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A Phenolic Glucoside Isolated from Prunus serrulata var. spontanea and its Peroxynitrite Scavenging Activity  

Jung Hyun Ah (Faculty of Food Science and Biotechnology, Pukyong National University)
Chung Hae Young (College of Pharmacy, Pusan National University)
Kang Sam Sik (Natural Product Research Institute and College of Pharmacy, Seoul National University)
Hyun Sook Kyung (Faculty of Food Science and Biotechnology, Pukyong National University)
Kang Hye Sook (Faculty of Food Science and Biotechnology, Pukyong National University)
Choi Jae Sue (Faculty of Food Science and Biotechnology, Pukyong National University)
Publication Information
Archives of Pharmacal Research / v.28, no.10, 2005 , pp. 1127-1130 More about this Journal
Abstract
A new phenolic glucoside (1), pursargentoside, was isolated from the leaves of Prunus serrulata var. spontanea, along with three other known compounds, orobol 7-O-glucoside (2), $1{\beta}$, $2{\alpha}$, $3{\alpha}$, 24-tetrahydroxy-urs-12-en-28-oic acid (3), and chlorogenic acid (4). The structure of pursargentoside (1) was identified by spectroscopic data analysis including 1D and 2D NMR spectroscopy, as 2-O-${\beta}$-(6'-benzoyl)-glucopyranosyl o-(Z)-coumaric acid. Compounds 1, 2, and 4 exhibited ONOO- scavenging activity, whereas compound 3 was determined to be virtually inactive.
Keywords
Prunus serrulata var.; spontanea; Rosaceae; Phenolic glucoside; Pursargento-side; Peroxynitrite scavenging activity;
Citations & Related Records
Times Cited By KSCI : 1  (Citation Analysis)
Times Cited By Web Of Science : 4  (Related Records In Web of Science)
Times Cited By SCOPUS : 3
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