• Korean Institute of Interior Design Journal
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• v.14 no.6 s.53
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• pp.212-219
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• 2005

As the development of digital and technological sophistication, architectural speculation hierarchy had been more and further diversified and brought on the changes with system of architectural color meaning. Architectural color had been influences on evocation of effect and meaning by association, had the attributes of communication with human being, in common with precision, non-verbal and non-quantitative creative field. Color could not been defined as one conclusively standard symbol and figured out in inter-relationship with correlation, mental status and interaction. Color in architecture could been promptly defined as the tool of visualization in building or structure through the essential criterion to be measured with shape, space and author's thought. In consequence, color in architecture could been re-defined as the speculation concept for real characteristics creation(color as design factors on architect and color to be expressed by program) in itself, and color supporting system as for transposition of light and space enlargement scheme. Consequently, color in architecture could been turnover from perceived color to anthropological color through the real value creation scheme in itself.

• Journal of Chest Surgery
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• v.24 no.3
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• pp.265-270
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• 1991

Since advent of the prosthetic cardiac valve replacement, much efforts for accurate assessing value function in-vivo have been attempted. To evaluate the postoperative functional and morphological status of the replaced cardiac valve prosthesis, 33 patients with valve replacement were studied by transthoracic and transesophageal 2-dimensional echocardiac imaging as well as by color Doppler flow velocity imaging. Twenty four patients had mitral valve replacement. 6 patients had aortic valve replacement and 3 patients had both mitral and aortic valve replacement. There were 34 mechanical and 2 biological prosthesis. Comparing to transthoracic echocardiography, transesophageal approach showed transvalvular regurgitant jet flow amid the prosthetic mitral valve ring during. systole and much clear visualization of cardiac chamber behind prosthesis which could give shadowing effect to ultrasound beam. According to the quantitative grading by the length and area of mitral regurgitant flow, 24 out of 27 mitral valves revealed mild degree regurgitation considered as physiological after prosthetic bileaflet valve replacement and the other 3 valves including 2 biological prosthesis had moderate degree regurgitation which was regarded as pathologic one. 2 cases of left atrial thromboses and 1 case of paravalvular leakage which were not visible by transthoracic approach were identified by transesophageal echocardiography in patients with mitral valve replacement and patients with aortic valve replacement respectively. We conclude that in patients with prosthetic mitral valve replacement, transesophageal 2-dimensional imaging with color Doppler can suggest reliable information beyond that available from the transthoracic access even though it gives patient some discomfort to proceed.

• BMB Reports
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• v.51 no.10
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• pp.526-531
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• 2018

Protein-Protein Interactions (PPIs) play essential roles in diverse biological processes and their misregulations are associated with a wide range of diseases. Especially, the growing attention to PPIs as a new class of therapeutic target is increasing the need for an efficient method of cell-based PPI analysis. Thus, we newly developed a robust PPI assay (SeePPI) based on the co-translocation of interacting proteins to the discrete subcellular compartment 'processing body' (p-body) inside living cells, enabling a facile analysis of PPI by the enriched fluorescent signal. The feasibility and strength of SeePPI (${\underline{S}}ignal$ ${\underline{e}}nhancement$ ${\underline{e}}xclusively$ on ${\underline{P}}-body$ for ${\underline{P}}rotein-protein$ ${\underline{I}}nteraction$) assay was firmly demonstrated with FKBP12/FRB interaction induced by rapamycin within seconds in real-time analysis of living cells, indicating its recapitulation of physiological PPI dynamics. In addition, we applied p53/MDM2 interaction and its dissociation by Nutlin-3 to SeePPI assay and further confirmed that SeePPI was quantitative and well reflected the endogenous PPI. Our SeePPI assay will provide another useful tool to achieve an efficient analysis of PPIs and their modulators in cells.

• 한국가시화정보학회:학술대회논문집
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• 2007.11a
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• pp.88-91
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• 2007

Animal cells show different behaviors in response to the mechanical properties of the substrates. We hypothesize that the rigidity of the substrates also affects the bacterial motility and controls the colony dynamics. It is found that the colony size of Escherichia colis and Bacillus subtilis grown on the agar plates is correlated with agarose gel concentrations and thus with the substrate rigidity. High- resolution microscopic imaging reveals that bacteria in single colonies form different aggregation patterns on the agar plates with varying gel concentration. We measured the apparent diffusion coefficients in the agarose gel plates made with different gel concentrations. Mathematical modeling and quantitative imaging of dye dispersion in the agar plates suggest that there is a close connection between the diffusion rate and the colony size. Nanoscale pore structures and kinetic constraints in the porous media may have an effect on bacterial colony dynamics.

