• Advances in materials Research
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• v.8 no.1
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• pp.11-24
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• 2019

This paper presents a review study for energy-efficient gas turbines (GTs) with cycles which contributes significantly towards sustainable usage. Nonetheless, these progressive engines, operative at turbine inlet temperatures as high as $1600^{\circ}C$, require the employment of highly creep resistant materials for use in hotter section components of gas turbines like combustion chamber and blades. However, the gas turbine obtain its driving power by utilizing the energy of treated gases and air which is at piercing temperature and pushing by expanding through the several rings of steady and vibratory blades. Since the turbine blades works at very high temperature and pressure, high stress concentration are observed on the blades. With the increasing demand of service, to provide adequate efficiency and power within the optimized level, turbine blades are to be made of those materials which can withstand high thermal and working load condition for longer cycle time. This paper depicts the recent developments in the field of implementing the best suited materials for the GTs, selection of proper Thermal Barrier Coating (TBC), fracture analysis and experiments on failed or used turbine blades and several other designing and operating factors which are effecting the blade life and efficiency. It is revealed that Nickel based Superalloys were promising, Cast Iron with Zirconium and Pt-Al coatings are used as best TBC material, material defects are the foremost and prominent reason for blade failure.

• Journal of Korean Neurosurgical Society
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• v.66 no.2
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• pp.121-132
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• 2023

Objective : The parafascicular nucleus (PF) plays important roles in controlling the basal ganglia. It is not well known whether the PF affects the development of abnormal involuntary movements (AIMs). This study was aimed to find a role of the PF in development of AIMs using optogenetic methods in an animal model. Methods : Fourteen rats were underwent stereotactic operation, in which they were injected with an adeno-associated virus with channelrhodopsin (AAV2-hSyn-ChR2-mCherry) to the lateral one third of the PF. Behavior test was performed with and without optical stimulation 14 days after the injection of the virus. AIM of rat was examined using AIM score. After the behavior test, rat's brain was carefully extracted and the section was examined using a fluorescence microscope to confirm transfection of the PF. Results : Of the 14 rats, seven rats displayed evident involuntary abnormal movements. AIM scores were increased significantly after the stimulation compared to those at baseline. In rats with AIMs, mCherry expression was prominent in the PF, while the rats without AIM lacked with the mCherry expression. Conclusion : AIMs could be reversibly induced by stimulating the PF through an optogenetic method.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.26 no.1
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• pp.24-39
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• 2000

Various methods and graft materials have been used to fill in the defect adjacent to the implants and considered as clinically acceptable. But it is not clear whether the regenerated bone increases the implant-bone contact and supports the implant. The purpose of this study is to evaluate regenerated bone surrounding implants using bone morphogenetic protein(BMP) and demineralized freeze-dried bone(DFDB), and the interfaces between implants and regenerated bone. bBMP was extracted and partially purified from the bovine bone matrix using heparine chromatography. Demineralized freeze-dried bone was made from the dog. Inactive insoluble collagenous bone matrix(IBM) of dog was used as carrier of bBMP. Interfaces of titanium coated epoxy resin implants were processed for demineralized section for transmission electron microscopy(TEM) and those of screw type implants were for nondemineralized section for light and fluoromicroscopic examination. Implants were inserted in the inferior border of mandible of adult dogs and artificial bony defects($3{\times}3{\times}4mm$) were made at the mesial and distal side of implants. Defects were filled with BMP(BMP group) and DFDB(DFDB group). For the fluoromicroscopic examination, the fluorescent dyes(oxytetracycline, calcein green, alizarin red) were injected 2, 4, 6, 8, 12 weeks after implantation. The experimental animals were sacrificed at the 6th and the 12th week and their mandible were extirpated and processed for examination with light microscopy, fluoromicroscopy and TEM. The obtained results were as follows : 1. By the light microscopic findings, the defects were filled with woven bone at the 6th week and compact bone at the 12th week, and the osseointegrations were seen in both groups. There was no histological difference between them. 2. On the basis of the histomorphometric analysis, BMP group(6th week: 40.25%, 12th week: 56.04%) had higher bony contact ratio than DFDB group(38.37%, 42.63%). There was significant difference between two groups at the 12th week(p<0.05). 3. The amount of bone formation in BMP group was more prominent than in DFDB group. Significant difference was noted among two groups at the 6th and the 8th week(p<0.05). 4. By the transmission electron microscopic findings, $0.4-2{\mu}m$ soft tissue layer was found in adjacent to the interfaces and over the collagen fibrils of bone at the 6th week. However, about 100nm amorphous layer was noted at the interface or collagen fibrils directly extended to the titanium surface at the 12th week. There was no significant difference between two groups. 5. These results suggest that BMP and DFDB can be used as good graft materials in the regeneration of bone adjacent to implant, and BMP is more valuable as a bone inducer than DFDB.

