• Nuclear Medicine and Molecular Imaging
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• v.40 no.2
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• pp.96-105
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• 2006

Molecular imaging has its root in nuclear medicine and gene therapy monitoring. Therefore, recent progress in the development of non-invasive imaging technologies, particularly nuclear medicine, should allow molecular imaging to play a major role in the field of gene therapy. These tools have recently been validated in gene therapy models for continuous quantitative monitoring of the location, magnitude, and time-variation of gene delivery and/or expression. This article reviews the use of radionuclide imaging technologies as they have been used in imaging gene delivery and gene expression for gene therapy applications. The studios published to date lend support that noninvasive imaging tools will help to accelerate pre-clinical model validation as well as allow for clinical monitoring of human gene therapy.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.8 no.11
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• pp.1-16
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• 1985

This study is to systematize a flow of production activities with a formula to help understand the trend of production in an enterprise according to the profit graph. Although the existing methods of studies were unattainable to analyze earnings correlative to production due to the lack of total business management, this study is aimed at testing a new method that developed the method of an advanced analysis as well as a combined system of the profit graph. and the production trend.

• Molecules and Cells
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• v.42 no.3
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• pp.189-199
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• 2019

Cell-to-cell variability in gene expression exists even in a homogeneous population of cells. Dissecting such cellular heterogeneity within a biological system is a prerequisite for understanding how a biological system is developed, homeostatically regulated, and responds to external perturbations. Single-cell RNA sequencing (scRNA-seq) allows the quantitative and unbiased characterization of cellular heterogeneity by providing genome-wide molecular profiles from tens of thousands of individual cells. A major question in analyzing scRNA-seq data is how to account for the observed cell-to-cell variability. In this review, we provide an overview of scRNA-seq protocols, computational approaches for dissecting cellular heterogeneity, and future directions of single-cell transcriptomic analysis.

• Journal of Information Processing Systems
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• v.15 no.2
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• pp.399-409
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• 2019

Three-dimensional (3D) human pose reconstruction from single-view image is a difficult and challenging topic. Existing approaches mostly process frame-by-frame independently while inter-frames are highly correlated in a sequence. In contrast, we introduce a novel spatial-temporal 3D human pose reconstruction framework that leverages both intra and inter-frame relationships in consecutive 2D pose sequences. Orthogonal matching pursuit (OMP) algorithm, pre-trained pose-angle limits and temporal models have been implemented. Several quantitative comparisons between our proposed framework and recent works have been studied on CMU motion capture dataset and Vietnamese traditional dance sequences. Our framework outperforms others by 10% lower of Euclidean reconstruction error and more robust against Gaussian noise. Additionally, it is also important to mention that our reconstructed 3D pose sequences are more natural and smoother than others.

• ETRI Journal
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• v.43 no.4
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• pp.594-602
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• 2021

Recently, quantitative and repetitive inspections of the old urban area were conducted because many structures exceed their designed lifetime. The health of a building can be validated from the condition of the outer wall, while the slant angle of the wall widely serves as an indicator of urban regeneration projects. Mostly, the inspector directly measures the inclination of the wall or partially uses 3D point measurements using a static light detection and ranging (LiDAR). These approaches are costly, time-consuming, and only limited space can be measured. Therefore, we propose a mobile mapping system and automatic slant map generation algorithm, configured to capture urban environments online. Additionally, we use the LiDAR-inertial mapping algorithm to construct raw point clouds with gravity information. The proposed method extracts walls from raw point clouds and measures the slant angle of walls accurately. The generated slant angle map is evaluated in indoor and outdoor environments, and the accuracy is compared with real tiltmeter measurements.

