• 제목/요약/키워드: Pressure support

검색결과 1,108건 처리시간 0.028초

전침자극이 자연 발증 고혈압 흰쥐의 혈압 조절 중추에서 iNOS의 발현에 미치는 영향 (Effects of electroacupuncture on the expression of iNOS in Nuclei of solitary tract and Rostral ventrolateral medulla in spontaneously hypertensive rats)

  • 황혜숙;김유성;이지은;한경주;최선미;구성태
    • 한국한의학연구원논문집
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    • 제12권3호통권18호
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    • pp.59-67
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    • 2006
  • Aims: Acupuncture has been used for the treatment of essential hypertension, but the efficacy and the mechanism of acupuncture in prevention of hypertension are still unclear. We tested the hypothesis that electroacupuncture (EA) applied to Baekhoe (GV20) changes NO/NOS system during development of hypertension in spontaneously hypertensive rats (SHR), and thereby causes the delay of development of hypertension in SHR. Methods: The male SHR rats in the developmental stages of hypertension (7-8 weeks) were randomly divided into three groups (control group, GV20 acupuncture group, and tail acupuncture group). And the age matched Wistar Koyto Rats (WKY) were randomly divided into two groups (nagative control, GV20 acupuncture group). EA treatments (10Hz, 1mA, 0.1ms) were carried out for 25 min/day for five consecutive days. The systolic blood pressure (SBP) was determined in conscious rats by the tail-cuff method using automatic BP mornitoring system. We investigated the activations of inducible NO synthase (iNOS) in nuclei of solitary tract (NTS) and rostral ventrolateral medulla (RVLM) of SHR by the western blotting method. Results: The SBP after the termination of EA stimulation applied to the GV20 was stabilized at $169.14{\pm}3.67$ mmHg which is lower value than that of the control group. The SBP of control group was elevated to $178.14{\pm}3.49$ mmHg. In addition, we evaluated NOS activity as well as iNOS protein expression of NTS and RVLM in both of SHR and WKY. The iNOS activity in NTS was significantly higher in SHR than in WKY. Furthermore, the iNOS activity of NTS showed significant decreases in EA groups compare to that of non treated SHR group. Although iNOS expression of RVLM showed non significant changes between SHR and WKY, EA significantly enhanced the iNOS expression in SHR. Our data support the hypothesis that delayed development of hypertension and altered iNOS expression of NTS and RVLM by EA stimulations in SHR rats. Conclusions: The findings demonstrate that acupuncture can change NO/NOS system in NTS and RVLM, and exert beneficial role on development of hypertension.

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Research on Liquefaction Characteristics of SF6 Substitute Gases

  • Yuan, Zhikang;Tu, Youping;Wang, Cong;Qin, Sichen;Chen, Geng
    • Journal of Electrical Engineering and Technology
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    • 제13권6호
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    • pp.2545-2552
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    • 2018
  • $SF_6$ has been widely used in high voltage power equipment, such as gas insulated switchgear (GIS) and gas insulated transmission line (GIL), because of its excellent insulation and arc extinguishing performance. However, $SF_6$ faces two environmental problems: greenhouse effect and high liquefaction temperature. Therefore, to find the $SF_6$ substitute gases has become a research hotspot in recent years. In this paper, the liquefaction characteristics of $SF_6$ substitute gases were studied. Peng-Robinson equation of state with the van der Waals mixing rule (PR-vdW model) was used to calculate the dew point temperature of the binary gas mixtures, with $SF_6$, $C_3F_8$, $c-C_4F_8$, $CF_3I$ or $C_4F_7N$ as the insulating gas and $N_2$ or $CO_2$ as the buffer gas. The sequence of the dew point temperatures of the binary gas mixtures under the same pressure and composition ratio was obtained. $SF_6/N_2$ < $SF_6/CO_2$ < $C_3F_8/N_2$ < $C_3F_8/CO_2$ < $CF_3I/N_2$ < $CF_3I/CO_2$ < $c-C_4F_8/N_2$ < $C_4F_7N/N_2$ < $c-C_4F_8/CO_2$ < $C_4F_7N/CO_2$. $SF_6/N_2$ gas mixture showed the best temperature adaptability and $C_4F_7N/CO_2$ gas mixture showed the worst temperature adaptability. Furthermore, the dew point temperatures of the $SF_6$ substitute gases at different pressures and the upper limits of the insulating gas mole fraction at $-30^{\circ}C$, $-20^{\circ}C$ and $-10^{\circ}C$ were obtained. The results would supply sufficient data support for GIS/GIL operators and researchers.

