• Title/Summary/Keyword: Pump system

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Effect of Selenium on the Thyroid gland Antioxidative Metabolisms in Rat Model by Ionizing Radiation (셀레늄이 전리방사선에 의한 힌쥐 모델에서의 갑상선 항산화계에 미치는 영향)

  • Choi, Hyung-Seok;Choi, Jun-Hyeok;Jung, Do-Young;Kim, Jang-Oh;Shin, Ji-Hye;Min, Byung-In
    • Journal of radiological science and technology
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    • v.40 no.1
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    • pp.135-142
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    • 2017
  • Selenium (Se), which is natural materials existing was known as an important component of selenoprotein, one of the important proteins responsible for the redox pump of a living body. Selenium was orally administered to Rat and irradiated with 10 Gy of radiation. Then, the thyroid gland was used as a target organ for 1 day, 7 days and 21 days to investigate the radiation protection effect of selenium (Se) through changes of blood components, thyroid hormones (T3, T4), antioxidant enzyme (GPx) activity and thyroid tissue changes. As a result, there was a significant protective effect of hematopoietic immune system(hemoglobin concentration, neutrophil, platelet)(p<0.05). The activity of Glutathione Peroxidase (GPx), the antioxidant enzyme, and the activity of the target organ, thyroid hormone (T3, T4), also showed significant activity changes (p<0.05). In the observation of tissue changes, it was confirmed that there was a protective effect of thyroid cell damage which caused the cell necrosis by radiation treatment. Therefore, it is considered that selenium(Se) can be utilized as a radiation defense agent by inducing immunogenic activity effect of a living body.

Analysis of High-Resolution Manometry Results in LPRD Patients Who Do Not Response to PPI Medication (양자펌프 억제제에 반응을 보이지 않은 인후두 역류질환 환자에서 고해상도 식도 내압검사의 분석)

  • Lee, Chang-Hee;Lee, Hyun-Sub;Jin, Sung-Min;Lee, Sang-Hyuk
    • Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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    • v.23 no.1
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    • pp.43-47
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    • 2012
  • Background and Objectives : Laryngopharyngeal reflux disease (LPRD) originates from regurgitation of gastric contents to the laryngopharynx, and it is relatively common disease in otolaryngology. Proton-pump inhibitor (PPI) medication is frequently using treatment method in present time, but controversies exist regarding treatment for it. High-resolution manometry (HRM) system is a newly developed device that using 36 channels and pressure topography plotting program, checking the function and status of esophagus. The aim of this study was to evaluate clinical usefulness of HRM in LPRD patients who do not response to PPI medication. Materials and Method : From July 2009 to July 2010, a total of 99 patients who were suspected LPRD according to symptoms (Reflux Symptom Index >13) and laryngoscopic findings (Reflux Finding Score >7) were retrospectively enrolled in this study. Patients were consisted of 31 men and 68 women, the mean age was 51.8 years, the mean BMI was 22.46. Patients have taken PPI medication for 2 months, after medication, they performed HRM. Comparative analysis was performed with results of the difference in symptoms. Results : In 99 patients, 37 patients (37.4%) show not improvement of LPRD symptoms after PPI medication. Among them, 18 patients (48.6%) showed abnormal findings that were classified as Peristaltic dysfunction (38.9%), Diffuse esophageal spasm (11.1%), Relaxation impairment of LES (11.1%), Achalasia (5.6%), Hypotensive LES (11.1%), Relaxation impairment of UES (11.1%), Nutcracker esophagus (5.6%), Decreased resting pressure (5.6%). Other 62 patients (62.6%) show improvement of LPRD symptoms, 23 patients (37.1%) showed abnormal findings. Most common finding was Peristaltic dysfunction (43.4%) More prevalent abnormal findings of HRM were found in patients who revealed no response to PPI medication (48.6% vs. 37.1%), but it does not reach the statistical significance. Conclusion : Although statistical significances is not showed, the difference observed in the frequency of HRM abnormal finding between response and no response for PPI medication. It has been estimated that HRM may be used to determine differential diagnosis in patients with LPRD. Further studies in lager population containing normal controls will be needed to prove clinical usefulness.

