• Title/Summary/Keyword: QA Process

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An Empirical Study of the Analytical Measurement Range in Clinical Chemistry (분석측정범위의 실증적 평가)

  • Chang, Sang-Wu;Lee, Sang-Gon;Kim, Young-Hwan;Song, Eun-Young;Park, Yong-Won;Park, Byong-Ok;Lyu, Jae-Gi
    • Korean Journal of Clinical Laboratory Science
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    • v.38 no.2
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    • pp.117-124
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    • 2006
  • The analytical measurement range (AMR) is the range of analyte values that a method can directly measure on a specimen without any dilution, concentration, or other pretreatment not part of the usual assay process. The linearity of the AMR is its ability to obtain test results which are directly proportional to the concentration of analyte in the sample from the upper and lower limit of the AMR. The AMR validation is the process of confirming that the assay system will correctly recover the concentration or activity of the analyte over the AMR. The test specimen must have analyte values which, at a minimum, are near the low, midpoint, and high values of the AMR. The AMR must be revalidated at least every six months, at changes in major system components, and when a complete change in reagents for a procesure is introduced; unless the laboratory can demonstrate that changing the reagent lot number does not affect the range used to report patient test results. The AMR linearity was total protein (0-16.6), albumin (0-8.1), total bilirubin (0-18.1), alkaline phosphatase (0-1244.3), aspartate aminotransferase (0-1527.9), alanine aminotransferase (0-1107.9), gamma glutamyl transpeptidase (0-1527.7), creatine kinase (0-1666.6), lactate dehydrogenase (0-1342), high density lipoprotein cholesterol (0.3-154.3), sodium (35.4-309), creatinine (0-19.2), blood urea nitrogen (0.5-206.2), uric acid (0-23.9), total cholesterol (-0.3-510), triglycerides (0.7-539.6), glucose (0-672.7), amylase (0-1595.3), calcium (0-23.9), inorganic phosphorus (0.03-17.0), potassium (0.1-116.5), chloride (3.3-278.7). We are sure that materials for the AMR affect the evaluation of the upper limit of the AMR in the process system.

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A study on the Improvement of Facility-Wide Quality Assurance Technique for Quality Management of Military Product (군수품 품질경영 효율화를 위한 사업장 단위 품질 보증 개선 방안 연구)

  • Kang, In-Myun
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.12
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    • pp.613-619
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    • 2017
  • Recently, the development and production of weapons systems for military products have been increasing. Therefore, there is a need for an efficient quality control method suitable for limited resources and manpower for the manufactured military products. Military munitions are characteristically developed and produced as business contract units. In addition, business and quality control are done by contract. For this reason, many contracts are concluded in one producer and similar products are often produced. Business and quality control also require extensive manpower and effort. If a company produces several similar products, a more efficient management approach is required. This study therefore examines these problems in an attempt to present solutions by analyzing the types of munitions contracts and the characteristics of products produced by one company. Based on the results, a method is proposed to manage the contract-specific management methods by company, that is, by business site. The method is applied to an engine manufacturing company and the integrated management plan is verified and its effectiveness confirmed. The effect of facility-wide method was a reduction of QA manpower and an improvement in maintaining quality assurance and stability through management of the workforce and contract grouping method.

Uncertainty Assessment: Relative versus Absolute Point Dose Measurement for Patient Specific Quality Assurance in EBRT

  • Mahmood, Talat;Ibrahim, Mounir;Aqeel, Muhammad
    • Progress in Medical Physics
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    • v.28 no.3
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    • pp.111-121
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    • 2017
  • Verification of dose distribution is an essential part of ensuring the treatment planning system's (TPS) calculated dose will achieve the desired outcome in radiation therapy. Each measurement have uncertainty associated with it. It is desirable to reduce the measurement uncertainty. A best approach is to reduce the uncertainty associated with each step of the process to keep the total uncertainty under acceptable limits. Point dose patient specific quality assurance (QA) is recommended by American Association of Medical Physicists (AAPM) and European Society for Radiotherapy and Oncology (ESTRO) for all the complex radiation therapy treatment techniques. Relative and absolute point dose measurement methods are used to verify the TPS computed dose. Relative and absolute point dose measurement techniques have a number of steps to measure the point dose which includes chamber cross calibration, electrometer reading, chamber calibration coefficient, beam quality correction factor, reference conditions, influences quantities, machine stability, nominal calibration factor (for relative method) and absolute dose calibration of machine. Keeping these parameters in mind, the estimated relative percentage uncertainty associated with the absolute point dose measurement is 2.1% (k=1). On the other hand, the relative percentage uncertainty associated with the relative point dose verification method is estimated to 1.0% (k=1). To compare both point dose measurement methods, 13 head and neck (H&N) IMRT patients were selected. A point dose for each patient was measured with both methods. The average percentage difference between TPS computed dose and measured absolute relative point dose was 1.4% and 1% respectively. The results of this comparative study show that while choosing the relative or absolute point dose measurement technique, both techniques can produce similar results for H&N IMRT treatment plans. There is no statistically significant difference between both point dose verification methods based upon the t-test for comparing two means.