자기포화 와전류기법에 의한 자성 튜브 비파괴검사 (Nondestructive Examination of Ferromagnetic Tube Using Magnetic Saturation Eddy Current Technique)

  • 이희종;조찬희;송석윤;지동현;정지홍
    • 비파괴검사학회지
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    • 제28권5호
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    • pp.407-415
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    • 2008
  • 원전 발전소 터빈계통을 구성하는 열교환기 튜브는 일반적으로 구리합금, 스테인리스강, 탄소강, 티타늄합금 등의 재질로 제작된다. 이들 재질중에서 페라이트계 type-439 스테인리스강은 자성 재질로서 오스테나이트계보다 더 높은 열전달율 가지며, 부식에 의해 유발되는 결함에 대해 더 높은 저항성을 가진다. 페라이트계 스테인리스강은 보통 발전소 열교환기의 저압급수가열기와 습분분리재열기에 사용된다. 저압급수가열기는 일반적으로 두께가 얇은 type-439 스테인리스강을 이용하는 반면에 습분분리재열기는 더 두꺼운 핀튜브를 사용한다. 이와 같이 터빈 습분분리재열기 튜브로 사용되는 type-439 스테인리스강 핀튜브는 터빈계통의 운전으로 인하여 손상이 발생할 수 있다. 손상에 의한 가장 대표적인 결함은 진동에 의해 발생할 수 있는 마모, 피로균열 등이며 마모성 결함은 일반적으로 튜브-튜브지지판에서 발생되는 것으로 보고되고 있다. 본 연구에서는 type-439 스테인리스강 자성체 튜브에 발생할 수 있는 결함을 검출하고 크기를 측정할 수 있는 자기포화 와전류탐상검사 기법의 능력을 평가하였다.

미숙아 동맥관 개존증의 외과적 교정에 관한 임상적 고찰 (Clinical Considerations of the Surgical Closure of the PDA in the Premature Infants)

  • 김상익;박철현;현성열;김정철;권진형;박국양
    • Journal of Chest Surgery
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    • 제32권8호
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    • pp.702-708
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    • 1999
  • 배경: 미숙아 동맥관 개존증의 약물적 치료로 Indomethacin을 사용하는데 이때 발생하는 합병증, 부적응증, 또는 동맥관이 다시 열릴 경우 외과적으로 교정함으로써 수술에 따른 위험성 및 합병증이 적고 지속적인 동 맥관 폐쇄가 가능하다. 대상 및 방법: 1996년 4월부터 1998년 8월까지 동맥관 개존증을 동반한 미숙아중 수 술 당시의 체중이 1.5 kg 이하인 11명의 환아(남아: 5, 여아: 6)를 대상으로 하였다. 술전 동반질환으로 선천 성 심질환(7), 유리질막증(6), 폐렴(4), 뇌실내 출혈(4), 기흉(3), 고빌리루빈혈증(2), 괴사성 장염(2), 신부전증 (1), 간질(1), 수두증(1) 등이 있었다. 사용된 외과적 술식은 헤모클립을 사용한 경우(8)와 동맥관을 결찰한 경 우(3)가 있었다. 동맥관의 크기는 3~6 mm(5.0$\pm$1.2)였다. 결과: 동맥관을 폐쇄한후 수축기 및 확장기 혈압이 상승하였고 심박동수는 감소하였다. 동맥혈 개스 결과도 호전되었다. 수술과 관련된 합병증은 없었다. 술후 6명의 환아에서 호흡기 증상의 호전과 함께 인공호흡기이탈이 가능했고 모두 외래 추적 관찰중이다(3개월~ 12개월). 술후 5명의 환아가 사망하였는데 사망 원인은 유리질막증(2례), 기관지폐 이형성증과 폐렴(1례), 패 혈증(1례), 심부전증과 특발성 호흡곤란증(1례)이었다. 결론: Indomethacin에 부적응증 혹은 합병증이 있거나, Indomethacin용법에 효과가 없거나 또는 혈역학적으로 의미있는 단락을 동반하는 미숙아 동맥관의 우선 치료 법은 조기 외과적 교정술이다.