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Analysis of High-Resolution Manometry Results in LPRD Patients who do not Response to PPI Medication (양자펌프 억제제에 반응을 보이지 않은 인후두 역류질환 환자에서 고해상도 식도 내압검사의 분석)

  • Lee, Chang-Hee;Lee, Hyun-Sub;Jin, Sung-Min;Lee, Sang-Hyuk
    • Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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    • v.22 no.2
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    • pp.151-155
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    • 2011
  • Background and Objectives : Laryngopharyngeal reflux disease (LPRD) originates from regurgitation of gastric contents to the laryngopharynx, and it is relatively common disease in otolaryngology. Proton-pump inhibitor (PPI) medication is frequently using treatment method in present time, but controversies exist regarding treatment for it. High-resolution manometry (HRM) system is a newly developed device that using 36 channels and pressure topography plotting program, checking the function and status of esophagus. The aim of this study was to evaluate clinical usefulness of HRM in LPRD patients who do not response to PPI medication. Subjects and Method : From July 2009 to July 2010, a total of 99 patients who were suspected LPRD according to symptoms (Reflux Symptom Index >13) and laryngoscopic findings (Reflux Finding Score >7) were retrospectively enrolled in this study. Patients were consisted of 31 men and 68 women, the mean age was 51.8 years, the mean BMI was 22.46. Patients have taken PPI medication for 2 months, after medication, they performed HRM. Comparative analysis was performed with results of the difference in symptoms. Results : In 99 patients, 37 patients (37.4%) show not improvement of LPRD symptoms after PPI medication. Among them, 18 patients (48.6%) showed abnormal findings that were classified as Peristaltic dysfunction (38.9%), Diffuse esophageal spasm (11.1%), Relaxation impairment of LES (11.1%), Achalasia (5.6%), Hypotensive LES (11.1%), Relaxation impairment of UES (11.1%), Nutcracker esophagus (5.6%), Decreased resting pressure (5.6%). Other 62 patients (62.6%) show improvement of LPRD symptoms, 23 patients (37.1%) showed abnormal findings. Most common finding was Peristaltic dysfunction (43.4%) More prevalent abnormal findings of HRM were found in patients who revealed no response to PPI medication (48.6% vs. 37.1%), but it does not reach the statistical significance. Conclusion : Although statistical significances is not showed, the difference observed in the frequency of HRM abnormal finding between response and no response for PPI medication. It has been estimated that HRM may be used to determine differential diagnosis in patients with LPRD. Further studies in lager population containing normal controls will be needed to prove clinical usefulness.

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Basic performance analysis of ocean thermal energy conversion using the refrigerant mixture R32/R152a (R32/R152a 혼합냉매를 적용한 해양온도차발전의 기초성능해석)

  • Cha, Sang Won;Lee, Ho Saeng;Moon, Deok Soo;Kim, Hyeon Ju
    • Journal of Advanced Marine Engineering and Technology
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    • v.38 no.4
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    • pp.502-507
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    • 2014
  • In this paper, performance characteristics of cycles were studied when mixed working fluid was used for ocean thermal energy conversion (OTEC). Among the various mixed refrigerants for industrial heat-pump, R32/R152a used in ocean thermal energy conversion system. For simulations, R32/R152a were used in existing closed cycle and Kalina cycle which is used only ammonia and water as mixed refrigerant. Temperature of the warm heat source was 26 and 29 celsius degree, temperature of the cold heat source was 5 celsius degree. In results of simulation, Gross power of the closed cycle on R32 was 22kW, and efficiency of the cycle was 2.02%. When the mixed refrigerant of R32/R152a, in the ratio of 90 to 10, gross power of the closed cycle was 29.93kW, and efficiency of the cycle was 2.78%. Gross power and cycle efficiency of R32/R152a increased by 36% and 37% than those of existing single refrigerant. Additionally, the same simulations were conducted in Kalina cycle with the same various composition ratio of mixed refrigerant.

