• Journal of Mechanical Science and Technology
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• v.18 no.2
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• pp.253-261
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• 2004

A simple and effective filtering method to control the member size of an optimized structure is proposed for topology optimization. In the present approach, the original objective sensitivities are replaced with their relative values evaluated within a filtering area. By adjusting the size of the filtering area, the member size of an optimized structure or the level of its topological complexity can be controlled even within a given finite element mesh. In contrast to the checkerboard-free filter, the present filter focuses on high-frequency components of the sensitivities. Since the present filtering method does not add a penalty term to the objective function nor require additional constraints, it is not only efficient but also simple to implement. Mean compliance minimization and eigenfrequency maximization problems are considered to verify the effectiveness of the present approach.

• Journal of Pharmacopuncture
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• v.22 no.4
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• pp.248-252
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• 2019

Objectives: The aim of the present work is evaluating the special effects of Urtica Dioica and Lamium Album on the serum level of K-Ras and GSK-3 beta in diabetic rats. Methods: In the present experimental study, 32 male Wistar rats randomly divided into 4 groups (Group I: normal control rats; receiving daily PBS, Group 2: diabetic control rats; receiving single dose of streptozotocin (60 mg/kg) and daily PBS, Group 3: Diabetic rats treated with 100 mg/kg of hydroalcoholic extract of the U. dioica, Group 4: Diabetic rats treated with 100 mg/kg of hydroalcoholic extract of L. Album. Diabetes-induced by an intraperitoneal injection of streptozotocin (60 mg/ kg). On the 14 th day of treatment, the weight, fasting blood sugar (FBS) and on 28 th day blood glucose, K-Ras and GSK3 beta was measured. Results: In diabetic group blood GSK- 3 beta increase in comparison to control group (P < 0.05), also blood K-Ras decrease in the diabetic group (P < 0.05). Both extracts reduced GSK-3 beta level, however, this reduction was only statistically significant by U.dioica (P < 0.05). Compared to diabetic group, blood K-Ras level increased by both extract (P < 0.05). Also diabetes induction increase blood glucose levels and both extracts decrease its level significantly (P < 0.05).there is no significant differences among both extract effects on blood glucose, and K-Ras. Conclusion: For the first time shown that both extracts by regulating GSK-3 beta and K-Ras improve blood glucose level. More studies are needed to determine all the effects of these herbs.

• Journal of Periodontal and Implant Science
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• v.41 no.2
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• pp.92-97
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• 2011

Purpose: The present study was performed to compare the treatment outcomes of non-surgical periodontal treatment according to the distribution of attachment loss of a given patient. Methods: Forty-five patients with moderate to severe periodontitis were divided in two subgroups; Group I patients with teeth manifesting attachment loss of ${\geq}$ 6 mm at one or more sites on the buccal/labial aspect while maintaining an attachment level ${\leq}$ 5 mm at the lingual/palatal aspect, Group II patients with teeth manifesting an attachment level ${\geq}$ 6 mm at more than one site on the lingual/palatal aspect while maintaining an attachment level ${\leq}$ 5 mm at the buccal/labial aspect. The probing pocket depth, probing attachment level, tooth mobility, and chewing discomfort were recorded at baseline and 6 months examinations following non-surgical periodontal therapy. Results: The buccal/ abial surfaces of teeth with moderate to severe periodontitis in Group I patients demonstrated a greater amount of pocket reduction, gain of attachment level, and tooth mobility reduction than the lingual/palatal aspects of teeth examined in Group II patients. Conclusions: Within the limits of the present study, the patients demonstrating attachment loss ${\geq}$ 6 mm at buccal/labial surfaces responded better to the nonsurgical periodontal therapy than those demonstrating comparable attachment loss at lingual/ palatal surfaces.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.24 no.10B
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• pp.1971-1978
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• 1999

In this paper, we study the effects of long-range dependence (LRD) in VBR video traffic on queueing system. This paper consists of Part I and II. In Part I, we present a (LRD) video traffic model based on the shifting-level (SL) process. We observe that the ACF of an empirical video trace is accurately captured by the shifting-level process with compound correlation (SLCC): an exponential function in short range and a hyperbolic function in long range. We present an accurate parameter matching algorithm for video traffic. In the Part II, we offer the queueing analysis of SL/D/1/K called ‘quantization reduction method’. Comparing the queueing performances of the DAR(1) model and the SLCC with that of a real video trace, we identify the effects of SRD and LRD in VBR video traffic on queueing performance. Simulation results show that Markoivian models can estimate network performances fairly accurately under a moderate traffic load and buffer condition, whereas LRD may have a significant effect on queueing behavior under a heavy traffic load and large buffer condition.