• Computers and Concrete
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• v.24 no.5
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• pp.469-488
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• 2019

In this research study, the artificial neural networks approach is used to estimate the ultimate shear capacity of reinforced concrete beams with transverse reinforcement. More specifically, surrogate approaches, such as artificial neural network models, have been examined for predicting the shear capacity of concrete beams, based on experimental test results available in the pertinent literature. The comparison of the predicted values with the corresponding experimental ones, as well as with available formulas from previous research studies or code provisions highlight the ability of artificial neural networks to evaluate the shear capacity of reinforced concrete beams in a trustworthy and effective manner. Furthermore, for the first time, the (quantitative) values of weights for the proposed neural network model, are provided, so that the proposed model can be readily implemented in a spreadsheet and accessible to everyone interested in the procedure of simulation.

• The Journal of Asian Finance, Economics and Business
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• v.8 no.4
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• pp.717-726
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• 2021

Tourism is one of the key economic drivers not only in Vietnam but also in the world. This study explores the awareness and perceptions of key stakeholders such as local residents, tourism businesses, and tourists on sustainable tourism development in the Mekong Delta in Vietnam. Both quantitative and qualitative research approaches have been used with the secondary and primary data to provide insights on the subject. The secondary data is from vast sources, including the governmental department of tourism, statistical departments, annual all-level governmental reports, businesses, and others. The primary data is from the survey by questionnaires with 230 enterprises, 720 local residents, and 670 tourists and from the semi-structured and in-depth interviews conducted with local residents, businesses, tourists, local authorities' officers, and especially with 5 experts who are also stakeholders of Mekong Delta tourism. The results will help the related authorities understand the awareness and perceptions of the key stakeholders and deliver valuable information and a concrete delineated roadmap toward sustainable tourism development of the research settings.

• The Korean Journal of Physiology and Pharmacology
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• v.25 no.1
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• pp.1-14
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• 2021

Cardiovascular disease (CVD) accounts for approximately 30% of all deaths worldwide and its prevalence is constantly increasing despite advancements in medical treatments. Cardiac remodeling and dysfunction are independent risk factors for CVD. Recent studies have demonstrated that cardiac structure and function are genetically influenced, suggesting that understanding the genetic basis for cardiac structure and function could provide new insights into developing novel therapeutic targets for CVD. Regular exercise has long been considered a robust nontherapeutic method of treating or preventing CVD. However, recent studies also indicate that there is inter-individual variation in response to exercise. Nevertheless, the genetic basis for cardiac structure and function as well as their responses to exercise training have yet to be fully elucidated. Therefore, this review summarizes accumulated evidence supporting the genetic contribution to these traits, including findings from population-based studies and unbiased large genomic-scale studies in humans.

• Journal of information and communication convergence engineering
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• v.18 no.4
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• pp.230-238
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• 2020

This study aims to determine whether student participation on Twitter affects academic performance. The key goals of the training course were to acquire social networking knowledge and skills and to learn how to share information, be productive in discussions, and create an interest-based community. The initial sample comprised 286 students from Jordan universities, 68.4% of whom agreed to participate in the study. Undergraduate students accounted for 73.9%, and graduate students accounted for 26.1%. Only 14.3% of the students chose the Twitter-based learning model. This is a mixed-methods study that integrates quantitative and qualitative approaches. The undergraduate students were found to tweet more and have more likes, while graduate students had more followers and were following more accounts. Moreover, 21% of the participants were the most active. Spearman's correlation analysis revealed a connection between participation in social media and student performance. Therefore, the results of this study may help educational professionals and education managers.

• International Journal of Computer Science & Network Security
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• v.22 no.8
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• pp.217-221
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• 2022

The article analyzes the main theoretical approaches to the formation of managerial competencies and establishes the degree of development of the problem. The content of the concept of "managerial competence" has been clarified, to determine the structure of managerial competencies of a future specialist in the education system and indicators of the formation of managerial competencies. The organizational and pedagogical conditions necessary for the effective process of forming the managerial competencies of future specialists are revealed. The following research methods were used in the work: theoretical (analysis of regulatory documents and scientific literature on the problem under study, comparison, generalization, modeling), empirical (diagnostics of the level of formation of managerial competencies of students of the system, questioning, observation, peer review, comparative qualitative and quantitative analysis of diagnostic results the level of formation of managerial competencies).