Inhibitory Activity of Nitric Oxide Synthase and Peroxynitrite Scavenging Activity of Extracts of Perilla frutescens
![]() |
Kim, Jae-Yeon
(College of Pharmacy, Sookmyung Women's University)
Kim, Ji-Sun (College of Pharmacy, Sookmyung Women's University) Jung, Chan-Sik (Yeongnam Agricultural Research Institute, NICS, RDA) Jin, Chang-Bae (Division of Life Sciences, Korea Institute of Science & Technology (KIST)) Ryu, Jae-Ha (College of Pharmacy, Sookmyung Women's University) |
1 | Lee, J. I., Han, E. D., Lee, S. T. and Park, H. W. (1986) Study on the evaluation of oil quality and the differences of fatty acid composition between varieties in perilla (Perilla frutescens Britton var. japonica Hara ). Korean J. Breeding 18:228-233 |
2 | Park, H.-S., Ahn, B. and Yang, C.-B. (1990) Studies on the functional properties of sesame and perilla protein isolate. Korean J. Food Sci. Technol. 22: 350-356 과학기술학회마을 |
3 | Kim, T. J. (1996) Natural plant resources in Korea, Seoul National University Press |
4 | Wolfe, T. A. and Dasta, J. F. (1995) Use of nitric oxide synthase inhibitors as a novel treatment for septic shock. Ann. Pharmacother. 29: 36-46 DOI |
5 | Kooy, N. W. and Royall, J. A., Ischiropoulos, H. and Beckman, J. S. (1994) Peroxynitrite-mediated oxidation of dihydrorhodamine 123. Free Radic. Biol. Med. 16: 149-156 DOI ScienceOn |
6 | Wang, J. and Mazza, G. (2002) Inhibitory effects of anthocyanins and other phenolic compounds on nitric oxide production in LPS/IFN-gamma-activated RAW 264.7 macrophages. J. Agric. Food Chem. 50: 850-857 DOI ScienceOn |
7 | Boissel, J. P., Schwarz, P. M. and Forstermann, U. (1998) Neuronal-type NO synthase: transcript diversity and expressional regulation. Nitric Oxide 2: 337-349 DOI ScienceOn |
8 | Radi, R., Beckman, J. S., Bush, K. M. and Freeman, B. A. (1991) Peroxynitrite oxidation of sulfhydryls. The cytotoxic potential of superoxide and nitric oxide. J. Biol. Chem. 266: 4244-4250 |
9 | Meda, L., Cassatella, M. A., Szendrei, G. I., Otvos, L. Jr., Baron, P., Villalba, M., Ferrari, D. and Rossi, F. (1995) Activation of microglial cells by beta-amyloid protein and interferon-gamma. Nature 374: 647-650 DOI ScienceOn |
10 | Busse, R. and Fleming, I. (1995) Regulation and functional consequences of endothelial nitric oxide formation. Ann. Med. 27: 331-340 DOI |
11 |
Green, L. C., Wagner, D. A., Glogowski, J., Skipper, P. L., Wishnok, J. S. and Tannenbaum, S. R. (1982) Analysis of nitrate, nitrite, and [ |
12 | Moilanen, E. and Vapaatalo, H. (1995) Nitric oxide in inflammation and immune response. Ann. Med. 27: 359-367 DOI |
13 | Ignarro, L. J., Buga, G. M., Wood, K. S., Byrns, R. E. and Chaudhuri, G. (1987) Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide. Proc. Natl. Acad. Sci. U.S.A. 84: 9265-9269 |
14 | Hibbs, J. B. Jr., Taintor, R. R., Vavrin, Z. and Rachlin, E. M. (1988) Nitric oxide: a cytotoxic activated macrophage effector molecule. Biochem. Biophys. Res. Commun. 157: 87-94 DOI ScienceOn |