• Journal of Periodontal and Implant Science
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• v.45 no.3
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• pp.120-126
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• 2015

Purpose: With the significance of stable adhesion of alveolar bone and peri-implant soft tissue on the surface of titanium for successful dental implantation procedure, the purpose of this study was to apply microgrooves on the titanium surface and investigate their effects on peri-implant cells and tissues. Methods: Three types of commercially pure titanium discs were prepared; machined-surface discs (A), sandblasted, large-grit, acid-etched (SLA)-treated discs (B), SLA and microgroove-formed discs (C). After surface topography of the discs was examined by confocal laser scanning electron microscopy, water contact angle and surface energy were measured. Human gingival fibroblasts (hGFs) and murine osteoblastic cells (MC3T3-E1) were seeded onto the titanium discs for immunofluorescence assay of adhesion proteins. Commercially pure titanium implants with microgrooves on the coronal microthreads design were inserted into the edentulous mandible of beagle dogs. After 2 weeks and 6 weeks of implant insertion, the animal subjects were euthanized to confirm peri-implant tissue healing pattern in histologic specimens. Results: Group C presented the lowest water contact angle ($62.89{\pm}5.66{\theta}$), highest surface energy ($45{\pm}1.2mN/m$), and highest surface roughness ($Ra=22.351{\pm}2.766{\mu}m$). The expression of adhesion molecules of hGFs and MC3T30E1 cells was prominent in group C. Titanium implants with microgrooves on the coronal portion showed firm adhesion to peri-implant soft tissue. Conclusions: Microgrooves on the titanium surface promoted the adhesion of gingival fibroblasts and osteoblastic cells, as well as favorable peri-implant soft tissue sealing.

• Korean Institute of Interior Design Journal
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• v.19 no.4
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• pp.11-21
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• 2010

The purpose of this study is to examine the design characteristic of the facade of the main adminstration building in university. The main administration building which is a basic of educational facilities has various administration setups, such as the register's office, the student affairs section, the planing department, the general affair's office and so on. This building performs academic, administration, facilities management, and admissions service. Also, the building has an ideological, historical, and symbolic image, having an organic relationships with the other educational facilities. This study choose one hundred seven universities, except universities that does not provide information easily and the second campus which does not have the main administration building, as the subjects of the study. The analysis is derived from the design elements applied to facade design of the main administration building and this is divided into design principles(balance symmetry, contrast, rhythm), the formal composition(geometrical, linear), and the style of architecture(classical architecture and modern architecture). The results of the research are summarized as follows: The design characteristic of the facade of the main adminstration building in university has chronologically changed. First of all, in the 1940's, symmetry emphasized on the center of building, superimposition, division, pediment, and arch were marked. Then, superimposition was prominent in the 1950's and symmetry emphasized on the center of building was shown in the 1960s again. Flat roof was in the 1970's, 1990s and 2000's. Finally, pediment was dominant in the 1980's. The design elements of the main administration building can be samples of chronological styles of architecture. Facade design, with proper design of the past and recent times, includes the meaning that achieve the great purpose of the university by emphasizing visual images.

• The Korean Journal of Cytopathology
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• v.7 no.1
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• pp.69-74
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• 1996

Malignant rhabdold tumor is a distinct renal tumor in the pediatric age group. It was originally described as a rhabdomyosarcomatold variant of Wilms' tumor. However, subsequent studies fatted to confirm myogenous differentiation, so it is now considered to be a distinct and unique type of highly malignant tumor, histogenetically unrelated. Although extrarenal forms of this tumor are rare, several examples have been described in other sites, especially the liver, prostate, paravertebral area, urinary bladder and soft tissue. We experienced a case of malignant rhabdiod tumor located in the intraabdominal cavity in a 10 month-old boy. Smear of peritoneal fluid showed round, polygonal and irregular shaped cells with large nuclei, ample cytoplasm containing light pink to purple cytoplasmic inclusions, and one or a few prominent nucleoli. Immunocytochemistry revealed positivity to cytokeratin, epithelial membrane antigen and vimentin, and negativity to desmin and neuron-specific enolase. These distinct cytologic appearance and immunophenotypes were most consistent with a diagnosis of extrarenal malignant rhabdoid tumor. The cytoplasmic inclusions were correlated with eosinophilic inclusions seen in histologic section and electron microscopy confirmed this interpretation, showing filamentous aggregations in the cytoplasms of the tumor cells.

