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Predictive Factors of Blood Transfusion Requirement in Blunt Trauma Patients Admitted to the Emergency Room (응급실에 내원한 둔상환자의 수혈 필요성 예측인자)

  • Oh, Ji Sun;Kim, Hyung Min;Choi, Se Min;Choi, Kyoung Ho;Hong, Tae Yong;Park, Kyu Nam;So, Byung Hak
    • Journal of Trauma and Injury
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    • v.22 no.2
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    • pp.218-226
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    • 2009
  • Purpose: In multiple blunt trauma patients, transfusion may be a significant therapeutic adjunct to non-operative management. The blood products must be expedited and efficiently to patients in impending shock caused by hemorrhage or traumatic coagulopathy, but the decision to perform blood transfusion has been made empirically, based on the clinician' and has not been guided by objective parameters, but own opinion, that may result in an underestimate of or a failure to detect bleeding, in delayed transfusion, and in a reduced outcome. This article presents quickly assessable predictive factors for determining if a blood transfusion is required to improve outcomes in multiple blunt trauma patients admitted to the emergency room. Methods: In a retrospective review of 282 multiple blunt trauma patients who visited our emergency center by emergency rescuer during a 1-year period, possible factors predictive of the need for a blood transfusion were subjected to univariate and multivariate logistic regression analysis. Results: Of blunt trauma patients, 9.2% (26/282), received red blood cells in the first 24 hours of care. Univariate analysis revealed significant associations between blood transfused and heart rate (HR) > 100 beats/min, respiratory rate (RR) > 20 breaths/min, Glasgow Coma Scale (GCS) < 14, Revised Trauma Score (RTS) < 11, white blood cell count (WBC) < 4000 or > 10000, and initial abnormal portable trauma series (Cspine lateral, chest AP, pelvis AP). A multiple regression analysis, with a correction for diagnosis, identified HR > 100 beats/min (EXP 3.2), GCS < 14 (EXP 4.1), and abnormal trauma series (EXP 2.9), as independent predictors. Conclusion: In our study, systolic blood pressure (SBP) < 90 mmHg, old age > 65 years, hemoglobin < 13g/dL, mechanism of injury were poor predictors of early blood transfusion. Initial abnormal portable trauma series, HR > 100 beats/min, and GCS < 14 were quickly assessable useful factors for predicting a need for early blood transfusion in blunt trauma patients visiting the emergency room.

Problems and Solutions of Zymography Techniques (자이모그라피 기술의 문제점과 해결)

  • Kang, Dae-Ook;Choi, Nack-Shick
    • Journal of Life Science
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    • v.29 no.12
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    • pp.1408-1414
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    • 2019
  • Enzymes are widely used in industrial applications such as detergents, food, feed production, pharmaceuticals and medical applications and major contributors to clean industrial products and processes. To screen, identify, and characterize the enzymes the zymography techniques are routinely used. The zymography technique is a simple, sensitive, and quantifiable technique that is widely used to detect functional enzymes following electrophoretic separation in sodium dodecyl sulfate (SDS)-polyacrylamide gels. The method is a versatile two-stage technique involving protein separation by electrophoresis followed by the detection of enzyme activity in polyacrylamide gels under non-reducing conditions. It is based on SDS-polyacrylamide gel (PAG) copolymerization with substrates, which are degraded by the hydrolytic enzymes restored in enzyme reaction buffer after the electrophoretic separation. Any kind of biological sample can be applied and analyzed on zymography, including culture supernatants of microbes, plants extracts, blood, tissue culture fluids, enzymes in foods extracts and metaproteome. The advantage of zymography is that it is possible to directly detect the protein with activity on the electrophoretic gel as well as confirm the activity at the nanogram level. Thus, this zymography technology can be applied in various fields. However, these advantages are rather disadvantageous and can often lead to experimental errors. In this review, the advantages, disadvantages, and problem solving of zymography technique are described.

Development of Metabolic Engineering Strategies for Microbial Platform to Produce Bioplastics (바이오플라스틱 생산 미생물 플랫폼 제작을 위한 대사공학 전략 개발)

  • Park, Si Jae;David, Yokimiko;Baylon, Mary Grace;Hong, Soon Ho;Oh, Young Hoon;Yang, Jung Eun;Choi, So Young;Lee, Seung Hwan;Lee, Sang Yup
    • Applied Chemistry for Engineering
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    • v.25 no.2
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    • pp.134-141
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    • 2014
  • As the concerns about environmental problems, climate change and limited fossil resources increase, bio-based production of chemicals and polymers from renewable resources gains much attention as one of the promising solutions to deal with these problems. To solve these problems, much effort has been devoted to the development of sustainable process using renewable resources. Recently, many chemicals and polymers have been synthesized by biorefinery process and these bio-based chemicals and plastics have been suggested as strong candidates to substitute petroleum-based products. In this review, we discuss current advances on the development of metabolically engineered microorganisms for the efficient production of bio-based chemicals and polymers.

