• E2M - 전기 전자와 첨단 소재
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• 제6권1호
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• pp.63-68
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• 1993

CO$_{2}$기체의 운동량변환, 진동여기, 전자여기 및 전리충돌 단면적의 결정은 온도 293[.deg.K], 상대전계의 세기 E/N은 1.0[Td].leq.E/N.leq.200[Td]의 범위에서 볼츠만 방정식을 Backward-Prolongation 방법으로 해석하여 전자 이동속도의 계산값을 산출하고 이것을 M. T. Elford에 의해 실험적으로 측정된 이동속도의 값과 비교하였다. 본 연구에서 운동량변환충돌단면적은 Hake & Phelps의 값을 기초로 하였으며 온도 293[.deg.K], 상대전계의 세기 E/N은 3.0[Td].leq.E/N.leq.50[Td]인 범위 전자에너지분포함수 및 전자특성에너지는 상대전계의 세기 E/N이 1.0[Td].leq.E/N.leq.200[Td]인 범위에서 산출하였다.

• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 2003년도 Annual Meeting of KSAP : International Symposium on Pharmaceutical and Biomedical Sciences on Obesity
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• pp.71-71
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• 2003

Methanol extract of Loranthus yadoriki showed the prolongation effect of bleeding time in vivo using mice in dose dependent manner. From the MeOH extract of Loranthus yadoriki, compound-A was isolated by the activity guided isolation method using silicagel column chromatography. The anti-coagulant activity was evaluated by the bleeding time test in vivo and plasma recalcification time test in vitro. Compound A showed moderate anti -coagulant activity on plasma recalcification time in vitro.

• 생약학회지
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• 제17권1호
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• pp.91-99
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• 1986

The single treatment of mice with steam distillate, non-volatile ether extract and methanol extract from mace (Arils of Myristica fragrans) caused a significant prolongation of hexobarbital-induced narcosis and increase in strychnine toxicity as well as a significant decrease in hepatic microsomal drug metabolizing enzyme activities. On 7 consecutive daily administrations, however, the duration of hypnosis was markedly shortened and significant increases in the hepatic enzyme activities were shown. With systematic fractionation by $SiO_2$ column chromatography of non-volatile ether fraction monitoring by animal tests a new lignan (mp $70{\sim}72^{\circ}$, MW 328, $[{\alpha}]^{20}_D+5.28$) was isolated as an active principle and its structure was elucidated as (2R, 3S)-1-(3,4-methylendioxyphenyl)-2,3 dimethyl-4-(4-hydroxy-3-methoxyphenyl) butane.

• 대한음성학회지:말소리
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• 제67호
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• pp.61-77
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• 2008

The purpose of this study is to blow the characteristics of disfluency in childhood. The subjects were 144 normal children at the age of between 3 to 8 years who lived in Seoul. All the subjects provided spontaneous conversational speech samples during free-play interactions with their friends. We investigated the patterns and the frequency of disfluency and its relevance with subject's age, speaking rate and MLU(mean length of utterance). The results of this study can be summarized as follows. (1) There was no difference in the frequency of disfluency with the speaker's age or speaking rate. (2) Interjection was the most frequently occurring pattern of disfluency. (3) Prolongation, revision, interjection increased with age while part-word repetition, single-syllable word repetition, multi-syllable word repetition decreased gradually. (4) A significant effect of MLU on the frequency of disfluencies were demonstrated. The regression analysis has shown that more disfluencies occurred in utterances of children whose MLU is longer.

• 사상체질의학회지
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• 제2권1호
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• pp.177-188
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• 1990

In order to investigate experimentally the clinical effects of Soumin Kamikop'ungsan (少陰人 加味祛風散) that was prescribed to cure the Wisuhanrihanbyung (胃受寒裡寒病) of Sumin (少陰人) the author experimented various activities of mixed extract from the Sournin Kamikop'ungsan by the method prescribed in the experimental part. The results of the studies were summerized as follows: 1. Analgesic effects by acetic acid and Randall-Sellito experimental method were noted. 2. Anticonvulsive effect to strychnine was noted. 3. The sedation effects by the unbalanced effects of spontaneous momentum by wheel cage method, muscle relaxing action by Rotor rod method were noted. 4. A prolongation of anesthetic time by Thiopental-Na on the mice was noed. 5. The expansion of blood vessels by relaxation of smooth muscle was noted. According to the above results, results of Soumin Kamikop'ungsan on oriental medical references were consistent with the actual experimental results.

