• 제목/요약/키워드: Product similarity

검색결과 295건 처리시간 0.043초

작약의 혈소판 응집억제작용에 관한 연구 (Study on Inhibition of Platelet Aggregation of Bioactive Constituents from Paeonia lactiflora)

  • 박관혁;서범석;손동주;박영현;장성근
    • 한국산학기술학회논문지
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    • 제4권4호
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    • pp.357-360
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    • 2003
  • 작약의 methanol 추출물은 혈소판 활성 실험에서 혈소판 응집에 대해 강한 억제를 보였다. 활성성분은 chromatography방법을 사용하여 정제하였고 NMR과 기존의 Data로 분석하였다. Compound 1b는 benzoyloxypaeoniflorin과 동일한 구조임을 확인하였으며. compound 2e는 작약의 주성분인 paeoniflorin과 동일한 화학구조를 가졌으며 , compound 3a의 분석결과 구조적 유사성은 있으나 동일한 구조식은 확인 할 수 없었지만 collagen에서 응집억제활성이 90%이상의 뛰어난 활성을 나타내어 benzoyloxypaeoniflorin과 유사하게 benzoyl 기가 다른 작용기로 치환되었거나 Rl group이 다른 작용기로 치환된 형태로 추측하였다. Paeoniflorin이 collagen보다 thrombin에서 강한 억제를 보이는 것은 Ca/sup 2+/ chelate를 형성함으로 인해 calcium 대사산물이 파괴된 것으로 추측했다. Compound 3a는 paeoniflorin의 benzoyl 기에 있는 OH기나 paeoniflorin의 glycoside 5-carbon위치의 OH기 대신에 다른 작용기가 대사산물로의 역할을 수행했을 것으로 추정했다.

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홍조류로부터 신규 한천분해미생물 Alteromonas macleodii subsp. GNUM08120의 분리 및 동정 (Isolation and Characterization of a Novel Agar Degrading Bacterium, Alteromonas macleodii subsp. GNUM08120, from Red Macroalgae)

  • 지원재;임주현;박다연;김무찬;김창준;장용근;홍순광
    • 한국미생물·생명공학회지
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    • 제41권1호
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    • pp.8-16
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    • 2013
  • An agar-hydrolyzing marine bacterium, strain GNUM08120, was isolated from Sargassum fulvellum collected from Yeongil bay of East Sea of Korea. The isolate was Gram-negative, aerobic, motile with single polar flagellum, and grew at 1-10% NaCl, pH 5.0-8.0, and $15-37^{\circ}C$. G+C content and the predominant respiratory quinone were 46.13 mol% and Q-8, respectively. The major cellular fatty acids were Summed feature 3 (24.5%), $C_{16:0}$ (21.7%), and $C_{18:1}{\omega}7c$ (12.5%). Based on 16S rRNA gene sequence similarity and DNA-DNA hybridization analyses, strain GNUM08120 was identified as a novel subspecies of Alteromonas macleodii, designated Alteromonas macleodii subsp. GNUM08120. Production of agarase by strain GNUM08120 was likely repressed by the effect of carbon catabolite repression caused by glucose. The crude agarase prepared from 12-h culture broth of strain GNUM08120 exhibited an optimum pH and temperature for agarase activity at 7.0 and $40^{\circ}C$, respectively. The crude enzyme produced (neo)agarobiose, (neo)agarotetraose, and (neo)agarohexaose as the hydrolyzed product of agarose.

