• Bulletin of the Korean Chemical Society
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• v.34 no.2
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• pp.595-599
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• 2013

The coordination of pyridyl-N to pentacyanoferrate for the detection of small organic antigens in solution is presented. The unique contribution of this paper is the direct conjugation of pyridyl-N in small organic antigens to pentacyanoferrate. Pentacyanoferrate is promising as an electrochemical label owing to its good electro-chemical properties, which can be utilized to generate an electrical signal in homogeneous electrochemical immunoassays. The facilely synthesized pyridyl-N to pentacyanoferrate was characterized by the electrochemical and spectroscopic methods. Hippuric acid (HA) has been detected competitively on the interaction of free HA and pentacyanoferrate-(4-aminomethylpyridine-hippuric acid) (Fe-HA) to its antibody, with the detection limit of 0.50 ${\mu}g\;mL^{-1}$. While pentacyanoferrate-based immunoassay is in its simplicity and infancy, the proposed immunoassay offers attractive opportunities for developing pyridyl-N-based the electrochemical detection of small organic antigens in the health care area.

• Bulletin of the Korean Chemical Society
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• v.11 no.4
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• pp.286-290
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• 1990

The surface enhanced Raman scatterings of Zn(Ⅱ) tetrakis (4-N-methyl pyridyl) porphyrins were studied in silver sol. Zn(Ⅱ) tetrakis (4-N-methyl pyridyl) porphyrin was found to be adsorbed on silver surface via flat-on geometry with some inhomogeneous distribution in the orientation of pyridyl groups. Both the selective enhancement of Raman modes depending on the mode character and the theoretical arguments of SERS are utilized to support the above conclusion. The surface induced substitution reaction of Mn(Ⅲ) tetrakis (4-N-methyl pyridyl) porphyrin chloride to Ag(Ⅱ) tetrakis (4-N-methyl pyridyl) porphyrin was detected via surface enhanced Raman spectrum.

• Applied Biological Chemistry
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• v.49 no.1
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• pp.21-24
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• 2006

A series of cytotoxic activities $(ED_{50})$ in vitro against six human cancers (lung cancer, uterine cancer, skin cancer, brain cancer, colon cancer and adenocarcinoma) and their seventeen cell lines of 3,6-bis(2'-pyridyl)pyridazine, 1, 3,6-bis-(6'-methyl-2'-pyridyl)pyridazine, 2 and their transition metal, Ni(II), Cu(II) and Zn(II) complexes, $3{\sim}6$ were measured. Particularly, the results revealed that the cytotoxic activities against the brain cancer cell line (SNB-19) and the colon cancer cell line (SW62) of bis- [3,6-bis-(6'-methyl-2'-pyridyl)pyridazine-$k^2N^2,N^3$]chlorocopper(II)perchlorate, 4 were shown to be higher than that of the first generation anticancer agent, Cis-platin.

• Bulletin of the Korean Chemical Society
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• v.33 no.12
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• pp.4069-4073
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• 2012

Metallacyclodimeric complexes of $[(Me_4en)Pd(L)]_2(ClO_4)_4$ ($Me_4en$ = N,N,N',N'-tetramethylethylenediamine; L = dimethylbis(4-pyridyl)silane (dmps), methylvinylbis(4-pyridyl)silane (mvps)) have been synthesized, and their structures have been characterized by X-ray single crystallography. The skeletal structures consist of one 20-membered metallamacrocycle, two 5-membered metallacycles, and four pyridyl groups. The local geometry around the palladium(II) ion approximates to a typical square planar arrangement with four nitrogen donors. Delicate difference in catalytic effects on hydrogenation was investigated based on the structure of catalyst and substrates.

• Bulletin of the Korean Chemical Society
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• v.22 no.4
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• pp.421-423
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• 2001

• Journal of the Korean Chemical Society
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• v.37 no.6
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• pp.585-589
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• 1993

A fluorimetric method for the determination of Fe(Ⅲ) using N,N'-oxalylbis(2-pyridyl-3'-sulphobenzoyl hydrazone)(OPSH) as a emission reagent has been developed. Determination has been performed by measuring the fluorescence intensity of Fe(Ⅲ) complex at 367 nm in aqueous solution (pH 3) with 290 nm excitation. There was a linear relationship between Fe(Ⅲ) concentration and fluorescence intensity over the range 2000∼10 ng/ml. The method has been applied to the determination of Fe(Ⅲ) in synthetic mixtures and tap water

• Journal of the Korean Chemical Society
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• v.42 no.2
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• pp.228-231
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• 1998

• Journal of the Korean Chemical Society
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• v.37 no.1
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• pp.112-118
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• 1993

A water-soluble chromogenic reagent, N,N'-oxalylbis(2-pyridyl-3'-sulphobenzoylhydrazone) has been synthesized. Spectrophotometric and first-and second-derivative spectrophotometric methods for the determination of copper with the reagent have been developed. Determination has been performed by measuring the absorbance and the first-and second-derivative values of the copper complexes in aqueous solutions (pH 1.89) at 379, 395, 363 and 421 nm, respectively. The method allows the determination of 0.12-1.20 ${\mu}g$ /ml of copper and has been applied to the analysis of aluminium alloy samples. The best results have been obtained from the measurements of the second-derivative values at 421 nm.

• Korean Journal of Crystallography
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• v.10 no.2
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• pp.119-124
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• 1999

X-선 회절법을 이용하여 3,6-bis(6'-methyl-2'pyridyl)pyridazine을 리간드로 한 Zn(Ⅱ) 착물인 [3,6-bis(6'-methyl-2'pyridyl)pyridazine]ZnCl2 (C16H16N4·ZnCl2)의 결정구조를 규명하였다. 이 결정의 결정계는 Monoclinic이며 공간군은 P21/a이다. 단위포 상수는 a=15.053(7) Å, b=14.594(7) Å, c=7.628(3) Å이며, β=93.92(4)°, V=1671.9(13) Å3, T=293(2)K, Z=4, Dc=1.594 Mgm-3이다. 회절반점들의 세기는 Enraf-Nonius CAD-4 diffractometer로 얻었으며 Mo Kα선(λ=0.71073 Å)을 사용하였다. 분자구조는 직접법으로 풀었으며, Fo>4σ (Fo)인 1750개의 독립 회절 데이터에 대하여 최소승자법으로 정밀화하여 최종 신뢰도 값 R=8.31%을 얻었다.

• Bulletin of the Korean Chemical Society
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• v.35 no.2
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• pp.647-650
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• 2014