• Journal of The Korean Society of Integrative Medicine
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• 제7권4호
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• pp.23-32
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• 2019

Purpose : The purpose of this study was to evaluate the effects of multi-sensory treatment programs on attention and learning in ADHD children. Methods : The program was provided for 50 minutes twice a week for a total of 12 times over 6 weeks. The FAIR concentration test was used to identify the children's concentration of attention before and after the intervention. The children's learning ability was evaluated using K-ABC. Results : When attention was evaluated using FAIR, there was a significant increase in all dependencies of performance value (P), quality value (Q), and continuity value (C) (p>.05). In addition, when learning ability was evaluated using K-ABC, learning ability in general increased significantly (p>.05). The multi-sensory play therapy program had a positive effect on the children's attention and learning ability and thus it is a positive intervention method for children with ADHD. Conclusion : In addition to providing challenging activities, the program showed that it was possible to elicit the children's interest by engaging a variety of senses at the same time. This is believed to have motivated them internally to engage actively in the program.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• 제45권5호
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• pp.393-400
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• 2017

A virtual simulation test program to carry out the handling qualities of unmanned Rotorcraft has developed by using the MATLAB GUIDE(Graphic User Interface Development Environment). The handling quality evaluation program based on ADS-33E contributes to design the flight control system and to evaluate handling qualities. In addition, Linear Quadratic Tracker with Integrator(LQTI) attitude controller based on Linear Quadratic Regulator(LQR) for to rotorcraft BO-105C and the effects of the handling qualities is analyzed change to weight matrices of the Q and R.

• Journal of the Korean Geosynthetics Society
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• 제18권3호
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• pp.1-9
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• 2019

In this study, the effect of ground improvement was to be verified by granular compaction pile from the ground reclaimed with Fly Ash landfill site. The depth and strength parameters of the Fly ash layer was determined using the ground investigation and cone penetration test. And the STONE C program was used to predict the strength parameter, bearing capacity and settlement of the improved ground. As a result of the plate bearing test, the bearing capacity of improvement ground was higher than the design load and the settlement was smaller than the reference value. After the construction, the improvement effect by the cone penetration test was confirmed. The cone penetration resistance value($q_c$) increased by 250% to 500% and the effect was excellent.

• Fisheries and Aquatic Sciences
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• 제19권2호
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• pp.11.1-11.7
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• 2016

In this study, purified peptides from shrimp waste hydrolysates (SWHs) were examined for their inhibitory effects against ${\beta}$-secretase. During consecutive purification using a Sephadex G-25 column chromatography and high performance liquid chromatography on a C18 column, a potent ${\beta}$-secretase inhibitory peptide Asp-Val-Leu-Phe-His (629 Da) was isolated and identified from SWH24 by Q-TOF MS/MS and the $IC_{50}$ value was determined to be $92.70{\mu}M$. The ${\beta}$-secretase inhibition patterns of the purified peptides were found to be competitive. Among synthesized ${\beta}$-secretase inhibitory peptides, Leu-Phe-His had higher ${\beta}$-secretase inhibitory activity than the others. The result of this study suggests that the ${\beta}$-secretase inhibitory peptide derived from SWH24 could be potential candidates to develop nutraceuticals and pharmaceuticals.

• Journal of Korean Society for Quality Management
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• 제47권3호
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• pp.479-496
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• 2019

Purpose: The purpose of this research is to develop defense quality evaluation model in order to improve the problem of private sector quality evaluation model and propose the total integrated defense quality management model which enables to evaluate not only large defense industry, but also small-medium industry. Methods: This paper consider the characteristics on ISO 9001 Quality Management System, single PPM, PASS and defense quality and develop defense quality maturity model and index which enables to measure the current quality management level and characteristics and to evaluate operational characteristics in each maturity level for domestic defense industry. Results: From 176 DQMS certified defense industry, the defense quality maturity level is 68,2, C grade. The large defense industry shows, 80.9, A grade; medium industry 69.7, C grade; small-medium industry shows 54.1, D grade. Through the classified types of industries, the current level of quality management of defense industries was diagnosed and the areas to be supplemented for the total quality management were identified. Conclusion: Developed DQMI can be used as the basic information for spreading quality management activities in the defense industry by diagnosing the overall quality management of existing defense industries and quantifying the ambiguity of non-metric measurements and measurement standard that were presented as the threshold of the defense quality management system certification process.

• Quality Improvement in Health Care
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• 제5권2호
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• pp.190-201
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• 1998

Background : Medical equipments take a very important role in diagnosis and treatment of disease in modern medicine and effective maintenance of the equipments is a necessary to provide a good health care to the public. After developing a new QC program for effective maintenance of medical equipments and practicing it for a year, we report the results of the new program. Methods : The maintenance data of 9 equipments in 8 categories including a CT Scanner were analyzed with regard to the parts responsible for most frequent failure and cause of the failure. After learning the most frequent failure part and cause of the failure, we developed a new QC program that emphasizes preventive maintenance of the most frequent failure part. We compared the number of failure per year and active rate of each equipment before and after the adoption of the new QC program. Results : The average number of failure per year per equipment was 20.7 before and it decreased by 43% to 11.9 after adoption of the new QC program. The average active rate of the equipments was 92.6% before and it increased by 3.2% to 95.8% after adoption of the new program. Conclusions : The practice of the new QC program appears very useful as it decreased the failure rate and increased the active rate of the equipments.