HYPERSPECTRAL IMAGERY AND SPECTROSCOPY FOR MAPPING DISTRIBUTION OF HEAVY METALS ALONG STREAMLINES

  • Choe, Eun-Young;Kim, Kyoung-Woong;Meer, Freek Van Der;Ruitenbeek, Frank Van;Werff, Harald Van Der;Smeth, Boudewijn De
    • 대한원격탐사학회:학술대회논문집
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    • 대한원격탐사학회 2007년도 Proceedings of ISRS 2007
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    • pp.397-400
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    • 2007
  • For mapping the distribution of heavy metals in the mining area, field spectroscopy and hyperspectral remote sensing were used in this study. Although heavy metals are spectrally featureless from the visible to the short wave infrared range, possible variations in spectral signal due to heavy metals bound onto minerals can be explained with the metal binding reaction onto the mineral surface. Variations in the spectral absorption shapes of lattice OH and oxygen on the mineral surface due to the combination of heavy metals were surveyed over the range from 420 to 2400 nm. Spectral parameters such as peak ratio and peak area were derived and statistically linked to metal concentration levels in the streambed samples collected from the dry stream channels. The spatial relationships between spectral parameters and concentrations of heavy metals were yielded as well. Based on the observation at a ground level for the relationship between spectral signal and metal concentration levels, the spectral parameters were classified in a hyperspectral image and the spatial distribution patterns of classified pixels were compared with the product of analysis at the ground level. The degree of similarity between ground dataset and image dataset was statistically validated. These techniques are expected to support assessment of dispersion of heavy metal contamination and decision on optimal sampling point.

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의류점포서비스가 의복충동구매행동에 미치는 영향 (The Effects of Apparel Store Services on Impulsive Buying Behaviors)

  • 최영은;박은주
    • 한국의류학회지
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    • 제26권11호
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    • pp.1615-1626
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    • 2002
  • The purpose of this study was to investigate the effect of shopping orientation, and service quality and satisfaction on impulsive buying behavior in two types of apparel store. The sample consisted of 616 females aged 20-30 who were shopping at department stores and shopping malls in Busan. Data were analyzed with factor analysis, t-test, cross analysis and path analysis. The results showed that consumers of department stores showed more strongly convenient orientation than those of the shopping mall, consumers of the shopping mall showed more strongly recreational orientation and practical orientation than those of the department. Stores services of the department were perceived better than that of the shopping mall in promotional services, salespersons' services and environmental services. But it didn't show any differences between store types in product services. Consumers 'satisfaction with the service was greater in department stores than the shopping mall. But it didn't show any difference between apparel store types in the impulsive buying behaviors. Impulsive buying behavior of department store shoppers is directly affected by a shopper' shopping orientation as well as store service quality perceived by shoppers rather than a shopper' satisfaction. The service quality does not have directly related to consumers’ service satisfaction. The causal relationships of impulsive buying behaviors showed similarity in shopping malls and department stores. The perceived quality and satisfaction with store service were higher at department store than shopping malls. In impulse buying behavior of a department store was directly affected by a shopper' shopping orientation as well as store service quality perceived by shoppers rather than a shopper’ store service satisfaction.

Ligustici Rhizoma(고본(藁本))와 Angelica tenuissimae Radix(한국고본(韓國藁本)뿌리)의 규격화(規格化) 및 유효성분(有效成分)의 진통효과(鎭痛效果) 비교(比較)에 관한 연구(硏究) (A Study on the Standardization of Ligustici Rhizoma and Angelicae Tenuissimae Radix including the Comparison for the Biological Activity on the Active Ingredients)

  • 김관호;이상인;김호철;박호군;이재성
    • 대한한의학회지
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    • 제18권1호
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    • pp.187-197
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    • 1997
  • Major separation for the active ingredients and characterization of chemical properties in conjunction with screening test on animal were performed in order to analyze and standardize Ligustici Rhizoma or Angelicae Tenuissimae Radix as an important oriental herbal medicine for antiphlogistic or an important oriental herbal medicine for antiphlogistic or an anodyne. Furthermore the structure, composition and contents of ingredients for essential oil in Angelicae Tenuissimae Radix(Suckpo, Korea) were determined by means of Ge/MS followed by screening test on Z-ligustilide(82%) known as major ingredient as well as butylidenephthalide collected by HPLC with normal phase semiprep-column. The total active ingredient in Ligustici Rhizoma from China or Angelicae Tenuissimae harvested at Choonyang(Kyungnam, Korea), Jungsun(Kangwon, Korea), Suckpo(Kyungnam Korea), Youngchun(Kyungnam, Korea) have been determined showing higher abundant for three times on the product in Korea compared to that in China. In addition, the major component in Ahgelicae Tebyussunae Radux extract was found to be Z-ligustilide(70-80%) which is very different from that in Ligustici Rhizoma senkyunolide(39%) as major species. For screening test of Ligustici Rhizoma or Angelicae Tenuissimae Radix extracts toward the target animal, the efficiency has been shown the similarity on both extracts. Taking into account the level of ingredient, the total efficiency may be three times higher on Angelicae Tenuissimae Radix in Korea compared to Ligustici Rhizoma in China. As a result of present study, it is preferable to distinguish between Ligustici Rhizoma and Angelicae Tenuissimae Radix for better usage of oriental herbal medicine because of very different composition and abundant in spite of their similar screening effect.

