• Title/Summary/Keyword: Quantitative Assessments

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Application of Quantitative Assessment of Coronary Atherosclerosis by Coronary Computed Tomographic Angiography

  • Su Nam Lee;Andrew Lin;Damini Dey;Daniel S. Berman;Donghee Han
    • Korean Journal of Radiology
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    • v.25 no.6
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    • pp.518-539
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    • 2024
  • Coronary computed tomography angiography (CCTA) has emerged as a pivotal tool for diagnosing and risk-stratifying patients with suspected coronary artery disease (CAD). Recent advancements in image analysis and artificial intelligence (AI) techniques have enabled the comprehensive quantitative analysis of coronary atherosclerosis. Fully quantitative assessments of coronary stenosis and lumen attenuation have improved the accuracy of assessing stenosis severity and predicting hemodynamically significant lesions. In addition to stenosis evaluation, quantitative plaque analysis plays a crucial role in predicting and monitoring CAD progression. Studies have demonstrated that the quantitative assessment of plaque subtypes based on CT attenuation provides a nuanced understanding of plaque characteristics and their association with cardiovascular events. Quantitative analysis of serial CCTA scans offers a unique perspective on the impact of medical therapies on plaque modification. However, challenges such as time-intensive analyses and variability in software platforms still need to be addressed for broader clinical implementation. The paradigm of CCTA has shifted towards comprehensive quantitative plaque analysis facilitated by technological advancements. As these methods continue to evolve, their integration into routine clinical practice has the potential to enhance risk assessment and guide individualized patient management. This article reviews the evolving landscape of quantitative plaque analysis in CCTA and explores its applications and limitations.

Micromechanics based Models for Pore-Sructure Formation and Hydration Heat in Early-Age Concrete (초기재령 콘크리트의 세공구조 형성 및 발영특성에 관한 미시역학적 모델)

  • 조호진;박상순;송하원;변근주
    • Proceedings of the Korea Concrete Institute Conference
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    • 1999.04a
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    • pp.123-128
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    • 1999
  • Recently, as a performance based design concept is introduced, assurance of expected performances on serviceability and safety in the whole span of life is exactly requested. So, quantitative assessments about durability related properties of concrete in early-age long term are come to necessary, Especially in early age, deterioration which affects long-term durability performance can be occurred by hydration heat and shrinkage, so development of reasonable hydration heat model which can simulate early age behavior is necessary. The micor-pore structure formation property also affects shrinkage behavior in early age and carbonations and chloride ion penetration characteristic in long term, So, for the quantitative assessment on durability performance of concrete, modelings of early age concrete based on hydration process and micor-pore structure formation characteristics are important. In this paper, a micromechanics based hydration heat evolution model is adopted and a quantitative model which can simulate micro-pore structure development is also verified with experimental results. The models can be used effectively to simulate the early-age behavior of concrete composed of different mix proportions.

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Quantitative Analysis of Actigraphy in Sleep Research (수면연구를 위한 액티그라피 정량분석 방법론)

  • Kim, Jong Won
    • Sleep Medicine and Psychophysiology
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    • v.23 no.1
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    • pp.10-15
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    • 2016
  • Since its development in the early 70s, actigraphy has been widely used in sleep research and clinical sleep medicine as an assessment tool of sleep and sleep-wake cycles. The validation and reliability of actigraphic measures have been reasonably examined in healthy normal individuals with good sleep patterns. Recent literature suggests that the use of actigraphy could be further extended to monitor insomnia and circadian sleep-wake disturbances, and detect sleep changes associated with drug treatments and non-pharmacologic interventions, although it is generally recommended to use complementary assessments such as sleep diaries and overnight polysomnography when possible. The development of actigraphy includes its improved hardware sensors for better detection of movements and advanced algorithms to score sleep and wake epochs. In this paper, we briefly review the quantitative analysis methods of actigraphy and its potential applications in sleep research.

Development of a Three-Dimensional Chemotaxis Model for a Single Bacterium (3 차원 모델을 통한 단일 박테리아의 주화성 연구)

  • Song, Ji-Hwan;Kim, Dong-Choul
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.33 no.1
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    • pp.56-63
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    • 2009
  • Cell migration is one of the essential mechanisms responsible for complex biological processes. Intensive researches have begun to elucidate the mechanisms and search intriguing conditions for efficient control of cell migration. One general mechanism that is widely applicable for cells including Escherichia coli, amoebae and endothelial cell is chemotaxis. The single cell study for bacterial chemotaxis has an advantage over studies with the population of cells in providing a clearer observation of cell migration, which leads to more accurate assessments of chemotaxis. In this paper, we propose a three-dimensional model considering a single bacterium to study its chemotaxis. The semi-implicit Fourier spectral method is applied for high efficiency and numerical stability. The simulation results reveal rich dynamics of cell migration and provide quantitative assessments of bacterial chemotaxis with various chemoattractant gradient fields.

