• 한국환경과학회지
• /
• 제12권4호
• /
• pp.477-480
• /
• 2003

Pesticides were extracted from samples with 70% acetone and methylene chloride in order, and then cleaned up via open-column chromatography apparatus packed with florisil, and finally analyzed simultaneously the organochlorine and pyrethroid pesticides using GC(ECD). An ultra-2 fused silica capillary column was used to separate and identify the products. The resolution between the last isomeric peak of cypermethrin(59.987min) and the first isomeric peak of flucythrinate(60.043min) was not satisfactory. The last isomeric peak of fenvalerate(62.344min) and the first isomeric peak of fluvalinate(62.397min) were overlapped. Recoveries of soybean sample fer the most pesticides were 73.3% to 102.4%. Detection limits were between 0.004 and 0.063 ${\mu}$g/mg when this method was used.

• 한국지역사회생활과학회지
• /
• 제28권3호
• /
• pp.391-401
• /
• 2017

This study was conducted to evaluate the relationships between exposure level to pyrethroid pesticide and wearing of protective equipment in 194 Chung-nam orchard male farmers. The urinary metabolites of pyrethroid pesticides, including Cis, Trans, DBCA, and 3-PBA, were analyzed by GC/MSD. As a result of this study, the detection rate and exposure level of 3-PBA was the highest among pyrethroid metabolites discovered by orchard farmers. As a result of analyzing the actual conditions of wearing protective equipment by the subjects of this study, the rate of agricultural farmers who wore four pieces of protective equipment compared to agricultural farmers wearing a single piece of protective clothing was as high as 35.1%. Pyrethroid exposure levels were low when farmers wore more personal protective equipment (PPE). In conclusion, training with regards to pesticide hazards and protective equipment for farmers who spray pesticides will help reduce pesticide exposure levels.

• 농약과학회지
• /
• 제19권1호
• /
• pp.41-46
• /
• 2015

본 연구는 상대적으로 농약을 많이 살포하는 고랭지 배추 농작업자를 대상으로 피레스로이드계 살충제의 노출에 영향을 미치는 요인을 생물학적 모니터링을 이용하여 평가하기 위하여 수행되었다. 강원도 고랭지 배추 작업을 하는 농업인을 대상으로 하여 농약 살포 다음날 아침 첫 소변을 받아서 요중 cis-, trans-DCCA, DBCA를 분석하였다. 농약 노출에 영향을 미칠 수 있는 요인으로는 풍속, 살포 위치, 보호구 착용 등을 조사하였다. 통계분석은 Kruskall Wallis로 시행하였다. 분석 결과, 고랭지 배추 작업자는 일반인보다 농약에 대한 노출이 많았으며, 풍속이 낮은 경우에는 살포자가 더 많이 노출되지만, 풍속이 높은 경우에는 살포자와 보조자간의 차이가 없었다.

• 한국환경과학회지
• /
• 제12권8호
• /
• pp.891-896
• /
• 2003

The objectives of this study wre to investigate the effects of two synthetic pyrethroids, bifenthrin(BF) and permethrin(PM), in runoff and to evaluate the effects of suspended solids (SS) in the transport of pyrethroid along the drainage channel. Monitoring of BF and PM was conducted with the runoffs as well as in sediments existing along the drainage channel at a nursery site located in southern California, USA. This study also suggests Best Management Practices (BMPs) to alleviage the pollution caused by heavy usage of pyrethroid insecticides at nursery sites. Due to a high affinity to solid particles of pyrethroid insecticides, the concentrations of BF and PM were proportional to the SS contents along the drainage channel. This study suggests that alleviation of pyrethroids existing in runoffs could be controlled by the removal of suspended solids in runoffs and potential implications of current drainage channels for mitigation of pesticides associated with runoffs.