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상호 이익을 위한 학습 에이전트 기반의 효율적인 다중 속성 협상 시스템 (An Efficient Multi-Attribute Negotiation System using Learning Agents for Reciprocity)

  • 박상현;양성봉
    • 정보처리학회논문지D
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    • 제11D권3호
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    • pp.731-740
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    • 2004
  • 본 논문에서는 상거래에 참여한 구매자와 판매자가 협상을 통하여 서로의 이익을 보장하면서 합의를 도출 할 수 있는 협상 에이전트 시스템을 제안하였다. 제안 시스템은 기존의 협상 에이전트 시스템에 기계 학습을 적용함으로써, 학습 에이전트의 도입이 협상의 효율성에 어떤 영향을 미치는지 고찰하고자 하였다. 구매자 및 판매자 에이전트는 상품의 다중 속성을 고려하여 협상을 수행하며, 구매자와 판매자의 이익은 Multi-Attribute Utility Theory를 이용하여 표현하였다. 본 연구에서 제시된 학습 가능한 협상 에이전트는 Faratin이 제안한 협상 시스템의 제안 생성(counter offer) 과정에 인공신경망을 통한 점진적 학습 기업을 추가함으로써 협상의 효율성을 증가시키는데 목적이 있다. 점진적 학습기법을 이용한 협상 에이전트 시스템의 경우, 동일한 협상 조건 하에서 상대방 제안과의 유사도(similarity)를 바탕으로 제안을 생성하는 기존의 다른 협상 에이전트 시스템과 비교하였을 때 좋은 협상 결과를 보여 주었으며, 협상 수행시간에 있어서는 매우 빠른 성능을 보여주었다. 따라서 협상 결과 및 협상 수행 시간을 동시에 고려하였을 때 기존의 협상 시스템에 비하여 효율적인 협상 능력을 보여 주었다.

PCR-RFLP and Sequence Analysis of the rDNA ITS Region in the Fusarium spp.

  • Min, Byung-Re;Lee, Young-Mi;Choi, Yong-Keel
    • Journal of Microbiology
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    • 제38권2호
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    • pp.66-73
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    • 2000
  • To investigate the genetic relationship among 12 species belonging to the Fusarium section Martiella, Dlaminia, Gibbosum, Arthrosporiella, Liseola and Elegans, the internal transcribed spacer(ITS) regions of ribosomal DNA (rDNA) were amplified with primer pITS1 and pITS4 using the polymerase chain reaction(PCR). After the amplified products were digested with 7 restriction enzymes, restriction fragment length polymorphism (RFLP) patterns were analyzed. The partial nucleotide sequences of the ITS region were determined and compared. Little variation was observed in the size of the amplified product having sizes of 550bp or 570bp. Based on the RFLP analysis, the 12 species studied were divided into 5 RFLP types. In particular, strains belonging to the section Martiella were separated into three RFLP types. Interestingly, the RFLP type of F. solani f. sp. piperis was identical with that of isolates belonging to the section Elegans. In the dendrogram derived from RFLP analysis of the ITS region, the Fusarium spp. examined were divided into two major groups. In general, section Martiella excluding F. solani f. sp. piperis showed relatively low similarity with the other section. The dendrogram based on the sequencing analysis of the ITS2 region also gave the same results as that of the RFLP analysis. As expected, 5.8S, a coding region, was highly conserved, whereas the ITS2 region was more variable and informative. The difference in the ITS2 region between the length of F. solani and its formae speciales excluding F. solani f. sp. piperis and that of other species was caused by the insertion/deletion of nucleotides in positions 143-148 and 179-192.

