• Title/Summary/Keyword: Quantitative Method

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A study on the risk assessment based on the semi-quantitative methodology (준 정량적 방법의 위험성 평가에 대한 연구)

  • Jung, Da-Woon;Oh, Sang-Min;Yoo, Deung-Ryeol;Seo, Jung-Wook;Kim, Du-Ill
    • Proceedings of the KSR Conference
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    • 2011.05a
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    • pp.1425-1432
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    • 2011
  • The various risk assessment methodologies have been introduced in the railway industries. The risk assessment suggested by CENELEC are described with two ways; quantitative and qualitative methods. However, in the industry application level, the quantitative method is hard to apply for a project because of somehow complicated or few statistical figures which was driven from the on-site and the qualitative method is too subject to have the confidence of its results fully. In this paper, the state-of-the-art methods which were suggested in Europe recently are introduced and compared to existing quantitative and qualitative methods. Furthermore, the application measures of railway projects are investigated.

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Isolation and Quantitative Analysis of Icariin from Epimedii Herba (음양곽으로부터 Icariin의 분리 및 함량분석)

  • Lee, Hye-Won;Hwang, Seong-Won;Ko, Byoung-Seob;Kim, Ho-Kyoung
    • Korean Journal of Pharmacognosy
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    • v.32 no.1 s.124
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    • pp.43-48
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    • 2001
  • Epimedii Herba has been used for tonic, cardiotonic, impotency, amnestic and diuretic. Icariin, a main component was isolated from the Epimedii Herba and identified by the spectroscopic methods. In order to evaluate the quality of Epimedii Herba purchased from various regions of Korea, quantitative determination of icariin in Epimedii Herba using HPLC method has been conducted. Quantitative analysis showed the average amount of icariin in commercial 42 samples was 0.34% on the dry weight basis.

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Quantitative Analysis of 6-Gingerol in the Zingiberis Rhizoma By Processing methods (수치에 따른 건강중의 6-Gingerol 함량 분석)

  • Kim, Young-A;Hwang, Seoung-Won;Ko, Byoung-Seob;Kim, Ho-Kyoung
    • Korean Journal of Pharmacognosy
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    • v.33 no.4 s.131
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    • pp.291-295
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    • 2002
  • On the quality control of commercial Zingiberis Rhizoma and its processed product, quantitative determination of 6-gingerol using HPLC method has been conducted. Quantitative analysis off-gingerol in Zingiberis Rhizoma showed average 0.359% in 14 samples collected throughout the regions of Korea. The contents of 6-gingerol in Zingiberis Rhizome were decreased during the processing procedure (0.306%).

Quantitative Analysis of Ziyuglycoside I from Sanguisorbae Radix (지유로부터 Ziyuglycoside I의 함량분석)

  • Kim, Young-A;Hwang, Seong-Won;Ko, Byoung-Seob;Kim, Ho-Kyoung
    • Korean Journal of Pharmacognosy
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    • v.33 no.2 s.129
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    • pp.100-104
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    • 2002
  • Sanguisorbae Radix has hemostatic, analgesic and astrigent properties and it has been used for the treatment of burns, scalds and internal hemorrhage. Ziyuglycoside I was isolated from Sanguisorbae Radix and identified by the spectroscopic methods. In order to evaluate the quality of it, quantitative determination of Ziyuglycoside I in Sanguisorbae Radix using HPLC method has been conducted. Quantitative analysis of Ziyuglycoside I showed average 3.005% in 30 samples collected throughout the regions of Korea.

Quantitative Analysis of 5-hydroxymethyl-2-furaldehyde (5-HMF) in the commercial Rehmanniae Radix Preparata (시판품 숙지황중의 5-hydroxymethyl-2-furaldehyde (5-HMF) 함량분석)

  • Kim, Ho-Kyoung;Jeon, Won-Kyung;Kim, Young-A;Ko, Byoung-Seob
    • Korean Journal of Oriental Medicine
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    • v.9 no.1
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    • pp.129-135
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    • 2003
  • Rehmanniae Radix Preparata attributes good blood circulation and it has been used for the treatment of dizziness, men's sterility, excessive loss of blood and weakness. On the quality control of commercial Rehmanniae Radix Preparata, quantitative determination of 5-hydroxymethyl (5-HMF) using HPLC method has been conducted. Quantitative analysis of S-hydroxymethyl-2-furaldehyde (5-HMF) in commercial Rehmanniae Radix Preparata showed average of $0.136{\pm}0.057%$ in 14 samples collected throughout the regions of Korea.

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Isolation and Quantitative Determination of Dioscin from Smilacis Chinae Radix (토복령(土茯令, Smilacis Chinae Radix)으로부터 Dioscin의 분리 및 함량분석)

  • Seo, Jung-Hak;Lee, Joo-Mi;Kwon, Soon-Jin;Chang, Seung-Yeup;Lee, Kyong-Soon;Son, Kun-Ho
    • Korean Journal of Pharmacognosy
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    • v.32 no.2 s.125
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    • pp.153-156
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    • 2001
  • The methods for isolation and quantitative determination of dioscin, a spirostanol triglycoside, from the roots of Smilax china have been developed. Isolation of dioscin was achieved by silica gel and RP-18 chromatography. The HPLC method used for quantitative determination of dioscin enabled the standardization of the crude drug. It suggests that the content of dioscin in Smilax china should be above 0.01%.

