• 지역사회간호학회지
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• 제14권4호
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• pp.598-607
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• 2003

Purpose: The purpose of this study was to identify the effects of the Sophrologic Prenatal Education Program. Method: The subjects of this study were 16 antepartum women who had been registered at community health centers at S-gu in Pusan. Data were collected from women who visited for antenatal care during the period from the 7th of May to 28th of June in 2003. Participants were evaluated before and on completion of the 8 weeks' educational program using 3 instruments: Breast-feeding knowlege, Maternal-fetal attachment and Antenatal stress. The Wilcoxon Signed-Ranks Test was conducted for data analysis using SPSS/WIN 10.0. Results: Statistically significant difference was found between the pretest and posttest in the mean score of the Breast-feeding knowledge. The mean scores of the experiment group and the control group were $31.44{\pm}5.51\;and\;37.06{\pm}4.27$ respectively (p=.001). No statistically significant difference was found between the pretest and posttest in the mean score of the Maternal-fetal attachment (p=.315, p=.578). Conclusions: Community health care providers must consider the emotional needs of Korean people and make efforts to adapt the Sophrologie Prenatal Education Program for a larger number of antepartum women in community.

• 대한한방부인과학회지
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• 제15권4호
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• pp.149-162
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• 2002

The fetus is greatly influenced by mother's health condition and her environment. So in our traditional society, the prenatal care is regarded as important for generations to birth of sound baby in mind and boy. Purpose : We aimed to reserch what kind of mother's conditions can be more influential to infant allergic disease among traditional prenatal care. Method : We investigated 91 patients who answered by a questionnaire at Dept. of Pediatrics, Oriental Hospital of Dae-jeon University. We divided patients into two groups, A(normal group;43) and B(allergic disease group;48) and analyzed those. Results : The pregnant women in the group B, generally have worse health conditions and are under the stress mentally and cannot get enough nutrition because of morning sickness and digestive trouble, but take more pungent and powdered food than the group A. Specially, the result is significant in anger and worry among other mental stresses and in digestive trouble and threatened abortion among other health conditions(according to order: p<0.001, p<0.05, p<0.01, p<0.001). We can see that pregnant woman's peaceful mentality and enough nutrition intake are most important to birth of sound baby in mind and also we can see that pregnant woman's regimen has influence on not only infant disease but also character and the infant allergic diseases are related to inheritable factor.

• Child Health Nursing Research
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• 제11권3호
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• pp.290-300
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• 2005

Purpose: The purpose of this study was to identify the factors influencing parenting stress in primiparas. Method: The participants in this study were 198 primiparas of infants aged 1-6 months who visited well baby clinics in 5 hospitals. The data were collected from April 15 to June 15, 2003. Results: The mean score for parenting stress was 2.4 of a possible 5 and thus considered average. The score for parenting stress was significantly correlated with the level of maternal perception of the infant and the level of social support. The score for parenting stress was significantly different according to the education level of the primiparas and prenatal management. For the primiparas, social support($20\%$) and maternal perception of the infant($9\%$) were significant predictors explaining parenting stress. Conclusions: Nursing interventions to improve maternal perception of the infant and increase social support should be provided for primiparas in order to reduce parenting stress.

• Child Health Nursing Research
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• 제11권4호
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• pp.415-426
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• 2005

Purpose: The purpose of this study was to identify relations among the parenting stress, maternal sensitivity to infant cues, parenting environment of first-time mothers. Method: The participants were 194 first-time mothers of babies aged 1-6 months who visited well-baby clinics in 5 hospitals. The data were collected from April 15 to June 15, 2003. Results: The parenting stress level was moderate with a mean score of 2.4(range 1-5). The parent domain and parent-child relationship domain of the parenting stress scale were significantly correlated with maternal sensitivity to infant feeding cues (r=-.178, p<.05; r=-.197, p<.01). Parenting stress was significantly correlated with childrearing environment(r=-2.19, p<.01). Parenting stress and childrearing environment were significantly different according to the educational level of the mothers and their prenatal care. Conclusions: Nursing interventions to reduce parenting stress in first-time mothers are needed to improve maternal sensitivity to infant cues and childrearing environment which foster infant development.

• 여성건강간호학회지
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• 제20권3호
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• pp.195-203
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• 2014

Purpose: The objective of this study was to investigate the relationship between fatigue, sleep disturbance, and gestational stress in women during late stage of pregnancy. Methods: This study was conducted with 113 healthy pregnant women at gestational age greater than 27 weeks who were registered at community health centers and received prenatal care. A structured questionnaire regarding fatigue, sleep disturbance, and gestational stress was used. The data was analyzed using a t-test, an ANOVA, and Pearson correlation coefficients. Results: The subjects with unplanned pregnancies and irregular exercise patterns showed a higher level of fatigue than those with planned pregnancies and regular exercise patterns. Pregnant women with caffeine intake manifested higher levels of gestational stress and sleep disturbance than those without. The levels of sleep disturbance and gestational stress increased as the fatigue levels increased. The fatigue levels increased with increased levels of sleep disturbance. Conclusion: Planned pregnancy, regular exercise patterns, and caffeine intake were related with fatigue, sleep disturbance, and gestational stress in women during late stages of pregnancy. Fatigue, sleep disturbance, and gestational stress had close associations to each other. In the future, such results should guide development of nursing intervention programs for women in late stages of pregnancy.

