• Title/Summary/Keyword: Preventive possibility

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Study of evacuation fire doors in multiple facilities (다중이용시설의 피난방화문에 관한 연구)

  • Cha, Jong-Ho
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.15 no.12
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    • pp.7380-7384
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    • 2014
  • Evacuation fire doors were manufactured by applying phosphorescent paint to the whole fire door whose performance was already recognized, and applying heat sensitive paint around the grip. The facility was improved by the evacuation and safety functions on the fire door, which has been used as only a fire facility, and the fire door is also used as an evacuation facility. The brilliance of the evacuation safety fire door manufactured in this study passed the brilliance test of Korea Fire Institute with a performance more than the brilliance (7mcd after 60 minutes) of the existing inducement sign. During a fire, the visible area is larger than the evacuation door inducement, etc. and light preventive status in the lower part of the fire door was observed during the descent of smoke. Therefore, it is considered to extend the evacuation effective time of evacuators. In heat sensitive paint applied around the grip, a color change is observed on the fire door when approaching a certain temperature ($70^{\circ}C$). Therefore, the first disaster that evacuators can encounter on the grip of a fire door during a fire can be prevented and should be helpful in recognizing the backfiring possibility and preventing safety accidents for firefighters who must enter a fire space.

Screening and Development of DNA Aptamers Specific to Several Oral Pathogens

  • Park, Jung-Pyo;Shin, Hye Joo;Park, Suk-Gyun;Oh, Hee-Kyun;Choi, Choong-Ho;Park, Hong-Ju;Kook, Min-Suk;Ohk, Seung-Ho
    • Journal of Microbiology and Biotechnology
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    • v.25 no.3
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    • pp.393-398
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    • 2015
  • Aptamers are composed of single-stranded oilgonucleotides that can selectively bind desired molecules. It has been reported that RNA or DNA could act as not only a genetic messenger but also a catalyst in metabolic pathways. RNA aptamers (average sizes 40-50 bp) are smaller than antibodies and have strong binding capacities to target molecules, similar to antigenantibody interactions. Once an aptamer was selected, it can be readily produced in large quantities at low cost. The objectives of this study are to screen and develop aptamers specific to oral pathogens such as Porphyromonas gingivalis, Treponema denticola, and Streptococcus mutans. The bacterial cell pellet was fixed with formaldehyde as a target molecule for the screening of aptamers. The SELEX method was used for the screening of aptamers and a modified western blot analysis was used to verify their specificities. Through SELEX, 40 kinds of aptamers were selected and the specificity of the aptamers to the bacterial cells was confirmed by modified western blot analysis. Through the SELEX method, 40 aptamers that specifically bind to oral pathogens were screened and isolated. The aptamers showed possibility as effective candidates for the detection agents of oral infections.

The Effect of Butanol Fraction of Polygonatum odoratum with Vitamin E on Blood Glucose Levels and Lipid Peroxidations in Streptozotocin-Induced Diabetic Rats (둥굴레(Polygonatum odoratum)분획물과 비타민 E 투여가 Streptozotocin 유발 당뇨 흰쥐의 혈당과 지질과산화에 미치는 영향)