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다중 바코드 영역을 가지는 영상에서 지역적 픽셀 방향성을 이용한 바코드 관심 영역 추출 방법 (Barcode Region of Interest Extraction Method Using a Local Pixel Directions in a Multiple Barcode Region Image)

  • 조호상;강봉순
    • 한국정보통신학회논문지
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    • 제19권9호
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    • pp.2121-2128
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    • 2015
  • 본 논문에서는 공장 자동화를 위한 신뢰성 높은 바코드 관심영역 추출 방법을 제안한다. 방향성분 추출 및 검출할 바코드의 특성을 이용하여 배경을 분리한다. 관심영역 후보 영상의 blur, 회전, 유사영역등으로 인한 문제점을 분석하여 후보정하는 작업을 수행한다. 또한 빠른 연산 속도를 위해 resizing factor를 사용하여 영상 resizing 연산을 통한 빠른 연산이 가능하도록 하였다. 다양한 자동화 환경에 적용 가능한 연배열과 같이 다수의 제품이나 바코드가 입력 영상에 촬영되고 촬영 거리가 최대 80cm 임에도 높은 추출 성공률이 가능도록 하였다. 다양한 거리에서 촬영된 영상을 시뮬레이션 한 결과 관심영역 검출률은 100%, 후보정 성공률은 99.3%인 것을 확인하였다.

스마트 팩토리 망에서 DPI와 자기 유사도 기술 기반의 OPC-UA 프로토콜 게이트웨이 융합 보안 기술 (Convergence Security Technology of OPC-UA Protocol Gateway based on DPI & Self-Similarity for Smart Factory Network)

  • 심재윤;이준경
    • 정보보호학회논문지
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    • 제26권5호
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    • pp.1305-1311
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    • 2016
  • 스마트 팩토리는 제품의 전 생산 과정에 정보통신기술(ICT: Information and Communications Technologies)을 접목하여, 생산 비용의 절감 및 공정 개선 등을 이룰 수 있는 지능형 공장을 의미한다. 스마트 팩토리를 구현하기 위해서는 필연적으로 내부 설비들이 외부 네트워크와 연결되어야 하며, 이는 기존 폐쇄 망으로 운영되던 설비들이 외부 네트워크에 노출됨으로써 보안 취약성 증가하게 된다. 이러한 문제점을 해결하기 위해서 일반 네트워크에 사용하고 있는 보안 장비를 적용할 수는 있으나 이 방법만 가지고는 스마트 팩토리 망에서의 보안 위협을 완벽하게 차단하는 것은 불가능하며 보안 침해 사고가 발생 시 물리적, 경제적 피해는 산정할 수 없을 정도로 클 것이다. 이에 본 논문에서는 스마트 팩토리에 적용 가능한 보안 기법들을 알아보며 안전한 스마트 팩토리를 위한 전용 보안 게이트웨이 및 보안 게이트웨이가 가져야할 주요 융합 보안 기술을 제안한다.

A Web-based CBR System for e-Mail Response

  • Yoon, Young-Suk;Lee, Jae-Kwang;Han, Chang-Hee
    • 한국산학기술학회:학술대회논문집
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    • 한국산학기술학회 2003년도 Proceeding
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    • pp.185-190
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    • 2003
  • Due to the rapid growth of Internet, means of communication with customers in a traditional customer support environment such as telephone calls are being replaced by mainly e-mail in a Web-based customer support system. Although such a Web-based support is efficient and promises potential benefits for firms, including reduced transaction costs, reduced time, and high quality of support, there are some difficulties associated with responding to many types of customer’s inbound e-mails appropriately .As many types of e-mail are received, considerable attention is being paid to methods for increasing the efficiency of managing and responding e-mails. This research proposes an intelligent system for managing customer’s inbound e-mails in organizations by applying case based reasoning technique for responding to various customers' inbound e-mails more effectively. In this approach, a case is represented as a frame-typed data structure corresponding to an inbound e-mail, keywords, and its reply e-mail. In the retrieval procedure, keywords and affinity set is developed to index a case, and then the case is represented as a vector, a case vector. Also, cosines value is calculated to measure the similarity between a new inbound e-mail and the cases in the case base. In the adaptation procedure, we provide several adaptation strategies to adapt and modify the retrieved case. The strategies guide to make an outbound e-mail using product databases, databases for customer support, etc. Additionally, the Web-based system architecture is proposed to implement our methodology. The proposed methodology and system will be helpful for developing more efficient Web-based customer support.

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