• Food Science and Biotechnology
• /
• 제15권1호
• /
• pp.57-62
• /
• 2006

Six organophosphorus, one organochlorine, and three synthetic pyrethroid pesticides were analyzed for their residues during washing and hot-air drying of red peppers conducted in the production of powder. The residue ratio in organophosphorus pesticides was 33% in chlorpyrifos, 31 % in diazinon, 50% in methidathion, 80% in EPN, 28% in fenitrothion, and 60% in profenofos. The ratio in pyrethroids was 109% in cypermethrin, 102% in deltamethrin, and 106% in fenvalerate. That in organochlorine was 56% in ${\alpha}$-endosulfan and 90% in ${\beta}$-endosulfan. The results were greatly different between organophosphorus and pyrethroid pesticides. UV irradiation along with hot-air drying brought about a remarkable reduction of the residues, up to 70% as compared with hot-air drying only. The removal effect was most remarkable in pyrethroids, which are hardly removed by hot-air drying. The color of the pepper was not changed during UV irradiation. The use of oxidizing agents such as hydrogen peroxide or chlorine dioxide during washing did not show a remarkable removal of residues. The residue ratio was not affected whether the pesticide is contaminated artificially or naturally.

• 한국환경보건학회지
• /
• 제47권3호
• /
• pp.245-258
• /
• 2021

Objectives: In many previous studies, endocrine disruptors (EDCs) have been found to affect delays in puberty. Various EDCs have been reported on, but there have been only limited epidemiologic studies on the effects of exposure to environmental heavy metals and pyrethroid pesticides on puberty delay. Therefore, the aim of this study was to investigate the association of exposure to environmental mercury, cadmium, and pyrethroid pesticides with delayed puberty in children based on national survey data that represents Korean children. Methods: We selected 450 children at the ages of 9-11 years old from the third Korean National Environmental Health Survey (3rd KoNEHS). The relations of urinary Hg, Cd, and 3-PBA with pubertal development were evaluated using multiple logistic regression analyses. Results: Urinary Hg levels were significantly associated with delayed puberty in boys [testicle development: OR=0.41 (95% CI: 0.20, 0.84); genitalia development: OR=0.35 (95% CI: 0.15, 0.81)]. Girls with higher Hg levels were more likely to experience delayed menarche [OR=0.23 (95% CI: 0.06, 0.90)]. We observed a significant 49% reduction in odds for menarche per increasing unit of urinary cadmium levels [OR=0.51 (95% CI: 0.24, 1.01)]. In addition, urinary 3-PBA showed a negative association with genitalia development in boys and menarche in girls [genitalia development: OR=0.73 (95% CI: 0.55, 0.96); menarche: OR=0.56 (95% CI: 0.32, 1.00)]. Conclusions: The results of this study support the hypothesis that exposure to environmental mercury, cadmium and pyrethroid pesticides may affect puberty delays. Additional evidence needs to be obtained through further prospective studies.

• 한국지하수토양환경학회:학술대회논문집
• /
• 한국지하수토양환경학회 2002년도 추계학술발표회
• /
• pp.81-85
• /
• 2002

The possibility of simultaneous analysis of 24 pesticides out of 30 residual pesticides which are subjected to test in the golf courses was examined. The utility of the simultaneous analysis of multi-residue pesticides was evaluated by recovery test through a standard addition method of pesticides in water, soil, and lawn grass. The experimental results of the recovery rates for individual pesticides are as follows : The number of pesticide of which average recovery was over 70% regardless of medium was 16 pesticides. These pesticides were composed of 8 organophosphorus pesticides(Chlorpyrifos, Chlorpyrifos-methyl, Diazinon, EPN, Fenitrothion, Phenthoate, Phosalone, and Toclofos-methyl). 4 organochlorinated pesticides(Daconil, Captan, Endosulfan, and Tetradifon), 2 pyrethroid pesticides(Fepropathrin, Lambda-cyhalothrin) and 2 other pesticides(Bromopropylate, Pendimethalin). On the other hand, in case of Dicofol, average recovery by medium was over 70% for water and lawn grass but was only 53.3% for soil. Therefore, the simultaneous analytical method applied in this experiment is not appropriate for analysis of Dicofol in soil. Furthermore, among 7 pesticides, 2 pesticides(Amitraz and Pyraclofos) showed that theirs average recovery rates deviated from criteria(70~130%) at almost all media, while 5 pesticides(Bensulide, Deltamethrin, Iprodione, Phosphamidon and Tralomethlin) were not detected from all media by selected GC detector(NPD or ECD).