  • 임숙자;김영신
    • Journal of Nutrition and Health
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    • v.31 no.9
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    • pp.1385-1393
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    • 1998
  • The hypoglycemic effects of butanol(BuOH) fraction of Polygonatum odoratum with vitamin E in streptozotocin(STZ)-induced diabetic rats were investigated. Sprague-Dawley rats weighing 200-230g were devided into five groups, and four groups induced diabetes mellitus by the STZ injection(45mg/kg b.w.) into the tail vein : Normal, diabetic-control, and three diabetic experimental groups(p. odoratum group, P. od-vit. E group and Vit. E group). All groups were fed on a AIN-76 diet, and the experimental groups were orally administered with the BuOH fraction of Polygonatum odoratum(500mg/kg b.w.) and vitamin E(10mg/kg b.w.) for 14 days. The body weight, diet intake and organ weights were monitored. The plasma levels of glucose, insulin, cholesterol, triglyceride, HDL-cholesterol and aspartate and alanine aminotransferase activities were analyzed. The levels of glycogen in liver and muscle, cholesterol in liver were determined. The malondialdehyde(MDA) levels in liver, kidney and lung were assayed. The body weight loss was seen in P. odoratum group, P. od-vit. E group, Vit. E group and diabetic control group, while the loss in P. odoratum group was much less than that in the diabetic control group. The plasma glucose levels were significantly lowered in P. odoratum group compared to diabetic control group. The plasma insulin levels were noticeably higher in P. odoratum and Vit. E groups. The rats in P. odoratum and P. od-vit. E group showed higher liver glycogen levels than in the diabetic control group. The MDA levels in liver, kidney and lung were also significantly reduced in P. od-vit. E and Vit. E groups compared to the diabetic control group. The results suggest that the administration of BuOH fraction of Polygonatum odoratum along with vitamin E reduced blood glucose levels and peroxidative tissue damage in STZ-induced diabetic rats, showing the possibility of preventive and therapeutic use of the wild edible plant to the diabetes mellitus. (Korean J Nutrition 31(9) : 1385-1393, 1998)

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A Study for the Fire Analysis and Igniting Cause of Freezing Protection Heating Cables (동파방지열선 화재 흔적분석과 발화원인 연구)

  • Lee, Jung Il;Ha, Kag Cheon
    • Journal of the Korean Society of Safety
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    • v.33 no.3
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    • pp.15-20
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    • 2018
  • There have been a number of major fatal fire accidents in Korea recently. The number of fires in 2017 were 44,178, which is not only increasing number of fires but also increasing in casualties. Particularly, the fire at Jecheon Sports Center, which suffered many casualties, is expected to have a huge impact. The cause of the fire has not been determined yet, but heat waves on the ceiling have also been pointed out. As such, the copper heating waves, which are used as a preventive measure against damage of pipes due to freezing of pipes, etc., always have a fire hazard. To determine the possibility of a flame-resistant heated fire, a positive electric cable product was used to artificially ignite and analyze the results. In case of a short circuit, the external covering of the positive electric cable is damaged, but not short circuit unless the heating material surrounding the wire is damaged. Due to the characteristics of heating cable for preventing copper waves, the chances of insulation becoming more severe due to moisture and temperature changes are higher than normal wires. If the internal heating system is carbonized by insulating deterioration without damage to the outer coating, it is likely to cause trekking, to form a winding loop in the heating materials, and to cause short circuit in the heated materials. For the positive temperature line, if the middle is shorted, the current continues to flow to the short circuit unless the breaker disconnects. Consequently, a heated fire that does not cut off the power immediately may leave multiple marks or cuts.

Chronic Aircraft Noise Exposure and Sustained Attention, Continuous Performance and Cognition in Children (만성 항공기 소음 노출과 아동의 지속주의력과 연속수행능력 및 인지기능)

  • Lim, Myung-Ho;Park, Young-Hyun;Lee, Woo-Chul;Paik, Ki-Chung;Kim, Hyun-Woo;Kim, Hyun-Joo;Rho, Sang-Chul;Kim, Hae-Young;Kwon, Ho-Jang
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.18 no.2
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    • pp.145-153
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    • 2007
  • Objectives: This study was focused on the influence of chronic aircraft noise exposure on children's continuous performance, intelligence and reading skill. Methods: We enrolled 586 children in 4-6th grade of 7 primary schools near air base in Korea. Continuous performance was measured using the computerized ADS program. We analyzed 477-512 children on the visual continuous performance test, auditory continuous performance test, intelligence test, and reading and the vocabulary test. Intelligence was measured using vocabulary, digit span, block design, and digit symbol tests of K-WISC-III. Results: The commission error and variability deviation of auditory continuous performance test and reading test were significantly higher among children in schools with the helicopter noise and the fighting plane noise compared to children in the low noised schools. Conclusion: There was a possibility that chronic aircraft noise exposure was associated with impairment of the school performance. The result of our study also shows chronic aircraft noise was associated with reading ability.

