• 제목/요약/키워드: Pyridyl-N

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The Coordination of Pyridyl-N to Pentacyanoferrate for the Electrochemical Detecting Small Organic Molecules

  • Choi, Young-Bong;Jeon, Won-Yong;Kim, Hyug-Han
    • Bulletin of the Korean Chemical Society
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    • 제34권2호
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    • pp.595-599
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    • 2013

  • The coordination of pyridyl-N to pentacyanoferrate for the detection of small organic antigens in solution is presented. The unique contribution of this paper is the direct conjugation of pyridyl-N in small organic antigens to pentacyanoferrate. Pentacyanoferrate is promising as an electrochemical label owing to its good electro-chemical properties, which can be utilized to generate an electrical signal in homogeneous electrochemical immunoassays. The facilely synthesized pyridyl-N to pentacyanoferrate was characterized by the electrochemical and spectroscopic methods. Hippuric acid (HA) has been detected competitively on the interaction of free HA and pentacyanoferrate-(4-aminomethylpyridine-hippuric acid) (Fe-HA) to its antibody, with the detection limit of 0.50 ${\mu}g\;mL^{-1}$. While pentacyanoferrate-based immunoassay is in its simplicity and infancy, the proposed immunoassay offers attractive opportunities for developing pyridyl-N-based the electrochemical detection of small organic antigens in the health care area.

  • https://doi.org/10.5012/bkcs.2013.34.2.595 인용 PDF KSCI

Surface Enhanced Raman Spectroscopic Studies on Zn(Ⅱ) and Mn(Ⅲ) Tetrakis (4-N-Methyl Pyridyl) Porphyrins

  • Song, Ok-Keun;Yoon, Min-Joong;Kim, Dong-Ho
    • Bulletin of the Korean Chemical Society
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    • 제11권4호
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    • pp.286-290
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    • 1990

  • The surface enhanced Raman scatterings of Zn(Ⅱ) tetrakis (4-N-methyl pyridyl) porphyrins were studied in silver sol. Zn(Ⅱ) tetrakis (4-N-methyl pyridyl) porphyrin was found to be adsorbed on silver surface via flat-on geometry with some inhomogeneous distribution in the orientation of pyridyl groups. Both the selective enhancement of Raman modes depending on the mode character and the theoretical arguments of SERS are utilized to support the above conclusion. The surface induced substitution reaction of Mn(Ⅲ) tetrakis (4-N-methyl pyridyl) porphyrin chloride to Ag(Ⅱ) tetrakis (4-N-methyl pyridyl) porphyrin was detected via surface enhanced Raman spectrum.

  • https://doi.org/10.5012/bkcs.1990.11.4.286 인용 PDF

몇 가지 전이금속, Ni(II), Cu(II) 및 Zn(II) 3,6-bis(2'-pyridyl)pyridazine 착 화합물들의 세포 독성효과 (Cytotoxic Effects of Some Transition Metals, Nickel(II), Copper(II) and Zinc(II), with 3.6-bis(2'-pyridyl)pyridazines Complexes)

  • 권병목;이정옥;최상운;성낙도
    • Applied Biological Chemistry
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    • 제49권1호
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    • pp.21-24
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    • 2006

  • 6종의 인체 암(폐암, 피부암, 결장암, 자궁암, 선암 및 뇌암)과 그의 17가지 세포주들에 대한 리간드 화합물 3,6-bis(2'-pyridyl)pyridazine(1) 과 3,6-bi s(6'-methyl-2'-pyridyl)pyridazine(2) 그리고 그들의 전이금속(Ni(II), Cu(II) 및 Zn(II)) 착 화합물들 $(3{\sim}6)$ 세포독성을 각각 측정하였다. 그 결과, 특히 Cu(II) 착 화합물, bis-[3,6-bis-(6'-methyl-2'-pyridyl)pyridazine-$k^2N^2,N^3$]chlorocopper(II)perchlorate (4)는 뇌암(SNB-19)과 결장암(SW-62) 세포주에 대하여 제1세대 항암제인 Cis-platin보다 높은 세포독성을 나타내었다.

