• 센서학회지
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• 제28권2호
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• pp.113-116
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• 2019

A three-dimensional porous structure was fabricated by pattern transfer printing for applications of electrodes in gas sensors. To form replica patterns, solutions were mixed with acetone, toluene, heptane, and poly(methyl methacrylate). These replica patterns can also be formed on substrates such as polyimide, polydimethylsiloxane, and silicon. The wide range of line widths from 1 to $5{\mu}m$ was derived from the surface grating patterns of master substrates. The cross-bar pattern with 40 layers showed a thickness of 600 nm. The area of platinum transferred patterns with different line widths was enhanced to $20{\times}25mm$, which is applicable to various electrode patterns of gas sensors.

• 대한기계학회논문집B
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• 제38권10호
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• pp.817-829
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• 2014

조직공학 분야에서의 3 차원 구조체는 세포의 성장과 분화를 유도하기 위한 미세 환경을 제공하고, 재생하고자 하는 조직의 형태를 유지할 수 있도록 지탱해 주는 역할을 수행한다. 현재까지 다양한 생체재료 및 이의 가공 기법들이 이러한 3 차원 구조체를 제작하는데 적용되고 있다. 특히, 3 차원 프린팅 기술은 다양한 재료를 이용하여 원하는 외부 형상과 내부 구조를 제작할 수 있기 때문에 오늘날 조직공학 분야에 많이 이용되고 있고, 이 기술을 통해 새로운 조직공학적 접근 방법도 시도되고 있다. 본 논문에서는, 현재 조직공학 분야에 적용되고 있는 3 차원 프린팅 기술과, 이를 통해 제작된 기능성 인공지지체 및 세포 프린팅 구조체, 그리고 이의 다양한 조직공학적 적용에 대해서 서술하고자 한다.

• 한국산업보건학회지
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• 제28권3호
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• pp.241-256
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• 2018

Objectives: This study aimed to review the characteristics of three-dimensional printing technology focusing on printing types, materials, and health hazards. We discussed the methodologies for exposure assessment on hazardous substances emitted from 3D printing through article reviews. Methods: Previous researches on 3D printing technology and exposure assessment were collected through a literature review of public reports and research articles reported up to July 2018. We mainly focused on introducing the technologies, printing materials, hazardous emissions during 3D printing, and the methodologies for evaluation. Results: 3D printing technologies can be categorized by laminating type. Fused deposition modeling(FDM) is the most widely used, and most studies have conducted exposure assessment using this type. The printing materials involved were diverse, including plastic polymer, metal, resin, and more. In the FDM types, the most commonly used material was polymers, such as acrylonitrile-butadiene-styrene(ABS) and polylactic acids(PLA). These materials are operated under high-temperature conditions, so high levels of ultrafine particles(mainly nanoparticle size) and chemical compounds such as organic compounds, aldehydes, and toxic gases were identified as being emitted during 3D printing. Conclusions: Personal desktop 3D printers are widely used and expected to be constantly distributed in the future. In particular, hazardous emissions, including nano sized particles and various thermal byproducts, can be released under operation at high temperatures, so it is important to identify the health effects by emissions from 3D printing. Furthermore, appropriate control strategies should be also considered for 3D printing technology.

• Journal of International Society for Simulation Surgery
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• 제1권2호
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• pp.99-102
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• 2014

The skull defect can be made after the trauma, oncologic problems or neurosurgery. The skull reconstruction has been the challenging issue in craniofacial fields for a long time. So far the skull reconstruction with autogenous bone would be the standard. Although the autogenous bone would be the ideal one for skull reconstruction, donor site morbidity would be the inevitable problem in many cases. Meanwhile various types of allogenic and alloplastic materials have been also used. However, skull reconstruction with many alloplastic material have produced no less complications including infection, exposure, and delayed wound healing. Because the 3D printing technique evolved so fast that 3D printed titanium implant were possible recently. The aim of this trial is to try to restore the original skull anatomy as possible using the 3D printed titanium implant, based on the mirrored three dimensional CT images based on the computer simulation. Preoperative computed tomography (CT) data were processed for the patient and a rapid prototyping (RP) model was produced. At the same time, the uninjured side was mirrored and superimposed onto the traumatized side, to create a mirror-image of the RP model. And we fabricated Titanium implant to reconstruct three-dimensional orbital structure in advance, using the 3D printer. This prefabricated Titanium-implant was then inserted onto the defected skull and fixed. Three dimensional printing technique of titanium material based on the computer simulation turned out to be very successful in this patient. Individualized approach for each patient could be an ideal way to manage the traumatic patients in near future.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제43권5호
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• pp.288-298
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• 2017

Craniomaxillofacial injuries produce complex wound environments involving various tissue types and treatment strategies. In a clinical setting, care is taken to properly irrigate and stabilize the injury, while grafts are molded in an attempt to maintain physiological functionality and cosmesis. This often requires multiple surgeries and grafts leading to added discomfort, pain and financial burden. Many of these injuries can lead to disfigurement and resultant loss of system function including mastication, respiration, and articulation, and these can lead to acute and long-term psychological impact on the patient. A main causality of these issues is the lack of an ability to spatially control pre-injury morphology while maintaining shape and function. With the advent of additive manufacturing (three-dimensional printing) and its use in conjunction with biomaterial regenerative strategies and stem cell research, there is an increased potential capacity to alleviate such limitations. This review focuses on the current capabilities of additive manufacturing platforms, completed research and potential for future uses in the treatment of craniomaxillofacial injuries, with an in-depth discussion of regeneration of the periodontal complex and teeth.

