• Journal of Oriental Neuropsychiatry
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• v.15 no.1
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• pp.65-76
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• 2004

Alzheimer's disease(AD) is a geriatric dementia that is widespread in old ages. In the future AD will be the largest problem in public health service. From old times, much medicines have been used for treatment of dementia, but there is no medicine having obvious effects. AD is one of brain retrogression disease. So we studied on herbal medicine that have a relation for brain retrogression. From old times, in oriental medicine, senile disease such as dementia and AD is treated by exclusion of Tan(痰). But Vascular Dementia(VsD) is due to YuXue(瘀血). So in recent studies, Hua Xue Hua Yu(活血化瘀) medicine is used for precautionary and medical treatment. We studied on the effects for anti-Alzheimer in pCT105-induced neuroblastoma cell lines by Hyeolbuchukeo-tang(HCT). As the results of this study, in HCT group, the apoptosis in the nervous system is inhibited, the repair against the degeneration of Neuroblastoma cells by CT105 expression is promoted. These results indicate that HCT possess strong inhibitory effect of apoptosis in the nervous system and repair effect against the degeneration of neuroblastoma cells by CT105 expression.

• Journal of Oriental Neuropsychiatry
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• v.14 no.2
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• pp.95-105
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• 2003

Alzheimer's disease(AD) is a geriatric dementia that is widespread in old age. In the future AD will be the largest problem in public health service. From old times, Much medicines have been used for treatment of dementia, but there is no medicine having obvious effect. AD is one of brain retrogression disease. So We studied on herbal medicine that have a relation of brain retrogression. From old times, In Oriental Medicine, Radix Polygalae and Rhizoma Acori Graminei have been used for disease in relation to brain retrogression. We studied of anti-Alzheimer effect on CT105-induced neuroblastoma cell lines by Radix Polygalae(RP) and Rhizoma Acori Graminei(RAG) water extract. As the result of this study, In RP and RAG group, the apoptosis in the nervous system is inhibited, the repair against the degeneration of Neuroblastoma cells by CT105 expression is induced. These results indicate that In RP and RAG, RAG possess the strongest in inhibitory effect of apoptosis in the nervous system and repair effect against the degeneration of Neuroblastoma cells by CT105 expression.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.19 no.3
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• pp.253-262
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• 2007

Although the importance of good conservation of historical sites including ancient royal tombs is well aware, still not much attention has been paid for facilities to realize it. There are numerous ancient royal tombs spread in Korean peninsula which are opened and some of them are selectively on display for public access. However, the conservation measures of these sites have not been seriously investigated. Even the level of understanding of the underground environment of tombs is not satisfactory. In the present study, we focus on the dehumidification loads to maintain appropriate conservation conditions in terms of temperature and humidity. Two experimental tombs different in size were built in KNU (Kongju National University) campus with the dimensions ($L{\times}W{\times}H$) of $1.0m{\times}2.8m{\times}1.0m\;and\;1.3m{\times}3.0m{\time}1.2m$, respectively, HVAC systems are installed to maintain a suitable condition for conservation, i.e., $22{\pm}2^{\circ}C$ in temperature and $55{\pm}5%$ in relative humidity. The condensed water are measured to estimate the dehumidification loads while the temperature and the humidity inside the tombs were maintained within the specified range.

• Journal of Korea Planning Association
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• v.53 no.7
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• pp.109-126
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• 2018

The purpose of this study is to identify the spatial types for thermal environment improvement considering heat flux and its spatial context through empirical orthodox formulas. First, k-means clustering was used to classify values of three kinds of heat flux - latent, sensible and storage heat. Next, from the k-means clustering, we defined a type of thermal environment (type LHL) where improvement is needed for more comfortable and pleasant thermal environment in the city, among the eight types. Lastly, we compared and analyzed the characteristics of each classified thermal environmental types based on land cover types. From the study, we found that the ratio of impervious surfaces, roads, and buildings of the type LHL is higher than those of the type HLH (relatively thermal comfort environment). In order to improve the thermal environment, the following contents are proposed to urban planners and designers depending on the results of the study. a) Increase the green zone rate by 10% to reduce sensible heat; b) Reduce the percentage of impermeable surfaces and roads by 10% ; c) Latent heat increases when water and green spaces are expanded. This study will help to establish a minimum criterion for a land cover rate for the improvement of the urban thermal environment and a standard index for the thermal environmental improvement can be derived.

