• Journal of the Korean Recycled Construction Resources Institute
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• v.7 no.3
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• pp.194-201
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• 2019

This study analyzed the properties of concrete depending on the coal gasification slag(CGS) contents in order to examine the applicability of CGS as the fine aggregate for concrete. Experimental results, trended that the slump and slump flow increased with increasing CGS contents, and air contents has decreased. Evaluation index for segregation of normal strength concrete(EISN) is showed was good from CGS 25% when using crushed sand A(CSa) and CGS 50% when using mixed sand(MS). The compressive strength decreased with increasing CGS contents when CSa was used. However, when MS was used, the maximum value was CGS 50% due to parabolic tendency. Depending on fine aggregates type, compared with compressive strength of CSa was about 8% higher than that of MS, and depending on the use or unuse of CGS, more advantageous at higher strength than low strength. As a result of relative performance study on the quality of concrete according to the CGS contents, it is considered that CGS can be positively contributed to enhancement of workability and strength development when mixed with fine aggregate around 25~50%.

• Journal of Biomedical Engineering Research
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• v.40 no.5
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• pp.197-205
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• 2019

The existing Extracorporeal membrane oxygenation(ECMO) and Cardiopulmonary bypass system(CPB) have been developed and applied to various devices according to their respective indications. However, due to the complicated configuration and difficult usage method, it causes inconvenience to users and there is a risk of an accident. Therefore, smart all-in-one cardiopulmonary circulation device is being developed recently. The smart all-in-one cardiopulmonary assist device consists of a blood pump for cardiopulmonary bypass, a blood oxidizer for cardiopulmonary bypass, a blood circuit for cardiopulmonary bypass, and an artificial cardiopulmonary device. It is an integrated cardiopulmonary bypass device that can be used for a variety of purposes such as emergency, intraoperative, post-operative intensive care, and long-term cardiopulmonary assist, combined with CPB used in open heart surgery and ECMO used when patient's cardiopulmonary function does not work normally. The smart all-in-one cardiopulmonary assist device does not exist as a standard and international standard applicable to advanced medical devices. Therefore, in this study, we will refer to the International Standard for Blood Components, the International Standard for Blood, the Guideline for Blood Products, and prepare applicable performance and safety guidelines to help quality control of medical devices, and contribute to the improvement of the health of people. The guideline, which is the result of conducted a survey of the method of safety and performance test, is based on the principle of all-in-one cardiopulmonary aiding device, related domestic foreign standards, the status of domestic and foreign patents, related literature, blood pump(ISO 18242), blood oxygenator (ISO 7199), and blood circuit (ISO 15676) for cardiopulmonary bypass.The items on blood safety are as follows: American Society for Testing and Materials ASTM F1841-97R17), and in the 2010 Food and Drug Administration's Safety Assessment Guidelines for Medical Assisted Circulatory Devices. In addition, after reviewing the guidelines drawn up through expert consultation bodies including manufacturers / importers, testing inspectors, academia, etc. the final guideline was established through revision and supplementation process. Therefore, we propose guidelines for evaluating the safety and performance of smart all-in-one cardiopulmonary assist devices in line with growing technology.

• Proceedings of the Korea Water Resources Association Conference
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• 2016.05a
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• pp.510-510
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• 2016