• 한국독성학회:학술대회논문집
• /
• 한국독성학회 2003년도 추계학술대회
• /
• pp.149-149
• /
• 2003

It is well known that many pesticides possess hormonal activity, and thus have been classified as endocrine disruptors. Currently, pyrethroid insecticides are in worldwide use to control in door pests, providing potential for environmental exposure. A few studies of hormonal activities of these pyrethroid insecticides, however, have been reported, and are controversial between studies.(omitted)

• Environmental Analysis Health and Toxicology
• /
• 제30권
• /
• pp.9.1-9.5
• /
• 2015

Objectives Pyrethroid pesticides are among the most commonly using insecticides in South Korean households and have been the subject of considerable interest among public health professionals for their potential health effects. The objective of this study is to examine the level of urinary 3-phenoxybenzoic acid (3-PBA) among elementary students in South Korea. Methods We conducted a cross-sectional study to evaluate pyrethroid pesticide exposure levels by measuring the urinary metabolites of 3-PBA using a gas chromatographymass spectrometry method in March 2011. Study participants were 70 Asan-area and Incheon-area elementary students. Results All respondents had values above the detection limit, and the geometric means of 3-PBA in all children were $1.85{\mu}g/L$ and $1.46{\mu}g/g$ creatinine. Children with the top 10% urinary levels of 3-PBA were more likely to be girls, under nine years of age, living in a rural area, and living in a residential type apartment. Conclusions South Korean children have a higher concentration of urinary 3-PBA compared with those of other countries. Further research identifying exposure pathways and intervention efforts to reduce environmental pesticide use are needed in South Korea.

• 한국환경독성학회:학술대회논문집
• /
• 한국환경독성학회 2003년도 추계국제학술대회
• /
• pp.57-69
• /
• 2003

It is well known that many pesticides possess hormonal activity, and affect the developments of wildlife and mammals including human. Currently, pyrethroid insecticides are in worldwide use to control in and outdoor pests, providing potential far environmental exposure. Hormonal activities of these pyrethroid insecticides, however, have been little studied, and the developmental effects of them were no reported. Therefore, we firstly examined the potential estrogenic activities of some pyrethroid insecticides (permethrin, cypermethrin, tetramethrin, deltamethrin, sumithrin, fenvalerate and bioallethrin) by immature rat uterotrophic assay, luciferase reporter gene assay and Calbindin-D$\sub$9k/ (CaBP-9k) gene expression assay. Uterine wet weights were increased by permethrin and the permethrin-induced weights were inhibited by ICI 182780 in the uterolrophic assay. On the other hand tetramethrin significantly reduced uterine and vaginal wet weights, and also inhibited the E2-induced weight increases at all doses tested. Cypermethrin and sumithrin had a tendency to increase uterine weights, although not statistically significant. Permethrin and cypermethrin dose-dependently increased the luciferase activity in reporter gene assay. Northern blot analysis showed that permethrin induced CaBP-9k mRNA expression whereas tetramethrin inhibted. Subsequent studies were conducted to investigate the possible developmental effects of four pyrethroid insecricides (permethrin, cypermethrin, sumithrin and teramethrin). Either diethlbestrol (DES) or 17${\beta}$ -estradiol (E2) was used as a reference control in this study. Pyrethroid insecticides were administered to Sprague Dawley rats via subcutaneous injection at 6 to 18 days of gestation or 1 to 5 days after birth. In utero treatment of permethrin (10mg/kg/day) in female rat resulted in significant increases in uterine and ovarian weights while significant decreases in serum E2 concentration, uterine and ovarian ER${\alpha}$ mRNA levels. Sumithrin and permethrin led to acceleration in vaginal opening of female rat, while delay in preputial separation of male after neonatal treatment. Anogenital distances of PND 18 were significantly reduced in sumthrin-treated, and permerhrin-treated male rats after neonatal treatment. All the pyrethroid insecticides tested caused significant increases in uterine weights on PND 18, while significant reductions in the first diestrus phase when neonataly treated. In addition, exposure to pyrethroids in neonatal period led to significant reduction in relative brain weight in female rat on PND 18, but its weight was recovered in diestrus phase. In summary, Our experimental data demonstrate the possibilities of developmental effects of pyrethroid insecticides via estrogenic or antiestrogenic activity.