• Journal of Nutrition and Health
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• v.30 no.10
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• pp.1180-1187
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• 1997

Cigarette smoking is a major risk factor of atherosclerosis and has been reported to contain an abundance of free radical species which could be expected to deplete antioxidants such as vitamin C . The present study was designed to investigate the relationship between smoking, plasma lipid and lipoprotein concentration, and plasma vitamin C level. Fifty-five healthy male smokers and 32 non-smokers were investigated in the study. Mean age, body weight , BMI and blood pressure made no differences in both smokers and non-smokers. Significantly, smokers has higher plasma total cholesterol and LDL-C , and lower HDL-C /LDL-C ratio compared with non-smokers. Plasma level of thiobartiturin acid reactive substances(TBARS), indicator of lipid peroxidation and increased susceptibility of LDL towards lipid perosidation, were elevated in smokers(p<0.001), while the plasma vitamin C level of smokers was significantly lower than that of non-smokers(p<0.05), indicating that elevated lipid peroxidation are associated with decreased plasma vitamin C content. In non-smokers a significantly positive correlation was observed between dietary vitamin C intake and plasma levels, but no such association observed in smokers. Lack of such a relationship and the decreased plasma vitamin C level in the smokers suggest that smoking may cause increased turnover of the plasma antioxidant. Consuquently, the sustained free radical load derived from smoking causes an imbalance in oxidant/antioxidant status and it could be expected that cigarette smoking renders plasma LDL more susceptible to oxidative modification . In the present study the possible explanations for that cigarette smokers have a higher risk of cardiovascular disease include the changes of blood lipid and lipoprotein concentration, and plasma vitamin C status which might have protective functions against free radicals -medaited lipid peroxidation.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.1
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• pp.571-578
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• 2013

Background: Patients with breast cancer can experience a feeling of hopelessness very deeply in the adjustment process, and the social support provided during this period can be effective in increasing the level of hope. The present study aimed to identify breast cancer patients' social support and hopelessness level. Materials and Methods: The target population of this analytical study was all breast cancer patients (total of 85) who had treatment in the oncology department of a university hospital located in Adana/Turkey and who met the inclusion criteria. Data were collected through "Personal Information Form", "Beck Hopelessness Scale (BHS)" and "Multidimensional Scale of Perceived Social Support" (MSPSS). Analysis was performed using Shapiro Wilk, One Way ANOVA Welch, Student t-test, Mann Whitney U, and Kruskall Wallis tests. Homogeneity of variance was tested with the Levene, Bonferroni and Games Howell tests. Mean scores and standard deviation values are given as descriptive statistics. Results: Average age of the participants with breast cancer is $48.6{\pm}10.6$. Of all the participants, 84.7% are married, 49.4% graduated from primary school, 81.2% are housewives, and 82.4% had children. The participants' multidimensional perceived social support total scores were found to be high ($57.41{\pm}13.97$) and hopelessness scale scores low ($5.49{\pm}3.80$). There was a reverse, linear relationship between hopelessness scale scores and social support total scores (r=-0.259, p=0.017). A statistically significant relationship was found between hopelessness scores and education level and having children, occupation, income status, and education level of spouses (p<0.05). Conclusions: The present study indicates that hopelessness of the patients with breast cancer decreased with the increase in their social support. Therefore, activating patient social support systems is of importance in increasing their level of hope.

• Journal of agricultural medicine and community health
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• v.19 no.2
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• pp.107-118
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• 1994

Health effects of pesticide among vinylhouse workers in Sangjoo County, Kyungpook Province were assessed by measuring cholinesterase, glutathion reductase, and methemoglobin. Activities of cholinesterases among vinylhouse workers and general farmers were 3.89U and 3.98U in serum and 5.29U and 5.50U in red blood cells, respectively. While levels of methemoglobin between vinylhouse workers(0.16%) and general farmers(0.17%) were very similar, glutathione reductase among vinylhouse workers were 8% lower than that of general farmers. Inhibition of RBC cholinesterase among vinylhouse workers was two times greater than general farmers, suggesting a greater exposure of vinylhouse workers to the organophosphate pesticides. Methemoglobin level among vinylhouse workers with more than or equal to 10 vinylhouse units was 13% higher than that of the workers with less than 10 units. Vinylhouse workers using protective gears during pesticide spray showed higher level of reduced glutathione and lower level of methemoglobin, as compared to the non-users. This indicates that protective gears play an important role against pesticide exposure. Vinylhouse workers practicing good personal hygiene showed a higher level of reduced glutathione, as compared to those with poor personal hygiene, indicating that personal hygiene is also an important factor in reducing pesticide exposure. The present study represents a first attempt to analyze cholinesterase, methemoglobin and glutathione reductase activities among the vinylhouse workers. While neither vinylhouse workers nor general farmers showed abnormal findings among biochemical parameters used in the present study, increased level of methemoglobin and decrease of glutathione reductase activity among vinylhouse workers suggest that these workers have been subject to a higher exposure of pesticide than general farmers.