농업 비점오염원의 영향을 분석하고 여러 가지 대안(관리정책)이 수계의 수질에 미치는 영향을 평가하기 위해서 유역모형의 적용이 필요하다. 이러한 유역모형에는 모형의 복합성, 계산시간 등에 따라 simple method, mid-range model, detail model로 나눌 수 있다. Simple methods는 요구되는 자료가 작으나 그 결과의 정확성은 떨어진다. 반면에 detail model는 정확한 결과를 획득할 수 있으나 그만큼 방대한 자료와 모니터링을 요구하며, 보정 및 검증에 많은 시간과 노력을 필요로 한다. 특히, 복잡한 유역특성 및 축산오염원을 포함한 복잡한 특성들을 고려해서 모델링하기 위해서는 detail model이 필요하며 본 연구에서는 HSPF모델을 이용해서 그 영향을 분석하고자 하였다. 따라서 본 연구에서는 농업에 미치는 영향을 평가하기 위해서 청미천 유역 및 덕천천 유역을 대상유역으로 선정하여 그 영향을 분석하였다. 농업에 미치는 영향을 평가하기 위해서 유역내 투입된 비료사용량을 통계청 자료를 활용하여 산정후 적용하였으며, 축산 부산물중 자원화되는 축산 액비 및 퇴비량을 산정하여 그 영향에 대해 분석하였다. 또한 기존에 광범위하게 활용되고 있는 수질오염총량관리제도에서 산정되는 배출부하량에 유달율을 고려하여 점오염으로 입력하였으며, 직접방류되는 하수처리장도 함게 고려하여 구축하였다. 청미천 유역의 청미천1 지점의 BOD, T-N, T-P에 대한 보정기간의 평균 관측값은 4.205mg/L, 3.844mg/L, 0.137mg/L이며 검정기간의 관측값은 2.741mg/L, 4.638mg/L, 0.144mg/L로 나타났다. BOD, T-N, T-P에 대한 보정기간의 NSE는 -0.58, -0.20, -0.33이며, 검정기간의 NSE는 -0.26, -1.35, -3.54로 분석되었다. BOD, T-N, T-P에 대한 보정기간의 RMSE는 2.65, 1.63, 0.12이며, 검정기간의 RMSE는 1.36, 1.64, 0.07로 나타났다. 덕천천 유역의 경우 국가관측망이 없어 동진강의 제일 말단 지점인 동진강3 지점의 BOD, T-N, T-P에 대한 보정기간 평균관측값은 2.891mg/L, 3.455mg/L, 0.096mg/L이며, 검정기간의 관측값은 2.293mg/L, 3.223mg/L, 0.104mg/L로 나타났다. BOD, T-N, T-P에 대한 보정기간의 NSE는 -0.20, -0.56, -0.49이며, 검정기간의 NSE는 0.24, -0.06, -0.19으로 분석되었다. BOD, T-N, T-P에 대한 보정기간의 RMSE는 1.53, 2.12, 0.05이며, 검정기간의 RMSE는 1.05, 0.98, 0.06으로 나타났다. 본 연구의 분석결과는 점오염원, 축산계비점오염, 토지계비점오염, 시비량, 배경부하로 구분하여 분석을 실시하였으며 분석결과 청미천 유역의 비점오염 기여율이 약 65%를 차지하고 있는 것으로 평가되었으며, 덕천천 말단에서는 약 37.7%의 비점오염물질이 하천수질에 영향을 미치는 것으로 나타났다. 또한, 기존 수질오염 총량관리제도에서 점오염의 감소에 의한 비점오염비중이 커지는 것으로 평가되었으며, 그 중 축산이 차지하는 비중이 상대적으로 높은 것으로 평가되고 있지만, 본 연구의 결과에서는 그보다 적은 수준이 수계에 영향을 미치는 것으로 분석되었다.

• Journal of Microbiology and Biotechnology
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• v.29 no.10
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• pp.1495-1505
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• 2019

The Burkholderia cepacia complex (BCC) is capable of remaining viable in low-nutrient environments and harsh conditions, posing a contamination risk in non-sterile pharmaceutical products as well as a challenge for detection. To develop optimal recovery methods to detect BCC, three oligotrophic media were evaluated and compared with nutrient media for the recovery of BCC from autoclaved distilled water or antiseptic solutions. Serial dilutions ($10^{-1}$ to $10^{-12}CFU/ml$) of 20 BCC strains were inoculated into autoclaved distilled water and stored at $6^{\circ}C$, $23^{\circ}C$ and $42^{\circ}C$ for 42 days. Six suspensions of Burkholderia cenocepacia were used to inoculate aqueous solutions containing $5{\mu}g/ml$ and $50{\mu}g/ml$ chlorhexidine gluconate (CHX) and $10{\mu}g/ml$ benzalkonium chloride (BZK), and stored at $23^{\circ}C$ for a further 199 days. Nutrient media such as Tryptic Soy Agar (TSA) or Tryptic Soy Broth (TSB), oligotrophic media (1/10 strength TSA or TSB, Reasoner's $2^{nd}$ Agar [R2A] or Reasoner's $2^{nd}$ Broth [R2AB], and 1/3 strength R2A or R2AB) were compared by inoculating these media with BCC from autoclaved distilled water and from antiseptic samples. The recovery of BCC in water or antiseptics was higher in culture broth than on solid media. Oligotrophic medium showed a higher recovery efficiency than TSA or TSB for the detection of 20 BCC samples. Results from multiple comparisons allowed us to directly identify significant differences between TSA or TSB and oligotrophic media. An oligotrophic medium pre-enrichment resuscitation step is offered for the United States Pharmacopeia (USP) proposed compendial test method for BCC detection.

