Proceedings of the Korea Society of Environmental Toocicology Conference (한국환경독성학회:학술대회논문집)
- 2003.10a
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- Pages.57-69
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- 2003
Estrogenic Activity, and Developmental Toxicity Studies of Pyrethroid Insecticides
- Kim, Soon-Sun (Division of reproductive and developmental toxicology, National Institute of Toxicological, Research, Korea FDA) ;
- Rhee, Gyu-Seek (Division of reproductive and developmental toxicology, National Institute of Toxicological, Research, Korea FDA) ;
- Lee, Rhee-Da (Division of reproductive and developmental toxicology, National Institute of Toxicological, Research, Korea FDA) ;
- Kwack, Seung-Jun (Division of reproductive and developmental toxicology, National Institute of Toxicological, Research, Korea FDA) ;
- Lim, Kwon-Jo (Division of reproductive and developmental toxicology, National Institute of Toxicological, Research, Korea FDA) ;
- Yhun, Hyo-Jung (Division of reproductive and developmental toxicology, National Institute of Toxicological, Research, Korea FDA) ;
- Park, Kui-Lea (Division of reproductive and developmental toxicology, National Institute of Toxicological, Research, Korea FDA)
- Published : 2003.10.01
Abstract
It is well known that many pesticides possess hormonal activity, and affect the developments of wildlife and mammals including human. Currently, pyrethroid insecticides are in worldwide use to control in and outdoor pests, providing potential far environmental exposure. Hormonal activities of these pyrethroid insecticides, however, have been little studied, and the developmental effects of them were no reported. Therefore, we firstly examined the potential estrogenic activities of some pyrethroid insecticides (permethrin, cypermethrin, tetramethrin, deltamethrin, sumithrin, fenvalerate and bioallethrin) by immature rat uterotrophic assay, luciferase reporter gene assay and Calbindin-D
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