• Natural Product Sciences
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• 제21권2호
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• pp.98-103
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• 2015

Pueraiae Radix (PR), Pueratia Folium (PF) and Sorbus commixta (SC) mixture, namely GS-SP (PR (1)/PF (2)/SC (0.5): v/v/v) was developed as hangover-relieving elixir and its effects on alcoholic metabolism have been investigated. The enzymatic activity of alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH) of GS-SP was shown higher than those of single treatment with PR, PL, SC, and the positive control group (YM-808). The survival rate of mouse liver cell line NCTC clone 1469 in the presence of acetaldehyde was 30.6, 22.2, and 8.7% at the GS-SP dosage level of 50, 100, and 200 μg/mL respectively. Different concentrations of 50, 100 and 200 mg/kg of GS-SP showed efficient activity for ADH and ALDH than YM-808 in rat fed with 25% ethanol. The levels of blood alcohol and acetaldehyde after oral administration of 200 mg/kg of GS-SP showed efficient activity of 11.7% and 37% than those of YM-808. These results have been supported to the potential for GS-SP to serve as an excellent potential in providing hangover relief and liver protection.

• 한국정밀공학회지
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• 제19권2호
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• pp.114-125
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• 2002

As semi-solid forging (SSF) is compared with conventional easting such as gravity die-easting and squeeze casting, the product without inner defects can be obtained from semi-solid forming and globular microstructure as well. Generally speaking. SSF consists of reheating, forging, ejecting precesses. In the reheating process, the materials are heated up to the temperature between the solidus and liquidus line at which the materials exists in the form of liquid-solid mixture. The process variables such as reheating time, reheating temperature, reheating holding time, and induction heating power have much effect on the quality of the reheated billets. It is difficult to consider all the variables at the same time when predicting the quality. In this paper, Taguchi method, regression analysis and neural network were applied to analyze the relationship between processing conditions and solid fraction. A356 alloy was used for the present study, and the learning data were extracted by the reheating experiments. Results by neural network were on good agreement with those by experiment. Polynominal regression analysis was formulated by using the test data from neural network. Optimum processing condition was calculated to minimize the grain size, solid fraction standard deviation, otherwise, to maximize the specimen temperature average. In this time, discussion is liven about reheating process of row material and results are presented with regard to accurate process variables for proper solid fraction, specimen temperature and grain size.

• 상하수도학회지
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• 제19권1호
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• pp.68-77
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• 2005

This study was performed to evaluate the application of corrosion inhibitor and to examine the correlation between corrosion rate and red water in a series of batch tests and a test using auto corrosion monitoring system at A water treatment plant in Gyeonggido. The corrosion study in the auto corrosion monitoring system indicated that Fe concentration decreased by 30~50% and corrosion rate also reduced remarkably with corrosion inhibitor at $1.8mg\;PO_4/L$. After addition of corrosion inhibitor, it was indicated the effective adsorption of the inhibitor on the surface of the pipe line forming a protective film. The corrosion rate increases with the increase in Fe concentration. With $1.8mg\;PO_4/L$ of corrosion inhibitor, the corrosion rate decreased remarkably. Fe concentration had correlation to not only red water problems but also the corrosion rate that actually dissolved into the water, primarily due to the deposition of oxidized iron or other compounds as a scale, which serves as a large reservoir of corrosion by-product. Therefore, corrosion rate can be estimated by Fe concentration. For these reasons, an effective corrosion inhibitor is also an effective red water control reagent. The effect of the corrosion inhibition can last for some time even the application the corrosion inhibitor is discontinued. For the cost effective and efficient corrosion control, the concentration and timing of corrosion inhibitor addition must be determined properly.