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암 병동 간호사의 보완대체요법에 관한 인식 조사연구 (A Study on the Perception of the Nurses in Cancer Wards of the Complementary and Alternative Therapies)

  • 이정란
    • 종양간호연구
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    • 제4권2호
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    • pp.124-134
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    • 2004
  • The major results of this study were as follows : 1. The percentage of nurses who know the complementary and alternative therapies was 50.1% Most of them(70.6%) acknowledged the therapies from newspapers, television and magazines. 2. The complementary and alternative therapy was perceived as effective by 64.9% of the nurses and as trusted by 60.2% of them The effective methods of the therapy are acupuncture herb medicine and massage. 3. Most of the nurses 93.4% experienced getting inquiries from patients or their guardians whether to use the therapies. 4. The complementary and alternative therapies was experienced by 38.9% of nurses and 7.1% of them use the therapies frequently 92.9% of patients and families were satisfied with the result 'Massage Therapy' was used the most with no side-effects and thus higher need of education for nurses. 5. They wanted to be trained for massage therapy finger-pressure, music therapy, acupuncture, aroma therapy in order. 6. Reliance on the complementary and alternative therapies, 75.2% of nurses completed the course trusted the therapies and the result of others uncompleted was similar as 52.2% Moreover both 79.5% of nurses completed it and 61.6% of the others said that the complementary and alternative therapy's nursing interventions is possible to develop. 7. It shows high relation to recognition having possibilities for applying and developing as the nursing intervention. if the confidence is as high as about the complementary and alternative therapies. Based of the results of this study as above this study proposes as follows. First, The nurses should understand mentality of the patients so that the nurses have to put in operation appropriate nursing intervention as accurate knowledge of the alternation therapies using to cancer patients for having on damages to patients from their rash using way. Furthermore, it is necessary to supply the special place and the professional nurses taking complete charge at them. Next politic interest and support from government are required to develop and practice systematic and resonable education programs for the complementary and alternative therapies. Moreover, it is necessary for nurses to be educated about the therapies continually. Finally, it is compulsory that the research and development for complementary and alternative therapies is needed. In addition, it has to be made standard and legal equipment for safety efficacy and theory about the therapies.

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프랜차이즈 조직의 학습지향성과 관계마케팅지향성이 직무만족에 미치는 영향 (The Effects of Franchise's Learning Orientation and Relationship Marketing Orientation on the Job Satisfaction)

  • 황윤용;서창선;최수아
    • 유통과학연구
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    • 제11권6호
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    • pp.51-58
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    • 2013
  • Purpose - Nowadays, more than ever before, fierce competition, deep market segmentation, short product life cycles, and intensifying customer needs are putting increasing pressure on franchise's organizations to satisfy their customers by creating market-oriented relationships with and enhancing their market knowledge of them. One way that this might be achieved is by establishing deep ties (i.e., job commitment and job satisfaction) with their employees. Therefore, the purpose of this study is to examine how two important constructs of franchises' strategic efforts, LO (learning orientation) and RMO (relationship marketing orientation), affect job satisfaction, given the mediating role of job commitment. A franchise system comprises a set of contractual arrangements by which mutual obligations are performed. An organizational learning goal motivates employees to improve their abilities and master the tasks they perform. Relationship marketing, in addition, is to identify, establish, maintain, and enhance relationships with customers and other stakeholders to ensure that the objectives of all parties are met and this is done through the mutual exchange of promises. In a relationship marketing orientation, then, a firm creates, maintains, and enhances a strong relationship with its customers by sustaining long-term ties. This study was designed to examine the evolution of various theoretical approaches to franchise systems in order to determine whether theories about firms have significantly affected the franchise system. To this end, the authors developed a structural model consisting of several constructs. Previous studies have suggested that franchises' learning and relationship marketing orientations are important occupational immersion dimensions driving job satisfaction. Research design, data, methodology - We empirically tested a process of how the learning orientation and the relationship marketing orientation influence job commitment and job satisfaction using survey data drawn from 150 responding franchisees who were interviewed about their individual tendencies. Results - The results of this study provide empirical evidence that learning orientation, relationship marketing orientation, and job commitment all influence franchisees' job satisfaction. The results of this study indicate that, first, learning orientation had a significant effect on job satisfaction; second, relationship marketing orientation was positively related to job commitment; third, job commitment had a significant effect on job satisfaction. We also found that relationship marketing orientation and job satisfaction were mediated by job commitment. Conclusions - The findings of this study confirm the importance of learning orientation and relationship marketing orientation in maintaining a positive marketing relationship between franchiser and franchisee from to the perspective of the market. This indicates that franchiser support such as educational programs provided by the franchiser will help franchisees attain higher business management achievement and satisfaction. Moreover, a positive relationship between franchisees and consumers can be maintained through tie effects. Our findings also suggest that learning orientation plays a critical role in job satisfaction within the franchise system.