• Journal of Nutrition and Health
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• v.32 no.3
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• pp.230-238
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• 1999

The present study was conducted to investigate te effect of sea tangle and hypoglycemic agent(Metformin) on lipid peroxidation and antioxidants levels in normal and diabetic rats. Male Sprague-Dawley rats were fed AIN-76 based experimental diets containing 5% (w/w) cellulose or 15%(w/w) sea tangle for 3 weeks, and then rats of diabetic groups were rendered diabetic by intramuscular injection of streptozotocin(STZ, 45mg/kg BW). After induction of diabetes Metformin(350mg/kg BW) was given once a day using a feeding tube for 5 days. Blood glucose level in diabetic rats fed sea tangle was significantly lower than that of diabetic rats fed cellulose. Metformin feeding resulted in further lowering blood glucose. Plasma and liver microsomal levels of lipid peroxides were increased significantly in diabetic rats as compared to normal rats, and the plasma level tended to be decreased by sea tangle feeding. Plasma level of retinol was reduced by STZ treatment, but it was increased by Metformin feeding in diabetic rats fed sea tangle. The liver contents of retinyl plamitate were reduced in diabetic rats but recovered by sea tangle feeding to some extent. Liver contents of total vitamin A were increased significantly by sea tangle in diabetic rats. Although difference in either plasma or liver level of $\alpha$-tocopherol by diet and STZ treatment was not significant, $\alpha$-tocopherol levels were the highest in the group with simultaneous feeding of sea tangle and metformin. Liver contents of zinc and copper were not influenced by either STZ treatment or sea tangle feeding. The present study indicates that the lowering blood glucose level could be attained by simultaneous trial of sea tangle diet and hypoglycemic agent and the increased oxidative stress caused by STZz treatment could be relieved by sea tangle feeding.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.31 no.4
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• pp.353-366
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• 2021

Objectives: An appropriate level of cost support is being proposed to maximize the participation rate. In addition, as the amount of support is highly concentrated at the level of the limit under the current level of supports, the level of cost support is low when the actual level of cost of measuring the working environment exceeds the limit. This paper describes the adjustment of an appropriate cost support rate. Methods: First, this paper analyzes the current cost support status using data from the KOSHA. Second, an alternative for adjusting the cost support rate is presented in consideration of the incentive aspect. Third, we present simulation results for the average cost support rate, the impact of each alternative on finance, and more. Fourth, the most desirable adjustment method is presented after comparing and analyzing the results of various alternatives. Results: In this paper, we present a new scale model. This model is a mixture of flat-rate, fixed rate, and subside cap. It is expected that the new model will not only facilitate participation in businesses with low measurement costs, but also have the effect of controlling measurement costs for institutions that incur greater costs. It is also expected that setting a cap will have the effect of considering government finances and inducing excessively costly institutions to reduce costs. Thus, the new model is likely to be superior to others. If the fourth plan is applied to new businesses and the fifth plan is applied to sustainable businesses, the average cost support rates will be 87.68 percent and 65.18 percent, respectively, and the needed finances will be 2.5 billion won, 18.8 billion won, and 21.3 billion won in total. Conclusions: It seems most desirable to introduce a new model that combines flat-rate, fixed-rate, and subsidy cap systems and achieve an appropriate cost support rate through this model.

• Spatial Information Research
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• v.15 no.1
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• pp.67-80
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• 2007

The land cover map represent the state of earth surfaces. It can be used as basic data to explore present conditions of earth surfaces and develop future plans for local areas. To produce the land cover map with efficiency, gathering geographic information from satellite images is important. Exporting, building, and managing processes on the land cover information are needed as well. In this study we aim to review the producing process of the level-2 land cover map in detail and enhance it. h present status of the producing process of the land cover map in Korea is reviewed, problems of the process are explored, and measures for improving it are proposed. The criteria for fixing boundaries and providing attributes for the land cover map are proposed. This proposed criteria may solve problems in a present producing process. The improving measures proposed in this study should be continuously revised in future studies.