• Journal of the Korea Society of Computer and Information
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• v.27 no.3
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• pp.239-249
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• 2022

This study aims to analyze and compare the activating factors of domestic and overseas scuba diving resorts. Our delphi survey was conducted three times in 30 experts who involved in operation and management including scuba diving resort management representative and training team leader. As a result of comparing the activating factors at domestic versus overseas, it was found that common important activating factors included expansion of convenient facilities at public diving places, installation of safety and medical facilities for divers, development of first aid system including AED and oxygen ventilator, requirement of convenient facilities such as water lift and toilet in diving boat, installation of diving boat screw safety system, local boat operation guideline, regular course training program for scuba diving, employment of professional scuba diving instructor and guide, communication and promotion through various SNS portals, promotion by divers' word of mouth, involvement in regional Diving Resort Association, involvement in Korean Diving Association, communication and mutual benefit with local fishing villages, and linkage policy with local tourism industry.

• Journal of Radiation Protection and Research
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• v.46 no.2
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• pp.58-65
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• 2021

Background: The evaluation of skyshine distribution, release of airborne radioactive nuclides, and soil activation and groundwater migration were required for radiological assessment of the impact on the environment surrounding In-Flight (IF)-system facility of the RAON (Rare isotope Accelerator complex for ON-line experiment) accelerator complex. Materials and Methods: Monte Carlo simulation by MCNPX code was used for evaluation of skyshine and activation analysis for air and soil. The concentration model was applied in the estimation of the groundwater migration of radionuclides in soil. Results and Discussion: The skyshine dose rates at 1 km from the facility were evaluated as 1.62 × 10^-3 μSv·hr^-1. The annual releases of ³H and ¹⁴C were calculated as 9.62 × 10^-5 mg and 1.19 × 10^-1 mg, respectively. The concentrations of ³H and ²²Na in drinking water were estimated as 1.22 × 10^-1 Bq·cm^-3 and 8.25 × 10^-3 Bq·cm^-3, respectively. Conclusion: Radiological assessment of environmental impact on the IF-facility of RAON was performed through evaluation of skyshine dose distribution, evaluation of annual emission of long-lived radionuclides in the air and estimation of soil activation and groundwater migration of radionuclides. As a result, much lower exposure than the limit value for the public, 1 mSv·yr^-1, is expected during operation of the IF-facility.

• Journal of the Korean Society for Marine Environment & Energy
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• v.11 no.1
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• pp.55-62
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• 2008

This study investigated the status and problems of marine-related environmental impact assessment and a utilization-consultation system in Korea and suggested improvement of the review organization. Also, it conducted SWOT analysis based on evaluation of functions, roles and performance of the marine environmental impact assessment center and proposed development strategies of the center through introduction of expert opinions and advanced systems. The performance statement-review by the center in 2007 included 358 cases in total; 165 (46.1%) for consultation on utilization of sea area, 104 for environmental impact assessment (29.0%), and 89 (24.9%) for prior environmental review. The consultation on utilization of sea area can be divided into that for public water surface-use (41%) and reclamation (32%), and sea aggregate extraction process (21%). Although bad impacts on marine environment are reducing under the current system, there are some limits and problems to supplement it in terms of content, system and operation. Review system on sea area utilization-impact(marine environmental impact assessment center) by marine environmental management law needs to obtain expertise, fairness and efficiency and, to do so, have operational supports and institutional improvement to maximize its own functions and roles. At the same time, it is necessary for the center to establish identity and the status as a professional review organization by setting active development strategies inside the center. Finally, it should strengthen an consultation system of marine environmental impact assessment led by the related ministry to achieve effective coastal management.

