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A Review on Reporting Quality of Acupuncture Intervention for Visceral Pain: Assessment with STRICTA (내장 통증에 사용된 침 중재 분석 및 보고의 질 평가)

  • Lee, In-Seon;Cheon, Soyeon;Park, Ji-Yeun
    • Korean Journal of Acupuncture
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    • v.36 no.1
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    • pp.19-35
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    • 2019
  • Objectives : The purpose of this study is to review which acupoints and meridians are selected to treat visceral pain in articles published in international journals and to investigate quality of reporting acupuncture intervention according to the STRICTA guidelines. Methods : Electrical and hand search were conducted in PubMed, EMBASE, MEDLINE, and Cochrane Library for acupuncture studies on visceral pain in human and animals. Reporting quality of intervention was evaluated using the revised STRICTA guidelines. Results : We included 51 articles (7 clinical studies and 44 animal studies) in this study. The most frequently adopted meridians and acupoints were Stomach meridian, Spleen meridian, Conception Vessel meridian, and ST36, CV4, SP6, LI4, PC6, SP9, ST25, ST37 in clinical studies. In animal studies, Stomach meridian, Conception Vessel meridian, Pericardium meridian and ST36, ST37, CV12, PC6 were most frequently used. Animal studies showed significantly lower quality of reporting compared to clinical studies. According to the analysis on the effect of year of publication of articles, announcement of STRICTA guidelines did not improve the quality of reporting for studies on visceral pain. Conclusions : These results suggest that both proximal and distal acupoints based on meridian theory were used to study the underlying mechanisms of visceral pain both in human and animal studies. Guidelines of acupuncture intervention reporting for animal study is necessary to improve the quality of evidence, and it will also allow us the integrative understanding of the mechanisms and clinical effects of acupuncture treatment in human and animal.

Preventive Effects of Fluoride Gel Application on Dental Caries in the Permanent Tooth: A Systematic Review of Randomized Controlled Trials

  • Do, Kyung-Yi;Lee, Eun-Sun
    • Journal of dental hygiene science
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    • v.19 no.1
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    • pp.9-22
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    • 2019
  • Background: The purpose of this systematic review was to investigate the effects of topical fluoride gel application on dental caries prevention in the permanent teeth of children and adolescents. Methods: We searched the EMBASE, PubMed, and Cochrane Library databases for randomized controlled trials (RCTs) assessing the effects of self-applied or professionally applied topical fluoride gels in patients <18 years of age; the search was completed on April 1, 2018. All included trials involved an experimental group (fluoride gel application) and a control group (placebo or no treatment). The outcome measures were the D(M)FS and D(M)FT indices, which were compared between the two groups. Review Manager software was used for quantitative synthesis of the final selected articles, and a forest plot was generated via a meta-analysis conducted using a random effects model. Results: The results showed that the D(M)FS and D(M)FT indices were lower in the fluoride application group than in the control group, thus indicating that fluoride gel application was effective in dental caries prevention. We also performed a subgroup analysis to determine whether the effects of fluoride application differed if patients received oral prophylaxis (self or professional) before fluoride gel application. Therefore, the two groups showed slightly larger differences when studies without oral prophylaxis before fluoride gel application were considered; however, the difference was not statistically significant. Conclusion: These findings should be utilized to raise awareness about the caries-prevention effects of topical fluoride application among patients and guardians. Further RCTs should evaluate the effects of fluoride application with or without preceding oral prophylaxis, and appropriate fluoride application guidelines should be developed to maximize the effects of fluoride application in clinical practice.

Clinical Effectiveness of Acupuncture in the Treatment of Non-Alcoholic Fatty Liver Disease: A Systematic Review (비알코올성 지방간 질환에 대한 침치료의 효과 : 체계적 고찰)

  • Hyun, Joon;Lee, Joo-bok;Kim, So-yeon;Han, Chang-woo
    • The Journal of Internal Korean Medicine
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    • v.39 no.6
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    • pp.1206-1224
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    • 2018
  • Purpose: This systematic review was planned and performed in order to determine the clinical effectiveness of acupuncture for non-alcoholic fatty liver disease (NAFLD). Methods: We searched related randomized controlled trials in several medical online databases, including China National Knowledge Infrastructure (CNKI), Excerpta Medica dataBASE (EMBASE), Public/Publisher MEDLINE (PubMed), Cochrane Central Register of Controlled Trials (CENTRAL), National Digital Science Library (NDSL), and Research Information Sharing Service (RISS). NAFLD related outcomes were extracted from the included trials and meta-analyzed. Results: From the 8 included trials, the values of the following examinations were extracted: liver ultrasonography, liver CT, body fat CT, aspartate transaminase (AST), alanine transaminase (ALT), gamma-glutamyltransferase (GGT), total cholesterol (TC), triglyceride (TG), low density lipoprotein (LDL) cholesterol, high density lipoprotein (HDL) cholesterol, fasting blood sugar (FBS), hosmeostatic model assessment for insulin resistance (HOMA-IR), weight, body mass index (BMI), waist hip ratio (WHR), obesity degree, body fat mass, body fat rate, leptin, malondialdehyde (MDA), and super oxide dismutase (SOD). In the 4 outcomes, cure rate in liver ultrasonography (RR=1.56; 95%CI=1.05~2.31; P=0.03), cure rate in liver CT (RR=2.23; 95%CI=1.33~3.72; P=0.002), TC (MD=-0.78; 95%CI=-1.41~-0.15; P=0.02), and TG (MD=-2.05; 95%CI=-3.88~-0.21; P=0.03), acupuncture was more effective than the control intervention. Conclusions: In this meta-analysis, acupuncture relieved hepatic steatosis, and reduced TC, and TG in NAFLD patients. more well-planned studies are still needed due to the heterogeneity and the considerable methodological flaws in the analyzed trials.