• 대한치과교정학회지
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• 제45권5호
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• pp.217-225
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• 2015

Objective: Three-dimensional (3D) printing is a recent technological development that may play a significant role in orthodontic diagnosis and treatment. It can be used to fabricate skull models or study models, as well as to make replica teeth in autotransplantation or tooth impaction cases. The aim of this study was to evaluate the accuracy of fabrication of replica teeth made by two types of 3D printing technologies. Methods: Fifty extracted molar teeth were selected as samples. They were scanned to generate high-resolution 3D surface model stereolithography files. These files were converted into physical models using two types of 3D printing technologies: Fused deposition modeling (FDM) and PolyJet technology. All replica teeth were scanned and 3D images generated. Computer software compared the replica teeth to the original teeth with linear measurements, volumetric measurements, and mean deviation measurements with best-fit alignment. Paired t-tests were used to statistically analyze the measurements. Results: Most measurements of teeth formed using FDM tended to be slightly smaller, while those of the PolyJet replicas tended to be slightly larger, than those of the extracted teeth. Mean deviation measurements with best-fit alignment of FDM and PolyJet group were 0.047 mm and 0.038 mm, respectively. Although there were statistically significant differences, they were regarded as clinically insignificant. Conclusions: This study confirms that FDM and PolyJet technologies are accurate enough to be usable in orthodontic diagnosis and treatment.

• 치위생과학회지
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• 제15권2호
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• pp.196-201
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• 2015

본 연구에서는 최근 창조경제의 일환으로서 3차원 프린팅 기술의 개발이 눈에 띄게 발전함에 따라 치의학계 보철물 제작 기술에도 영향을 주고 있는 이 기술에 의해 제작된 3본 고정성 보철물의 임상적 허용 가능성을 변연 간격을 기준으로 가늠하여보고자 하였다. 3차원 프린팅 기술에 의해 제작된 보철물 평가와 관련한 연구가 부족함에 따라 본 연구 결과를 통해 해당 종사자들(치과의사, 치과위생과, 치과기공사)에게 참고자료를 제시하고자 하였다. 연구 결과들을 종합하여 보면 3차원 프린팅 기술에 의해 제작된 3본 고정성 보철물은 같은 증례를 대상으로 전통적인 제작방식에 의해 제작된 것보다 변연 간격이 우수하지 못하였다. 비록 몇몇 임상가들이 제시한 임상적 허용 수치 내에는 존재하였으나 기존의 제작 기술을 대신하기 위해서는 앞으로 많은 연구들을 통하여 기술의 발전이 이루어져야 할 것으로 생각된다.

• 대한치과기공학회지
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• 제42권4호
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• pp.355-361
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• 2020

Purpose: In this study, we added two kinds of photoinitiators (CQ and TPO) to prepare two kinds of denture base resins (Bis-GMA series and UDMA series) for three-dimensional (3D) printing to compare and analyze their mechanical and biological properties and to find the optimal composition. Methods: Control specimens were made using the mold made of polyvinyl siloxane of the same size. Light curing was performed twice for 20 seconds on both the upper and lower surfaces with LED (light emitting diode) light-curing unit (n=10). Experimental 3D printing dental resins were prepared, to which two photoinitiators were added. Digital light processing type 3D printer (EMBER, Autodesk, CA, USA) was used for 3D printing. The specimen size was 64 mm×10 mm×3.3 mm according to ISO 20795-1. The final specimens were tested for flexural strength and flexural modulus, and MTT test was performed. Furthermore, one-way analysis of variance was performed, and the post-test was analyzed by Duncan's test at α=0.05. Results: The flexural strength of both Bis-GMA+CQ (97.12±6.47 MPa) and UDMA+TPO (97.40±3.75 MPa) was significantly higher (p<0.05) in the experimental group. The flexural modulus in the experimental group of UDMA+TPO (2.56±0.06 GPa) was the highest (p<0.05). MTT test revealed that all the experimental groups showed more than 70% cell activity. Conclusion: The composition of UDMA+TPO showed excellent results in flexural strength, flexural modulus, and biocompatibility.

• 대한의용생체공학회:의공학회지
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• 제39권5호
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• pp.188-207
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• 2018

Recently, three-dimensional (3D) printing of biological tissues and organ has become an attractive interdisciplinary research topic that combines a broad range of fields including engineering, biomaterials science, cell biology, physics, and medicine. The 3D bioprinting can be used to produce complex tissue engineering scaffolds based on computer designs obtained from patient-specific anatomical data. It is a powerful tool for building structures by printing cells together with matrix materials and biochemical factors in spatially predefined positions within confined 3D structures. In the field of the 3D bioprinting, three major categories of the 3D bioprinting include the stereolithography-based, inkjet-based, and dispensing-based bioprinting. Some of them have made significant process. Each technique has its own advantages and limitations. Compared with non-biological printing, the 3D bioprinting should consider additional complexities: biocompatibility, degradability of printing materials, cell types, cell growth, cell viability, and cell proliferation factors. Numerous 3D bioprinting technologies have been proposed, and some of them have been making great progress in printing several tissues including multilayered skin, cartilaginous structures, bone, vasculature even heart and liver. This review summarizes basic principles and key aspects of some frequently utilized printing technologies, and introduces current challenges, and prospects in the 3D bioprinting.

• 한국정밀공학회지
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• 제15권9호
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• pp.50-55
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• 1998

A thermal printing head is used for heat transcription printing of facsimile or printer. The thermal printing head has multilayered thin films and heaters lined up. Thermal analysis of thermal printing head is important for a design of thermal printing head. Since the heating charateristics of thermal printing head is dependent on the thermal conductivities of multilayerd material, this study made numerical analysis for three dimensional transient heat conduction in mutilayered films by the finite difference method and investigated the effect of various thermal conductivities of thin films. The results of this study will be used to design thermal printing head and select the materials for thermal printing head.