• Title/Summary/Keyword: Qu

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Quadratic inference functions in marginal models for longitudinal data with time-varying stochastic covariates

  • Cho, Gyo-Young;Dashnyam, Oyunchimeg
    • Journal of the Korean Data and Information Science Society
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    • v.24 no.3
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    • pp.651-658
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    • 2013
  • For the marginal model and generalized estimating equations (GEE) method there is important full covariates conditional mean (FCCM) assumption which is pointed out by Pepe and Anderson (1994). With longitudinal data with time-varying stochastic covariates, this assumption may not necessarily hold. If this assumption is violated, the biased estimates of regression coefficients may result. But if a diagonal working correlation matrix is used, irrespective of whether the assumption is violated, the resulting estimates are (nearly) unbiased (Pan et al., 2000).The quadratic inference functions (QIF) method proposed by Qu et al. (2000) is the method based on generalized method of moment (GMM) using GEE. The QIF yields a substantial improvement in efficiency for the estimator of ${\beta}$ when the working correlation is misspecified, and equal efficiency to the GEE when the working correlation is correct (Qu et al., 2000).In this paper, we interest in whether the QIF can improve the results of the GEE method in the case of FCCM is violated. We show that the QIF with exchangeable and AR(1) working correlation matrix cannot be consistent and asymptotically normal in this case. Also it may not be efficient than GEE with independence working correlation. Our simulation studies verify the result.

Machine Reading Comprehension-based Question and Answering System for Search and Analysis of Safety Standards (안전기준의 검색과 분석을 위한 기계독해 기반 질의응답 시스템)

  • Kim, Minho;Cho, Sanghyun;Park, Dugkeun;Kwon, Hyuk-Chul
    • Journal of Korea Multimedia Society
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    • v.23 no.2
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    • pp.351-360
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    • 2020
  • If various unreasonable safety standards are preemptively and effectively readjusted, the risk of accidents can be reduced. In this paper, we proposed a machine reading comprehension-based safety standard Q&A system to secure supporting technology for effective search and analysis of safety standards for integrated and systematic management of safety standards. The proposed model finds documents related to safety standard questions in the various laws and regulations, and then divides these documents into provisions. Only those provisions that are likely to contain the answer to the question are selected, and then the BERT-based machine reading comprehension model is used to find answers to questions related to safety standards. When the proposed safety standard Q&A system is applied to KorQuAD dataset, the performance of EM 40.42% and F1 55.34% are shown.

Notes on Korean Higher Fungi (한국고등균류기(韓國高等菌類記))

  • Lee, Ji-Yul;Cho, Duck-Hyun
    • The Korean Journal of Mycology
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    • v.3 no.2
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    • pp.13-18
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    • 1975
  • 50 specimens of higher fungi were collected on Mt. Sobaek and Andong areas from September 5, 1974 to July 30, 1975. These fungi were identified by Imazeki and Hongo's classification key based on Singer's taxonomic system. Nine species of them were newly recognized to occur in Korea; Hygrophorus pantoleucus Hongo. Marasmius prasiosmus (Fr.) Fr. Conocybe lactea (Lange) Metrod, Pholiota spumosa(Fr.) Sing., Crepidotus sulphurinus Imaz. et Toki, Pantoleucus retipes (Berk. et Curt.) Sing., Calodon zonatus(Fr.) $Qu{\acute{e}}l$, Patella scutellata (St. Amans) Morgan and Peziza badia Pers. ex Merat.

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Petrological Study on the Jongam granite in the Ogcheon Geosynclinal Zone (옥천지향사대내(沃川地向斜帶內)에 분포(分布)하는 종암화강암(鍾岩花崗岩)의 암석학적(岩石學的) 연구(硏究))

  • Cho, Seon Hyeong
    • Economic and Environmental Geology
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    • v.10 no.4
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    • pp.185-198
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    • 1977
  • This paper is the result of a petrochemical study on the Jongam granite mass which intruded metasediments of Ogcheon zone, locating about 10km northwest from Miweon town, and the mass is $2.5km^2$ in area. In this study, the granite was petrographically analysed in such ways, modal analysis, myrmekite analysis, petrochemical study analysis and tectonic analysis of joint system. The findings are as follows: 1) The area of the granite distributed is a basin surrounded by metasediments. The granite is magma origin. 2) The major mineral composition of the granite are quartz, plagioclase, microcline orthoclase and biotite, and accessaries are muscovite, sericite, magnetite, zircon and sphene. 3) In triangles of $Qu-K{\cdot}fp-PI$, Bi-Or-Hb+Mt and Qu-Ab-Or, the data point areas are similar to those of the NW zone of D.S. Lee (1971) 4) The granite mass can be divided into three granites; quartz monzonite, granodiorite and biotite granite, by petrological aspect in detail. 5) It shows inverse ratio of content between quartz and plagioclase. 6) The myrmekite-texture of the granite are stem type and dominating in northern part. 7) In the tectonic analysis of joint, the strikes are almost constant in direction, N-S direction of dominant joints 8) The geological age of the granites estimated to be Jurassic in age. 9) According to the mineralogical distribution and joint systen, the intrusion direction of the granite magma was infered as from north to south.