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Purity assessment using quantitative NMR: establishment of SI traceability in organic analysis

  • Choi, Kihwan
    • Journal of the Korean Magnetic Resonance Society
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    • v.24 no.1
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    • pp.30-37
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    • 2020
  • Quantitative nuclear magnetic resonance (qNMR) has been gaining attention as a purity assessment method. In particular, qNMR is recognized as the primary method to realize the Internal System of Units (SI) in organic analysis. The capability of quantitative analysis is recognized as the beginning of NMR development. NMR signals are proportional to the number of nuclei and qNMR has been used in various fields, such as metabolomics and food and pharmaceutical analysis. However, careful sample preparation and thorough optimization of measurement parameters are required to obtain accurate and reliable results. In this review, quantitative methods used in qNMR are discussed, and the important factors to be considered also introduced. The recent development of qNMR techniques including combination with chromatography and, multidimensional NMR are also presented.

Performance of Taiwanese Domestic Equity Funds during Quantitative Easing

  • Tan, Omer Faruk
    • The Journal of Asian Finance, Economics and Business
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    • v.2 no.4
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    • pp.5-11
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    • 2015
  • This study is the first to analyze performance of Taiwanese domestic equity funds between January 2009 and October 2014, the period during which quantitative redirected capital flows toward developing economies and the Taiwanese Stock Exchange Weighted Index compounded at approximately 12.9% annually. Adopting methods endorsed by earlier research, we evaluated 15 Taiwanese equity funds' performance relative to market averages using the Sharpe (1966) and Treynor (1965) ratios and Jensen's alpha method (1968). To test market timing proficiency, we applied the Treynor and Mazuy (1966) and Henriksson and Merton (1981) regression analysis methods. Jensen's alpha method (1968) was used to measure fund managers' stock selection skills. Results revealed that funds significantly under-performed Taiwan's average annual market return and demonstrated no exceptional stock-selection skills and market timing proficiency during the era of quantitative easing.

Development of Loss Model Based on Quantitative Risk Analysis of Infrastructure Construction Project: Focusing on Bridge Construction Project (인프라건설 프로젝트 리스크 분석에 따른 손실 정량화 모델 개발 연구: 교량프로젝트를 중심으로)

  • Oh, Gyu-Ho;Ahn, Sungjin
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2022.04a
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    • pp.208-209
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    • 2022
  • This study aims to analyze the risk factors caused by object damage and third-party damage loss in actual bridge construction based on past insurance premium payment data from major domestic insurers for bridge construction projects, and develop a quantitative loss prediction model. For the development of quantitative bridge construction loss model, the dependent variable was selected as the loss ratio, and the independent variable adopted 1) Technical factors: superstructure type, foundation type, construction method, and bridge length 2) Natural hazards: flood anf Typhoon, 3) Project information: total construction duration, total cost and ranking. Among the selected independent variables, superstructure type, construction method, and project period were shown to affect the ratio of bridge construction losses, while superstructure, foundation, flood and ranking were shown to affect the ratio of the third-party losses.

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Quantitative Analysis of Quality Control of Natural Medicine by $^1H-NMR$ Spectrometry-Quantitative Analysis of Hesperidin from Citrus unshiu ($^1H-NMR$을 이용한 한약재의 품질 평가 방법 확립;진피의 Hesperidin 정량분석)

  • Ahn, Eun-Mi;Baek, Mi-Young
    • The Korea Journal of Herbology
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    • v.23 no.3
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    • pp.27-32
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    • 2008
  • Objectives : In this paper, we describe that $^1H-NMR$ spectroscopy may be superior to the conventional HPLC for the quantitative analysis of hesperidin from Citrus unshiu. Methods : $^1H-NMR$ spectra (400 MHz) were recorded in $DMSO-d_6$ using a Varian UNITY Inova AS 400 FT NMR spectrometer. One hundred milligram of powdered Citrus unshiu was weighed out and mixed with 1 ml of $DMSO-d_6$ with sonication for 30 min (room temperature). The extracts were filtrated through a 0.45 ${\mu}m$ PVDF filter and 0.5 ml of filtrated extract used for quantitative $^1H-NMR$ measurement (added 1 mg of dimethyl terephthalate as internal standard). The quantity of hesperidin was calculated by the ratio of the intensity of the compound to the known amount of internal standard. For HPLC analysis, the half gram of plant material was extracted with 60 ml of MeOH for 2 hours. The extracts were made 100 ml volume and analyzed by a Waters HPLC system using a YMC ODS column. The total flow rate was 1.0 ml/min with a sample volume 10 ${\mu}l$ and UV detection at 280nm. Results : The contents of hesperidin in Citrus unshiu was determined $5.33{\pm}0.06$% in the quantitative $^1H-NMR$ method and $5.15{\pm}0.12%$ in HPLC method. Using the quantitative $^1H-NMR$ the contents of hesperidin can be determined in much shorter time than the conventional HPLC measurements. Conclusions : From those results, the advantages of quantitative $^1H-NMR$ analysis are that can be analyzed to identify and quantify, and no reference compounds required for calibration curve. Besides, it allows rapid and simple quantification for hesperidin with an analysis time for only 10 min without any pre-purification steps.

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