• Journal of Oral Medicine and Pain
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• 제19권1호
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• pp.125-136
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• 1994

Observation of elastic fiber's change of mouse TMJ due to several round factor, principally external stimulations, their influence on the TMJ structure's change and the analize of the consecutive evolution of the disease in most important. So, the author believe that the factor of TMJ feature is the elastic feature's change and it's the principal factor of the TMJ disease. For observation of the increase and disposition of elastic fiber that to regulate the elastic feature of tissue and allow it existence. For this propose, observation with histologic methods on 20mouse ICR of 3 days, 1 week, 2 weeks, 3 weeks and 4 weeks. The results were as follow : 1. In the early stage, the condyle of TMJ is originated from cartilage mass, and it's calcification is endochondral. 2. In the early stage, the disc is relatively thin and immature, but in the later stage the fiber is dense and the disposition is most functional. 3. Observation of the early stage, the elastic fiber is a thin fiber that to across antero- posterior direction, but in the later stage elastic fiber are developed, the disposition that in the early stage was perpendicular to articular surface, now in parallel. 4. The elastic fiber was observated most clearly in the retrodiscal tissue. 5. In conclusion, the elastic fiber is observed like a thin fiber 1 week from born, but the fiber to increase the weight and it dispose functionally, and 4 week from born, it can realize the normal function.

• 정보처리학회논문지B
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• 제14B권3호
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• pp.153-162
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• 2007

사상의학은 우리나라의 대표적인 의학으로 사람의 체질을 4가지로 분류하고 각 체질별로 처치방법을 달리하는 독특한 의학이다. 이러한 사상체질에서 가장 중요한 것은 사상체질의 분류이며 이를 정확히 감별하는 일은 매우 어려운 과제이다. 이를 위해 본 논문에서는 체질별 분류를 행할 수 있는 하이브리드 형태의 진단기기 개발을 목표로 하고 이 중 본 논문은 용모사기론에 입각하여 이목구비에 대한 형태학적인 특징을 파악하는 방법에 대해 제안하고자 한다. 본 논문에서는 1단계에서 QSCC II 프로그램을 통해 사상체질군을 분류하고 이를 검증하였으며, 2단계에서 이목구비에 대한 실측으로 각 체질 간 이목구비 계측치를 분석하여 보다 정확하고 편리하게 체질을 분류할 수 있는 방법을 제시하고 이를 검증하였다. 또한 3단계에서는 정면 얼굴과 측면 얼굴에 대한 체질 분류 기반의 주요 영역을 추출, 분석하고 검증하였다. 이와 같은 실험, 고찰 및 검증과정을 통해 정확한 사상체질 분류 진단기기 개발을 위한 정면 얼굴과 측면 얼굴에서 안면 색상 기반의 주요 얼굴 영역을 추출하는 방법을 제안하고자 한다.

• Journal of Veterinary Science
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• 제21권1호
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• pp.16.1-16.10
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• 2020

Cancer is a major cause of death in dogs worldwide, and the incidence of cancer in dogs is increasing. The attenuated total reflection Fourier transform infrared spectroscopic (ATR-FTIR) technique is a powerful tool for the diagnosis of several diseases. This method enables samples to be examined directly without pre-preparation. In this study, we evaluated the diagnostic value of ATR-FTIR for the detection of cancer in dogs. Cancer-bearing dogs (n = 30) diagnosed by pathologists and clinically healthy dogs (n = 40) were enrolled in this study. Peripheral blood was collected for clinicopathological diagnosis. ATR-FTIR spectra were acquired, and principal component analysis was performed on the full wave number spectra (4,000-650 cm^-1). The leave-one-out cross validation technique and partial least squares regression analysis were used to predict normal and cancer spectra. Red blood cell counts, hemoglobin levels and white blood cell counts were significantly lower in cancer-bearing dogs than in clinically healthy dogs (p < 0.01, p < 0.01 and p = 0.03, respectively). ATR-FTIR spectra showed significant differences between the clinically healthy and cancer-bearing groups. This finding demonstrates that ATR-FTIR can be applied as a screening technique to distinguish between cancer-bearing dogs and healthy dogs.

• 대한치과교정학회지
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• 제22권3호
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• pp.703-713
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• 1992

Researches in pathologic entities and syndromes that describe temporomandibular joint (TMJ) or TMJ-related pain and dysfunction, have been hampered by confusion and conflict over the pathogenesis of myofascial and joint pain, the character and causes of joint noises, and the lack of scientific methods. Investigators have more recently correlated clinical diagnosis and arthrographic and surgical findings to demonstrate 'internal derangements' of the TMJ. It is thought that the structural and functional changes characteristic of internal derangements constitute the principal pathologic entity of the TMJ. Cephalometric data from a group of 34 subjects with documented functional changes in the TMJ were compared with those of a group of 35 subjects from a control sample. The results were as follows: 1. Comparison of a group which shows Class I relationship, there was a tendency to show clock-wise rotation of mandible and linguoversion of upper and lower anterior teeth in the experimental sample. 2. Excluding the vertical relationship, there was a tendency to show low values of the lingual surface slope of the upper central incisor and high values of the interincisor angle in the experimental sample.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제32권6호
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• pp.577-581
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• 2010

Descending necrotizing mediastinitis (DNM) is a complication of odontogenic or oropharyngeal infections that can spread to the mediastinum. Such infections is serious, leading to sepsis and frequently to death. Even in this era of antibiotics, the mortality rate associated with DNM is approximately 40%. It is difficult to diagnose early because clinical and radiologic findings appear in the late stage of the infection. Delayed diagnosis is the principal reason for the high mortality in DNM. Therefore, descending necrotizing mediastinitis requires an early and aggressive surgical approach to reduce the high morbidity and mortality associated with this disease. We experienced a case of odontogenic infection followed by acute mediastinitis, so present now with the review of literatures.