• Advances in pediatric surgery
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• v.1 no.1
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• pp.68-72
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• 1995

Segmental dilatation of the colon is a very rare disease entity of unknown etiology and may mimic Hirschsprung's disease. It is characterized by dilatation of a segment of the colon of variable length with obstruction due to lack of peristalsis in a normally innervated intestine. Recently authors experienced a case of segmental dilatation of the sigmoid colon in a 6 month-old male, who presented with severe constipation, abdominal distention, and abdominal mass since 2 months of age. Down's syndrome and congenital nystagmus were associated. Barium enema demonstrated focal dilatation of the sigmoid colon, but the rectum and descending colon proximal t o the affected colon were of normal caliber. Rectal suction biopsy with acetylcholinesterase staining was normal and anorectal manometry showed normal rectosphincteric reflex. At operation, there was a massively dilated and hypertrophied sigmoid colon with increased tortuous serosal vessels, measuring 15 cm in length and 10 cm in width. Teniae coli were identifiable in the affected segment. Frozen section biopsies at the proximal, affected, and distal colon showed ganglion cells. Descending loop colostomy was constructed initially and segmental resection and end to end colocolostomy were carried out 3 months later. Final histologic examination showed 1) normal colonic mucosa with ganglion cells, 2) prominent submucosal fibrosis and marked muscular hypertrophy, 3) unremarkable acetylcholinesterase activity and immunohistochemical findings against S-100 protein. On 8 months follow-up, he has been doing well and moves bowels 1-2 times daily.

• The Korean Journal of Petroleum Geology
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• v.6 no.1_2 s.7
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• pp.1-7
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• 1998

A multichannel seismic profile from the southwestern margin of the Ulleung Basin, East Sea, was analysed in detail to interpret the middle to late Miocene sequence stratigraphic evolution of the area. A regressive package is overlying a transgressive package which, in turn, is underlain by older uplifted and deformed sedimentary layers. A prominent condensed section separates the regressive and transgressive packages. The transgressive package is characterized by onlapping onto the underlying uplifted and deformed strata. The regressive package contains six prograding sequences composed of seismically resolvable lowstand, highstand, and transgressive systems tracts. Most of the depositional sequences comprise lowstand systems tracts consisting of basin-floor fan, slope fan, and prograding complex. Potential reservoirs in the regressive package are turbidite sands in basin-floor fans, channel-fill sands and overbank sand sheets in slope fans, and incised valley-fill sands in the shelf. The shallow marine sands in transgressive packages are another type of reservoir. Detailed sequence stratigraphic analysis, seismic data reprocessing, and 3-D seismic survey are suggested for the successful hydrocarbon exploration in the study area.

• Structural Engineering and Mechanics
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• v.60 no.4
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• pp.633-653
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• 2016

One of the major threats to the stability of classical columns and colonnades are earthquakes. The behavior of columns under high seismic excitation loads is non-linear and complex since rocking, wobbling and sliding failure modes can occur. Therefore, three dimensional simulation approaches are essential to investigate the in-plane and out-of-plane response of such structures during harmonic and seismic loading excitations. Using a software based on the Distinct Element Method (DEM) of analysis, a three dimensional numerical study has been performed to investigate the parameters affecting the seismic behaviour of colonnades' structural systems. A typical section of the two-storey colonnade of the Forum in Pompeii has been modelled and studied parametrically, in order to identify the main factors affecting the stability and to improve our understanding of the earthquake behaviour of such structures. The model is then used to compare the results between 2D and 3D simulations emphasizing the different response for the selected earthquake records. From the results analysis, it was found that the high-frequency motion requires large base acceleration amplitude to lead to the collapse of the colonnade in a shear-slip mode between the drums. However, low-frequency harmonic excitations are more prominent to cause structural collapse of the two-storey colonnade than the high-frequency ones with predominant rocking failure mode. Finally, the 2D analysis found to be unconservative since underestimates the displacement demands of the colonnade system when compared with the 3D analysis.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.30 no.5
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• pp.381-387
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• 2017

Fiber-reinforced composites not only have a direction of thermal expansion coefficient, but also inevitably suffer thermal stress effects due to the difference between the manufacturing process temperature and the actual use temperature. The damage caused by thermal stress is more prominent in the case of thick composite laminates, which are increasingly applied in the aerospace industry, and have a great influence on the mechanical function and fracture strength of the laminates. In this study, the dimensional reduction and thermal stress recovery theory of composite beam structure having high slenderness ratio is introduced and show the efficiency and accuracy of the thermal stress comparison results between the 3-D finite element model and the dimension reduction beam model. Efficient recovery analysis study will be introduced by reconstructing the thermal stress of the composite beam section applied to the thermal environment by constructing the dimensional reduction modeling and recovery relations.