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Synthesis, Structures, and Catalytic Properties of Ionic Metallacyclodimeric Palladium(II) Complexes

  • Kim, Sung Min;Park, Kyung Hwan;Lee, Haeri;Moon, So Yun;Jung, Ok-Sang
    • Bulletin of the Korean Chemical Society
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    • 제33권12호
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    • pp.4069-4073
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    • 2012

  • Metallacyclodimeric complexes of $[(Me_4en)Pd(L)]_2(ClO_4)_4$ ($Me_4en$ = N,N,N',N'-tetramethylethylenediamine; L = dimethylbis(4-pyridyl)silane (dmps), methylvinylbis(4-pyridyl)silane (mvps)) have been synthesized, and their structures have been characterized by X-ray single crystallography. The skeletal structures consist of one 20-membered metallamacrocycle, two 5-membered metallacycles, and four pyridyl groups. The local geometry around the palladium(II) ion approximates to a typical square planar arrangement with four nitrogen donors. Delicate difference in catalytic effects on hydrogenation was investigated based on the structure of catalyst and substrates.

  • https://doi.org/10.5012/bkcs.2012.33.12.4069 인용 PDF KSCI

N,N'-Oxalylbis(2-pyridyl-3'-sulphobenzoylhydrazone)을 이용한 철의 형광광도법 정량 (Fluorimetric Determination of Iron with N,N'-Oxalylbis(2-pyridyl-3'-sulphobenzoylhydrazone))

  • 박기민;김용남
    • 대한화학회지
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    • 제37권6호
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    • pp.585-589
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    • 1993

  • N,N'-oxalylbis(2-pyridyl-3'-sulphobenzoyl hydrazone)(OPSH)를 발광시약으로 사용하여 형광광도법으로 Fe(Ⅲ)을 정량하는 방법을 개발하였다. pH 3인 수용액에서 290 nm를 들뜸 파장으로 하여 367 nm에서 Fe(Ⅲ) 착물의 형광세기를 측정하여 정량하였다. Fe(Ⅲ)의 농도가 2000~10ng/ml인 범위에서 정량이 가능하였으며 이 방법을 합성시료 및 수도물의 분석에 적용하였다.

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N,N'-Oxalylbis(2-pyridyl-3'-sulphobenzoylhydrazone)을 이용한 구리의 분광광도법 및 미분 분광광도법 정량 (Spectrophotometric and Derivative Spectrophotometric determination of Copper with N,N'-Oxalylbis(2-Pyridyl-3'-sulphobenzoylhydrazone))

  • 김용남;최규성;최승춘;정유진
    • 대한화학회지
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    • 제37권1호
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    • pp.112-118
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    • 1993

  • 수용성 발색시약인 N,N'-oxalylbis(2-pyridyl-3'-sulphobenzoylhydrazone)을 합성하여 분광광도법 및 1, 2차 미분 분광광도법에 의한 구리의 정량법을 개발하였다. 정량은 구리착물 수용액(pH 1.89)의 흡광도 및 1,2차 미분값을 379, 395, 363 그리고 421nm의 파장에서 각각 측정함으로써 수행되었다. 정량 가능한 구리의 농도 범위는 0.12~1.20${\mu}g$ /ml 였으며 이 방법을 알루미늄 합금시료의 분석에 적용하였다. 2차 미분 분광광도법으로 421nm에서 측정했을 때가 가장 좋은 결과를 나타내었다.

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[3,6-bis(6'-methyl-2'pyridyl)pyridazine]$ZnCl_2 (C_{16}H_{16}N_4\cdotZnCl_2)$의 결정 구조 (The Crystal Structure of [3,6-bis(6'-methyl-2'pyridyl)pyridazine]$ZnCl_2,(C_{16}H_{16}N_4\cdotZnCl_2)$)

  • 김문집;이재혁;이한준;성낙도
    • 한국결정학회지
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    • 제10권2호
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    • pp.119-124
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    • 1999

  • X-선 회절법을 이용하여 3,6-bis(6'-methyl-2'pyridyl)pyridazine을 리간드로 한 Zn(Ⅱ) 착물인 [3,6-bis(6'-methyl-2'pyridyl)pyridazine]ZnCl2 (C16H16N4·ZnCl2)의 결정구조를 규명하였다. 이 결정의 결정계는 Monoclinic이며 공간군은 P21/a이다. 단위포 상수는 a=15.053(7) Å, b=14.594(7) Å, c=7.628(3) Å이며, β=93.92(4)°, V=1671.9(13) Å3, T=293(2)K, Z=4, Dc=1.594 Mgm-3이다. 회절반점들의 세기는 Enraf-Nonius CAD-4 diffractometer로 얻었으며 Mo Kα선(λ=0.71073 Å)을 사용하였다. 분자구조는 직접법으로 풀었으며, Fo>4σ (Fo)인 1750개의 독립 회절 데이터에 대하여 최소승자법으로 정밀화하여 최종 신뢰도 값 R=8.31%을 얻었다.

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