• Korean Journal of Pharmacognosy
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• v.41 no.4
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• pp.313-318
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• 2010

Guibi-tang, a traditional herbal medicine, is used for anti-oxidant, anti-osteoporosis, hemostasis and gastroprotection. To develop an analysis method of simultaneous determination of six compounds, swertisin, decursinol, glycyrrhizin, 6-gingerol, costunolide and decursin in Guibi-tang, a high performance liquid chromatography was used with diode array detector. Six bioactive components were separated on a SHISEIDO $C_{18}$ column ($5\;{\mu}m$, 4.6 mm I.D.${\times}$250 mm) with column temperature $30^{\circ}C$. The gradient elution was composed of water with 0.1% trifluoroacetic acid (TFA) and acetonitrile. UV wavelength was set at 230 nm, 254 nm and 330 nm, respectively. Calibration curve showed good linear regression ($R^2$ > 0.9999). The limits of detection (LOD) and the limits of quantification (LOQ) ranged in 0.03 - 0.23 ${\mu}g/ml$ and 0.08 - $0.70\;{\mu}g/ml$, respectively. The RSD values of intra- and inter-day test were in the range of 0.03 ~ 0.96% and 0.01 ~ 1.46%, respectively. The evaluated results of accuracy test were varied from 92.28% ~ 105.14% with RSD < 1.60%. In conclusion, this developed simultaneous determination method was accuracy and sensitive to the quality evaluation of Guibi-tang.

• Proceedings of the Korean Society of Near Infrared Spectroscopy Conference
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• 2001.06a
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• pp.4104-4104
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• 2001

Milk somatic cell count (SCC) is a recognized indicator of cow health and milk quality. The potential of near infrared (NIR) spectroscopy in the region from 1100 to 2500nm to measure SCC content of cow milk was investigated. A total of 196 milk samples from 7 Holstein cows were collected for 28 days, consecutively, and analyzed for fat, protein, lactose and SCC. Three of the cows were healthy, and the rest had mastitis periods during the experiment. NIR transflectance milk spectra were obtained by the InfraAlyzer 500 spectrophotometer in a wavelength range from 1100 to 2500 nm. The calibration for logSCC was performed using partial least square (PLS) regression and different spectral data pretreatment. The best accuracy of determination was found for equation, obtained using smoothed absorbance data and 10 PLS factors. The standard error of calibration was 0.361, calibration coefficient of multiple correlation 0.868, standard error of prediction for independent validation set of samples 0.382, correlation coefficient 0.854 and the variation coefficient 7.63%. The accuracy of logSCC determination by NIR spectroscopy would allow health screening of cows, and differentiation between healthy and mastitic milk samples. When the spectral information was studied it has been found that SCC determination by NIR milk spectra was indirect and based on the related changes in milk composition. In the case of mastitis, when the disease occurred, the most significant factors that simultaneously influenced milk spectra were alteration of milk proteins and changes in ionic concentration of milk.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.32 no.4
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• pp.43-52
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• 2004

In this paper, the performance of the KOMPSAT-1 orbit determination (OD) accuracy at the ground station was analyzed by using the flight data. The Bayesian least squares estimation was used for the orbit determination and the assessment of the orbit accuracy was evaluated based on orbit overlap comparisons. We also compared the result from OD using GPS navigation solutions with NORAD TLE and the result from OD using range data. Furthermore, the effect of observation type and OBT drift on the accuracy was investigated. As a consequence, It is shown that the OD accuracy using only GPS position data is on the order of 5m RMS (Root Mean Square) with 4 hrs arc overlap for the 30hr arc and the GPS velocity data is not proper as a observation for the OD due to its inferior quality. The significant deterioration of the accuracy due to the critical clock bias was not founded by means of the comparison of OD result from other observations.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.40 no.5
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• pp.171-180
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• 2003

CDMA(Code Division Multiple Access) mobile communication systems require accurate channel estimation in the receiver to compensate the fading distortions. Instantaneous channel estimates are obtained by dividing the received symbol by the transmitted symbol and then refined by filtering to reduce the estimation variance. In the channel estimation filter, the determination of the filter size is a very important task which greatly affects the estimation quality. While conventional methods usually use only velocity estimators to determine the channel estimation filter size, this paper proposes a filter size determination method for decision-directed channel estimators considering the symbol error rate and the signal-to-noise ratio in addition to the velocity of the mobile station. This paper shows that the symbol error rate and the signal-to-noise ratio are important factors for the determination of the channel estimation filter size.

• Aerospace Engineering and Technology
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• v.12 no.2
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• pp.40-47
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• 2013

GEO-KOMPSAT2 shall be designed to produce higher quality of image than that of COMS, and this requires the ground system to provide orbit data with high accuracy; better than 2km which is sort of high accuracy when it comes to geostationary satellite. For GEO-KOMPSAT2, KARI is planning to use ranging data for orbit determination, obtained from two ranging stations located in KARI and oversea country with long longitudinal baseline. This paper estimated achievable orbit determination accuracy using covariance analysis under assumption of using two ranging stations; SOC and available secondary tracking stations located in oversea countries. In addition to covariance analysis, in order to validate the analysis, the Monte-Carlo simulation has been performed and compared to the covariance analysis.