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Developing Prevention System of Overseas Infectious Disease Based on MERS and Zika Virus Outbreak (중동호흡기증후군과 지카바이러스의 대응사례분석을 통한 해외유입 신종감염병 예방시스템 구축 방안)

  • Kim, Ja Young;Bang, Joon Seok
    • Korean Journal of Clinical Pharmacy
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    • v.26 no.4
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    • pp.330-340
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    • 2016
  • Objective: The outbreak of Middle East Respiratory Syndrome (MERS) started in South Korea in May 2015 and the end of crisis was declared in December 2015 by Korea Centers of Disease Control and Prevention (KCDC). However, Zika virus emerged in less than 2 months following MERS and showed higher mortality than other countries. This study is to assess the current prevention system of overseas infectious diseases, based on MERS and Zika virus outbreak and to suggest effective response system for the future. Methods: We conducted two surveys on medical specialists working at tertiary general hospitals regarding the effectiveness of responding system by KCDC against MERS and Zika virus and education in individual medical institutions using 5-Likert points. Response system was examined in three different periods as initial period, spreading period, and post disease period. Results: Although medical specialists received the notifications in initial period, no practical prevention was proven to be placed in responding stage by medical facilities (averagely 3.5/5 points in total and sub-analyses). During spreading period, there were several academic seminars conducted, which were evaluated as helpful. In post disease period, all answered that there were changes on patient treatment in all medical facilities, with mainly report system and the treatment regulations in case of suspicious patients for infection. Only 49% respondents answered positive on the possibility of initial responses. For questionnaire items regarding Zika virus, all answered that there were notifications prior to the first outbreak of the infected patient. Eighty% of respondents were aware of 'the Guideline system for traveling to dangerous areas', and answered that the system was moderately effective (averagely 3.8/5 points in total). For the effectiveness of prevention measures for foreign novel disease by KCDC, the average point was 3.0 in both of total and sub-analyses. Conclusion: There is not enough response system to prevent infectious disease in medical institutional and governmental levels in Korea. It would warrant the modification of overall medical system to improve preventive measures for initial spread of such diseases.

A Study on Awareness of Organization of Public Health Center based on Educational Background and Position (학력 및 직급에 따른 보건소 조직에 관한 인식도 조사)

  • Kang, Kyung-Hee;Lee, Moo-Sik;Shim, Moon Sook;Kim, Kwang-Hwan
    • Journal of the Korea Convergence Society
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    • v.2 no.1
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    • pp.37-44
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    • 2011
  • In accordance with the analysis results on the questionnaires about the awareness of employees according to positions and educational backgrounds in a public health organization, this thesis suggests the basic data on the purpose of the efficient operation and improvement of working environment in a public health organization. Two answers of the questions that "there is a possibility for promotion in the organization" and "the unit section in organization which I work for has a well-designed structure of organization" showed respectively high points in the questionnaire. On the other hand, three questions like there is a resonable way to bind the organization up, completed mission and rewards are connected, and my salary is fit for the current mission showed high points among the questions about the awareness on the organization according to the positions.

Physicochemical and Sensory Properties of Yogurt Supplemented with Corni fructus during Storage

  • Noh, Hyo Ju;Seo, Hye Min;Lee, Jun Ho;Chang, Yoon Hyuk
    • Preventive Nutrition and Food Science
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    • v.18 no.1
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    • pp.45-49
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    • 2013
  • This study was carried out to determine a possibility of adding Corni fructus extract (CFE) into yogurt for improving the neutraceutical properties of yogurt and the effects of adding CFE (2~6%, v/v) on the physicochemical and sensory properties of the products during a 15-day storage period at $4^{\circ}C$. Incorporation of CFE into the yogurt samples resulted in a significant pH reduction and a significant increase in titratable acidity. When evaluating the color of the yogurt, the $L^*$-values were not significantly influenced by CFE supplementation; however, the $a^*$- and $b^*$-values significantly increased with the addition of CFE during storage. The power law and Casson models were applied to assess the flow behavior of CFE-added yogurt samples. The magnitudes of apparent viscosity (${\eta}_{a,100}$), consistency index (K), and yield stress (${\sigma}_{oc}$) for 4~6% CFE yogurt samples were significantly greater than those for the control, indicating that CFE can be used as a thickening agent for yogurt. The sensory test revealed that addition of CFE (2~4%) to yogurt did not significantly affect the overall scores, but the overall preference score for 6% CFE yogurt was significantly decreased. Based on the data obtained from the present study, we concluded that the concentrations (2~4%) of CFE could be used to produce a CFE-added yogurt without the significantly adverse effects on the physicochemical and sensory properties.