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Study on the Synthesis of Isoquercitrin by Enzymatic Partial Hydrolysis (효소를 이용한 부분 가수분해에 의한 isoquercitrin의 합성에 관한 연구)

  • Lee, Seul Bi;Chung, Dae-Won
    • Applied Chemistry for Engineering
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    • v.25 no.2
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    • pp.152-156
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    • 2014
  • Isoquercitrin (IQ), quercetin monoglycoside, is classified as a polyphenol, and a minute quantity of IQ is known to be present in several plants. Recently, it was reported that IQ can be prepared by the partial enzymatic hydrolysis of quercetin diglycoside (rutin, RU). In this paper, the effects of enzyme types, enzyme amounts, and substrate concentrations on the reactivity were investigated using a series of $Pecinex^{TM}$ multi-enzymes. The reaction, when a 8 ml of Ultra Clear to 1 g of RU was applied with the substrate concentration of 1% at $50^{\circ}C$, was found to be optimum, based on the reaction rate and the selectivity to IQ.

Experimental and numerical study on the collapse failure of long-span transmission tower-line systems subjected to extremely severe earthquakes

  • Tian, Li;Fu, Zhaoyang;Pan, Haiyang;Ma, Ruisheng;Liu, Yuping
    • Earthquakes and Structures
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    • v.16 no.5
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    • pp.513-522
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    • 2019
  • A long-span transmission tower-line system is indispensable for long-distance electricity transmission across a large river or valley; hence, the failure of this system, especially the collapse of the supporting towers, has serious impacts on power grids. To ensure the safety and reliability of transmission systems, this study experimentally and numerically investigates the collapse failure of a 220 kV long-span transmission tower-line system subjected to severe earthquakes. A 1:20 scale model of a transmission tower-line system is constructed in this research, and shaking table tests are carried out. Furthermore, numerical studies are conducted in ABAQUS by using the Tian-Ma-Qu material model, the results of which are compared with the experimental findings. Good agreement is found between the experimental and numerical results, showing that the numerical simulation based on the Tian-Ma-Qu material model is able to predict the weak points and collapse process of the long-span transmission tower-line system. The failure of diagonal members at weak points constitutes the collapse-inducing factor, and the ultimate capacity and weakest segment vary with different seismic wave excitations. This research can further enrich the database for the seismic performance of long-span transmission tower-line systems.

Paragraph Re-Ranking and Paragraph Selection Method for Multi-Paragraph Machine Reading Comprehension (다중 지문 기계독해를 위한 단락 재순위화 및 세부 단락 선별 기법)

  • Cho, Sanghyun;Kim, Minho;Kwon, Hyuk-Chul
    • Annual Conference on Human and Language Technology
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    • 2020.10a
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    • pp.184-187
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    • 2020
  • 다중 지문 기계독해는 질문과 여러 개의 지문을 입력받고 입력된 지문들에서 추출된 정답 중에 하나의 정답을 출력하는 문제이다. 다중 지문 기계독해에서는 정답이 있을 단락을 선택하는 순위화 방법에 따라서 성능이 크게 달라질 수 있다. 본 논문에서는 단락 안에 정답이 있을 확률을 예측하는 단락 재순위화 모델과 선택된 단락에서 서술형 정답을 위한 세부적인 정답의 경계를 예측하는 세부 단락 선별 기법을 제안한다. 단락 순위화 모델 학습의 경우 모델 학습을 위해 각 단락의 출력에 softmax와 cross-entroy를 이용한 손실 값과 sigmoid와 평균 제곱 오차의 손실 값을 함께 학습하고 키워드 매칭을 함께 적용했을 때 KorQuAD 2.0의 개발셋에서 상위 1개 단락, 3개 단락, 5개 단락에서 각각 82.3%, 94.5%, 97.0%의 재현율을 보였다. 세부 단락 선별 모델의 경우 입력된 두 단락을 비교하는 duoBERT를 이용했을 때 KorQuAD 2.0의 개발셋에서 F1 83.0%의 성능을 보였다.