Developing an Assortment Planning Process Model for Clothing Retail Buyers: An Exploratory Research

  • Kang, Keang-Young;Kincade, Doris H.
    • Fashion & Textile Research Journal
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    • v.6 no.6
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    • pp.815-824
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    • 2004
  • In academic and/or practitioner literature, the assortment planning for fashion sensitive products is rarely systematically studied, and organized in an objective format. The purpose of this study was to develop a suggested assortment planning model for women's clothing retail buyers by integrating a conceptual assortment planning model and a practical-use assortment planning model, which are also developed in this study. In developing the conceptual model, this research categorized and organized the pieces of assortment planning activities illustrated in available literature. In developing the practical-use model, ten women's dress buyers from department stores and specialty stores were interviewed. The contents of the interview dictation were classified and summarized by concepts and variables. The summary was validated by the interviewees and recontextualized for the practical-use model. Five experts compared the conceptual and practical-use models, adjusted the discrepancies, and integrated into the suggested model. In addition, a questionnaire asking review of all functional activities of the suggested model was sent to interviewees to ascertain its validity. As the result, assortment planning process was determined at abstract level as the following: (a) recognize problem, (b) search for information, (c) evaluate qualitative value of product, (d) evaluate quantitative value of product, (e) plan product selection, and (f) plan sales.

The Development of Tobacco Litigation in USA and it's Impact of Law and Politics in Public Health (미국 담배소송의 변천과 보건법정책 효과)

  • Kim, Un-Mook;Kim, Ji-Hyun
    • The Korean Society of Law and Medicine
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    • v.12 no.1
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    • pp.133-173
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    • 2011
  • Since mid-1960s the reports from the Surgeon General, the World Health Organization, and other health experts state that there is no risk-free level exposure to smoking and secondhand smoke. Tobacco smoke is made up of more than 7,000 chemicals. Hundreds are toxic, and at least 70 are carcinogens. The chemicals in tobacco smoke reach smoker's lungs quickly every time smoker inhale causing damages immediately. Inhaling even the smallest amount of tobacco smoke can also damage smoker's DNA, which can lead to cancers. Smoking is responsible for more than 87% of lung cancers, but there are a host of other chronic diseases directly related to exposure to tobacco smoke. It's also a major cause of heart disease, stroke, aortic aneurysm, peripheral arterial disease and most of the other diseases. In the United States, each year with more than from 440,000 to 520,000 deaths caused by smoking and exposure to involuntary smoke. They conclude that smoking is the single most important source of preventable morbidity and mortality. The United States of America have about 60-year history of tobacco litigation. Tobacco litigation has been an important tool in tobacco control strategies aimed at limiting the activities of tobacco companies and providing redress to people who have become ill as a result of their use of tobacco products. Tobacco litigation is a kind of tort litigation. Quite often, as in the asbestos and other mass tort litigation episodes, tobacco litigation can play an educational role, warning the public about the magnitude of health risks that might otherwise be less clearly perceived. Tobacco litigation allows smokers, their families or other victims of smoking to sue tobacco companies in order to be compensated for the harm they have suffered. Potential benefits of tobacco litigation include compensation for smoking-related damages, strengthening regulatory activity, publicity, documents disclosure and changing tobacco industry behavior. And also tobacco litigation can limit the political activities of tobacco industry, protect human rights of smokers and non-smokers, increase burden to tobacco price-up and enhance the effects of law and politics in public health.

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The Study on Treatment of Poultry Waste by Earthworms, and the Effect of Feeding Earthworms Meal on the Performance of Broilers and Laying Hens, and Safety of Meat and Egg (지렁이를 이용한 계분처리 그리고 지렁이를 이용한 계육 및 계란의 생산과 안전성에 관한 연구)

  • Son, Jang-Ho
    • Korean Journal of Organic Agriculture
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    • v.17 no.1
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    • pp.63-82
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    • 2009
  • This review was conducted to the study on treatment of poultry waste by earthworms, and the effect of feeding earthworms meal on the performance of broilers and laying hens, and safety of meat and egg. 1. The pro-environmental chicken house was building in Daegu National University of Education, Daegu city, chicken wastes will be turn into high quality compost by vermicomposting uses earthworms in the house. 2. The earthworm meal (EWM) has a high proteinic content and a balanced amino acid and fatty acid profile, therefore most feeding applications has been evaluated with mono-gastric animals. 3. The dietary supplementations of 0.2 to 0.4% EWM were effective in improve digestibility of crude protein of diet resulted improved broiler performance in broiler chickens. 4. The supplementing 0.2 to 0.6% of earthworm meal in the laying hens diet, improves the laying performance and egg quality, especially ratio of egg yolk n-6/n-3 fatty acids contents. 5. As, Cd, Cr, Hg and Pb were detected at level of 4.41, 1.23, 1.18, 0.00 and 3.39ppm in earthworm meal, respectively, but those were not detected in the chicken meat and egg. therefore supplementing 0.6% of EWM in the chicken diet, it still did not affect meat and egg safety. 6. These results indicated that vermicompositing uses earthworms good a subject matter in the pro-environmental animal husbandry.