• Tuberculosis and Respiratory Diseases
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• 제77권4호
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• pp.161-166
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• 2014

Since tuberculosis (TB) remains a major global health concern and the incidence of multi-drug resistant (MDR)-TB is increasing globally, new modalities for the detection of TB and drug resistant TB are needed to improve TB control. The Xpert MTB/RIF test can be a valuable new tool for early detection of TB and rifampicin resistance, with a high sensitivity and specificity. Late-generation fluoroquinolones, levofloxacin, and moxifloxacin, which are the principal drugs for the treatment of MDR-TB, show equally high efficacy and safety. Systemic steroids may reduce the overall TB mortality attributable to all forms of TB across all organ systems, although inhaled corticosteroids can increase the risk of TB development. Although fixed dose combinations were expected to reduce the risk of drug resistance and increase drug compliance, a recent meta-analysis found that they might actually increase the risk of relapse and treatment failure. Regarding treatment duration, patients with cavitation and culture positivity at 2 months of TB treatment may require more than 6 months of standard treatment. New anti-TB drugs, such as linezolid, bedaquiline, and delamanid, could improve the outcomes in drug-resistant TB. Nontuberculous mycobacterial lung disease has typical clinical and immunological phenotypes. Mycobacterial genotyping may predict disease progression, and whole genome sequencing may reveal the transmission of Mycobacterium abscessus. In refractory Mycobacterium avium complex lung disease, a moxifloxacin-containing regimen was expected to improve the treatment outcome.

• 한국기계가공학회지
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• 제19권9호
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• pp.47-52
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• 2020

With the 4th industrial revolution, condition monitoring using machine learning techniques has become popular among researchers. An overload due to complex operations causes several irregularities in MOSFETs. This study investigated the acquired voltage to analyze the overcurrent effects on MOSFETs using a failure mode effect analysis (FMEA). The results indicated that the voltage pattern changes greatly when the current is beyond the threshold value. Several features were extracted from the collected voltage signals that indicate the health state of a switched-mode power supply (SMPS). Then, the data were reduced to a smaller sample space by using a principal component analysis (PCA). A robust machine learning algorithm, the support vector machine (SVM), was used to classify different health states of an SMPS, and the classification results are presented for different parameters. An SVM approach assisted by a PCA algorithm provides a strong fault diagnosis framework for an SMPS.

• 한국콘텐츠학회논문지
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• 제9권10호
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• pp.284-291
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• 2009

21세기 국가위기환경은 변화의 탬포가 빠르고 유동적이면서 국가안보위협의 유형과 주체가 다양해지고, 그 결과 위협의 진단과 대처가 과거에 비해 훨씬 큰 불확실성 속에서 이루어진다는 특징을 가지고 있다. 폭력에 의하여 인간의 고귀한 생명과 그들이 가진 재산을 송두리째 파괴하는 테러리즘은 세계화 정보화 시대의 기술발전과 맞물리면서 이 세상 거의 모든 국가나 공동체 그리고 개인이 테러리즘으로부터 안심할 수 없는 잠재적 공격대상이 되고 있다. 본 연구에서는 전통적 테러리즘의 개념과 뉴테러리즘의 특징을 살펴보고, 테러리즘의 실태를 분석함으로써, 언제든지 우리나라도 테러리즘의 대상이 될 수 있고, 국민들 역시 테러리즘의 타겟이 될 수 있다는 현실적인 상황에서 국가위기관리 차원에서 테러리즘에 대한 대비와 정책적 제언을 하고자 한다.

• 사상체질의학회지
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• 제9권1호
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• pp.25-101
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• 1997

The physiologic and pathologic theories of "The Yellow Emperor's Canon of Internal Medicine (黃帝內經)" were based on yin-yang theory. It has been an important constituent of traditional Chinese medicine, and the eight principal syndromes have been main guidelines in diagnosis and treatment. Recently it had an great influene on the formation of the pathophysiology of Constitutional medicine. Therefore each constitution menifests special pathophysiologic propriorities of the eight pricipal syndromes, especially specific to one's constitution. So we can recognize specific patterns of the yin and yang, cold and heat, exterior and interior, deficient and excessive syndromes through a series of processes distinguishing one's constitution. The theory of the Constitutional medicine, however, has contained those achievements in a new angle and view the problem from a little different standpoint. The dynamic relationships inevitably have caused certain changes and distortions in the meaning and application of eight principles. These are a progress in medical science, and this advance is the stirring venture of Lee jaema. This thesis has intended to show the delicate relationship between the two, and investigate into these "changes and distortions".

• 대한한의진단학회지
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• 제18권1호
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• pp.11-24
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• 2014

Objectives The aim of this study is to contribute to the establishment of the Traditional Korean Medicine (TKM) policies in future, which is through the assessment to predict the realization by diagnostic subjects. Methods First, we evaluated 8 subjects that were deduced by professionals in 1996 regarding whether or not to be realized in 2013. Second, the governmental and private research projects, reports, articles, domestic patents and products were reviewed and investigated. Third, the Subjects in domestic fields of TKM were investigated on the followings: importance, time of realization, domestic Research and Development level, principal agents and methods for the realization, and hindrance factor on the realization. Results Of the 8 forecasting subjects, one subject was realized, two subjects were partly realized and five subjects were unrealized. Thus, their realization rate was 12.5%. The realized subject is the 'Standard naming of the TKM diagnosis'. Conclusion Continuous researches are necessary to realize the TKM subjects and moreover, professionals should predict new feasible TKM subjects, based on this study.