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Development and Validation of an Analytical Method for Fenpropimorph in Agricultural Products Using QuEChERS and LC-MS/MS (QuEChERS법과 LC-MS/MS를 이용한 농산물 중 Fenpropimorph 시험법 개발 및 검증)

  • Lee, Han Sol;Do, Jung-Ah;Park, Ji-Su;Cho, Sung Min;Shin, Hye-Sun;Jang, Dong Eun;Choi, Young-Nae;Jung, Yong-hyun;Lee, Kangbong
    • Journal of Food Hygiene and Safety
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    • v.34 no.2
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    • pp.115-123
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    • 2019
  • An analytical method was developed for the determination of fenpropimorph, a morpholine fungicide, in hulled rice, potato, soybean, mandarin and green pepper using QuEChERS (Quick, Easy, Cheap, Effective, Rugged and Safe) sample preparation and LC-MS/MS (liquid chromatography-tandem mass spectrometry). The QuEChERS extraction was performed with acetonitrile followed by addition of anhydrous magnesium sulfate and sodium chloride. After centrifugation, d-SPE (dispersive solid phase extraction) cleanup was conducted using anhydrous magnesium sulfate, primary secondary amine sorbents and graphitized carbon black. The matrix-matched calibration curves were constructed using seven concentration levels, from 0.0025 to 0.25 mg/kg, and their correlation coefficient ($R^2$) of five agricultural products were higher than 0.9899. The limits of detection (LOD) and quantification (LOQ) were 0.001 and 0.0025 mg/kg, respectively, and the limits of quantification for the analytical method were 0.01 mg/kg. Average recoveries spiked at three levels (LOQ, $LOQ{\times}10$, $LOQ{\times}50$, n=5) and were in the range of 90.9~110.5% with associated relative standard deviation values less than 5.7%. As a result of the inter-laboratory validation, the average recoveries between the two laboratories were 88.6~101.4% and the coefficient of variation was also below 15%. All optimized results were satisfied the criteria ranges requested in the Codex guidelines and Food Safety Evaluation Department guidelines. This study could serve as a reference for safety management relative to fenpropimorph residues in imported and domestic agricultural products.

Monitoring and Risk Assessment of Pesticide Residues in Herbal Medicines in Incheon (인천광역시 유통 한약재의 잔류농약 실태 조사 및 위해평가)

  • Min-jeong Kang;Sung-Hee Kwon;Sun-Hoi Kim;Mi-Sook Yeom;Byung-Kyu Park;Hee-jeong Lee;Ji-Hyeung Kim;Kwang-sig Joo;Myung-je Heo;Mun-ju Kwon
    • Journal of Food Hygiene and Safety
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    • v.39 no.2
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    • pp.118-127
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    • 2024
  • This study investigated the levels of 345 pesticide residues in 50 herbal medicines sold in Incheon metropolitan city to determine their safety. Pesticide residues are harmful substances that can cause serious health problems owing to their toxicity and carcinogenicity. The analysis of pesticide residues in the samples was conducted using the quick, easy, cheap, effective, rugged, and safe (QuEChERS) method, known for its high analysis efficiency, to analyze a wide range of pesticides for which no standards have been set. The analysis was cross-validated with the pretreatment method outlined in the Korea Pharmacopoeia. Among the 50 samples encompassing 24 different herbs, 22 pesticide residues were detected in 24 samples, covering 7 distinct herbs, resulting in a detection rate of 48%. It is noteworthy that, except for two cases, all detected pesticides were those for which no standards were set. However, after conducting a risk evaluation considering the daily dosage of herb, it was determined that the levels of pesticide residues were within safe limits. Pesticides with high frequency within the same category of herbs were detected, indicating the necessity for continuous monitoring and regulation. In addition, comparative analysis using the pretreatment method outlined in the Korean Pharmacopoeia, yielded similar results, suggesting the possibility of analyzing pesticide residues in herbs using the QuEChERS method. The study emphasizes the importance of continuous monitoring of pesticide residues in herbs and the development of high-efficiency reliability analysis methods should continue to ensure consumer safety.

Estimation of Diagnostic Range for Measurement Tools, while BMD Testing to Health Examination in Transitional Ages (생애전환기 건강진단 골밀도 검사시 측정도구에 따른 진단범위의 유효성 평가)

  • Kim, Nam-Soo;Jung, Kyung-Sick;Kang, Eun-Jung;Oh, Jung-Eun;Lee, Byung-Kook
    • The Journal of the Korea Contents Association
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    • v.12 no.10
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    • pp.385-394
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    • 2012
  • The aim of this study was to determine the effectiveness of diagnostic range for BMD measurement tools(DEXA, QUS, and RA) to health examination in transitional ages. In standard T-score -2.5 of DEXA, cutoff value by RA is -1.675(sensitivity: 70.0%, specificity: 63.7%) and cutoff value by QUS is -1.733(sensitivity: 70.4, specificity: 59.5%), also T-score -3.0 of DEXA, cutoff value by RA is -2.325(sensitivity: 70.0%, specificity: 42.9%) and cutoff value by QUS is -2.323(sensitivity: 70.4, specificity: 56.8%). There was, however, no significant difference in standard DEXA(lumbar spine and femur) between RA and QUS by repeat measurement(precision), and correlation were without effect. ROC analysis showed that all methods are qualified for BMD measurement tools to health examination in transitional ages; however, the different sensitivities and specificities of the methods, as well as age and gender, calibration parameters for diagnostic tests have to be considered.