• 대한약학회:학술대회논문집
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• 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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• pp.378.3-379
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• 2002

Prunus serrulata var. spontanea(Rosaceae) is a large sized tree widely distributed throughout Korea. The red fruits are edible and are used in traditional folk medicine against heart failure from beriberi. dropsy. mastitis, an emmenagogue, and toothache. Also. the bark of P. serrulata var. spontanea has been used for detoxification. and relaxation and as an antitussive in traditional Korea medicine. (omitted)

• 한국환경복원기술학회지
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• 제14권6호
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• pp.17-27
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• 2011

Prunus serrulata var. serrulata f. spontanea (E. H. Wilson) C. S. Chang was treated with dried swine excrement at various concentration levels, and their growth reactions and the contents of total kjeldahl nitrogen and total phosphoric acid were analyzed. The result is as follows; 1. When the plants were treated with 0.25% of dried swine excrement, the seed germination rate of Prunus serrulata var. serrulata f. spontanea was higher than that of the control. However, it showed a tendency to decrease when the treatment concentration got higher than 0.25%. 2. The growth rate of species was highest when they were treated with 0.25% of dried swine excrement. It tended to decrease with higher treatment concentration than 0.25%. Significant difference was clear between the control and the experimental plants of Prunus serrulata var. serrulata f. spontanea. 3. The contents of nitrogen and phosphoric acid in Prunus serrulata var. serrulata f. spontanea also got higher as the concentration of dried swine excrement increased. However, the content of total kjeldahl nitrogen was highest in the leaves, and followed by the roots and stems. In contrast, the content of total phosphoric acid were highest in the roots, and followed by the leaves and stems. Therefore, stems had the lowest contents of both nitrogen and phosphoric acid. 4. The contents of total kjeldahl nitrogen and total phosphoric acid in the soil were measured before and after the growth experiment of Prunus serrulata var. serrulata f. spontanea treated with dried swine excrement. The contents of nitrogen and phosphoric acid significantly decreased after the experiment. In conclusion, the contents of total kjeldahl nitrogen and total phosphoric acid accumulated in the plants increased as the concentration level of dried swine excrement got higher. The seed germination and plant growth rates were best at 0.25% treatment of dried swine excrement. The treatment of dried swine excrement may bring high effects on increasing the plant growth rate but could damage the plants with higher concentration than they need. Different optimal concentration levels of dried swine excrement for different plants should be found before it is used as fertilizer.

• Archives of Pharmacal Research
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• 제28권10호
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• pp.1127-1130
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• 2005

A new phenolic glucoside (1), pursargentoside, was isolated from the leaves of Prunus serrulata var. spontanea, along with three other known compounds, orobol 7-O-glucoside (2), $1{\beta}$, $2{\alpha}$, $3{\alpha}$, 24-tetrahydroxy-urs-12-en-28-oic acid (3), and chlorogenic acid (4). The structure of pursargentoside (1) was identified by spectroscopic data analysis including 1D and 2D NMR spectroscopy, as 2-O-${\beta}$-(6'-benzoyl)-glucopyranosyl o-(Z)-coumaric acid. Compounds 1, 2, and 4 exhibited ONOO- scavenging activity, whereas compound 3 was determined to be virtually inactive.

• Archives of Pharmacal Research
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• 제25권6호
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• pp.865-872
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• 2002