Study on the Measurement of TMP Pumping Speed (터보분자펌프(TMP) 배기속도 측정에 관한 고찰)

  • Kang, S.B.;Shin, J.H.;Cha, D.J.;Koh, D.Y.;Cheung, W.S.;Lim, J.Y.
    • Journal of the Korean Vacuum Society
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    • v.19 no.4
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    • pp.249-255
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    • 2010
  • Methods of the characteristics evaluation of turbo-molecular pumps (TMP) are well-defined in the international measurement standards such as ISO, PNEUROP, DIN, JIS, and AVS. The Vacuum Center in the Korea Research Institute of Standards and Science (KRISS) has recently designed, constructed, and established the integrated characteristics evaluation system of TMPs based on the international documents by continuously pursuing and acquiring the reliable international credibility through measurement perfection. The measurement of TMP pumping speed is normally performed with the throughput and orifice methods dependent on the mass flow regions. However, in the UHV range of the molecular flow region, the high uncertainties of the gauges, mass flow rates, and conductance are too critical to precisely accumulate reliable data. In order to solve the uncertainty problems of pumping speeds in the UHV range, we introduced a SRG with 1% accuracy and a constant volume flow meter (CVFM) to measure the finite mass flow rates down to $10^{-1}$ Pa-L/s with 3% uncertainty for the throughput method. In this way we have performed the measurement of pumping speed down to $10^{-4}$ Pa with an uncertainty of less than 6% for a 1000 L/s TMP. In this article we suggest that the CVFM has an ability to measure the conductance of the orifice experimentally with flowing the known mass through the orifice chambers, so that we may overcome the discontinuity problem encountering during introducing two measurement methods in one pumping speed evaluation sequence.

Comparison of the Gel Formation Ability and Stability of Encapsulated Microbial Inoculant Using Extractable Alginate from Sea Tangle (다시마 추출 Alginate를 이용한 미생물 캡슐화제의 겔 형성능 및 생균력 비교)

  • Choi, So-Young;Yoon, Min-Ho;Whang, Kyung-Sook
    • Applied Biological Chemistry
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    • v.49 no.3
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    • pp.170-174
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    • 2006
  • For the purpose of developing a high quality agricultural microbial inoculant, methods and materials for improving encapsulation were investigated. Preparation of capsule was conducted by improving extrusion system with micro-nozzle and peristaltic pump. The sodium alginate was selected because of its cheapness, stability of cells, and gel formation ability. The yields, physical properties and gel formation abilities of extractable alginate from sea tangle were investigated by hot water extractable and alkali soluble methods. The extraction yields of hot water extractable alginate (HWEA) and alkali soluble alginate (ASA) from sea tangle were 8 and 20%, respectively. The HWEA was almost not viscous even in 1.5% of the sample solution, whereas the ASA was very highly viscous in above 3% sample solution. The gel formation ability of each samples varied from 1.5% to 5% and the ASA showed a good gel formation ability at 3% solution as commercial alginate (CA). The soil microbial inoculant, Bacillus thuringiensis, Bacillus subtilis, Lactobacillus plantarum and Geotrichum candidum encapsulated sodium alginate with starch and zeolite for stabilizer. The survivability of encapsulated soil microbial inoculant using alginate without stabilizer appeared to be 66, 52, 70 and 50%, respectively. Inclusion of starch and zeolite with alginate bead increased viabilities in Bacillus sp. and Geotrichum candidum by 81-83% and 89%, respectively.

Water Supply Alternatives for Drought by Weather Scenarios Considering Resilience: Focusing on Naju Reservoir (회복탄력성을 고려한 기상 시나리오별 가뭄 용수 공급방안: 나주호를 중심으로)