척수 손상자의 사회 적응에 관한 연구 (A Study on the Social Adaptation of Spinal Cord Injured Patients)

  • 이동순;송인영
    • 대한물리치료과학회지
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    • 제4권2호
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    • pp.405-419
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    • 1997
  • This research has been conducted to provide the spinal cord injured patients with comprehensive necessity of and backup data for their rehabilitation in the community and make the aware of importance of overall community support to patients. The data was collected through questionnaire made to 83 patients charged to general hospital in Jeonbuk Province between 1 and 31 March 1997 to analyse the patients ability on activities of daily living through the research on general characteristics and Modified Barthel Index(MBI). As a result the outcome of the research was as follows : 1. Sexual distribution represented that 57 male (68.7%) and 26 female(31.3%) and in the age distribution majority group was 36 thirties (43.4 %) most active in social activities. 2. Analysis on occupation of patients showed majority group was in technicians, 21 people representing 25.4 % and the major cause of injury was traffic accident, 45people representing 54.2%, fall down, 17 people representing 20.5% and industrial accident, 13 people representing 15.7%, respectively. 3. In the multiple choice questionnaire on complications, the rate of appealing pain was highest and spasticity, pressure sore, contracture, depression which restrict the patients from activities of daily living ability were also appeared. 4. The theoretical points in MBI Should lie between 1 and 115 and the average point be 58 but the average point of the MBI among 83 patients was 63. 5. The MBI point by the level of injured represented statistically critical difference(P<0.001) and the MBI points tested by Duncan's Multiple Area Testing in lumbar(80.1) and in thoracic (65.8) represented critically higher than the one in cervical(42.5). 6. In the distribution of the method of Urination after spine injury, the intermittent catheterization represented highest numbar of 34(41.1 %). Testing by Duncan's Multiple Area Testing, as we found the critical difference in the analysis on MBI points(P<0.001), the point in independent self voiding patients ($90.87{\pm}29.34$) was higher than the one in other self voiding patients(P<0.05). 7. In th category of social activities after spine injury, the number of people classified in others, 41 people representing 49.5% was highest and in the MBI points of the spinal cord injured people in religious activity, hobby activity, private club, occupation was critically higher than the people classified in miscellancous(P<0.01) who are the spinal cord injured people and mostly depend on their family's assistance at home in their daily activities.

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콜센터 상담원의 감정소진이 고객지향성 및 직무만족에 미치는 영향 (Impact of the Customer Orientation and Job Satisfaction as a Result of the Consultant's Emotional Exhaustion at the Call Center)

  • 조상은;양해술
    • 한국콘텐츠학회논문지
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    • 제10권6호
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    • pp.386-403
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    • 2010
  • 본 연구는 콜센터에서 업무특성상 감정노동(emotional labor)을 수행하는 상담원들이 감정소진(emotional exhaustion)의 결과로 고객에 대한 친절의 욕구, 성취감의 욕구 저하가 초래되어 고객지향성 및 직무만족에 영향을 주는 요인에 대하여 연구하였다. 콜센터 상담원의 감정소진이 고객지향성 및 직무만족에 어떠한 영향을 미치는지를 살펴보고자 연구모형과 가설을 설정하였다. 가설검증을 위해 서울지역 콜센터 상담원을 대상으로 회수된 설문지 157부를 실증분석에 이용하였다. 본 연구에서는 해당 상담원의 감정소진이 고객지향성 및 직무만족에 부정적인 영향을 미치는 것으로 검증되었다. 상담원의 감정소진의 정도를 줄이기 위해서는 업무수행시 시간적 압력을 낮추고 업무의 자율성과 권한을 부여하여야 하며, 유관부서의 적극적인 지원과 관리자들과 상담원간의 지속적인 커뮤니케이션을 통하여 감정소진을 저하 시키는 요인을 제거하고 개선시켜서 업무수행의 주체인 상담원의 감정소진 경험을 최소화 시켜야 한다는 중요성을 본 연구에서 제시하였다. 본 연구는 콜센터 운영에 있어서 상담원의 감정소진이 고객지향성 및 직무만족에 부정적인 영향 요소라는 것을 제시하였다는 데 의의 가 있다.