• Journal of the Korean Wood Science and Technology
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• 제17권2호
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• pp.20-25
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• 1989

This study was carried out in order to investigate the treatment effect of PEG soln which is a common dimensional stabilizer to green log. sawing panel etc, on bonding product including plywood widely-used in secondary processing unit. The 30% concentration of aqueous PEG soln. with molecular weight of 400, 1.000 and 4,000 were prepared respectively, and also dipping the veneer in the PEG soln. spreading the PEG soln. on veneer and mixing the PEG soln. in the adhesive were allowed. Then the ratio of PEG impregnation on veneer, the adhesive strength of plywood were epitomized as follows: The ratio of impregnation by PEG 4,000 at dipping condition was highest. while that by PEG 400 at same condition was lowest. However, the effect of PEG molecular weight on the ratio of impregnation at spreading condition did not occur. 2. The adhesive strength was great in the order of 4,000>400>1,000 in molecular weight of PEG at dipping and spreading conditions. In case of mixing the PEG soln. in the adhesive, the adhesive strength was great in the order of 400>1,000>4,000 in molecular weight of PEG. Throughout three treatment conditions, PEG 400 was relatively favourable with about 10kg/$cm^2$ dry strength. 3. The adhesive strength was great 10 the order of spreading >dipping >mixing condition. 4. Although adhesive strength with the 30% concentration of aqueous PEG soln. was decreased by 35% and over, compared to control (non-treatment) adhesive strength, all types of PEG treatment except mixing the PEG soln. in the adhesive exceeded the standard dry strength for common use panel. 7.5kg/$cm^2$. 5. In warm water-proof test, the adhesive strengths by all PEG treatment conditions were less than the standard wet strength, 7.5kg cot, and also delamination of glue line occured mostly in mixing in the PEG soln. in the adhesive condition.

• BMB Reports
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• 제34권2호
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• pp.176-181
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• 2001

Using a retrovirus, foreign genes can be introduced into mammalian cells. The purpose of this study is to produce a retrovirus that can make the infected cells express two genes; the human multidrug resistance gene (MDR1) and the HLA-B7 gene, which is one of the major human histocompatibility complex (MHC) class I genes. For the expression of these genes, the internal ribosome entry site (IRES) was used, which was derived from the encephalomyocarditis (EMC) virus. In order to produce retroviruses, a retroviral vector was transfected into a packaging cell line and the transfected cells were treated with vincristine, which is an anti-cancer drug and a substrate for the MDRI gene product. This study revealed that two genes were incorporated into chromosomes of selected cells and expressed in the same cells. The production of the retrovirus was confirmed by the reverse transcription (RT)-PCR of the viral RNA. The retrovirus that was produced infected mouse fibroblast cells as well as the human U937. This study showed that packaging cells produced the retroviruses, which can infect the target cells. Once the conditions for the high infectivity of retrovirus into human cells are optimized, thus virus will be used to infect hematopoietic stem cells to co-express MDRl and HLA-B7 genes, and develop the lymphocytes that can be used for the immnogene therapy.

• 생약학회지
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• 제38권2호통권149호
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• pp.170-175
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• 2007

Activated microglia by neuronal injury or inflammatory stimulation overproduce nitric oxide (NO) by inducible nitric oxide synthase (iNOS) and reactive oxygen species (ROS) such as superoxide anion, resulting in neurodegenerative diseases. The toxic peroxynitrite (ONOO$^-$), the reaction product of NO and superoxide anion further contributes to oxidative neurotoxicity. We tried to evaluate the effects of two kinds of varieties of Perilla frutescens var japnica Hara on the NO production in lipopolysaccharide (LPS)-activated microglia. The perilla cultivars of Namcheondeulkkae (NC) and Boradeulkkae (BR) were developed by pure line from the local variety and by a cross between 'deulkkae' and 'chajogi', respectively. Spirit, hexane, chloroform and butanol fractions of the leaves of NC and BR inhibited the production of NO in LPS-activated microglia. The fractions of BR showed stronger activity than NC and the spirit extracts was the most potent in both cultivars. The solvent fractions of BR suppressed the expression of protein and mRNA of iNOS in LPS-activated microglial cells. Moreover, the extracts of NC and BR showed the activity of peroxynitrite scavenging in cell free bioassay system. These results imply that Namcheondeulkkae and Boradeulkkae might have neuroprotective activity through the inhibition of NO production by activated microglial cells and peroxynitrite scavenging activity.