  • Park, JinHyun;Go, JeaHan;Jo, YoungJun;Jung, KyungHun;Sung, MuHong;Jung, HyoungMo;Park, HyunKyu;Yoo, SeungHwan;Yoon, KwangSik
    • Journal of The Korean Society of Agricultural Engineers
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    • v.60 no.5
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    • pp.115-124
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    • 2018
  • Resilience has been widely used in various fields including design and operation of infrastructures. The resilient infrastructures not only reduce the damage scale of various disasters but also reduce the time and cost required for restoration. However, resilience rarely applied to promote efficient management of agricultural infrastructures. Recently, drought is an aggravating disaster by climate change and need countermeasures. Therefore, we tried to demonstrate evaluating measures in case of drought under consideration of resilience. This study applied the robustness-cost index (RCI) to evaluate alternative solution of the supply problem of a large agricultural reservoir under drought conditions. Four structural alternatives were selected to estimate the robustness index (RI) and the cost index (CI) to obtain the RCI values. Structural alternatives are classified into temporary measures and permanent measures. Temporary measures include the development of a tube wells and the installation of the portable pump, while the permanent measures include the installation of a pumping stations and the pumping water to the reservoir (Yeongsan River-Naju reservoir). RCI values were higher in permanent measures than those of temporary measures. Initial storage of the reservoir also affected RCI values of the drought measures. Permanent measures installation and management of early stage of the reservoir storage shortage was identified as the most resilient system.

Encapsulation of Agro-Probiotics for Promoting Viable Cell Activity (생균력 증진을 위한 농업용 미생물제 미세캡슐화)

  • Choi, So-Young;Yoon, Min-Ho;Whang, Kyung-Sook
    • Korean Journal of Soil Science and Fertilizer
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    • v.38 no.5
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    • pp.287-293
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    • 2005
  • In this work, to develop soil inoculant which maintains stable viable cells and normalized quality, studies on micro-encapsulation with bacteria and yeast cells were performed by investigating materials and methods for micro-encapsulation as well as variation and stability of encapsulated cells. Preparation of capsule was conducted by application of extrusion system using micro-nozzle and peristaltic pump. K-carragenan and Na-alginate were selected as best carrier for gelation among K-carageenan, Na-alginate, locust bean gum, cellulose acetate phthalate (CAP), chitosan and gelatin tested. Comparing the gels prepared with Bacillus sp. KSIA-9 and carriers of 1.5% concentration, although viable cell of K-carragenan and Na-alginate was six times higher than those of other, Na-alginate was finally selected as carrier for gelation because it is seven times cheaper than K-carragenan. The gel of 1.5% Na-alginate was also observed to have the best morphology with circular hardness polymatrix and highest viable cell. When investigating the stability of encapsulated cells and the stabilizer effect, free cells were almost dead within 30 or 40 days whereas encapsulated cells decreased in 10% after 30 days and 15-30% even after 120 days. As stabilizer for maintaining viable cell, both 1% starch and zeolite appeared to possess the level of 70-80% cell for bacteria and yeast until after 120 days.

Cause Analysis for Reduced Effect of Sewer Pipe Improvement Project Based On Investigation of Interceptor Sewers (차집관로의 조사 및 분석을 통한 하수관로정비 사업의 효과 감소 원인 분석)

  • Chae, Myungbyung;Bae, Younghye;Kim, Hungsoo
    • Journal of Wetlands Research
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    • v.20 no.3
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    • pp.219-226
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    • 2018
  • Interceptor sewer is installed underground near to the river side mostly ofstate-owned land and the management efficiency of public sewage disposal facilities is decreasing as too much infiltration/inflow(I/I) and river flow to interceptor sewer are caused by broken or deteriorated sewer. This also affects the sewer pipeline project and decreases its efficiency. Therefore, the aim of this study is to investigate interceptor sewer which has influence on the reduction of the project effect. The investigation were performed for three study areas. The study includes the investigation of current condition of interceptor sewer(sewer extension, pipe diameter, pipe type, installed year, installed locations, etc), investigation of inside of sewer by CCTV accompanied by pumping and dredging works where required, investigation of inside of manholes by eyes, calculation of pollutant load using the results of investigation of flow quantity and quality. Multipoint investigations were simultaneously performed for flow quantity at confluence area and other investigations were also performed for flow quantity and BOD for interceptor sewer and comparison of pollutant load, investigation of infiltration/inflow(I/I) caused by deterioration of interceptor sewer. As the result of the study, a main reason for reduced effect of sewer pipe improvement project was analyzed as the low-density sewage and I/I in public seweage treatment Facility due to deteriorated and unmanaged interceptor sewers.

