system applying R410A. The heating and cooling capacity of R452B heat pump system showed a slightly lower values within 2% comparing with R410A system. However, the R452B system's coefficient of performance was enhanced by 5.2% and 13.7% at heating and cooling mode, respectively.

• Korean Journal of Soil Science and Fertilizer
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• v.49 no.5
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• pp.480-488
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• 2016

Soil microbes are widely well known to play an important role for sustainable agriculture in terms of crop healthy cultivation and environmental conservation. In this context, the distributional characteristics of soil microbes according to cropping systems were investigated under rice (R)-rice (R), rice (R)-barley (B)-rice (R), and soybean (S)-barley (B)-soybean (S) cropping condition to get basic informations for sustainable agriculture, where barley was grown for winter, in mid-mountainous loam paddy located at the altitude of 285 m above sea level in Sangju area from 2014 to 2015. Estimating from microbial communities by fatty acid methyl ester (FAME) method, a total biomass of bacteria, actinomycetes, and fungi in R-B-R plot was 37% and 40% higher than that in S-B-S and R-R plots, respectively (p < 0.05). In especial, bacteria and fungi were more in R-B-R plot than those in any other ones. B. japonicum, AMF, and mesophilic Bacillus sp. were also greater in S-B-S plot than those. In the community distribution, however, bacteria and actinomycetes showed comparatively high values in S-B-S plot relative to either R-R or R-B-R plot including rice, in which fungi outstanding. In the correlation between microbial biomass and soil properties changed by the cropping, bacteria was positively correlated with C:N ratio; actinomycetes with exchangeable Ca; fungi with available $P_2O_5$ (p < 0.05). While these microbes showed negative response to water stable aggregates of soil.

• Communications of the Korean Mathematical Society
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• v.37 no.2
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• pp.337-345
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• 2022

Let R ⊆ T be an extension of a commutative ring and S ⊆ R a multiplicative subset. We say that (R, T) is an S-accr (a commutative ring R is said to be S-accr if every ascending chain of residuals of the form (I : B) ⊆ (I : B²) ⊆ (I : B³) ⊆ ⋯ is S-stationary, where I is an ideal of R and B is a finitely generated ideal of R) pair if every ring A with R ⊆ A ⊆ T satisfies S-accr. Using this concept, we give an S-version of several different known results.

• Membrane Journal
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• v.2 no.1
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• pp.59-66
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• 1992

The experimental studies were carried out on ultrafiltration of PEG #6000 and dextran 70T macromole¬cules. using an asymmetric cellulose acetate membrane in a cross flow plane type cell. Effects of pressure difference. feed concentration were studied on permeate flux and observed rejection for both the macromole¬cules. and the concentration polarization layer resistance $R_{b1}$ on permeate flux was analysed. The concentration polarization layer resistance $R_{b1}$ was correlated with the average macromolecule concen¬tration $C_{b1}$ in polarization layer. The resulting dimensionless correlation was expressed as : $\frac{R_{b1}}{{R_m}}=\alpha[\frac{\rho_{b1}}{C_{b1}}]^\beta$

• Bulletin of the Korean Mathematical Society
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• v.47 no.5
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• pp.907-913
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• 2010

Let D be an integrally closed domain with quotient field K, * be a star operation on D, X, Y be indeterminates over D, $N_*\;=\;\{f\;{\in}\;D[X]|\;(c_D(f))^*\;=\;D\}$ and $R\;=\;D[X]_{N_*}$. Let b be the b-operation on R, and let $*_c$ be the star operation on D defined by $I^{*_c}\;=\;(ID[X]_{N_*})^b\;{\cap}\;K$. Finally, let Kr(R, b) (resp., Kr(D, $*_c$)) be the Kronecker function ring of R (resp., D) with respect to Y (resp., X, Y). In this paper, we show that Kr(R, b) $\subseteq$ Kr(D, $*_c$) and Kr(R, b) is a kfr with respect to K(Y) and X in the notion of [2]. We also prove that Kr(R, b) = Kr(D, $*_c$) if and only if D is a $P{\ast}MD$. As a corollary, we have that if D is not a $P{\ast}MD$, then Kr(R, b) is an example of a kfr with respect to K(Y) and X but not a Kronecker function ring with respect to K(Y) and X.

• Journal of Bio-Environment Control
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• v.27 no.4
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• pp.363-370
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• 2018

The succulent plants of Echeveria genus are in increasing demand worldwide, but it is difficult to supply good quality young plants throughout the year because propagation efficiencies are depend on cultivar and environmental factors. This study was carried out to investigate the propagation efficiencies of leaf cutting in Echeveria cultivars at different LED light qualities in a closed-type plant factory system. Leaf cuttings cut from stock plants of six difficult-to-propagated cultivars 'Afterglow (AG)', 'Berkeley Light (BL)', 'Mason (MS)', 'Subsessilis Light (SL)', 'Cream Tea (CT)', and 'Ben Badis (BB)' were put into cutting media in the plant factory system maintained at a temperature of $24{\pm}2^{\circ}C$ and relative humidity of $60{\pm}10%$, and watered with over-head irrigation twice a week. Cuttings were irradiated with sole or mixed red (R, 660 nm), blue (B, 450 nm), green (G, 530 nm), and far-red (FR, 730 nm) LEDs as follows: R10, R8+B2, R5+B5, R7+B2+FR1, and R7+B2+G1. PPFD just above the cuttings was $200{\mu}mol{\cdot}m^{-2}{\cdot}s^{-1}$ and photoperiod was 16/8 (light/dark) hours. As a result, propagation efficiencies were dependent on cultivar. Rooting and shooting were relatively easy in 'SL' but shoot formation in 'AG' was very difficult. Light qualities from LEDs also affected plant regeneration. Light conditions with a higher ratio of B, R5+B5, R7+B2+FR1, and R7+B2+G1, promoted shoot formation and growth but inhibited rooting and root growth. R10 and R8+B2 with a higher ratio of R promoted rooting and root growth and inhibited shoot formation and growth of cuttings. In addition, the treatment with FR increased leaf size and biomass of the all plants. Therefore, further studies are needed to investigate the optimum compositions of LED light quality for the improvement of leaf cutting efficiency in difficultto-propagated Echeveria cultivars.

• Bulletin of the Korean Chemical Society
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• v.23 no.10
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• pp.1429-1435
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• 2002

The absolute stereochemistry of tetrin B (1), an antifungal antibiotic isolated from a soil actinomycete was determined by applying Rychnovsky analysis, the modified Mosher method, and CD exciton chirality to be 4R, 5R, 7S, 9R, 11S, 12R, 13S, 15R, 24S, and 25R.

• Proceedings of the Korean Magnestics Society Conference
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• 1998.10a
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• pp.56-57
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• 1998