• Journal of Life Science
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• 제13권3호
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• pp.291-297
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• 2003

A human endogenous retroviral family (HERV-W) has recently been described that is related to multiple sclerosis-associated retrovirus (MSRV) sequences that have been identified in particles recovered from monocyte cultures from patients with multiple sclerosis. Two pol fragments (HWP-FB10 and HWP-FBl2) of HERV-W family were identified and analysed by the PCR approach with cDNA library of human fetal brain. They showed 89 percent nucleotide sequence similarity with that of the HERV-W (accession no. AF009668). Deletion/insertion or point mutation in the coding region of the pol fragments from human fetal brain resulted in amino acid frameshift that induced a mutated protein. Phylogenetic analysis of the HERV-W family from GenBank database indicates that the HWP-FB10 is very closely related to the AC000064 derived from human chromosome 7q21-q22. Further studies on the genetic relationship with neighbouring genes and functional role of these new HERV-W pol sequences are indicated.

• Proceedings of the Korean Geotechical Society Conference
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• 한국지반공학회 2008년도 춘계 학술발표회 초청강연 및 논문집
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• pp.636-643
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• 2008

The objective of this paper is to assess the potential use of the geogauge and the light falling weight deflectometer (LFWD) and the soil impact hammer as quality control/quality assurance $Q_C/Q_A$ devices for compacted soil layers. A comprehensive field experimental program considering variation of number of compaction, water contents and thickness of compaction layer was conducted on compacted layers of gravel sand. The geogauge, LFWD, the soil impact hammer and static load test (PLT) as a reference test were performed for the compacted layers. The geogauge elastic modulus, $E_G$, the LFWD dynamic modulus, ELFWD, empirical soil stiffness, $K_{30}$, obtained from soil impact hammer and soil stiffness directly obtained from PLT, $K_{30}$, were correlated with increasing number of compaction. The results of this study show that the geogauge, LFWD and the soil impact hammer, which are very simple to test, can be used as substituting devices for static PLT which is a conventional quality control/quality assurance $Q_C/Q_A$ devices for compacted soil layers.

• Journal of Microbiology and Biotechnology
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• 제12권6호
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• pp.972-978
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• 2002

Streptomyces sp. AD001 is a Gram-positive soil actinomycetes secreting an uncharacterized 2,4-dichlorophenol (DCP) oxidizing enzyme, whose activity is similar to the previously known Actinomycetes lignin-peroxidase (ALiP). This extracellular peroxidase was purified from Streptomyces sp. AD001 as a single protein band on an SDS-PACE by ammonium sulfate fractionation, Q-sepharose, concanavalin A, and Bio-Gel HTP column chromatographies. The molecular mass of the purified peroxidase was determined by SDS-PAGE to be 45.2 kDa, and 49.7 kDa with MALDI-TOF-MS, respectively. The highest level of peroxidase activity was observed at pH 7.5 and $30^{\circ}C$. The amino terminal sequence of the purified peroxidase (G-E-P-E-E-G-N-V-D-G-T-L) showed no significant homologies to my known proteins, suggesting that Streptomyces sp. AD001 may secrete a novel kind of bacterial peroxidase Initial rate kinetic data of the 2,4-DCP oxidation were best modeled with a random-binding bireactant system.

• Journal of Korean Society on Water Environment
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• 제31권6호
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• pp.653-664
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• 2015

TPLMS (Total water pollutant load management system) that is the most powerful water-quality protection program have been implemented since 2004. In the implementation of TPLMS, target water-quality and permissible discharged load from each unit watershed can be decided by water-quality modeling. And NPS (Non-point sources) discharge coefficients associated with certain (standard) flow are used on estimation of input data for model. National Institute of Environmental Research (NIER) recommend NPS discharge coefficients as 0.15 (Q₂₇₅) and 0.50 (Q₁₈₅) in common for whole watershed in Korea. But, uniform coefficient is difficult to reflect various NPS characteristics of individual watershed. Monthly NPS discharge coefficients were predicted and estimated using surface flow and water-quality from HSPF watershed model in this study. Those coefficients were plotted in flow duration curve of study area (Palger stream and Geumho C watershed) with monthly average flow. Linear regression analysis was performed about NPS discharge coefficients of BOD, T-N and T-P associated with flow, and R² of regression were distributed in 0.893~0.930 (Palger stream) and 0.939~0.959 (Geumho C). NPS Discharge coefficient through regression can be estimated flexibly according to flow, and be considered characteristics of watershed with watershed model.