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CO2 Emission Structure Analysis with Environmental Input-Output Table 2000 (환경산업연관표 2000을 이용한 산업부문의 이산화탄소(CO2) 발생 분석)

  • Kim, Yoon Kyung
    • Environmental and Resource Economics Review
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    • v.15 no.3
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    • pp.425-450
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    • 2006
  • The index of energy intensity(energy/GDP) has been a primary policy concern since it can clarify industry sectors which use energy intensively and generate $CO_2$ emission heavily. Although energy intensity index may be suitable for estimating $CO_2$ emission from an isolated industry sector, we need an index for induced $CO_2$ emission since industrial activities are interconnected in terms of input and output. By employing Environmental Input-Output Table 2000, this paper analyses the flow of energy demand and pollutants after first estimating an induced $CO_2$ emissions from various industrial sectors and economic activities. The paper reports higher induced $CO_2$ emissions from industry sectors with larger energy intensity since they produces goods or services retaining relatively considerable environmental load. Furthermore, it is shown that environmental load and $CO_2$ emissions in overall economy are likely increasing when the products of energy intensive industrial sector is used as inputs for less intensive sectors' production process. The result suggests we need consistent policy efforts to reduce energy intensity to lower $CO_2$ emissions.

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A Study to Promote the Export of Korean Hang Over Drinks in Russia (숙취해소음료의 러시아권 시장 수출활성화 방안)

  • Kim, Jihoon;Lim, Sungsoo
    • Journal of Convergence for Information Technology
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    • v.10 no.4
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    • pp.35-45
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    • 2020
  • To diversify the agro-food exports of Korea, this study selected Russia, which is located closet to CIS countries, as a sampling area and sought ways to promote the export of Korean hang over drinks to Russia. This study analyzed the contributing factors to the export, such as Russian consumers' purchasing intentions, as well as the willingness to pay of korean hang over drinks in Russia, using the paper review and on-off line survey data correction method. Major results are as follows. First, Russian consumers' intention of purchasing Korean hang over drinks is higher than Europe and the other products. Therefore, it is necessary to understand the demographic characteristics of Russian consumers and then actively use niche marketing strategies. Second, the purchase intention of Russian consumers towards increased when buying behavior occurred in supermarket, hypermarket- and convenience stores. Third, it seems prefer to pricing of Korean hang over drinks in Russian export market similar to the domestic price level.

The Structural Relationships among the Related Variables of University Students' Satisfaction (대학생의 만족도와 관련된 변인들 간의 구조적 관계)

  • Son, Kyung-Ae;Lee, Deog-Ro
    • Management & Information Systems Review
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    • v.32 no.4
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    • pp.1-25
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    • 2013
  • The purpose of this study was to test the structural relationships among the related variables of university students' satisfaction. This study utilized nation-wide survey data previously collected from 1400 students distributed across 32 universities in Korea. NCSI model was used as a theoretical framework. Using the AMOS 17.0, the structural relationships among six variables were tested, including students' expectancy level, perceived quality, perceived value, satisfaction, complaint rate, and loyalty. The major findings of the study are as follows: First, students' expectancy level had a positive effect on perceived quality; but had no significant effect either on perceived value or on satisfaction. Second, perceived quality had positive effects on perceived value and satisfaction; and perceived value also had a positive effect on satisfaction. Third, students' satisfaction had a negative effect on complaint rate; but had a positive effect on loyalty. Fourth, students' complaint rate had a negative effect on loyalty. The study results imply that among the related variables of students' satisfaction, perceived quality and value of the products work as critical variables, and complaint rate and loyalty directly relate to students' satisfaction. The study suggested that in order to enhance students' satisfaction, universities employ the total quality system and the students' complaints resolution system.

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Value-added Chemicals Derived from Propane Using Heterogeneous Catalysts (불균일계 촉매를 통한 프로판 고부가화)

  • Yoon, Ji-Sun;Suh, Dong-Jin;Park, Tae-Jin;Cho, Young-Sang;Suh, Young-Woong
    • Clean Technology
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    • v.14 no.2
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    • pp.71-86
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    • 2008
  • In this review we discussed the effective ways to catalytically derive value-added chemicals from propane which has been utilized only as an energy source so far. Among various propane-derived products, the most valuable chemicals such as propylene and acrylonitrile were mainly focused herein. Propylene could be manufactured through oxidative dehydrogenation of propane using $O_2,\;CO_2$, etc. as an oxidant for the purpose of overcoming thermodynamic limitations of propane dehydrogenation. On the other hand, propane ammoxidation would be an alternative to propylene ammoxidation for producing acrylonitrile since propane is much cheaper than propylene as a starting material. Although effective $MoVTeNbO_x$ catalysts have been developed fur propane ammoxidation in recent years, more detailed studies should be thoroughly performed. In carrying out both oxidative dehydrogenation and ammoxidation of propane fur a long period, the most critical issue is definitely considered to find out the most active and selective catalysts, which makes it possible to commercialize both reactions into economically viable processes.

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