• Journal of Preventive Medicine and Public Health
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• v.48 no.5
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• pp.225-230
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• 2015

Objectives: The epidemiological characteristics of breast cancer incidence by age group in Korean women are unique. This systematic review aimed to investigate the association between hormone replacement therapy (HRT) and breast cancer risk in Korean women. Methods: We searched electronic databases such as KoreaMed, KMbase, KISS, and RISS4U as well as PubMed for publications on Korean breast cancer patients. We also conducted manual searching based on references and citations in potential papers. All of the analytically epidemiologic studies that obtained individual data on HRT exposure and breast cancer occurrence in Korean women were selected. We restricted the inclusion of case-control studies to those that included age-matched controls. Estimates of summary odds ratio (SOR) with 95% confidence intervals (CIs) were calculated using random effect models. Results: One cohort and five case-control studies were finally selected. Based on the heterogeneity that existed among the six studies (I-squared=70.2%), a random effect model was applied. The summary effect size of HRT history from the six articles indicated no statistical significance in breast cancer risk (SOR, 0.983; 95% CI, 0.620 to 1.556). Conclusions: These facts support no significant effect of HRT history in the risk of breast cancer in Korean women. It is necessary to conduct a pooled analysis.

• Journal of Preventive Medicine and Public Health
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• v.48 no.6
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• pp.280-286
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• 2015

Objectives: Approximately 10% to 15% of lung cancer cases occur in never-smokers. Hormonal factors have been suggested to lead to an elevated risk of lung cancer in women. This systematic review (SR) aimed to investigate the association between hormonal replacement therapy (HRT) and the risk of lung cancer in women using cohort studies. Methods: We first obtained previous SR articles on this topic. Based on these studies we made a list of refereed, cited, and related articles using the PubMed and Scopus databases. All cohort studies that evaluated the relative risk of HRT exposure on lung cancer occurrence in women were selected. Estimate of summary effect size (sES) with 95% confidence intervals (CIs) were calculated. Results: A total of 14 cohort studies were finally selected. A random effect model was applied due to heterogeneity (I-squared, 64.3%). The sES of the 14 articles evaluating the impact of HRT exposure on lung cancer occurrence in women indicated no statistically significant increase in lung cancer risk (sES, 0.99; 95% CI, 0.90 to 1.09). Conclusions: These results showed that HRT history had no effect on the risk of lung cancer in women, even though the sES of case-control studies described in previous SR articles indicated that HRT had a protective effect against lung cancer. It is necessary to conduct a pooled analysis of cohort studies.

• Journal of Korean Society for Quality Management
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• v.20 no.1
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• pp.59-67
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• 1992

This paper deals with preventive replacements models for the item whose failures are dependent on their wear level. When measuring the item wear level is very costly, it may be economical to use substitutive characteristics that are correlated with the item wear level and relatively inexpensive to measure. In this paper, replacement policies based on such substitutive characteristics are proposed. The optimal level of substitutive characteristic to replace the item, which minimizes total cost, is obtained. Some numerical examples are also given.

• 대한예방의학회:학술대회논문집
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• 2005.10a
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• pp.352-352
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• 2005

• Journal of Korean Institute of Industrial Engineers
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• v.4 no.1
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• pp.1-3
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• 1978

This paper presents a model for determining the optimal number of minimal repairs before replacement. The basic concept parallels the periodic replacement model with minimal repair at failure introduced by Barlow and Hunter, only difference being the replacement signalled by the number of previous minimal repairs performed on the unit. In the case of Weibull distribution, which is widely used as a general failure distribution, the optimal solution could be obtained numerically and seems more cost effective compared to the Barlow and Hunter's Policy II.

• Journal of Korean Society for Quality Management
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• v.21 no.2
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• pp.109-120
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• 1993

Most systems are composed of components which have different failure chracteristics. Since the failure characteristics of components is different, it is rational and reasonable to establish a maintenance model to be considered repair and replacement policies which are proper to failure characteristics of these components. This paper proposes the age replacement time for a system composed of components which have different failure characteristics. In this model, it is assumed that a system is composed of a critical failure component, a major failure component, minor failure component. If any failure occurs to critical component before its age replacement time, the system should be replaced. If any failure does not occur until its age replacement time, preventive replacement should be performed at age replacement time T. Major component is minimal repaired if any failure occurs during operation. Minor component should be replaced as soon as failure is found. This paper determines the optimal replacement time of the system which minimize, total maintenance cost and initial stock Quantity of minor component within this optimal replacement time. Numerical example illustrates these results.

• Journal of Korean Institute of Industrial Engineers
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• v.33 no.1
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• pp.70-75
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• 2007

This paper discusses condition based preventive replacement for deteriorating systems. The system continuouslydeteriorates in time and fails at any deterioration level which is always monitored, It is replaced at failure or atsome deteriorated level preventively before failure. The deterioration process is represented by a Weibulldistribution with a time-linear scale parameter. The cost rate function is formed considering replacement costand opportunity loss cost and deterioration dependent failure distribution, If the system has an increasingdeterioration dependent failure rate, the optimal deterioration level for preventive replacement can be determinedfrom minimizing the cost rate. An illustrative example is given for a Weibull deterioration dependent failuredistribution.

• IE interfaces
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• v.16 no.1
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• pp.27-33
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• 2003

The maintenance cost in K Steelworks has been continuously increased in proportion to the production cost. However, there seems to be a possibility of reducing cost through the optimization of maintenance actions. The failure types of the equipment in steelworks ate various with different failure cost. Thus the failure rate and cost of each type of failures should be considered simultaneously when the optimum maintenance period is to be determined. It is considered that the equipment undergoes periodic replacement and a specified number of incomplete preventive maintenance actions are performed during a replacement period. Assuming that the time to failure follows a Weibull distribution, the parameters of the failure rate are estimated using the maximum likelihood estimation. The optimal replacement period is determined to minimize the average cost per unit time. As the result of analysis it is suggested that the existing maintenance period for a hot-rolling equipment can be extended significantly.

• Journal of Korean Institute of Industrial Engineers
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• v.21 no.4
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• pp.555-570
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• 1995

We consider a preventive replacement policy for a cold-standby system with N components, in which only one component is in operation at a time. If the component in operation fails, a standby component is immediately switched into operation. If all components fail, the system fails. The system is inspected at random poins in time to determine whether it is to be replaced or not. If the number of failed components at the time of inspection exceeds a threshold value r, the system is replaced. Otherwise the decision is put off until the next inspection point arrives. Under the cost structure which includes a replacement cost, a system down-time cost and a holding cost of the components, we develop an efficient procedure to find the optimal control values N and r, which minimize the expected cost per unit time.

• Proceedings of the Safety Management and Science Conference
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• 2004.11a
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• pp.115-123
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• 2004

Replacement problems can be classed as either deterministic of stochastic. Deterministic problems are those in which the timing and the outcome of the replacement action are assumed to be known with certainty. Before proceeding with development of replacement models it is important to note that preventive replacement actions, that is, ones taken before equipment reaches a failed state, require two necessary conditions: (1) The total cost of the replacement must be greater after failure than before. (2) The failure rate of the equipment must be increasing. Equipment is subject to failure. On failure, one of two possible actions can be taken : repair or complete replacement of the failed equipment. In this paper, we proposed optimal overhaul, repair, replacement maintenance model with two-state.