• Journal of Biosystems Engineering
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• v.40 no.4
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• pp.394-408
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• 2015

Spectroscopy is an emerging technology for the quality assessment of pharmaceutical samples, from tablet manufacturing to final quality assurance. The traditional methods for the quality management of pharmaceutical tablets are time consuming and destructive, while spectroscopic techniques allow rapid analysis in a non-destructive manner. The advantage of spectroscopy is that it collects both spatial and spectral information (called hyperspectral imaging), which is useful for the chemical imaging of pharmaceutical samples. These chemical images provide both qualitative and quantitative information on tablet samples. In the pharmaceutics, spectroscopic techniques are used for a variety of applications, such as analysis of the homogeneity of powder samples as well as determination of particle size, product composition, and the concentration, uniformity, and distribution of the active pharmaceutical ingredient in solid tablets. This review paper presents an introduction to the applications of various spectroscopic techniques such as hyperspectroscopy and vibrational spectroscopies (Raman spectroscopy, FT-NIR, and IR spectroscopy) for the quality and safety assessment of pharmaceutical solid dosage forms. In addition, various chemometric techniques that are highly essential for analyzing the spectroscopic data of pharmaceutical samples are also reviewed.

• IE interfaces
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• v.24 no.2
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• pp.128-138
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• 2011

This research proposes a resource allocation model of Data QC (Quality Control) activities using COQ (Cost of Quality). The model has been developed based on a series of research efforts such as COQ classifications, weight determination of Data QC activities, and an aggregation approach between COQ and Data QC activities. In the first stage of this research, COQ was divided into the four typical classifications (prevention costs, appraisal costs, internal failure costs and external failure costs) through the opinions from five professionals in Data QC. In the second stage, the weights of Data QC activities were elicited from the field professionals. An aggregation model between COQ and Data QC activities has been then proposed to help the practitioners make a resource allocation strategy. DEA (Data Envelopment Analysis) was utilized for locating efficient decision points. The proposed resource allocation model has been validated using the case of Korea national defense information system. This research is unique in that it applies the concept of COQ to the data management for the first time and that it demonstrates a possible contribution to a real world case for budget allocation of national defense information.

• Proceedings of the Acoustical Society of Korea Conference
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• 1998.08a
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• pp.142-147
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• 1998

Recently, 8 kb/s CS-ACELP coder of G.729 is atandardized by ITU-T SG15 and it has been reported that the speech quality of G729 is better than or equal to that of 32kb/s ADPCM. However G.729 is the fixed rate speech coder, and it does not consider the property of voice activity in mutual conversation. If we use the voice activity, we can reduce the average bit rate in half without any degradations of the speech quality. In this paper, we propose an efficient variable rate algorithm for G.729. The variable rate algorithm consists of two main subjects, the rate determination algorithm and algorithm, we combine the energy-thresholding method, the phonetic segmentation method by integration of various feature parameters obtained through the analysis procedure, and the variable hangover period method. Through the analysis of noise features, the 1 kb/s sub rate coder is designed for coding the background noise signal. So, we design the 4 kb/s sub rate coder for the unvoiced parts. The performance of the variable rate algorithm is evaluated by the comparison of speed quality and average bit rate with G.729. Subjective quality test is also done by MOS test. Conclusively, it is verified that the proposed variable rate CS-ACELP coder produced the same speech quality as G.729, at the average bit rate of 4.4 kb/s.

• Proceedings of the Korean Geotechical Society Conference
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• 2001.03a
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• pp.81-88
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• 2001

Electrical resistivity is one of physical property of the earth and measured by electrical resistivity survey, electrical resistivity logging and laboratory test. Recently, electrical resistivity is widely used in determination of rock quality in road and railway tunnel design. To get more reliable rock quality data from electrical resistivity, it needs a lot of test and study on correlation of resistivity and rock quality. Firstly, we did rock property test in laboratory, such as uniaxial compressive strength(UCS), p wave velocity, Young's modulus and electrical resistivity. We correlate each test results and we found out that electrical resistivity has exponentially related to UCS and P wave velocity and linearly related to Young's modulus. And we accomplished electrical resistivity survey in field site and carried out electrical resistivity logging at in-situ area. Also we peformed rock classification, such as RQD, RMR and Q-system and we correlate electrical resistivity to rock classification results. We found out that electrical resistivity logging data are highly correlate to RQD, Q and RMR. Also we found out that electrical resistivity survey data are lower than electrical resistivity logging data when there are faults or fractures. And it cause electrical resistivity survey data to lowly correlate to RQD, Q and RMR.

• Journal of Environmental Impact Assessment
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• v.7 no.2
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• pp.135-143
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• 1998

In order to study the general characteristics of reservoir and stream sediments, various analysis tests were conducted. Water contents and ignition loss were measured to know the primary sediment characteristics. The COD, total phosphorus and nitrogen were contained for the determination of organic substance content. For the purpose of establishing the contamination degree of heavy metals, some heavy metal contents were investigated. In heavy metal contents, reservoir sediments showed somewhat higer value than stream sediments. As a result, the reservoir sediment content of all analysis items were higher than stream sediment.