In the course of the investigations of natural antioxidants, we examined the antioxidant activities of the methanol (MeOH) extracts of some selected Prunus species, including P. buergeriana, P. davidiana, P padus, P. pendula for. ascendens, P. sargentii, P. serrulata var. spontanea and P. yedoensis by three methods as represented by the 1, 1-diphenyl-2-picrylhydrazyl (DPPH) radical, total ROS (reactive oxygen species) and the peroxynitrite ($ONOO^-$) scavenging activity tests. We also evaluated the activities of the organic solvent-soluble fractions, including the dichloromethane ($CH_2Cl_2$), ethyl acetate (EtOAc), n-butanol (n-BuOH) fractions and the water ($H_2O$) layer of P. serrulata var. spontanea leaves. By means of bioassay-directed fractionation, we isolated eleven known flavonoids (1-11) from the EtOAc soluble fraction of the MeOH extract of the Prunus serrulata var. spontanea leaves, exhibiting strong antioxidant activity and characterized as prunetin (1), genistein (2), quercetin (3), prunetin $4'-O-{\beta}-glucopyranoside$ (4), kaempferol $3-O-{\alpha}-arabinofuranoside$ (5), prunetin $5-O-{\beta}-glucopyranoside$ (6), kaempferol $3-O-{\beta}-xylopyranoside$ (7), genistin (8), kaempferol $3-O-{\beta}-glucopyranoside$ (9), quercetin $3-O-{\beta}-glucopyranoside$ (10) and kaempferol $3-O-{\beta}-xylopyranosyl-(1{\rightarrow}2)-{\beta}-glucopyranoside$ (11). Compounds 3 and 10 showed good activities in all tested model systems. Compounds 2 and 8 showed scavenging activities in the DPPH and $ONOO^-$ tests, while compounds 5, 7, 9 and 11 were active in the $ONOO^-$ and ROS tests. On the other hand, compounds 1, 4 and 6 did not show any activities in the tested model systems.

• 한국식품영양과학회지
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• 제38권6호
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• pp.750-756
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• 2009

기능성 소재로서의 버찌분말의 이용가능성을 알아보기 위해 버찌분말을 0, 3, 5, 7 및 10% 첨가한 머핀을 제조하여 품질특성을 조사하였다. 머핀의 물성은 버찌분말의 첨가에 따라 경도(hardness)는 증가하였고 검성(gumminess) 및 씹힘성(chewiness)은 감소하였다. 색도는 첨가량이 증가할수록 빵껍질(crust)과 빵속(crumb)에서 명도와 황색도가 감소하고 적색도는 증가하였다. 또한 버찌 분말의 농도가 증가함에 따라 항산화 활성이 증가하였다. 관능검사 결과 버찌분말첨가 머핀에서 색, 향, 맛, 부드러움, 촉촉함, 전체적인 기호도면에서 무첨가구에 비해 전반적으로 높게 평가되었으며, 전체적인 기호도는 5% 첨가구에서 가장 높은 점수를 나타내었다. 이러한 결과로 볼 때 머핀의 품질 및 관능 특성, 기능성을 고려한 버찌분말 첨가량은 5% 첨가구가 최적 조건일것으로 판단되었다.

• 한국식품영양학회지
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• 제36권3호
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• pp.172-184
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• 2023

The objective of this study was to determine the efficacy of a natural product of cherry tree (Prunus serrulata var. spontanea: PS) as a test substance for improving cytokine and ovalbumin-specific IgE using an ovalbumin-induced asthma disease model of 5-week-old male BALB/c mice. Lung tissue pathology was analyzed to confirm anti-inflammatory and asthmatic effects. As a result of examining the effect on changes in inflammatory cells in bronchoalveolar lavage fluid in an ovalbumin-induced asthma disease model by administering the PS sample, total cells, eosinophil, neutrophil, lymphocyte, and monocytes were significantly decreased. Concentrations of cytokine-based TNF-alpha and IL-4 and immunoglobulin E in serum were significantly increased in the asthma-inducing negative control group than in the normal group. However, high concentrations of PS decreased them. In histopathological examination of the lung tissue, it was confirmed that inflammatory cells infiltrated around the alveoli and bronchioles were increased in ovalbumin-induced asthma disease model. After administration of cherry tree extract, bronchiolar morphological changes such as mucosal thickening were slightly improved. From the above results, it was confirmed that extract of cherry tree significantly reduced inflammation expression and tissue damage in alveolar tissues. It was also confirmed that the cherry tree extract had an excellent efficacy in improving asthma inflammation.