시스템-온-칩의 하드웨어-소프트웨어 통합 시뮬레이션을 위한 다목적 설계 프레임워크 (A Multipurpose Design Framework for Hardware-Software Cosimulation of System-on-Chip)

  • 주영표;윤덕용;김성찬;하순회
    • 한국정보과학회논문지:시스템및이론
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    • 제35권9_10호
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    • pp.485-496
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    • 2008
  • SoC(System-on-Chip)를 설계함에 있어서 칩의 복잡도 증가로 인하여, RTL(Register Transfer Level)에 기반한 기존의 시스템 성능 분석 및 검증 기법만으로는 점차 짧아지는 '시장 적기 출하(time-to-market)' 요구에 효율적으로 대응할 수 없게 되었다. 이를 극복하기 위하여 설계 포기 단계부터 지속적으로 시스템을 검증하기 위한 새로운 설계 방법이 요구되었으며, TLM(Transaction Level Modeling) 추상화 수준을 가진 하드웨어-소프트웨어(HW-SW) 통합 시뮬레이션이 이러한 문제를 해결하기 위한 방법으로 널리 연구되고 있다. 그러나 대부분의 HW-SW 통합 시뮬레이터들은 다양한 추상화 수준 중 일부만을 지원하고 있으며, 서로 다른 추상화 수준을 지원하는 툴들 간의 연계도 쉽지 않다. 이를 극복하기 위하여 본 논문에서는 HW-SW 통합 시뮬레이션을 위한 다목적 선계 프레임워크를 제안한다. 제안하는 프레임워크는 소프트웨어 응용의 설계를 포함하는 체계적인 SoC 설계 플로우를 제공하며, 각 설계 단계에서 다양한 기법들을 유연하게 적용할 수 있는 동시에, 다양한 HW-SW 통합 시뮬레이터들을 지원한다. 또한 플랫폼을 추상화 수준과 모델링 언어에 독립적으로 설계할 수 있어, 다양한 수준의 시뮬레이션 모델 생성이 가능하다. 본 논문에서는 실험을 통하여, 제안하는 프레임워크가 ARM9 기반의 강용 SoC 플랫폼을 정확하게 모델링 할 수 있는 동시에, MJPEG 예제의 성능을 44%까지 향상시키는 성능 최적화를 수행할 수 있음을 검증하였다.

건강기능식품의 기능성을 중심으로 한 오메가-3 지방산 함유유지의혈행개선 효과에 대한 체계적 고찰 (Systematic review of the effect of omega-3 fatty acids on improvement of blood flow while focused on evaluation of claims for health functional food)

  • 정세원;김지연;백주은;김주희;곽진숙;권오란
    • Journal of Nutrition and Health
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    • 제46권3호
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    • pp.226-238
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    • 2013
  • Omega-3 polyunsaturated fatty acids are essential fatty acids because humans cannot synthesize them de novo and must obtain them in their diet. Fish and fish oil are rich sources of omega-3 fatty acids, including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Significant evidence of the beneficial role of dietary intake of omega-3 fatty acids in blood flow has been reported and putative mechanisms for improvement of blood flow include anti-thrombotic effects, lowered blood pressure, improved endothelial function, and anti-atherogenic effects. Edible oils containing omega-3 fatty acids were registered as functional ingredients in the Korea Health Functional Food Code. Although omega-3 fatty acids have been evaluated by the Korea Food and Drug Administration (KFDA) based on scientific evidence, periodic re-evaluation may be needed because emerging data related to omega-3 fatty acids have accumulated. Therefore, in this study, we re-evaluated scientific evidence for the effect of omega-3 fatty acids as a functional ingredient in health functional food on improvement of blood flow. A comprehensive literature search was conducted for collection of relevant human studies using the Medline and Cochrane, KISS, and IBIDS databases for the years 1955-2012. Search keywords were used by combination of terms related to omega-3 fatty acids and blood flow. The search was limited to human studies published in Korean, English, and Japanese. Using the KFDA's evidence based evaluation system for scientific evaluation of health claims, 112 human studies were identified and reviewed in order to evaluate the strength of the evidence supporting a relation between omega-3 fatty acids and blood flow. Among 112 studies, significant effects on improvement of blood flow were reported in 84 studies and the daily intake amount was ranged from 0.1 to 15 g. According to this methodology of systematic review, we concluded that there was possible evidence to support a relation between omega-3 fatty acid intake and blood flow. However, because inconsistent results have recently been reported, future studies should be monitored.