Estimating Concrete Compressive Strength Using Wave Propagation Method (Wave Propagation 기법을 이용한 콘크리트의 압축강도 추정)

  • Kwon, Soo-Ahn;An, Ji-Hwan;Suh, Young-Chan;Cho, Yong-Joo
    • International Journal of Highway Engineering
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    • v.7 no.3 s.25
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    • pp.63-69
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    • 2005
  • For many years, the compressive strength of concrete has been regarded as an important index in determining concrete pavement quality. The compressive strength of the sample cores from the field has been used as quality index of concrete pavement. However, this process is time consuming and requires a lot of labor. Recently, the M-E Design Methodology in the pavement design based on the elastic modulus has been adopted. Therefore, several NDT methodologies have been adopted for QA/QC in the field and for the pavement design. Among various NDT methods, the wave propagation method can be used to measure the elastic modulus of concrete because the wave velocity is directly related to the elastic modulus. Therefore, in this study the wave propagation method was used for estimating the concrete modulus. The relationship between the compressive strength measured in he laboratory and the elastic modulus measured by the wave propagation method was analyzed, and the compressive strength was estimated from the elastic modulus for various mix types. The results showed that the relationship between the elastic modulus and the compressive strength was observed and the relationship varied depending on the aggregate types.

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The Impacts of Piezoelectric Elements' Defects On Color & Power Doppler Images (초음파 프로브에서 소자결함이 컬러 및 파워 도플러 영상에 미치는 영향)

  • Lee, Kyung-Sung
    • Journal of radiological science and technology
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    • v.38 no.4
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    • pp.443-449
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    • 2015
  • An ultrasound probe has a big impact on Doppler images even though it has very high risk of frequent function-breakdowns occurring in medical ultrasound scanners. This study experimentally analyses the impacts of an ultrasonic probe's defected elements on power & color Doppler images. The results show that, the bigger the size of defected probe elements is, and the closer a group of action elements is to the center, the more the brightness of images and the velocity of Doppler diminish. When elements' defects increase in color & power Doppler images, false images are formed to be mistaken for blood-vessel plaque in neighboring regions. Accordingly, whenever element defects are suspected, we need check-up process in B-mode. From this respective, it is advisable to have primary interest in a probe and carry out continuous probe QA for ultrasonography.

Verification of set-up accuracy using MLC leakage (MLC leakage를 이용할 Verification의 효용성 고찰)

  • Yun InHa;Hong DongGi;Jung WangKwon;Seo DongRin;Yun HwaRyeong;Kim JungMan
    • The Journal of Korean Society for Radiation Therapy
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    • v.16 no.1
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    • pp.11-19
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    • 2004
  • Purpose : Verification within 5mm is one of the important QA process of IMRP and SRS. Therefore, we improve accuracy of patients set-up using scale point. Materials and Methods : We compare MLC scale pointer with customerized port film graticule for patients who was underwent IMRT and SRS. Results : Scale pointer using MLC showed accurate location of patients landmark including divergency of beam, and any point of patient could be certified by means of cross of MLC. Conclusion : MLC scale pointer is effective and convenient method in verification of patients set-up using L-gram.