Effect of Mother's Education Level on Prevalence of Dental Caries among Preschool Children: Analysis of Korea National Oral Health Survey 2006 (모친의 교육수준이 아동의 치아우식증 발생에 미치는 영향: 2006 국민구강건강실태조사자료 분석결과)

  • Jung, Youn;Kim, Su-Jin;Kim, Kyung-Nam;Kang, Soo-Jin;Doh, Soon-Ja
    • Korean Journal of Health Education and Promotion
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    • v.26 no.1
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    • pp.117-128
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    • 2009
  • Objectives: The purpose of this study was to assess the effect of mothers education attainment on prevalence of dental caries among their preschool children. Methods: Data were obtained from the third 2006 Korea National Oral Health Survey. A total of 515 preschool children aged 2 to 7 years and their mothers were selected in this study. We used mother's education level as her socioeconomic position and controlled children's tooth brushing frequency, tooth brushing before bed, the frequency of eating snack, and the preventive dental visit. Whether children experienced dental caries or not and the number of decayed or filled or missing tooth surface they had were used as outcome variables. Results: The proportion of children affected with dental caries was 46.21%. The mother's education level affected children's caries significantly (p<0.05) and children whose mother attended less than high school had more possibility of having caries than children whose mother graduated from college or more (p<0.05). This effect was still significant and got larger(p<0.05), even after controlling children's dental health behavior. Conclusion: This study showed that mother's education level affected the prevalence of caries among their preschool children. In addition, this result indicated a need for more definite policy for children's dental health in lower socioeconomic class with general dental education.

Social Capital and Stage of Change for Physical Activity in a Community Sample of Adults (사회자본과 신체활동 행위변화단계)

  • Kim, Gil-Yong;Kim, Eun-Mi;Bae, Sang-Soo
    • Korean Journal of Health Education and Promotion
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    • v.26 no.1
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    • pp.63-80
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    • 2009
  • Objectives: This study identified how personal characteristics, healthy behavior and social capital might influence on physical activity of adults. Methods: This study used data from the health survey of a city of Korea. We surveyed 1,000 adults sampled by stratified sampling methods from 67,889 households. Outcome variable was the stage of physical activity which was broken into 5 categories. Sociodemographic factors, healthy behavior, self-rated health status and social capital were used as control variables. Sociodemographic factors included age, sex, educational status, economic status measured by deprivation score, residential period within survey city. Social capital was measured by Integrated Questionnaire for the Measurement of Social Capital (SC-IQ). This study used chi-square test and ordered logistic regression models to examine the associations between independent variables and physical activity. Variables were added to the regression model in three groups using a hierarchical approach. Results: Physical activity was significantly more likely to become active if they have higher educational status, healthier behavior. Among the six dimensions of SC-IQ, only "groups and networks" that is structural dimensions of social capital and "trust and solidarity" that is cognitive dimensions of social capital were significantly related to physical activity of adults. We found that a person having higher density of membership and having larger size of networks showed the high possibility of active physical activity. A person having high solidarity was significantly associated with physical activity, but general trust was inversely related to physical activity. Output dimensions of social capital did not show significant relationship to physical activity. Conclusion: We found that social capital is useful concept to explain health behaviors like physical activity. However we must consider social, cultural and political context of the study to evaluate the effect of social capital to health status and health determinants and to capture the exact meaning of relationship between them. We suggest further researches to refine the concept of social capital and to explain the relationship of social capital to diverse health determinants.