• 한국환경보건학회지
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• 제39권1호
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• pp.32-42
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• 2013

Objectives: Cryptosporidium, a protozoan parasite, has been recognized as a frequent cause of waterborne disease due to its extremely strong resistance against chlorine disinfection. Although there has as yet been no report of a Cryptosporidium outbreak through drinking water in Korea, it is important to estimate the health risk of Cryptosporidium in water supply systems because of the various infection cases in human and domestic animals and frequent detection reports on their oocysts in water environments. Methods: This study evaluated the annual infection risk of Cryptosporidium in tap water using the quantitative microbial risk assessment technique. Exposure assessment was performed upon the results of a national survey on Cryptosporidium on the water sources of 97 large-scale water purification plants in Korea, water treatment efficacy, and daily unboiled tap water consumption. The estimates of the US Environmental Protection Agency on the mean likelihood of infection from ingesting one oocyst were applied for effect assessment. Results: Using probabilistic methods, mean annual infection risk of Cryptosporidiosis by the intake of tap water was estimated to fall within the range of $2.3{\times}10^{-4}$ to $1.0{\times}10^{-3}$ (median $5.7{\times}10^{-4}$). The risk in using river sources was predicted to be four times higher than with lake sources. With 0.5-log higher removal efficacy, the risk was estimated to be $1.8{\times}10^{-4}$, and could then be lowered by one-third. Conclusions: These estimations can be compared with acceptable risk and then used to determine the adequacy and priority of various drinking water quality strategies such as the establishment of new treatment technology.

• Journal of Preventive Medicine and Public Health
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• 제55권6호
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• pp.586-594
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• 2022

Objectives: This study investigated the effectiveness of the social marketing mix approach in increasing students' knowledge about smoking, promoting positive attitudes toward smoking cessation, and decreasing smoking behavior. Methods: This quantitative research study incorporated a quasi-experimental method with a pretest-posttest non-equivalent group design. Using the purposive sampling technique, 152 smoking students were selected as participants. They were divided into 2 equal groups, with 76 students in the control group and 76 in the intervention group. The data were collected using questionnaires and analyzed with the chi-square test, independent t-test, Wilcoxon signed-rank test, and Mann-Whitney U-test. Results: The social marketing mix intervention was effective in increasing the students' knowledge about smoking (p<0.001), improving their attitude toward smoking cessation (p<0.001), and reducing their smoking behavior (p=0.014). Conclusions: This approach should be implemented by local governments to reduce smoking behavior in the community, especially among teenagers, in addition to instituting a smoking ban and applying fines.

• 한국치위생학회지
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• 제20권1호
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• pp.1-9
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• 2020

Objectives: This study conducted a literature review to systematically confirm the quantitative results of individual studies on oral health-related quality of life (OHRQoL) among elderly adults. Methods: Studies on quality of life related to oral health among Korean elderly adults were selected as targets, and literature published in Korean journals until January 10, 2019, was examined. A total of 179 papers were reviewed using RISS, KISS, eArticle, and DBpia, and 17 papers meeting the final conditions were selected for analysis. Factors were categorized with publication year, sample size, gender, and statistical analysis as main variables. Relevant factors and effect sizes were then encoded, and the values of correlation coefficients and correlation effect sizes were coded. Results: After classifying the factors affecting OHRQoL among elderly adults according to common characteristics, four studies related to food and diet, five studies related to xerostomia, and four studies related to dentures and denture satisfaction were found to be related. Conclusions: Overall, various factors affected OHRQoL among elderly adults. Therefore, oral health among elderly adults must be developed and managed considering the various factors related to OHRQoL.

• 보건의료산업학회지
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• 제13권4호
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• pp.19-31
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• 2019

Objectives: The purpose of this study was to analyze research trends in age-friendly research and suggest directions for future research. Methods: For this study, 112 articles related to age-friendly research were selected, from 605 published articles in The Korean Journal of Health Service Management (2007-2018). Content analysis and text network analysis were conducted using SPSS 23.0 and NetMiner 4. Results: First, 2 authors (30.4%) and 4 keywords (45.5%) were the most studied. Most of the studies used quantitative research (93.8%). Primary data (61.9%) and SPSS (77.7%) were the most used for analysis. Second, there were seven common keywords in the top 10 in all the centralities. They were Elderly, Geriatric Hospital, Depression, Care Workers, Long-Term Care Facilities, Experience, and Attitude. Conclusions: This study shows the need for diversity of research topics, subjects, research methods, and analytical tools in future age-friendly related studies. In addition, it suggests activating convergence research in this field linked to various industries and services.