• Toxicological Research
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• 제20권3호
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• pp.187-193
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• 2004

This study aimed to determine the association of maternal oxidative stress and adverse pregnancy outcome with serum vitamin C concentration and a myeloperoxidase (MPO) genetic polymorphism during pregnancy. We investigated 450 pregnant women who visited Ewha Womans University Hospital for prenatal care during gestational weeks 24～28. During the second trimester, we measured serum vitamin C levels and urinary 8-hydroxyde-2'-deoxyguanosine (8-OHdG) and malondialdehyde (MDA) as an oxidative stress biomarker. We determined the presence of a maternal MPO polymorphism (G-to-A substitution at nucleotide 463) using a PCR-RFLP assay. We compared the level of oxidative stress and birth weight with the vitamin C concentration and the presence of the MPO polymorphism. The mean level of maternal oxidative stress tended to be higher and the birth weight lower for MPO type A/A than for types A/G and G/G. Vitamin C levels above the 75 percentiles were associated with reduced concentrations of urinary MDA and 8-OHdG but increased birth weight. Our data demonstrate that oxidative stress and neonatal birth weight are associated with the MPO genetic polymorphism, with the association modified by the maternal vita-min C levels.

• 한국응급구조학회지
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• 제18권3호
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• pp.77-90
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• 2014

Purpose: This study was a descriptive survey research that aimed to investigate the stress level of pregnant women and subsequent effect of emergency cesarean delivery on anxiety and subjective anxiety statuses. Methods: The study samples were 233, including 109 emergency cesarean delivery and 124 normal vaginal deliveries between May 1, 2014, and August 26, 2014, in the Gwangju Metropolitan City. Results: None of the results showed any significant statistical difference in psychological stress between emergency cesarean delivery during mid-pregnancy and normal vaginal delivery (t = 1.784, p = .076). Emergency cesarean delivery has a significantly high level of anxiety (t = 10.849, p < .001) and subjective anxiety statuses (t = 13.294, p < .001) compared with normal vaginal delivery. Conclusion: A prenatal education program for stress and anxiety from emergency cesarean delivery needs to be developed for more effective stress management.

• Journal of Nutrition and Health
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• 제16권4호
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• pp.243-252
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• 1983

This study was undertaken to invesigate the effect of early nutritional deprivation and environment on neurotransmitter concentrations and behavior in later life. The restoring process of rats fed foods ad libitum after 50% restriction of the casein or the Korean diet during the prenatal and/or the lactating periods was observed. There were two rearing conditions, isolated and enriched, after weaning. Behavioral development was measured by the Y- shaped water maze and the open field test. The neurotransmitters were analyzed after sacrifice at the age of 21 weeks. The results are summarized as follows. 1) The body weight impairment by dietary restriction during the prenatal and lactating periods could be restored within 18 weeks after weaning in case of living in a classical cage. The effect of quantitative restriction was bigger in the Korean diet than in the casein diet. 2) The brain weight was decreased by nutritional deprivation. Environmental enrichment increased it slightly. 3) The concentration of neurotransmitters, norepinephrine, dopamine, and serotonin, were not shown any traces of the dietary restriction at the age of 21 weeks. 4) In the maze test, the deprived rats made more errors than the nourished and the rats fed the Korean diet more than those fed the cascin dict. The environmental enrichment could decrease the number of errors. 5) In the open field test, the dietary deprived groups showed less reaction time, more squares entered in the field, and less number of fecal boli than the nourished among the environmentally isolated rats. However, rats living in the enriched cage without experience of nutritional stress showed the lowest emotionality and the elevated exploratory activity.

• 한국환경성돌연변이발암원학회:학술대회논문집
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• 한국환경성돌연변이발암원학회 2002년도 Current Trends in Toxicological Sciences
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• pp.48-64
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• 2002

The primary recognized health risk from common deficiencies in glucose-6-phosphate dehydrogenase (G6PD), a cytoprotective enzyme for oxidative stress, is red blood cell hemolysis. Here we show that litters from untreated pregnant mutant mice with a hereditary G6PD deficiency had increased prenatal (fetal resorptions) and postnatal death. When treated with the anticonvulsant drug phenytoin, a human teratogen that is commonly used in pregnant women and causes embryonic oxidative stress, G6PD-deficient dams had higher embryonic DNA oxidation and more fetal death and birth defects. The reported G6PD gene mutation was confirmed and used to genotype fetal resorptions, which were primarily G6PD deficient. This is the first evidence that G6PD is a developmentally critical cytoprotective enzyme for both endogenous and xenobiotic-initiated embryopathic oxidative stress and DNA damage. G6PD deficiencies accordingly may have a broader biological relevance as important determinants of infertility, in utero and postnatal death, and teratogenesis.-Nicol, C. J., Zielenski, J., Tsui, L.-C., Wells, P. G. An embryoprotective role for glucose-6-phosphate dehydrogenase in developmental oxidative stress and chemical teratogenesis.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제26권2호
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• pp.112-119
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• 2015

Objectives : The purpose of this study was to examine the prenatal, perinatal and developmental risk factors of attention-deficit hyperactivity disorder (ADHD), compared to unaffected siblings (SIB), and typically developing children (TC). Methods : Subjects with ADHD, their SIB, and TC were recruited from the child psychiatry outpatient clinic of the Asan Medical Center Children's Hospital. The parents of the children completed questionnaires on perinatal and developmental risk factors. Results : Fifty-eight subjects with ADHD (41 boys, $7.7{\pm}1.3years$), 21 SIB (8 boys, $8.2{\pm}1.8years$), and 22 TC (8 boys, $8.5{\pm}2.1years$) were included. The ADHD group showed higher rates of maternal stress during pregnancy than the SIB group (p=.002), and the ADHD group showed higher rates of familial psychiatric history than the TC (odds ratio, 8.76 ; 95% confidence interval, 1.69 to 45.45). Conclusion : These findings suggest that among perinatal and developmental factors, maternal stress during pregnancy contribute to the development of ADHD. Future prospective studies will be needed in order to determine the causal relationship between perinatal risk factors and development of ADHD.