• Journal of Biomedical Engineering Research
• /
• v.30 no.5
• /
• pp.355-361
• /
• 2009

Mitochondria play a key role in maintaining life by producing ATP and heat. Recent researches have demonstrated that degenerative diseases such as heart failure, obesity/diabetes, cardiovascular disease, and psychiatric diseases are accompanied by mitochondria dysfunction. In this sense, mitochondria medicine considers the significance of mitochondria in human pathology and tries to explain degenerative diseases as a fatal consequence of mitochondria dysfunction. Here, I introduce the fundamentals of mitochondria physiology and present examples showing the relationship between mitochondria dysfunction and chronic complex diseases. Although mitochondria medicine uses a molecular biological approach predominantly, a biomedical engineering approach might play a critical role in unveiling the complexity of mitochondria medicine and in its application to the diagnosis and treatment of chronic diseases. Thus, I also briefly review the prospects of research using biomedical engineering methods.

• Korean Journal of Psychosomatic Medicine
• /
• v.1 no.1
• /
• pp.101-108
• /
• 1993

A case of a 38 year-old woman with histrionic personality who had chronic epigastric pain, dyspepsia and alternating bowel habit for more than 10 years was presented in detail on its course of two times of admission and follow-up. The diagnosis was thought as psychophy-siological disorder or gastrointestinal motility disorder of undefined etiology rather than hypo-chondriasis or Briquet's syndrome. She was characterized by sustained illness behavior and combined several physical illnesses. i.e. tuberculosis. anemia and hepatic stone. These physical diseases led to a blurring of psychological and physical boundaries regarding symptom formation. The points on consultation from medical part to psychiatric department were discussed and the supposed causal mechanisms in non-organic functional gastrointestinal disturbances were also reviewed. Physical and psychological modalities for the treatment and the abnormal illness behavior were mainly emphasized in this case.

• Proceedings of the KOSOMBE Conference
• /
• v.1997 no.05
• /
• pp.199-202
• /
• 1997

We are developing computer integrated polysomnography system. This system integrates conventional polysomnography with computer for data management, automatic analysis, scoring, and data transmission. In the first stage, we have developed the signal interface and user interface for the manual scoring and data management. For the automatic scoring of sleep stage, we have developed the protocol and have applied the analytic method in its primitive form. In the second stage we will develope a partially automatic scoring system, and finalize the fully automatic system in the final third stage.

• Korean Journal of Biological Psychiatry
• /
• v.20 no.3
• /
• pp.63-65
• /
• 2013

The new edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) is published by the American Psychiatric Association. The diagnostic systems for mental disorders have come under criticism for relying on presenting signs and symptoms with the result that they do not adequately reflect relevant neurobiological and behavioral systems. Finally, the National Institute of Mental Health (NIMH) in the United States has suggested the Research Domain Criteria (RDoC) to develop a research classification system based upon dimensions of neurobiology and behavioral aspect. The present review introduces the RDoC as a new reaseach framework.

• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
• /
• v.17 no.2
• /
• pp.103-106
• /
• 2006

Listeners' perception toward stuttering has been considered an important factor to the diagnosis and treatment of stuttering. This study intended to examine perceptual differences between speech language pathologists and laypeople toward children and adults with stuttering. A Total of 102 subjects were surveyed. speech language pathologists' perception was more stereotypical than that of laypeople. laypeople perceived adults and children with no significant differences but, clinicians viewed adults more stereotypically. speech language pathologists were not influenced by experiencer, but experienced laypeople perceived children more negatively although people who have stuttering family members showed a less stereotypically. item analysis revealed that both groups showed different perspectives between adults and children with stuttering.

• Sleep Medicine and Psychophysiology
• /
• v.18 no.1
• /
• pp.5-9
• /
• 2011

Sleep-related eating disorder (SRED) is a newly recognized parasomnia that describes a clinical condition of compulsive eating under an altered level of consciousness during sleep. Recently, it is increasingly recognized in clinical practice. The exact etiology of SRED is unclear, but it is assumed that SRED might share features of both sleepwalking and eating disorder. There have been also accumulating reports of SRED related to the administration of various psychotropic drugs, such as zolpidem, triazolam, olanzapine, and combinations of psychotropics. Especially, zolpidem in patients with underlying sleep disorders that cause frequent arousals, may cause or augment sleep related eating behavior. A thorough sleep history is essential to recognition and diagnosis of SRED. The timing, frequency, and description of food ingested during eating episodes should be elicited, and a history of concurrent psychiatric, medical, sleep disorders must also be sought and evaluated. Interestingly, dopaminergic agents as monotherapy were effective in some trials. Success with combinations of dopaminergic and opioid drugs, with the addition of sedatives, has also been reported in some case reports.