• Asian Pacific Journal of Cancer Prevention
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• 제15권4호
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• pp.1675-1679
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• 2014

Objectives: MicroRNAs (miRNAs) are important regulators of many physiological and pathological processes, including tumorigenesis and metastasis. In this study, we sought to determine the underlying molecular mechanisms of metastatic cervical carcinoma by performing miRNA profiling. Methods: Tissue samples were collected from ten cervical squamous cancer patients who underwent hysterectomy and pelvic lymph node (PLN) dissection in our hospital, including four PLN-positive (metastatic) cases and six PLN-negative (non-metastatic) cases. A miRNA microarray platform with 1223 probes was used to determine the miRNA expression profiles of these two tissue types and case groups. MiRNAs having at least 4-fold differential expression between PLN-positive and PLN-negative cervical cancer tissues were bioinformatically analyzed for target gene prediction. MiRNAs with tumor-associated target genes were validated by quantitative reverse transcription-polymerase chain reaction (RT-PCR). Results: Thirty-nine miRNAs were differentially expressed (>4-fold) between the PLN-positive and PLN-negative groups, of which, 22 were up-regulated and 17 were down-regulated. Sixty-nine percent of the miRNAs (27/39) had tumor-associated target genes, and the expression levels of six of those (miR-126, miR-96, miR-144, miR-657, miR-490-5p, and miR-323-3p) were confirmed by quantitative (q)RT-PCR. Conclusions: Six MiRNAs with predicted tumor-associated target genes encoding proteins that are known to be involved in cell adhesion, cytoskeletal remodeling, cell proliferation, cell migration, and apoptosis were identified. These findings suggest that a panel of miRNAs may regulate multiple and various steps of the metastasis cascade by targeting metastasis-associated genes. Since these six miRNAs are predicted to target tumor-associated genes, it is likely that they contribute to the metastatic potential of cervical cancer and may aid in prognosis or molecular therapy.

• 사상체질의학회지
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• 제22권4호
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• pp.20-29
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• 2010

1. Objectives Our goal is to observe the feasibility of constitution discrimination from computing quantitative roughness index from dynamic friction coefficients and their gradients with the measurement device of skin friction with 3-Axis load cell sensor. 2. Methods In the traditional Korean medicine, skin diagnosis is one of the examination methods to discriminate Sasang constitution since it was known that Tae-eumin has rough skin, and Soyangin has smooth one. It is based on the skin roughness on the back of one's hand for the discrimination. The measurement device of skin friction with 3-axis load cell sensor has been developed in order to provide quantitative skin roughness through dynamic friction coefficients. The effective interval of the coefficients is obtained from the automatic sampling algorithm to use their curvature and slope. Then, Fisher's discriminant function of them makes the discrimination. 3. Results The success rate of extracting the effective interval was about 90% and the discriminant accuracy between Tae-eumin and Soyangin was 70% and 68% for men and women, respectively. The entire methods showed the possibility to distinguish between Tae-eumin and Soyangin by using stochastic properties of roughness index, which can make the entire system to include the measurement, the computation of the roughness index and the discrimination of constitution automatical. 4. Conclusions The measurement device, the automatic sampling algorithm of dynamic friction coefficients and the constitution discrimination algorithm were developed, respectively, and their combination can become the serial and automatic procedure for quantitative and objective skin diagnosis, which mimics the movement of the Oriental medical doctors' skin diagnosis. It can be applied to healthcare as well as the diagnosis of constitution in a u-Health system soon.

• 한국치위생학회지
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• 제21권5호
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• pp.555-565
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• 2021

Objectives: This study was conducted to analyze peri-implantitis bacteria and identify their associations with health status and health activities. Methods: Gingival sulcus fluid at the implant's periodontal pockets sampled from the participants were analyzed by multiplex real time PCR. Results: Participants had strains in the order of 100% F. nucleatum, 98.0% E. corrodens, and 96.0% P. micra, and the correlation between C. rectus and E. nodatum was high (p<0.01). Diabetic group (P. gingivalis, P. nigrescens) hypertension (P. nigrescens), group with four or more periodontal pockets (P. gingivalis, T. dentica, P. intermedia, E. nodatum, and C. rectum), smoking (P. micra, E. corrodens), drinking (T. dentola), and scaling groups (C. rectus) were found to have more strains (p<0.05). Conclusions: Representative pathogenic microorganisms detected in periodontal pockets of implants were similar to dental periodontal pockets; however there were differences in the amount and distribution of microorganisms, and they were affected by health status and health behavior.

