• Title/Summary/Keyword: Profiling analysis

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A Study on the Profiling of Collect Site for the Effective Reputation Analysis (효과적인 평판분석을 위한 수집사이트 프로파일링에 관한 연구)

  • Song, Eun-Jee;Kang, Min-Sik
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2014.05a
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    • pp.617-618
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    • 2014
  • 본 논문에서는 보다 정확하고 효과적인 평판분석을 위하여 서비스 산업별 타겟으로 하는 수집사이트를 프로파일링 하는 방법을 제안한다. 먼저 각 서비스에 특화된 타겟 사이트를 추출하고 등록하고 각 서비스에 관련한 정보 및 의견 공유 게시판과 지식인 추천/질문 등 지식 공유 사이트를 추출한다. 또한 업종별 주요 사이트를 선택하고 등록하여 유효 데이터 수집한다. 이를 통해 실시간 수집 데이터의 활용 기술을 이용하여 수집원 프로파일링을 통한 미디어별 수집 주기 산정하고 수집 엔진의 유연한 확장성을 활용한 실시간 수집 제반 기술 확대할 수 있다. 또한 지속적인 수집원 변경관리를 수행한다. 즉, 신규 생성, 변경, 삭제되는 사이트에 대한 변경관리를 수행하고 지속적인 수집량 모니터링을 통한 수집여부를 점검하며 수집 필터링 규칙에 대한 튜닝으로 데이터 품질 확보하도록 한다.

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Reduction of Ambiguity in Phosphorylation-site Localization in Large-scale Phosphopeptide Profiling by Data Filter using Unique Mass Class Information

  • Madar, Inamul Hasan;Back, Seunghoon;Mun, Dong-Gi;Kim, Hokeun;Jung, Jae Hun;Kim, Kwang Pyo;Lee, Sang-Won
    • Bulletin of the Korean Chemical Society
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    • v.35 no.3
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    • pp.845-850
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    • 2014
  • The rapid development of shotgun proteomics is paving the way for extensive proteome profiling, while providing extensive information on various post translational modifications (PTMs) that occur to a proteome of interest. For example, the current phosphoproteomic methods can yield more than 10,000 phosphopeptides identified from a proteome sample. Despite these developments, it remains a challenging issue to pinpoint the true phosphorylation sites, especially when multiple sites are possible for phosphorylation in the peptides. We developed the Phospho-UMC filter, which is a simple method of localizing the site of phosphorylation using unique mass classes (UMCs) information to differentiate phosphopeptides with different phosphorylation sites and increase the confidence in phosphorylation site localization. The method was applied to large scale phosphopeptide profiling data and was demonstrated to be effective in the reducing ambiguity associated with the tandem mass spectrometric data analysis of phosphopeptides.

Enhancement of Subgrade Stiffness Profiling by Incorporating Rayleigh and Love Waves into the Common-Array-Profiling(CAP) SASW Technique (레일레이파.러브파의 동시활용과 CAP SASW 기법 적용에 의한 지반 전단강성 평가의 고품질화)

  • Chang, Dae-Woo;Joh, Sung-Ho;Kang, Tae-Ho;Koh, Hak-Song
    • Proceedings of the Korean Geotechical Society Conference
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    • 2005.03a
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    • pp.338-345
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    • 2005
  • Recently, surface-wave methods have been widely used for site investigation due to economic advantage and improved reliability. Specially, the Spectral-Analysis-of-Surface-Wave (SASW) method has been used to evaluate soil properties in geotechnical engineering. In determination of subgrade stiffness by SASW measurements, only the vertical Rayleigh waves have been used. This study proposed a framework to determine shear-wave velocity profiles by using vertical and horizontal Rayleigh waves and Love wave all together. In addition, the Common-Array-Profiling(CAP) SASW method was employed, which subgrade stiffness of profile the local material under two fixed receivers. The procedure proposed in this study was verified by comparing the shear-wave velocity profiles with the shear-wave velocity profiles of downhole testing at two geotechnical sites.

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A Profiling Case Study to Phishing Mail Attack Group (피싱 메일 공격조직에 대한 프로파일링 사례 연구)

  • Lee, Jae-il;Lee, Yong-joon;Kwon, Hyuk-jin
    • Journal of Internet Computing and Services
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    • v.21 no.2
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    • pp.91-97
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    • 2020
  • Recently, phishing attacks targeting those involved in defense, security and unification have been on the rise. In particular, hacking attack organization Kimsuky has been engaged in activities to collect important information from public organizations through phishing attacks since 2013. In this paper, profiling analysis of phishing mail attack organization was performed. Through this process, we estimated the purpose of the attack group and suggested countermeasures.