A study on the Heritage Documentation Programs of the United States (미국 문화유산 기록화 프로그램에 관한 연구)

  • Choi, Sun-young;Lee, Seung-hwi
    • The Korean Journal of Archival Studies
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    • no.49
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    • pp.77-119
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    • 2016
  • A modern architectural building is a cultural heritage, which is also part of our history until the present. Documentation is thus considered an irreplaceable method to preserve our cultural heritage as it may be the last resort of preservation. The study analyzed the Historic American Buildings Survey (HABS) on the Heritage Documentation Programs of the National Park Service. Based on the analysis of the comparison and documentation of the modern architectural building implemented by the Cultural Heritage Administration, the study suggested improvement plans from three different perspectives. First, specifically detailed regulations of the legal system are supposed to be used for the implementation of the documentation of modern architectural buildings. Second, it is suggested that a general plan for continuous documentation be made. Last, by setting up a collection method, an information service needs to be provided for the public.

A Lightweight Hardware Implementation of ECC Processor Supporting NIST Elliptic Curves over GF(2m) (GF(2m) 상의 NIST 타원곡선을 지원하는 ECC 프로세서의 경량 하드웨어 구현)

  • Lee, Sang-Hyun;Shin, Kyung-Wook
    • Journal of IKEEE
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    • v.23 no.1
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    • pp.58-67
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    • 2019
  • A design of an elliptic curve cryptography (ECC) processor that supports both pseudo-random curves and Koblitz curves over $GF(2^m)$ defined by the NIST standard is described in this paper. A finite field arithmetic circuit based on a word-based Montgomery multiplier was designed to support five key lengths using a datapath of fixed size, as well as to achieve a lightweight hardware implementation. In addition, Lopez-Dahab's coordinate system was adopted to remove the finite field division operation. The ECC processor was implemented in the FPGA verification platform and the hardware operation was verified by Elliptic Curve Diffie-Hellman (ECDH) key exchange protocol operation. The ECC processor that was synthesized with a 180-nm CMOS cell library occupied 10,674 gate equivalents (GEs) and a dual-port RAM of 9 kbits, and the maximum clock frequency was estimated at 154 MHz. The scalar multiplication operation over the 223-bit pseudo-random elliptic curve takes 1,112,221 clock cycles and has a throughput of 32.3 kbps.

Efficacy of topical interventions for temporomandibular disorders compared to placebo or control therapy: a systematic review with meta-analysis

  • Mena, Mariam;Dalbah, Lana;Levi, Lauren;Padilla, Mariela;Enciso, Reyes
    • Journal of Dental Anesthesia and Pain Medicine
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    • v.20 no.6
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    • pp.337-356
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    • 2020
  • This systematic review focused on the efficacy of topical products in reducing temporomandibular joint disorder (TMD)-associated pain, in comparison to placebo or control interventions. The EMBASE, Web of Science, Cochrane Library, and MEDLINE via PubMed databases were searched for randomized controlled trials (RCTs) using topical interventions in adults diagnosed with TMD. The pain intensity was the primary outcome, and other clinical findings were the secondary outcomes. The risk of bias was evaluated according to the Cochrane's handbook. The search up to February 7, 2020 identified a total of 496 unduplicated references. Nine RCTs with 355 adult patients diagnosed with TMD were included. The meta-analysis did not show a significant reduction in baseline pain intensity in the nonsteroidal anti-inflammatory drug (NSAIDs) group, when compared to the placebo group (P = 0.288). One study demonstrated a statistically significant pain score decrease for Theraflex-TMJ compared to placebo after 10 d of treatment (P = 0.003) and follow-up, 5 d after the last application (P = 0.027). Ping On reduced pain at 4 weeks of application (P < 0.001) but not after 7 d of application (P = 0.136). In one study, cannabidiol (CBD) significantly improved the pain intensity compared to placebo (P < 0.001). However, no differences were found with capsaicin in the two studies (P = 0.465). Evidence was of low quality because the studies were considered as having an unclear or a high risk of bias and a small number of studies were analyzed. The evidence is not sufficient to support the use of topical NSAIDs and capsaicin, and limited evidence was found for Threraflex-TMJ, bee venom, Ping On, and CBD, with only one study reporting for each. Additional studies are recommended to validate these results.

