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http://dx.doi.org/10.5765/jkacap.2015.26.2.112

Prenatal, Perinatal and Developmental Risk Factors of Attention-Deficit Hyperactivity Disorder  

Yeo, Jin-Young (Didim Psychiatric Clinic)
Choi, Sejin (Didim Psychiatric Clinic)
Joo, Yeon Ho (Department of Psychiatry, Asan Medical Center, University of Ulsan College of Medicine)
Kim, Hyo-Won (Department of Psychiatry, Asan Medical Center, University of Ulsan College of Medicine)
Publication Information
Journal of the Korean Academy of Child and Adolescent Psychiatry / v.26, no.2, 2015 , pp. 112-119 More about this Journal
Abstract
Objectives : The purpose of this study was to examine the prenatal, perinatal and developmental risk factors of attention-deficit hyperactivity disorder (ADHD), compared to unaffected siblings (SIB), and typically developing children (TC). Methods : Subjects with ADHD, their SIB, and TC were recruited from the child psychiatry outpatient clinic of the Asan Medical Center Children's Hospital. The parents of the children completed questionnaires on perinatal and developmental risk factors. Results : Fifty-eight subjects with ADHD (41 boys, $7.7{\pm}1.3years$), 21 SIB (8 boys, $8.2{\pm}1.8years$), and 22 TC (8 boys, $8.5{\pm}2.1years$) were included. The ADHD group showed higher rates of maternal stress during pregnancy than the SIB group (p=.002), and the ADHD group showed higher rates of familial psychiatric history than the TC (odds ratio, 8.76 ; 95% confidence interval, 1.69 to 45.45). Conclusion : These findings suggest that among perinatal and developmental factors, maternal stress during pregnancy contribute to the development of ADHD. Future prospective studies will be needed in order to determine the causal relationship between perinatal risk factors and development of ADHD.
Keywords
Attention-Deficit/Hyperactivity Disorder; Developmental Risk Factors; Perinatal Risk Factors; Siblings;
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