• Smart Media Journal
• /
• v.9 no.3
• /
• pp.9-17
• /
• 2020

Hippocampus is a complex brain structure embedded deep into the temporal lobe. Studies have shown that this structure gets affected by neurological and psychiatric disorders and it is a significant landmark for diagnosing neurodegenerative diseases. Hippocampus features play very significant roles in region-of-interest based analysis for disease diagnosis and prognosis. In this study, we have attempted to learn the embeddings of this important biomarker. As conventional metric learning methods for feature embedding is known to lacking in capturing semantic similarity among the data under study, we have trained deep Siamese convolutional neural network for learning metric of the hippocampus. We have exploited Gwangju Alzheimer's and Related Dementia cohort data set in our study. The input to the network was pairs of three-view patches (TVPs) of size 32 × 32 × 3. The positive samples were taken from the vicinity of a specified landmark for the hippocampus and negative samples were taken from random locations of the brain excluding hippocampi regions. We have achieved 98.72% accuracy in verifying hippocampus TVPs.

• Korean Journal of Psychosomatic Medicine
• /
• v.3 no.2
• /
• pp.214-221
• /
• 1995

There appears to be an increased incidence of anxiety symptoms in association with certain medical illness. It is usually assumed that certain medical disorders are directly associated with anxiety symptoms in that the pathophysilolgy of the medical illness somehow causes the anxiety symptoms. However, the pathophysilolgies of many such medical illnesses as well as anxiety are not known and no discrete group of medical illnesses is clearly more likely to produce anxiety symptoms than any other Moreover, anxiety symptoms may be the representation of other psychiatric symptoms, like depression and delirium. Though it is important to differentiate primary and other causes(secondary) of anxiety clinically, the clear differentiation is somewhat arbitrary, as the confusion of mind-body dichotomy. for the purpose of accurate treatment of anxiety symptoms relating medical illness, this review article focuses on those clinical features and mechanisms of anxiety that are potentially useful in differential diagnosis.

• International Journal of Advanced Culture Technology
• /
• v.11 no.1
• /
• pp.332-336
• /
• 2023

In this paper, we design and implement an ADHD diagnostic rating scale algorithm and virtual reality- based digital treatment by combining virtual reality technology that enables multiple access based on specialized medical data. The VR ADHD digital treatment to be implemented is intended to be applied directly to diagnosis and treatment of child/adolescent ADHD by applying various psychiatric treatment technologies. In order to evaluate the usability of the digital therapeutic agent developed in this paper, an expert group consisting of 2 males and 12 females "targeted counseling psychology majors at the Asian Dementia Center once a day for 3 weeks, ADHD VR-based digital therapeutics for children Experienced and usability evaluation conducted. As a final result of this thesis, it was possible to develop attentional concentration ability, working memory improvement ability, and impulsive control ability in four games of digital therapy, and it was possible to confirm significant results that can be expected to have ADHD therapeutic effects.

• Korean Journal of Psychosomatic Medicine
• /
• v.10 no.2
• /
• pp.166-175
• /
• 2002

Recently many researches support the use of traditional psychiatric treatments in the management of chronic pain. Chronic pain is a significant public health problem and frustrating to everyone affected by it. Psychiatrists offer skills with treatments now recognized as effective in the management of chronic pain. In addition to the diagnosis and treatment of psychiatric co-morbidity, the application of psychological treatments to chronic pain, and the development of interdisciplinary efforts to provide comprehensive health care to the patient disabled with chronic pain, psychiatrists have particular skill in pharmacological treatment that have proven efficacy for a variety of chronic pain conditions. With their expertise in the use of psychoactive medication plus their interest in the personal and family dynamics of patients, psychiatrists have the capacity to be involved in the treatment of patients with chronic pain. So, the author reported three cases of patient with pain disorder associated with psychological factors, and reviewed to propose that psychiatrists in Korea should take an active role in the care of these patients.