A Security SoC supporting ECC based Public-Key Security Protocols (ECC 기반의 공개키 보안 프로토콜을 지원하는 보안 SoC)

  • Kim, Dong-Seong;Shin, Kyung-Wook
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.24 no.11
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    • pp.1470-1476
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    • 2020
  • This paper describes a design of a lightweight security system-on-chip (SoC) suitable for the implementation of security protocols for IoT and mobile devices. The security SoC using Cortex-M0 as a CPU integrates hardware crypto engines including an elliptic curve cryptography (ECC) core, a SHA3 hash core, an ARIA-AES block cipher core and a true random number generator (TRNG) core. The ECC core was designed to support twenty elliptic curves over both prime field and binary field defined in the SEC2, and was based on a word-based Montgomery multiplier in which the partial product generations/additions and modular reductions are processed in a sub-pipelining manner. The H/W-S/W co-operation for elliptic curve digital signature algorithm (EC-DSA) protocol was demonstrated by implementing the security SoC on a Cyclone-5 FPGA device. The security SoC, synthesized with a 65-nm CMOS cell library, occupies 193,312 gate equivalents (GEs) and 84 kbytes of RAM.

Design of high-speed RSA processor based on radix-4 Montgomery multiplier (래딕스-4 몽고메리 곱셈기 기반의 고속 RSA 연산기 설계)

  • Koo, Bon-Seok;Ryu, Gwon-Ho;Chang, Tae-Joo;Lee, Sang-Jin
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.17 no.6
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    • pp.29-39
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    • 2007
  • RSA is one of the most popular public-key crypto-system in various applications. This paper addresses a high-speed RSA crypto-processor with modified radix-4 modular multiplication algorithm and Chinese Remainder Theorem(CRT) using Carry Save Adder(CSA). Our design takes 0.84M clock cycles for a 1024-bit modular exponentiation and 0.25M cycles for a 512-bit exponentiations. With 0.18um standard cell library, the processor achieves 365Kbps for a 1024-bit exponentiation and 1,233Kbps for two 512-bit exponentiations at a 300MHz clock rate.

Correlation between gray values of cone-beam computed tomograms and Hounsfield units of computed tomograms: A systematic review and meta-analysis

  • Selvaraj, Abirami;Jain, Ravindra Kumar;Nagi, Ravleen;Balasubramaniam, Arthi
    • Imaging Science in Dentistry
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    • v.52 no.2
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    • pp.133-140
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    • 2022
  • Purpose: The aim of this review was to systematically analyze the available literature on the correlation between the gray values (GVs) of cone-beam computed tomography (CBCT) and the Hounsfield units (HUs) of computed tomography (CT) for assessing bone mineral density. Materials and Methods: A literature search was carried out in PubMed, Cochrane Library, Google Scholar, Scopus, and LILACS for studies published through September 2021. In vitro, in vivo, and animal studies that analyzed the correlations GVs of CBCT and HUs of CT were included in this review. The review was prepared according to the PRISMA checklist for systematic reviews, and the risk of bias was assessed using the Quality Assessment of Diagnostic Accuracy Studies tool. A quantitative analysis was performed using a fixed-effects model. Results: The literature search identified a total of 5,955 studies, of which 14 studies were included for the qualitative analysis and 2 studies for the quantitative analysis. A positive correlation was observed between the GVs of CBCT and HUs of CT. Out of the 14 studies, 100% had low risks of bias for the domains of patient selection, index test, and reference standards, while 95% of studies had a low risk of bias for the domain of flow and timing. The fixed-effects meta-analysis performed for Pearson correlation coefficients between CBCT and CT showed a moderate positive correlation (r=0.669; 95% CI, 0.388 to 0.836; P<0.05). Conclusion: The available evidence showed a positive correlation between the GVs of CBCT and HUs of CT.

Analysis of the Utilization of Mobile Applications by Generation Z using Topic Modeling :Focusing on Users' Essay Data (토픽모델링을 활용한 Z세대의 애플리케이션 효용성에 대한 분석: 이용자의 에세이 데이터를 중심으로)

  • Park, Ju-Yeon;Jeong, Do-Heon
    • Journal of Industrial Convergence
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    • v.20 no.1
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    • pp.43-51
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    • 2022
  • The purpose of this study is to provide basic information necessary for the establishment of mobile service marketing strategies, educational service development, and engineering education for Generation Z by analyzing the utilitization of various applications by Gen Z. To this end, 177 essays on mobile service usage experience were collected, major topics were analyzed using topic modeling, and these were visualized through word cloud analysis. As a result of the study, the main topics were related to 'transportation' such as movement and public transportation, 'personal management' such as schedule management, financial management, food management, 'transaction' such as checkout, meeting, purchase, 'leisure' such as eating out, travel, study, culture. Additionally, words such as time, thought, people, life, bus, information, confirmation, payment, KakaoTalk, and so on were found to have a high of frequency of use. Also, there was found to be a difference between topics by college. This study is meaningful in that it collected essays, which are unstructured data, and analyzed them through topic modeling.