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A Study on the Game Quality Management Methodology (게임품질관리 수업 개선을 위한 게임 플레이 분석 시스템 설계)

  • Lee, Yoon-Yim;Rhee, Dae-Woong
    • Journal of Korea Game Society
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    • v.19 no.1
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    • pp.85-94
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    • 2019
  • This paper aims to improve teaching methods for changing the game-related department and game quality management classes of A university from theoretical to practical classes. The main goal is to design and develop a game play analysis system. The design and development of the game play analysis system enables the company to experience the overall process of game development that meets the requirements of the industry. Designs for systems that can improve understanding of game content by experiencing debugging to testing.

Expert Review and Analysis of the Game's Testing Process -Focus on balance testing- (게임의 테스트 프로세스에 따른 전문가 검토 및 분석 -밸런스 테스트를 중심으로-)

  • Lee, Yoon-Yim;Rhee, Dea-Woong
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.26 no.7
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    • pp.1013-1018
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    • 2022
  • Game Industry sustained growth for some time, but the lifespan of a game is shortening. Various efforts to improve the quality of services for the game players which play a role in extending the lifespan of games. When a game is serviced, the server of the game starts to store log informations, and the stored data became important measures to predict game user's activities. As the game's data gathers, it becomes highly useful big data. By analyzing the data of the game stored in this way, a game service issue analysis procedure is proposed to improve the quality of the game service and to proceed with a better service, and based on the analysis in this way, it was applied to the balance test process and verified through expert to the balance test process. If the log analysis process is applied through this paper, it will be a basic data that can improve the quality of game services.

Cost-effective Investigation on Contaminated Land and Assessment of Measurement Uncertainty (오염토양의 효율적 조사기법과 측정불확도의 평가방법)

  • 이종천
    • Economic and Environmental Geology
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    • v.37 no.1
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    • pp.49-59
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    • 2004
  • The concectration and distribution of contaminants obtained from a contaminated land investigation or an environmental geochemistry survey constitutes the basis of a decision-making process on environmental policies or of scientific researches. As the quality of data determines the reliability of the result, the investigation plan should be adjusted according to the purpose of the investigation. In general, the effort to improve the data quality had been focused mainly on the QA/QC procedures in laboratories. The rapid progress of analytical instrument has also contributed toward improving the analytical precision to a sacrificable degree. Nevertheless, in many cases, it is not the analytical precision that needs improvement for the better precision of overall measurement process: it is rather during the sampling process in the field that is responsible for the poor precision. To assess the data quality on a measured value, ISO recommends to provide information on "measurement uncertainty" along with the measured value. The measurement uncertainty in an environmental measurement context can be explained as the statistical number that expresses the degree of the uncertainty stemming from the sampling and analytical procedures. There is a cost involved in order to improve the precision of sampling and analytical methods so as to decrease the degree of measurement uncertainty. The economical point of compromise in an investigation planning can be achieved when the allowable degree of uncertainty has been set before-hand. The investigation can then be planned accordingly not to exceed the uncertainty limit. Furthermore, if the measurement uncertainty estimated from the preliminary investigation can be separated into sampling and analytical uncertainties, it can be used as a criterion where the resources for the investigation should be allotted cost-effectively to reinforce the weakest link of the whole investigation process. This paper aims to present a method of estimating the level of measurement uncertainty of a measured contamination concentration at a site used as an example and to show how the estimated uncertainty can be applied to serve the particular purpose of an investigation.

A Study on Model for Evaluating ERP Project from Customer and Consulting Firm Perspectives using AHP (AHP를 활용한 고객사와 컨설팅사의 ERP 프로젝트 평가모형 연구)

  • Jeong, Hee-Yeon;Lee, Jonh Hearn
    • Information Systems Review
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    • v.8 no.1
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    • pp.241-263
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    • 2006
  • Since 1995 many enterprises have introduced ERP to strengthen competitive power. However, enterprises that have introduced ERP for the first time have experienced various types of problems integrating them; to this day, there are only a few enterprises that have implemented ERP successfully. The main reason for the failures of successful ERP implementing is that enterprises frequently ignore and/or don't know how to systematically evaluate the construction process of ERP and busy finishing a phase without resolving problems before going on to the next phase. This research focused on the implementation process of ERP project to evaluate the process of ERP at each phase. As a result, we propose an evaluation model of ERP project as a tool to find critical problems at each phase and improve on how to resolve the problems found at each phase. This evaluation model makes it possible to introduce ERP successfully by presenting the basis of assessment which will be used by enterprises to minimize the trial and error of construction process of ERP.