GIS spatial D/B formation of geothermal data and Distribution of Heat Flow of Korea (한국의 지열자료 GIS 공간 D/B 구축과 지열류량 분포)

  • Kim, Hyoung-Chan;Lee, Young-Min;Park, Jeong-Min
    • 한국신재생에너지학회:학술대회논문집
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    • 2006.06a
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    • pp.459-460
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    • 2006
  • 현재 남한의 지열류량 측정값으로는 총 363개 지점의 자료가 측정 및 수집되어 있다. 이것은 Mizutani et at. (1970), 장정진 외(1970), 그리고 서정희(1976) 등의 자료, 총 35개의 자료도 추가된 것이다. 1989년 이후부터 측정된 지열류량 자료는 217개 자료이며(임정웅 외, 1989; 임정웅 외, 1996; Lim and Kim, 1997; 염병우 외, 1997), 모두 직접 측정한 것이나, 1989년 이후 보고된 지열류량 자료에 약간의 오류가 있어 이번 연구에서 수정 보완하였다. 또한 과거의 자료 35개 자료는 이미 지열류량 측정치가 논문화 되어 있는 것으로 암석시료는 없다 1989년 이후 2004년까지 자료 217개 2005년도 추가 자료 111개의 지열류량 자료는 암석시료도 있으며, 측정기기가 서로 달라 오차가 있을 수 있어 서로 보정을 해야 할 필요가 있어 시추공 주변 암석을 새로 수집해서 신장비로 다시 측정 보정하였다. 지열류량 D/B 구축은 각 자료의 일련번호, 고유번호 (Sn.), 위경도 좌표 (longitude, lattitude), 암석의 열전도도(thermal conductivity), 지온경사 (thermal gradient), 지열류량 (heat flow)등으로 구성되어 있다. 지열류량 자료 공간 데이터베이스는 점 속성을 가지며 자료형태는 각종 소프트웨어와 호환성이 좋은 shape 파일 형태로 작성하였다. 또만 최근 천부 토양 및 암석 열물성을 이용한 냉난방시스템 즉, Heat Pump System 설계를 위하여 반드시 들어가야 하는 요소인 열확산율, 공극율, 밀도, 비열 등 열물성 특성을 추가하여 GIS 공간 D/B구축하였다. 대륙붕 자료 4개 자료를 제외하고 359개의 지열류량 자료를 이용하여 한반도 남부, 즉 남한의 지열류량 분포도를 작성 분석해 본 결과(그림 1), 우리나라의 지열류량 이상대는 아산만 주변, 보령, 유성, 진안, 울진, 포항, 부산 지역과 포천, 속초, 충주, 수안보 등 지역에서 나타난다 이러한 이상대 주변에는 대개 온천이 발달되어 있었거나 새로 개발되어 있는 곳이다. 온천에 이용하고 있는 시추공의 자료는 배제하였으나 온천이응으로 직접적으로 영향을 받지 않은 시추공의 자료는 사용하였다 이러한 온천 주변 지역이라 하더라도 실제는 온천의 pumping 으로 인한 대류현상으로 주변 일대의 온도를 올려놓았기 때문에 비교적 높은 지열류량 값을 보인다. 한편 한반도 남동부 일대는 이번 추가된 자료에 의해 새로운 지열류량 분포 변화가 나타났다 강원 북부 오색온천지역 부근에서 높은 지열류량 분포를 보이며 또한 우리나라 대단층 중의 하나인 양산단층과 같은 방향으로 발달한 밀양단층, 모량단층, 동래단층 등 주변부로 NNE-SSW 방향의 지열류량 이상대가 발달한다. 이것으로 볼 때 지열류량은 지질구조와 무관하지 않음을 파악할 수 있다. 특히 이러한 단층대 주변은 지열수의 순환이 깊은 심도까지 가능하므로 이러한 대류현상으로 지표부근까지 높은 지온 전달이 되어 나타나는 것으로 판단된다.

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