• Journal of Integrative Natural Science
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• v.4 no.1
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• pp.38-43
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• 2011

The recent global warming may be estimated to give lots of impacts to the human society and biosphere of influencing climate change included by the natural climate variations through the human activity which can directly and/or indirectly play a major role of total atmospheric composition overall. Therefore it currently appears evidences such as hot wave, typhoon, and biosphere disturbance, etc. over the several regions to be influenced by global warming due to increasing the concentration of greenhouse gases in the atmosphere through inducing forest destruction, fossil fuel combustion, greenhouse gases emission, etc. since industrial revolution era. Through the working group report of IPCC (Intergovernmental Panel on Climate Change) for climate change was analyzed by the individual country's current status and figure out the important issues and problems related to the future trend of climate change science with advanced countries preparedness and research, In this study, the first working group report of IPCC focuses on those aspects of the current understanding of the physical science of climate change that are judged to be most relevant to policymakers. As this report was assessed and analyzed by including the progress of climate change science, the role of climate models and evolution in the treatment of uncertainties. This consists of the changes in atmospheric constituents(both aerosols and gases) that affect the radiative energy balance in the atmosphere and determine the Earth's climate, considering the interaction between biogeochemical cycles that affect atmospheric constituents and climate change, including aerosol/cloud interactions, the extensive range of observations snow available for the atmosphere and surface, for snow, ice, and frozen ground and for the oceans, respectively and changes in sea level, the paleoclimate perspective and assessment of evidence for past climate change and the extension, the ways in which physical processes are simulated in climate models and the evaluation of models against observed climate, the development plans and methods of improving expert and building manpower urgently and R&D fund expansion in detail for climate change science in Korea will be proposed.

• Korea journal of population studies
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• v.11 no.1
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• pp.14-31
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• 1988

The national family planning program in Korea, which was instituted as an integral part of the nation's economic development plans since 1962, has contributed greatly to a reduction in the fertility and population growth rate. The total fertility rate dipped from 6.0 births per women in 1960 to 2.0 in 1985, and the population growth rate rom 2.84 percent per year to 1.25 percent during the same period, while the contraceptive practice rate for the 15-44 married women increased from 9 percent in 1965 to 70 percent in 1985. Study findings indicate that the fertility reduction in the past 26 years is largely attributed to the virgorous implementation of the national family planning program, rising age at marriage, wide-spread use of induced abortion, and the changes in attitude regarding the value of children that came into being in the wake of the rapid socio-economic development over the period. Among the strengths of the national family planning program are the following : 1) a pluralistic system of program manageent with active participation of various government and voluntary organizations, 2) utilization of a large corps of family planning field workers to conduct face-to-face communication and motivation activities, 3) use of private physicians with government support to provide contraceptive services, 4) a systematic program management system including program planning of traget allocation, evaluation, and supervision with a broad MIS and award system, 5) numerous incentive and disincentive schemes for stimulating the small family norm and contraceptive use, and 6) strong commitments to the family planning program by political leaders. The new demographic targets during the Sixth Five-Year Economic and Social Development plan period(1987-91) have been set for a further reduction in the population growth rate to 1.0 percent by 1993, assuming that the TFR will decline to 1.75 level in 1995. This target is, however, not easy to achieve due to anticipated unfavorable factors like the strong boy preference, high discontinuation rates of reversible contraceptive methods, fertility termination-oriented contraceptive use, a plateau level of contraceptive practice rate that has mostly accounted for a sterilization, shortened length of birth intervals, and the changing patterns of contraceptive mix. The recent changes in contraceptive and fertility behaviors clearly indicate that the past quantity-oriented management system of the national program should be redirected toward a quality-oriented approach. Particularly, program efforts should be expanded to recruit new contraceptive users in the 20s of younger age groups, both for birth spacing and controlling their fertility since the women aged 20 to 29 account for more than 80 percent of the total annual births in recent years. In addition, the current contraceptive fee system of the national family planning program should be gradually shifted from free contraceptive services to a acceptor's charge system, and the provision of contraceptive services through the medical insurance system, which will cover the entire population by 1989, should be accelerated as a means of integration of family planning program with other health programs.

• Food Science and Preservation
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• v.18 no.6
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• pp.836-843
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• 2011

The purpose of this study was to develop a functional hasuo (Polygoni Multiflori Radix) muffin prepared via the replacement of sucrose (SM) with oligosaccharide (fructooligosaccharide, isomaltooligosaccharide, galactooligosaccharide). The fructooligosaccharide-added hasuo muffin showed the highest weight while the volume and specific volume were lower in the oligosaccharide-added group than in the sucrose-added sample. The pH of the sucrose-added sample was higher than that of the oligosaccharide-added sample. The lowest lightness value was found in the sucrose-added sample, but the highest redness and yellowness values were found in the sucrose-added sample. The springiness and cohesiveness were highest in the fructooligosaccharide-added sample. The DPPH-radical-scavenging activity of the hasuo muffin including sucrose was 38.67, while that including the oligosaccharide group ranged from 42.87 to 65.95. In the sensory evaluation of the hasuo muffin, the fructooligosaccharide-added sample obtained the highest score in after-swallow, flavor, taste, and texture. The hasuo muffin with fructooligosaccharide and isomaltooligosaccharide obtained high scores in overall acceptability. These results suggest that hasuo muffin with fructooligosaccharide and isomaltooligosaccharide have the potential to become commercially successful muffins.