• Applied Biological Chemistry
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• 제42권2호
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• pp.134-139
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• 1999

새로운 식용 적색색소자원을 개발하기 위하여 버찌의 anthocyanin색소를 ethanol 추출하여 광선, 온도, 유기산, 금속이온 및 pH에 의한 영향을 검토하였다. 본 색소는 광선에 안정하여 20일 까지도 69%의 색소잔존율을 나타내었고 광선 차단용 포장재를 사용 시 상당한 색소잔존효과를 나타내었다. 본 색소는 열에 대단히 안정하여 $115^{\circ}C$에서 30분까지 64%의 색소잔존율을 나타내었다. $25^{\circ}C$의 암소조건에서 첨가된 유기산에 의해서는 색소의 농색화효과가 높게 나타났으며, $25^{\circ}C$의 암소조건에서 첨가된 금속이온에 의해서는 $Na^+,\;K^+,\;Mg^{2+},\;Ca^{2+}$ 및 $Mn^{2+}$에 의해서는 20일까지 안정하였고, $Cu^{2+}$와 $Fe^{3+}$에 의해서는 심각한 안정성 저해를 나타냈으며, $Al^{3+}$에 의해서는 자색으로 전환되었다. pH가 낮을수록 색소의 농색화효과가 높았다. 이로 미루어 본 색소는 대단히 우수한 식용 적색색소자원임을 알 수 있었다.

• 대한약학회:학술대회논문집
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• 대한약학회 2001년도 Proceedings of International Convention of the Pharmaceutical Society of Korea
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• pp.260.2-260.2
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• 2001

• 한국식품영양과학회지
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• 제38권7호
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• pp.926-934
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• 2009

버찌분말을 첨가한 파운드케이크(0, 5, 10, 15%)를 $25^{\circ}C$에 저장하면서 10일간 품질특성을 알아보았다. 반죽의 pH는 버찌분말 첨가에 의해 감소하였으며, 파운드케이크의 굽기 손실률은 1$11.47{\sim}12.67%$로 버찌분말 첨가에 따라 증가하는 경향을 보였으나 유의적인 차이는 보이지 않았고, 높이와 비용적은 버찌분말 첨가에 따라 감소하였다. 색도는 crumb의 적색도를 제외하고, 버찌분말 첨가에 따라 crust와 crumb 모두 명도, 적색도, 황색도가 유의적으로 감소하였다. 조직감은 버찌분말 첨가에 따른 유의차는 보이지 않았으나 버찌분말 첨가에 의해 경도는 증가하는 경향을, 부착성 및 탄력성은 감소하는 경향을 나타내었다. 노화도는 무첨가구에 비해 버찌분말 첨가구에서 노화도가 높았으나 유의차는 없었다. 항산화 활성은 10% 및 15% 버찌분말 첨가구에서 높은 활성을 보였으며 관능검사 결과 색에 대한 선호도를 제외하고 10% 및 15% 첨가구에서 높은 평가를 나타내었다. 따라서 저장 동안의 품질 및 관능 특성, 기능성을 고려한 버찌분말 첨가량은 10% 첨가구가 최적 조건일 것으로 판단되었다.

• 한국식품영양과학회지
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• 제38권7호
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• pp.920-925
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• 2009

기능성 소재로서의 버찌분말의 이용가능성을 알아보기 위해 버찌분말을 0, 3, 6 및 9% 첨가한 쿠키를 제조하여 품질 특성을 조사하였다. 쿠키 반죽의 pH는 버찌분말 첨가에 의해 감소하였으며, 밀도는 증가하였다. 쿠키의 퍼짐성은 버찌분말 첨가에 의해 감소하였으며, 쿠키의 색은 L(lightness), b(yellow ness)값이 감소하고, a(redness)값이 증가하는 것으로 나타났다. 쿠키의 경도는 버찌분말 첨가량이 증가할수록 감소하였으며, 항산화 활성은 버찌분말 첨가량이 증가함에 따라 항산화활성이 증가하였다. 쿠키의 관능검사 결과 버찌분말 첨가는 색, 냄새, 맛, 질감 및 전체적인 기호도를 향상시키는 긍정적인 영향을 미치나 9% 이상의 너무 많은 버찌분말 첨가는 관능적인 기호도를 오히려 떨어뜨리는 것으로 나타났으며, 버찌분말 6% 첨가군의 선호도가 가장 좋아 쿠키의 품질 및 관능 특성, 기능성을 고려한 버찌분말첨가량은 6% 첨가구가 최적 조건일 것으로 판단되었다.