Construction Safety Risk Assessment Method Based on Accident Loss Cost in the Construction Phase (시공단계의 사고손실 비용 기반 건설안전 위험성 평가 방안)

  • Lee, Jae-Hyun;Jeong, Jae-Wook;Jeong, Jae-Min
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2023.05a
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    • pp.407-408
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    • 2023
  • This article proposes a method to assess construction safety risk during the construction phase based on accident loss costs. Risk assessments for hazardous construction work are required by law, but they lack quantitative criteria. To address this, a survey estimated loss costs due to fatalities in the construction industry, finding labor loss cost and delay reimbursement cost to be the largest factors. The proposed method uses algorithm to calculate expected accidents and risk levels based on project characteristics, work methods, personnel, and environment data. This method is expected to enhance the reliability and usability of risk assessments during the construction phase of construction projects.

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Cheese Microbial Risk Assessments - A Review

  • Choi, Kyoung-Hee;Lee, Heeyoung;Lee, Soomin;Kim, Sejeong;Yoon, Yohan
    • Asian-Australasian Journal of Animal Sciences
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    • v.29 no.3
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    • pp.307-314
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    • 2016
  • Cheese is generally considered a safe and nutritious food, but foodborne illnesses linked to cheese consumption have occurred in many countries. Several microbial risk assessments related to Listeria monocytogenes, Staphylococcus aureus, and Escherichia coli infections, causing cheese-related foodborne illnesses, have been conducted. Although the assessments of microbial risk in soft and low moisture cheeses such as semi-hard and hard cheeses have been accomplished, it has been more focused on the correlations between pathogenic bacteria and soft cheese, because cheese-associated foodborne illnesses have been attributed to the consumption of soft cheeses. As a part of this microbial risk assessment, predictive models have been developed to describe the relationship between several factors (pH, Aw, starter culture, and time) and the fates of foodborne pathogens in cheese. Predictions from these studies have been used for microbial risk assessment as a part of exposure assessment. These microbial risk assessments have identified that risk increased in cheese with high moisture content, especially for raw milk cheese, but the risk can be reduced by preharvest and postharvest preventions. For accurate quantitative microbial risk assessment, more data including interventions such as curd cooking conditions (temperature and time) and ripening period should be available for predictive models developed with cheese, cheese consumption amounts and cheese intake frequency data as well as more dose-response models.

EVALUATION OF HAIR DAMAGE BASED ON MEASUREMENTS OF LABILE PROTEIN

  • Inoue, Takafumi;Ito, Mayumi;Kizawa, Kenji;Iwamoto, Yoshimichi
    • Proceedings of the SCSK Conference
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    • 2003.09a
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    • pp.142-160
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    • 2003
  • Most consumers have noted hair damage following coloring treatments. Proper evaluation of hair bleaching products must be performed using quantitative assessments of hair damage, though they are difficult, because of the slight fluctuations in hair composition. In the present study, we utilized a sensitive evaluation method for hair damage and found that the amount of soluble protein fraction extracted from hair under a reducing condition, termed labile protein, dramatically increased after bleaching.(omitted)

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Procedure of Quantitative Safety Assessment for Risk Management System (위험관리시스템 구축을 위한 정량적 안전평가 절차)

  • Jung, Won
    • Journal of Applied Reliability
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    • v.9 no.3
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    • pp.165-176
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    • 2009
  • The risk management case is an organization's formal arrangement to ensure the safety of its work activity within risk management system. It allows an organization to demonstrate its capability in achieving its safety objectives and in meeting regulatory requirements. This paper presents how the safety assessments are described, prepared and maintained to meet the criteria specified by the upcoming safety regulations. We propose the elements of risk management system that include arrangements for the ongoing identification of hazards, assessment of risks and the implementation of necessary control measures.

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A Study on a Efficiency of Glazing for Energy Reduction of Curtain Wall Buildings (유리성능에 따른 커튼월건물의 에너지절약효과에 대한 연구 -표준건물 에너지소비와의 비교분석을 중심으로-)

  • Lee, Yong-Jun;Jung, Kwang-Sub;Oh, Bo-Hwan;Kang, Jae-Sik;Choi, Kyoung-Suk;Lee, Deuk-Ho
    • Proceedings of the SAREK Conference
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    • 2009.06a
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    • pp.114-119
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    • 2009
  • This study has been conducted to describe the establishment of national measures to reduce world energy consumption and $CO_2$ Emission. Particularly, Reductions in energy consumption from building operation is the most important part to achieve these national objectives. Element to evaluate the quantitative effects of these systems by having rationalized regulation and operation is essential, when planning for building energy reduction design. USGBC(US Green Building Council) have operated sustainable assessment method called LEED, which introduces baseline performance and evaluation direction for building simulation techniques. This research analyzed Quantitative assessments of the building energy consumption and analyzed baseline figures to provide comparative analysis with standard building settings.

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Quantitative analysis for evaluating the laser therapy effects of the skin pigmented lesions (피부 색소 질환의 치료 효과 판정을 위한 정량적 분석)

  • Kim, S.C.;Rah, D.K.;Kim, D.W.
    • Proceedings of the KOSOMBE Conference
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    • v.1998 no.11
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    • pp.309-310
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    • 1998
  • Visual observation and subjective assessments lack the objective evaluation of laser therapy effects of the epidermal pigmented lesions. In this study, we proposed the two methods; One is CIE(Commission International d'Eclairage) $L^*,\;a^*,\;b^*$ coordinate system($L^*$ : brightness, $a^*$ : red(+) $\sim$green(-) content, $b^*$ : yellow(+) $\sim$blue(-) content), and the other is the relative color difference measurement. And we applied these two methods for quantitative evaluation of the laser therapy effects.

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