• 보건교육건강증진학회지
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• 제22권2호
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• pp.63-76
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• 2005

Objectives: The purpose of this study was to evaluate the effectiveness of K-WIFY model that was a participatory health education program. Based on WIFY, this study developed K-WIFY that was only focused on health related issues rather than all broad ranges of life issues. This study evaluated changes in health related recognition, self-efficacy, self-esteem, social support, perceived benefits, perceived barriers, and situational barriers of the subjects after participating the program. Methods: During from March 16 to April 1, 2004, 216 study subjects of university students were subjected to a quantitative survey and 187 subjects of the total subjects were exposed to qualitative survey. Results: The results were as follows: 1. Health related perceptions were statistically different after taking participatory a health education program using K-WIFY. The amount of improvement was 6.36. 2. After participatory health promotion education using K-WIFY, self-efficacy(p=.029), self-esteem(p=.019) and perceived benefits(p=.031) were statistically higher than before. Conclusions: In conclusion, this study verified the effectiveness of participatory health education promotion using K-WIFY. We recommend K-WIFY to national and regional health promotion plans and health promotion education for university students.

• 한국치위생학회지
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• 제15권3호
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• pp.417-424
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• 2015

Objectives: The purpose of the study is to investigate the relationship between oral health conditions and their subjective oral health perception in the elderly in Gimcheon. Methods: The study subjects were 214 elderly aged over 65 years old in Gimcheon. The study was carried out by direct interview method of from February 20 to 24, 2014. The oral examination was performed by the dentist base on the World Health Organization criteria including direct examination and observation. The questionnaire consisted of sex, type of family, use of medical services, and oral health behavior, The independent variable included three questions of the general characteristics of the subjects, two questions of use of medical services, and two questions of oral health behavior. The subjective oral health perception was composed of heathy and unhealthy. The objective oral health condition was evaluated by number of residual teeth, FT index, MT index, and DMFT index. Results: In the elderly, the number of residual tooth was $8.89{\pm}9.72$ and the number of decayed teeth was $0.03{\pm}0.20$. The numbers of missing teeth and filled teeth were $19.26{\pm}9.65$ and $0.28{\pm}1.01$, respectively. The DMFT index was $19.57{\pm}9.28$. In relation to the subjective oral health perception, 76.6% answered 'good' and 23.4% answered 'bad'. The subjective oral health perception showed a weak quantitative linear relationship of r=0.235 with the number of residual tooth. the subjective oral health perception showed a weak negative linear relationship(p<0.01) of r=-0.225 with the number of missing teeth and r=-0.217 with DMFT(number of decayed missing and filled teeth) index.

• Journal of Preventive Medicine and Public Health
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• 제40권1호
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• pp.36-44
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• 2007

Objectives : There have been few studies examining the differences in health care utilization across social classes during the last year of life. Therefore, in this study we analyzed the quantitative and qualitative differences in health care utilization among cancer patients across educational classes in their last year of life, and derived from it implications for policy. Methods : To evaluate health care utilization by cancer patients in the last year of life, Death certificate data from 2004 were merged with National Health Insurance data (n=60,088). In order to use educational level as a social class index, we selected the individuals aged 40 and over as study subjects (n=57,484). We analyzed the differences in the medical expenditures, admission days, and rates of admission experience across educational classes descriptively. Multiple regression analysis was conducted to evaluate the association between medical expenditures and independent variables such as sex, age, education class, site of death and type of cancer. Results : The upper educational class spent much more on medical expenditures in the last one year of life, particularly during the last month of life, than the lower educational class did. The ratio of monthly medical expenditures per capita between the college class and no education class was 2.5 in the last 6-12 months of life, but the ratio was 1.6 in the last 1 month. Also, the lower the educational class, the higher the proportion of medical expenditures during the last one month of life, compared to total medical expenditures in the last one year of life. The college educational class had a much higher rate of admission experiences in tertiary hospitals within Seoul than the other education classes did. Conclusions : This study shows that the lower educational classes had qualitative and quantitative disadvantages in utilizing health care services for cancer in the last year of life.