• 한국전자통신학회논문지
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• 제9권4호
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• pp.447-454
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• 2014

최근에 양자회로 합성과 관련한 대부분의 방법들은 컴퓨터 시뮬레이션에 적합한 서술적 표현 구조를 채택하고 있어 합성된 양자함수들에 대한 분석이 어렵다. 본 논문에서는 구조가 단순하고 직관적 사고가 가능한 양자회로의 새로운 함수표현법을 제안한다. 본 논문 제안사항은 타깃라인상의 유니터리 연산자들의 직렬 적 행렬연산을 멱함수의 산술연산과 modulo 2 연산이란 수학적 치환을 통해 유니터리 연산자의 제어입력을 자신의 멱함수로 합성하는 새로운 함수합성에 있다. 본 논문의 함수합성 알고리듬은 의사-제어된 NCV-양자게이트를 이용한 가역 및 비가역 양자회로들의 함수표현과 새로운 함수합성에 유용하다.

• 한국항행학회논문지
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• 제18권5호
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• pp.483-489
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• 2014

제안된 회로는 교류 입력 전원부와 무손실 스너버 회로가 부가된 DC-DC 컨버터와 DC-AC 변환을 위한 인버터로 구성하였다. 변환된 등가회로를 이용하여 형광램프의 특성을 만족시킬 수 있는 최적의 회로상수를 결정해서 설계함으로써 기존의 인버터 직류측에서 발생되는 맥동주파수에 의한 왜형파 발생을 제거하고 인버터의 입력전류를 불연속이 되도록 하므로써 맥동율과 스위칭 손실을 현저히 감소시켰다. 이러한 모든 결과를 증명하기 위하여 40 W 직관형 형광램프를 대상으로 실험하여 고조파의 발생을 측정한 결과 제안된 전자식 안정기의 우수성을 확인하였다.

• Journal of Nutrition and Health
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• 제37권4호
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• pp.316-328
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• 2004

The objective of this study was to investigate the differences in food intake patterns by the economic status. Data from the 1998 Korean National Health and Nutrition Survey were used. Using the poverty line based on the 1998 Korean minimum cost of living, the subjects (n = 10400) were classified into high class (36.1%), middle class (40.7%) and low class (23.1%). Mean intakes for other food groups except grains, potatoes and vegetables became higher as the eco-nomic levels were going up. By the family size, it was found that intakes of grains and fishes were different (p<0.05). By the economic status, intakes of fruits (p<0.05), meats (p<0.05) and fishes (p<0.01) were different. There were no significant differences in consumed types of food by the economic status. Rice was the most prevalent food in all clas-ses and its intakes increased as the economic status was going down. In the dietary patterns of main food group (GMDVF: Grain, Meats, Dairy, Vegetable and Fruit), the pattern except dairy (11011) revealed the highest proportion in high-middle class while the patterns without dairy and fruit food groups (11010) had the highest proportion in low class. The propor-tions of subjects with the low dietary diversity score (DDS) increased as economic status was going down (p<0.01). The food groups that most people do not consume were the dairy and fruit group. Proportions of people who missed one or more group increased as economic status was going down. The high dietary variety score (DVS) also was linked to a high score on the DDS and high class (p＜0.01). Thus the intakes of the dairy and fruits product should be increased in all classes. The low class especially had worse quality of food intakes pattern than that of the high or middle class. The nutrition policy and education programs need to be established according to the economic status.

• 한국의류산업학회지
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• 제14권2호
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• pp.173-183
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• 2012

This paper intends to find out any possibility that a traditional fan can be continuously used for design development of fashion cultural products which highlight the differentiated uniqueness of Korean traditional cultures. For this purpose, this paper will newly reinterpret design-based formative factors that the shape and the line of a traditional fan shows, and then, make a pattern. This paper studied the existing literatures of a traditional fan, made the shape of a traditional fan into a motif, using computer graphic programs, like Adobe Illustrator CS 2 and Adobe Photoshop CS2, and then, applied it to neckties, T-shirts, and scarves. Among various kinds of traditional fans this paper set 4 basic motifs of new formative images by use of the shapes of Dan-Seon and Jeob-Seon, and then, developed them into two basic motifs each. Pink, blue, purple, green, yellow, orange, and gray were used as the basic colors of the motifs, through which splendid, but calm images were planned. The design of a necktie, which used a developed motif design, was applied in the form of a repeated pattern, through which a calm image was expressed. 45o turn was applied to this design to make a striped pattern image or a refined and cheerful image. The scarf design was developed into a rectangular long scarf so it can be used like a shawl. The design of T-shirt was developed into three types: a round neck-lined half-sleeved box type; a round neck-lined sleeveless type; and a V neck-lined, tight half-sleeved type.