• Journal of Advanced Marine Engineering and Technology
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• v.40 no.3
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• pp.152-156
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• 2016

Wastewater heat recovery heat pump systems use heated wastewater from public baths or factories as the heat pump's heat source. Generally, this system uses a bare tube evaporator. In the heat transfer process from wastewater to refrigerant, thermal resistance is caused primarily by fouling deposits on the outside surface of tube. Fouling directly increases thermal resistance and decreases heat pump efficiency. Thus, it is desirable to eliminate fouling. In this study, we fabricated a fouling mitigation device using a bubbling fluidized bed with cleaning sponge balls in the wastewater bath. Experimental conditions were as follows: $20^{\circ}C$ cold-water temperature, $40^{\circ}C$ wastewater temperature, 100 L/h cold water flow rate, and $0.161m^2$ heat exchanger surface area. Experimental results showed that the thermal resistance of fouling decreased by 56% with the fluidized bed alone and by 86% with both the fluidized bed and cleaning sponge balls.

• Journal of the Korean Society for Marine Environment & Energy
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• v.13 no.4
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• pp.327-334
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• 2010

The paper describes the history and the evolution of the conflict of the Saemangeum reclamation project, focusing on the court trial processes. The Saemangeum project is the world largest coastal reclamation work, regarded as the most controversial environmental issue in the recent history of Korea. Due to the severe pollution found in Lake Sihwa in 1996, the Saemangeum project began to receive a large degree of public concern on the water quality of the proposed artificial freshwater lake. Unlike the Sihwa case, the Korean court system intervened to resolve the heated conflicts between stakeholders in the Saemangeum case. Based on the same set of facts, the Korean courts showed different perspectives on the economic feasibility, value of the ecosystem, land use, and water quality, which represents the limit of legal system to address complicated environmental problems. After the final judgment by the Supreme Court, 'the Special Act for the promotion of the Saemangeum reclamation project', was enacted with strong political support from local leaders and congressmen. A more developmental-oriented land use plan came out in 2009 based on this Act. The Saemangeum project walked along the different pathway from the Sihwa case. The area should be managed in sustainable manners to appropriately consider conservation and development for the prosperity of local residents and future generations.

• Proceedings of the Korea Water Resources Association Conference
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• 2008.05a
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• pp.694-698
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• 2008

In hydrology, it is a difficult task to deal with multivariate time series such as modeling streamflows of an entire complex river system. Normal distribution based model such as MARMA (Multivariate Autorgressive Moving average) has been a major approach for modeling the multivariate time series. There are some limitations for the normal based models. One of them might be the unfavorable data-transformation forcing that the data follow the normal distribution. Furthermore, the high dimension multivariate model requires the very large parameter matrix. As an alternative, one might be decomposing the multivariate data into independent components and modeling it individually. In 1985, Lins used Principal Component Analysis (PCA). The five scores, the decomposed data from the original data, were taken and were formulated individually. The one of the five scores were modeled with AR-2 while the others are modeled with AR-1 model. From the time series analysis using the scores of the five components, he noted "principal component time series might provide a relatively simple and meaningful alternative to conventional large MARMA models". This study is inspired from the researcher's quote to develop a multivariate simulation model. The multivariate simulation model is suggested here using Principal Component Analysis (PCA) and Independent Component Analysis (ICA). Three modeling step is applied for simulation. (1) PCA is used to decompose the correlated multivariate data into the uncorrelated data while ICA decomposes the data into independent components. Here, the autocorrelation structure of the decomposed data is still dominant, which is inherited from the data of the original domain. (2) Each component is resampled by block bootstrapping or K-nearest neighbor. (3) The resampled components bring back to original domain. From using the suggested approach one might expect that a) the simulated data are different with the historical data, b) no data transformation is required (in case of ICA), c) a complex system can be decomposed into independent component and modeled individually. The model with PCA and ICA are compared with the various statistics such as the basic statistics (mean, standard deviation, skewness, autocorrelation), and reservoir-related statistics, kernel density estimate.