• 한국가시화정보학회:학술대회논문집
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• 2007.11a
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• pp.105-108
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• 2007

To diagnose the vascular diseases from the viewpoint of hemodynamics, we need detailed quantitative hemodynamic information of related blood flows with a high spatial resolution of tens micrometer and a high temporal resolution in the order of millisecond. For investigating in-vivo hemodynamic phenomena of vascular circulatory diseases, a new diagnosing technique combining a medical radiography and PIV method was newly developed. This technique called 'Angiographic PIV system' consists of a medical X-ray tube, an X-ray CCD camera, a shutter module for generating double pulse-type X-ray, and a synchronizer. Through several preliminary tests, the feasibility of the Angiographic PIV technique was verified. For in-vivo applications to real blood flows, we developed tracer microcapsules, which were optimized to this system, made of a contrast material of iodine and a matrix material of PVA (polyvinylpyrrolidone). In near future, the Angiographic PIV technique will be used for understanding hemodynamic phenomena of vascular diseases and for their early detection.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.41 no.1
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• pp.29-36
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• 2017

The paper presents a basic investigation for the development of cleaning technology employing an annular nozzle ejector for application to cleaning water supply and air bubble generation. The quantitative flow characteristics of the primary and suction flows, the qualitative visualization behavior of the mixed jet, and the percentage concentration of pesticide residual at different values of the ejector screw pitch were investigated. It was seen that the primary flow rate increased, while the mass ratio decreased with increase in screw pitch. Further, the mixed jet behaved like a buoyancy jet or horizontal bubbly jet, and the residual concentration of pesticide first decreased and then increased with increase in screw pitch.

• Applied Microscopy
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• v.38 no.3
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• pp.275-278
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• 2008

Electron tomography (ET) is an electron microscopic technique for obtaining a 3-D image from any electron microscopy specimen and its application in biomedical science has been increased thanks to development of electron microscopy and related technologies during the last decade. There are few researches on ET in Korea during this period. Although the importance of ET has been recognized recently by many researchers, initial approach to electron tomographic research is not easy for beginners. The 4th International Congress on Electron Tomography (4 ICET) was held on Nov $5{\sim}8$, 2006, at San Diego. The program dealt instrumentation, reconstruction algorithm, visualization/quantitative analysis and electron tomographic presentation of biological specimen and nano particles. 1 have summarized oral presentations and analyzed the posters presented on the meeting. Cryo-electron microscopic system was popular system for ET and followed conventional transmission electron microscopic system. Cultured cell line and tissue were most popular specimens analyzed and microorganisms including bacteria and virus also constituted important specimens. This analysis provides a current state of art in ET research and a guide line for practical application of ET and further research strategies.

• Journal of the Korean Society of Safety
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• v.21 no.5 s.77
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• pp.6-11
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• 2006

This study aims to measure a smoke density and velocity by using the PIV method in case a fire occurs in tunnels. By doing so, this will estimate a critical velocity, examine its appropriateness, and present the basic materials necessary for designing a smoke control equipment. For this study, a visualization test was conducted based on the 1/20 miniature of a real tunnel according to the Froude scaling. As a part of basic experiments, a correlation between smoke density and brightness was analyzed here, and a critical velocity was estimated on the condition that a fire breaks out in tunnels. As a result, this study finds that there is a correlation between smoke density and brightness within a range of 100% to 30% transmittance, from which a quantitative smoke density can be obtained. The study also suggests that a critical velocity calculated from the Kennedy formula shows about 10% difference from that estimated in the test.

• Journal of the Korean Institute of Landscape Architecture
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• v.27 no.4
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• pp.143-150
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• 1999

The purpose of this research is to find som ways to model tree forms more efficiently in reference with surveying structural data and handling parameters in plant Editor of AccuRender, the AutoCAD-based rendering software adopting the procedural plant modeling technique. In case of modelling a new tree, because it is efficient to modify an existing tree data as a template, we attempted to classify 81 species' data from existing plant library including conifers and deciduous tree. According to the qualitative characteristics and quantitative parameters of geometrical and branching structure, 8 types of tree form were classified with factor and cluster analysis. Some critical aspects found in the distributions of standardized scores of parameters in each type were discussed for explaining the tree forms intuitively. For adaptability of the resulted classification and typical parameters, 10 species of tree were measured and modelled, and proved to be very similar to the real structures of tree forms. CG or CAD-based plant modelling technique would be recommended not only as a presentation tool but for planting design, landscape simulation and assessment.

• Asian Journal of Atmospheric Environment
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• v.5 no.1
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• pp.56-63
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• 2011

Quantifying the solute composition of a cloud droplet (or a whole droplet) is an important task for understanding formation processes and heating/cooling rates. In this study, a combination of droplet fixation and SR-XRF microprobe analysis was used to visualize and quantify elements in a micro-scale droplet. In this study, we report the preliminary outcome of this experiment. A spherical micro-scale droplet was successfully solidified through exposure to ${\alpha}$-cyano-acrylate vapor without affecting its size or shape. An X-ray microprobe system equipped at the beam line 37XU of Super Photon ring 8 GeV (SPring-8) was applied to visualize and quantify the elemental composition in an individual micro-scale droplet. It was possible to reconstruct 2D elemental maps for the K and Cl contained in a microdroplet that was dispensed from the 10-ppm KCl standard solution. Multi-elemental peaks corresponding to X-ray energy were also successfully resolved. Further experiments to determine quantitative measures of elemental mass in individual droplets and high-resolution X-ray microtomography (i.e., 3D elemental distribution) are planned for the future.