• 사상체질의학회지
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• 제2권1호
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• pp.135-147
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• 1990

In order to investigate experimentally the clinical effects. of $Tae{\breve{u}}min$ Chungpaesagan-Tang (太陰人 淸肺瀉肝湯) that was prescribed to cure the $Kansuy{\breve{o}}lriy{\breve{o}}lby{\breve{o}}ng$ (肝受熱裏熱病) of $Tae{\breve{u}}min$, the author experimented various activities of mixed extract from $Tae{\breve{u}}min$ Chungpaesagan-Tang by the methods prescribed in the experimental part. The results of the studies were summarized as follows; 1. In the acetic acid method experiment and the pressing hind paw method experiment, analgesic effects were noted. 2. The prolongation of the duration of hypnosis induced by Pen to barbital-sodium was noted. 3. Spontaneous movement of the isolated mice ileum was markedly suppressed. and Contraction to induced by acetylcholine, Barium chloride was Inhibited. 4. Antipyretic action by Thyphoid vaccine were noted in mice. 5. Significant anti-edemic effects were recognized on the edema induced by yeast. 6. Hypotensive action due to vaso-dilatating of normal rats and rabbits were noted.

• 사상체질의학회지
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• 제2권1호
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• pp.123-134
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• 1990

In order to investigate experimentally the clinical effects of Taeuminkalkunhaeki-tang (太陰人葛根解肌湯) that was prescribed to cure the Kansuyolriyolbyong (肝受熱裏熱病) of Taeumin, the author experimented various activities of mixed extract from Taeuminkalkunhaeki-tang by the methods prescribed in the experimental part. The results of the studies were summarized as follows: 1. Sedative effects such as malfunction of the spontaneous motor activity in the wheel cage method experiment and muscle relaxation in the rotor rod method experiment were noted. 2. In mice, the prolongation of the duration of hypnosis Induced by thiopental-Na was noted. 3. In the acetic acid method experiment and the pressing hind paw method experiment, analgesic effects were noted. 4. Inhibitory effects were noted on the convulsions incuced by strychine and picrotoxin. 5. The expansion of blood vessels by relaxation of smooth muscle was noted. According to the above results, effects based on oriental medical references approximate to the actual experimental results.

• 대한인간공학회지
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• 제11권1호
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• pp.67-79
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• 1992

Cardiac systolic time intervals (STLs) and Heather index (HI) were used to access changes in left ventricular function of six male subjects exposed to postural changes,$0^{\circ}C$, ${\pm}2^{\circ}C$, ${\pm}45^{\circ}C$, ${\pm}90^{\circ}C$, Significant prolongation of the pre-ejection period (PEP) and PEP/ LVET ratio, shortening of the left ventricular ejection time (LVET), STI, HI and $1/PEP^{2}$were observed during exposure to both $+45^{\circ}C $ and $+90^{\circ}C $But the values measured during $-45^{\circ}C $ and$-90^{\circ}C $ were reversed. Changes in fluid shift, filling volume, preload, after load and sympathetic activities may account for the observed findings. Early response of cardiac foctions was recorded using impedance cardiography. This method is very simple but accurate. Thus it will be useful in this aerospace and work physiology. In conclusion, STIs appear to provide reliable noninvasive method for examining changes of cardiac function during exposure to postural changes.

• 대한임상독성학회지
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• 제3권1호
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• pp.67-70
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• 2005

Pimozide and haloperidol are typical antipsychotics. They share a similarity in pharmacotherapeutic and adverse effect profiles. Cardiovascular effects may be seen as alterations in heart rate, blood pressure, and cardiac conduction. Conduction disturbances may occur ranging from asymptomatic prolongation of the QT interval to fatal ventricular arrhythmia. So in the case of anti psychotics overdose, the patient must be carefully monitored by continuous electrocardiography (ECG). We experienced a 34-year-old woman of schizophrenia with recurrent ventricular tachycardia after pimozide and haloperidol overdose. Initially she was slightly drowsy, however her ECG showed normal sinus rhythm. After 6 hours on emergency department entrance, her ECG monitoring showed ventricular tachycardia and we successfully defibrillated. There were five times events of ventricular arrhythmia during the in-hospital stay. She was discharged 5 days later without any other complications.

• Natural Product Sciences
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• 제4권2호
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• pp.88-90
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• 1998

An acid polysaccharide (SFP), was extracted from alga Sargassum fusiforme in hot water, was purified by ion exchange chromatography on DEAE-cellulose. The PC, chemical analysis, electrophoresis and IR of SFP indicated that it was a kind of alginate with a mol. wt. of 13,000 and a molar ratio of mannuronic acid to guluronic acid 2.75. Pharmacological tests showed that SFP could prolong the survival duration of mice suffering from ascitic Sarcoma 180 with a rate of life prolongation of 63.44%.