LC-MS/MS Profiling-Based Secondary Metabolite Screening of Myxococcus xanthus

  • Kim, Ji-Young;Choi, Jung-Nam;Kim, Pil;Sok, Dai-Eun;Nam, Soo-Wan;Lee, Choong-Hwan
    • Journal of Microbiology and Biotechnology
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    • v.19 no.1
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    • pp.51-54
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    • 2009
  • Myxobacteria, Gram-negative soil bacteria, are a well-known producer of bioactive secondary metabolites. Therefore, this study presents a methodological approach for the high-throughput screening of secondary metabolites from 4 wild-type Myxococcus xanthus strains. First, electrospray ionization mass spectrometry (ESI-MS) was performed using extracellular crude extracts. As a result, 22 metabolite peaks were detected, and the metabolite profiling was then conducted using the m/z value, retention time, and MS/MS fragmentation pattern analyses. Among the peaks, one unknown compound peak was identified as analogous to the myxalamid A, B, and C series. An analysis of the tandem mass spectrometric fragmentation patterns and HR-MS identified myxalamid K as a new compound derived from M. xanthus. In conclusion, LC-MS/MS-based chemical screening of diverse secondary metabolites would appear to be an effective approach for discovering unknown microbial secondary metabolites.

Development of a Cybersecurity Workforce Management System (사이버 보안 분야 전문가 프로파일 관리 시스템 연구)

  • Ahn, Jun-young;Lee, Seung-hun;Park, Hee-min;Kim, Hyun-chul
    • Journal of the Semiconductor & Display Technology
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    • v.20 no.3
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    • pp.65-70
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    • 2021
  • According to the trend of increasingly sophisticated cyber threats, the need for technology research that can be applied to cyber security personnel management and training systems is constantly being raised not only overseas but also in Korea. Previously, the US and UK have already recognized the need and have been steadily conducting related research from the past. In the United States, by encouraging applications based on related research (NICE Cybersecurity Workforce Framework) and disclosing successful use cases to the outside, it is laying the groundwork for profiling cyber security experts. However in Korea, research on cyber security expert training and profiling is insufficient compared to other countries. Therefore, in this study, in order to create a system suitable for the domestic situation, research and analysis of cases in the United States and the United Kingdom were conducted over the past few years, and based on this, a prototype was produced for the study of profiling technology for domestic cyber security experts.

Molecular profiling of 18S rRNA reveals seasonal variation and diversity of diatoms community in the Han River, South Korea

  • Muhammad, Buhari Lawan;Lee, Yeon-Su;Ki, Jang-Seu
    • Journal of Species Research
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    • v.10 no.1
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    • pp.46-56
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    • 2021
  • Diatoms have been used in examining water quality and environmental change in freshwater systems. Here, we analyzed molecular profiling of seasonal diatoms in the Han River, Korea, using the hypervariable region of 18S V1-V3 rRNA and pyrosequencing. Physicochemical data, such as temperature, DO, pH, and nutrients showed the typical seasonal pattern in a temperate region. In addition, cell counts and chlorophyll-a, were recorded at high levels in spring compared to other seasons, due to the diatom bloom. Metagenomic analysis showed a seasonal variation in the phytoplankton community composition, with diatoms as the most frequently detected in spring (83.8%) and winter (69.7%). Overall, diatom genera such as Stephanodiscus, Navicula, Cyclotella, and Discostella were the most frequent in the samples. However, a large number of unknown Thalassiosirales diatoms were found in spring (35.5%) and winter (36.3%). Our molecular profiling revealed a high number of diatom taxa compared to morphological observation. This is the first study of diatoms in the Han River using molecular approaches, providing a valuable reference for future study on diatoms-basis environmental molecular monitoring and ecology.

Effect of Chlorella vulgaris on gut microbiota through a simulated in vitro digestion process

  • Jin, Jong Beom;Cha, Jin Wook;Shin, Il-Shik;Jeon, Jin Young;An, Hye Suck;Cha, Kwang Hyun;Pan, Cheol-Ho
    • Journal of Applied Biological Chemistry
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    • v.64 no.1
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    • pp.49-55
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    • 2021
  • The diet plays a fundamental role in the formation of the gut microbiota, determining the interrelationship between the gut microbiota and the host. The current study investigated the effect of Chlorella vulgaris on the gut microbiota by using simulated in vitro digestion and colonic fermentation. Bioaccessibility was measured after in vitro digestion, and SCFAs and microbial profiling were analyzed after colonic fermentation. The bioaccessibility of C. vulgaris was 0.24 g/g. The three major SCFAs (acetate, propionate, and butyrate) increased significantly when compared to the control group. In microbial profiling analysis, microorganisms such as Faecalibacterium, Dialister, Megasphaera, Dorea, Odoribacter, Roseburia, Bifidobacterium, Butyricmonas, and Veillonella were high in C. vulgaris group. Among them, Faecalibacterium, Dialister, Megasphaera, Roseburia, and Veillonella were thought to be closely associated with the increased level of SCFAs. Finally, it can be expected to help improve gut microbiota and health through ingestion of C. vulgaris. However, further studies are vital to confirm the changes in the gut microbiota in in vivo, when C. vulgaris is ingested.