15 | Pfeilschifter, J., Eberhardt, W., Hummel, R., Kunz, D., Muhl, H., Nitsch, D., Pluss, C. and Walker, G. (1996) Therapeutic strategies for the inhibition of inducible nitric oxide synthasepotential for a novel class of anti-inflammatory agents. Cell Biol. Int. 20: 51-58 DOI ScienceOn |
16 | Lee, K.-I., Rhee, S.-H., Kim, J.-O., Chung, H.-Y. and Park, K.-Y. (1993) Antimutagenic and antioxidative effects of perilla leaf extracts. J. Korean Soc. Food. Nutr. 22: 175-180 과학기술학회마을 |
17 | McCartney-Francis, N., Allen, J. B., Mizel, D. E., Albina, J. E., Xie, Q. W., Nathan, C. F. and Wahl, S. M. (1993) Suppression of arthritis by an inhibitor of nitric oxide synthase. J. Exp. Med. 178: 749-754 DOI ScienceOn |
18 | Sakai, T. and Hirose, Y. (1969) Farnesenes isolated from the volatile oil of Perilla frutescens f. viridis Makino. Bull. Chem. Soc. Jpn. 42: 3615 DOI ScienceOn |
19 | Han, H.S., Park, J.H., Choe, H.J., Son, J.H., Kim, Y.H., Kim, S. and Choe, C. (2004) Biochemical analysis and physiological activity of perilla leaves. Korean J. Food Culture 19:94-105 |
20 | Haenen, G. R., Paquay, J. B., Korthouwer, R. E. and Bast, A. (1997) Peroxynitrite scavenging by flavonoids. Biochem. Biophys. Res. Commun. 236: 591-593 DOI ScienceOn |
21 | Salvemini, D., Misko, T. P., Masferrer, J. L., Seibert, K., Currie, M. G. and Needleman, P. (1993) Nitric oxide activates cyclooxygenase enzymes. Proc. Natl. Acad. Sci. U.S.A. 90:7240-7244 |
22 | Yamazaki, M. and Saito, K. (2006) Isolation and characterization of anthocyanin 5-O-glucosyltransferase in Perilla frutescens var. crispa by differential display. Methods Mol. Biol. 317: 255-266 |
23 | Park, K.-Y., Lee, K.-I. and Rhee, S.-H. (1992) Inhibitory effect of green-yellow vegetables on the mutagenicity in salmonella assay system and on the growth of AZ -521 human gastric cancer cells. J. Korean Soc. Food Nutr. 21: 149-153 과학기술학회마을 |
24 | Gehrmann, J., Matsumoto, Y. and Kreutzberg, G. W. (1995) Microglia: intrinsic immuneffector cell of the brain. Brain Res. Brain Res. Rev. 20: 269-287 DOI ScienceOn |
25 | Choung, M. G. (2005) Comparison of major characteristics between seed perilla and vegetable perilla. Korean J. Crop Sci. 50: 171-174 과학기술학회마을 |
26 | Angus, J. A. and Cocks, T. M. (1989) Endothelium-derived relaxing factor. Pharmacol. Ther. 41: 303-352 DOI ScienceOn |
27 | McGeer, P. L. and McGeer, E. G. (1995) The inflammatory response system of brain: implications for therapy of Alzheimer and other neurodegenerative diseases. Brain Res. Brain Res. Rev. 21: 195-218 DOI ScienceOn |
28 | Szabo, C. (1996) The pathophysiological role of peroxynitrite in shock, inflammation, and ischemia-reperfusion injury. Shock 6: 79-88 DOI ScienceOn |
29 | 농작물 직무육성 신품종선정위원회 결과 보고서 (2001) 351-354, 농촌진흥청 |
30 | Nagatsu, A., Tenmaru, K., Matsuura, H., Murakami, N., Kobayashi, T., Okuyama, H. and Sakakibara, J. (1995) Novel antioxidants from roasted perilla seed. Chem. Pharm. Bull. (Tokyo) 43: 887-889 DOI ScienceOn |
![]() |