• Food Science and Preservation
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• v.18 no.6
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• pp.891-897
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• 2011

Oak barrel have been used for a long time for the aging of wine. Instead of oak barrel aging, however, roasted oak chips can be directly added in the wine before aging. In this study, Korean oak chips roasted for different time durations were used for the red wine aging, and the properties of wine aged through the addition of the roasted oak chips were characterized. No significant differences were observed in the alcohol, soluble-solid, reducing-sugar and total-acid contents based on the oak chips aging, but the total phenol content increased. The methanol, ethyl acetate, propanol, isobutanol and isoamyl alcohol contents also increased. Especially, the methanol and propanol contents increased as the roasting time was prolonged. Although the hue values were similar to one another, the intensity as well as the lightness, redness, and yellowness values were high in the wine aged with the roasted oak chips. In the sensory evaluation, the wine aged with oak chips roasted for 2 h showed the highest scores in the flavor, taste, and overall preference.

• Journal of Fisheries and Marine Sciences Education
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• v.26 no.6
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• pp.1231-1244
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• 2014

Oysters, especially are excellent source of several mineral including iron, zinc and selenium, which are often low in the mordern diet. They are also an excellent source of glycogen, vitamin B12 and considered the healthiest when eaten raw on the half shell in good tasted season from November to March. This study was investigated for the purpose of obtaining basic data which can be applied to processing of two kinds of canned boiled oyster (canned boiled oyster, canned boiled oyster in bamboo salt). Shucked oyster meat was cooked in steam (15min) after washing with water, filled 90g into can (301-3), added with salt solution and then precooked for 10 min. at $100^{\circ}C$. Canned boiled oyster was added 1.5% salt solution 60mL. Canned boiled oyster in bamboo salt was added 0.5% salt solution 30mL and 0.7% bamboo salt solution 30mL. The cans were seamed using a vacuum seamer, and then sterilized for various Fo values (Fo 8~12 min.) in a steam system retort at $116^{\circ}C$, $118^{\circ}C$. Viable bacterial count, proximate composition, pH, salinity, yield, VBN, amino-N, TBA, mineral, color value, free amino acid, hardness and sensory evaluation of two kinds of canned boiled oyster produced at various sterilization condition (Fo 8~12 min.) were measured after divide to meat and juice. The results showed that canned boiled oyster in bamboo salt sterilized at Fo 8 min. was the most desirable because this condition is the most economical and tasty.

• Journal of Soil and Groundwater Environment
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• v.19 no.4
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• pp.62-69
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• 2014

In the results of monitoring nitrate concentration in more than 8,000 groundwater wells around agro-livestock, the average and maximum nitrate concentration was 9.4 mg/L and 101.2 mg/L, respectively. Since about 31% of the monitoring wells was exceed the quality standard for drinking water, nitrate control such as remediation or source regulation is required to conserve safe-groundwater in South Korea. Typical nitrate-treatment technologies include ion exchange, reverse osmosis, and biological denitrification. Among the treatment methods, biological denitrification by indigenous microorganism has environmental and economic advantages for the complete elimination of nitrate because of lower operating costs compared to other methods. Major mechanism of the process is microbial reduction of nitrate to nitrite and nitrogen gas. Three functional genes (nosZ, nirK, nirS) that encode for the enzyme involved in the pathway. In this work, we tried to develop simple process to determine possibility of natural denitrification reaction by monitoring the functional gene. For the work, the functional genes in nitrate-contaminated groundwater were monitored by using PCR with specific target primers. In the result, functional genes (nosZ and nirK) encoding denitrification enzymes were detected in the groundwater samples. This method can help to determine the possibility of natural-nitrate degradation in target groundwater wells without multiplex experimental process. In addition, for field-remediation application we selected nitrate-contaminated site where 200~600 mg/L of nitrate is continuously detected. To determine the possibility of nitrate-degradation by stimulated-natural attenuation, groundwater was sampled in two different wells of the site and nitrate concentration of the samples was 300 mg/L and 616 mg/L, respectively. Fumarate for different C/N ratio was added into microcosm bottles containing the groundwater to examine denitrification rate depending on carbon concentration. In the result, once 1.5 times more than amount of fumarate stoichiometry required was added, the 616 mg/L of nitrate and 300 mg/L of nitrate were completely degraded in 8 days and 30 days. The nitrite, byproduct of denitrification process, was also completely degraded during the experimental period.